Angioedema Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description condition similar to urticarai but with swelling occuring in a lower layer of the dermis as well as in the subcutis (Experimental Factor Ontology, EFO_0005532)
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D000799
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Genes

590 genes/proteins associated with the disease Angioedema from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
PLAT plasminogen activator, tissue 2.88009
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 2.88009
HLA-DPB1 major histocompatibility complex, class II, DP beta 1 2.88009
XPNPEP2 X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound 2.88009
ALB albumin 2.88009
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 2.88009
TNF tumor necrosis factor 2.53445
REN renin 2.50577
CASP3 caspase 3, apoptosis-related cysteine peptidase 2.48932
IL6 interleukin 6 2.48467
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 2.47782
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 2.45104
TGFB1 transforming growth factor, beta 1 2.44646
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 2.4419
IL1B interleukin 1, beta 2.41951
BCL2 B-cell CLL/lymphoma 2 2.41809
CCL2 chemokine (C-C motif) ligand 2 2.41534
NOS2 nitric oxide synthase 2, inducible 2.37637
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 2.37063
VEGFA vascular endothelial growth factor A 2.36118
SLC22A2 solute carrier family 22 (organic cation transporter), member 2 2.34165
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 2.34103
EDN1 endothelin 1 2.33238
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 2.33171
FOS FBJ murine osteosarcoma viral oncogene homolog 2.32172
CXCL8 chemokine (C-X-C motif) ligand 8 2.31319
MMP2 matrix metallopeptidase 2 2.31266
NPPA natriuretic peptide A 2.30964
MPO myeloperoxidase 2.30629
IL10 interleukin 10 2.29506
IL4 interleukin 4 2.28718
BAX BCL2-associated X protein 2.28339
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 2.27795
IFNG interferon, gamma 2.27152
MAPK1 mitogen-activated protein kinase 1 2.26724
NOS3 nitric oxide synthase 3 (endothelial cell) 2.2622
MAPK3 mitogen-activated protein kinase 3 2.25239
IL1A interleukin 1, alpha 2.2351
PPARG peroxisome proliferator-activated receptor gamma 2.22949
CAT catalase 2.21823
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 2.21204
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 2.20959
FAS Fas cell surface death receptor 2.20568
VCAM1 vascular cell adhesion molecule 1 2.19767
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 2.14348
CASP8 caspase 8, apoptosis-related cysteine peptidase 2.14036
ICAM1 intercellular adhesion molecule 1 2.13857
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 2.13436
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2 2.12553
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 2.1224
SOD2 superoxide dismutase 2, mitochondrial 2.12091
CASP9 caspase 9, apoptosis-related cysteine peptidase 2.11258
MMP9 matrix metallopeptidase 9 2.10963
DDIT3 DNA-damage-inducible transcript 3 2.10719
FASLG Fas ligand (TNF superfamily, member 6) 2.08929
IL2 interleukin 2 2.0874
COL1A1 collagen, type I, alpha 1 2.08368
ACE angiotensin I converting enzyme 2.06809
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 2.06735
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8 2.0644
CCND1 cyclin D1 2.05168
CCL3 chemokine (C-C motif) ligand 3 2.04437
SLC22A1 solute carrier family 22 (organic cation transporter), member 1 2.02905
SPP1 secreted phosphoprotein 1 2.02865
NPPB natriuretic peptide B 2.01897
JUN jun proto-oncogene 2.01649
AKT1 v-akt murine thymoma viral oncogene homolog 1 2.00661
IL5 interleukin 5 2.00219
IGF1 insulin-like growth factor 1 (somatomedin C) 1.98353
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 1.98253
TIMP1 TIMP metallopeptidase inhibitor 1 1.97785
SLC22A7 solute carrier family 22 (organic anion transporter), member 7 1.97111
EGFR epidermal growth factor receptor 1.95812
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 1.95631
CTGF connective tissue growth factor 1.95435
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.9492
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.91944
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1 1.90919
BDNF brain-derived neurotrophic factor 1.90542
SLC15A1 solute carrier family 15 (oligopeptide transporter), member 1 1.90525
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 1.90525
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.90476
HMOX1 heme oxygenase 1 1.90392
INS insulin 1.89894
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 1.8965
MAPK8 mitogen-activated protein kinase 8 1.88589
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 1.8854
AGTR1 angiotensin II receptor, type 1 1.88092
PRL prolactin 1.87858
RB1 retinoblastoma 1 1.87825
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.87725
TP53 tumor protein p53 1.85957
ADIPOQ adiponectin, C1Q and collagen domain containing 1.85712
SELL selectin L 1.85573
DUSP1 dual specificity phosphatase 1 1.85415
EGR1 early growth response 1 1.85046
SLC22A9 solute carrier family 22 (organic anion transporter), member 9 1.84799
ADRB1 adrenoceptor beta 1 1.83503
TIMP2 TIMP metallopeptidase inhibitor 2 1.83042
NR1I2 nuclear receptor subfamily 1, group I, member 2 1.82743
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 1.81921
GSK3B glycogen synthase kinase 3 beta 1.81866
LEP leptin 1.81484
COL3A1 collagen, type III, alpha 1 1.80661
BIRC5 baculoviral IAP repeat containing 5 1.79981
MAPK14 mitogen-activated protein kinase 14 1.79675
BCL2L1 BCL2-like 1 1.7893
SOD1 superoxide dismutase 1, soluble 1.78663
GSTP1 glutathione S-transferase pi 1 1.77686
POMC proopiomelanocortin 1.76966
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 1.7652
CYBA cytochrome b-245, alpha polypeptide 1.76052
CYBB cytochrome b-245, beta polypeptide 1.75817
KNG1 kininogen 1 1.75817
MMP3 matrix metallopeptidase 3 1.7568
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 1.75142
PPARA peroxisome proliferator-activated receptor alpha 1.75102
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 1.74984
CLU clusterin 1.74139
PCNA proliferating cell nuclear antigen 1.73938
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 1.73495
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 1.73353
ADRB2 adrenoceptor beta 2, surface 1.72034
STAR steroidogenic acute regulatory protein 1.7185
NCF1 neutrophil cytosolic factor 1 1.71524
CXCL10 chemokine (C-X-C motif) ligand 10 1.69846
PARP1 poly (ADP-ribose) polymerase 1 1.69825
ACTA2 actin, alpha 2, smooth muscle, aorta 1.6906
MMP1 matrix metallopeptidase 1 1.68804
FOXO1 forkhead box O1 1.68253
SCD stearoyl-CoA desaturase (delta-9-desaturase) 1.67289
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) 1.66813
CASP7 caspase 7, apoptosis-related cysteine peptidase 1.6662
CDK2 cyclin-dependent kinase 2 1.66533
NGFR nerve growth factor receptor 1.66339
FN1 fibronectin 1 1.65974
MMP13 matrix metallopeptidase 13 1.62983
CCL5 chemokine (C-C motif) ligand 5 1.62983
F3 coagulation factor III (thromboplastin, tissue factor) 1.62758
NFE2L2 nuclear factor, erythroid 2-like 2 1.6249
SELP selectin P (granule membrane protein 140kDa, antigen CD62) 1.62445
MYH7 myosin, heavy chain 7, cardiac muscle, beta 1.6199
NGF nerve growth factor (beta polypeptide) 1.61713
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1 1.61342
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 1.61154
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 1.60897
CXCL2 chemokine (C-X-C motif) ligand 2 1.60524
G6PD glucose-6-phosphate dehydrogenase 1.5992
NR1I3 nuclear receptor subfamily 1, group I, member 3 1.59873
AKR1C3 aldo-keto reductase family 1, member C3 1.59591
GCLM glutamate-cysteine ligase, modifier subunit 1.59591
TLR4 toll-like receptor 4 1.59567
NQO1 NAD(P)H dehydrogenase, quinone 1 1.58678
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 1.58398
CRH corticotropin releasing hormone 1.57712
CCND3 cyclin D3 1.57018
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 1.57018
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 1.55846
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2 1.5555
BDKRB1 bradykinin receptor B1 1.55108
SELE selectin E 1.54937
CALCA calcitonin-related polypeptide alpha 1.54499
CYCS cytochrome c, somatic 1.53796
S100A9 S100 calcium binding protein A9 1.53796
SLC22A3 solute carrier family 22 (organic cation transporter), member 3 1.53258
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 1.5254
CASP6 caspase 6, apoptosis-related cysteine peptidase 1.51481
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5 1.5133
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) 1.5128
TIMP3 TIMP metallopeptidase inhibitor 3 1.51205
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 1.51004
IL12B interleukin 12B 1.50549
VIM vimentin 1.50549
FADS2 fatty acid desaturase 2 1.50398
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 1.49533
F2 coagulation factor II (thrombin) 1.48633
NOX4 NADPH oxidase 4 1.48582
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 1.48582
CFLAR CASP8 and FADD-like apoptosis regulator 1.48531
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 1.48505
ODC1 ornithine decarboxylase 1 1.48351
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17 1.47991
CDK4 cyclin-dependent kinase 4 1.47193
PPP1R15A protein phosphatase 1, regulatory subunit 15A 1.47115
TH tyrosine hydroxylase 1.47038
FASN fatty acid synthase 1.47038
EDNRB endothelin receptor type B 1.46909
OXT oxytocin/neurophysin I prepropeptide 1.46568
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 1.46568
LDLR low density lipoprotein receptor 1.4633
TAGLN transgelin 1.46277
GSTM1 glutathione S-transferase mu 1 1.46251
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 1.46198
SLC22A8 solute carrier family 22 (organic anion transporter), member 8 1.46015
SLC22A6 solute carrier family 22 (organic anion transporter), member 6 1.45458
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 1.45458
CCNE1 cyclin E1 1.45431
NOX1 NADPH oxidase 1 1.44982
FSHB follicle stimulating hormone, beta polypeptide 1.44845
XBP1 X-box binding protein 1 1.44626
MKI67 marker of proliferation Ki-67 1.44463
EGF epidermal growth factor 1.44463
HGF hepatocyte growth factor (hepapoietin A; scatter factor) 1.43974
IGFBP1 insulin-like growth factor binding protein 1 1.43974
AR androgen receptor 1.43727
POSTN periostin, osteoblast specific factor 1.43618
ATF4 activating transcription factor 4 1.43537
CD36 CD36 molecule (thrombospondin receptor) 1.43347
CAMK2A calcium/calmodulin-dependent protein kinase II alpha 1.43239
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 1.43212
IL18 interleukin 18 1.42994
CAV1 caveolin 1, caveolae protein, 22kDa 1.42885
CD44 CD44 molecule (Indian blood group) 1.42454
APOE apolipoprotein E 1.42454
IGF1R insulin-like growth factor 1 receptor 1.42266
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 1.42238
GJA1 gap junction protein, alpha 1, 43kDa 1.42101
FABP4 fatty acid binding protein 4, adipocyte 1.42047
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 1.41965
XDH xanthine dehydrogenase 1.41775
PRKCE protein kinase C, epsilon 1.41721
FGF2 fibroblast growth factor 2 (basic) 1.41586
PENK proenkephalin 1.41478
S100A8 S100 calcium binding protein A8 1.41478
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 1.41424
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1 1.41008
COL1A2 collagen, type I, alpha 2 1.41008
GPX2 glutathione peroxidase 2 1.4098
AKR1C1 aldo-keto reductase family 1, member C1 1.40815
THBS1 thrombospondin 1 1.40705
AGTR2 angiotensin II receptor, type 2 1.4065
MYH6 myosin, heavy chain 6, cardiac muscle, alpha 1.39813
GFAP glial fibrillary acidic protein 1.39785
PDE4B phosphodiesterase 4B, cAMP-specific 1.3973
GPX1 glutathione peroxidase 1 1.39366
MAP2K2 mitogen-activated protein kinase kinase 2 1.39226
PLIN2 perilipin 2 1.39114
ASNS asparagine synthetase (glutamine-hydrolyzing) 1.39002
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3 1.38918
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 1.38641
IGF2 insulin-like growth factor 2 1.3827
HSPA1A heat shock 70kDa protein 1A 1.38043
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 1.38043
TAC1 tachykinin, precursor 1 1.38043
HSPD1 heat shock 60kDa protein 1 (chaperonin) 1.37817
PGRMC1 progesterone receptor membrane component 1 1.37418
POR P450 (cytochrome) oxidoreductase 1.37389
LHB luteinizing hormone beta polypeptide 1.37217
TGFB2 transforming growth factor, beta 2 1.36876
HDC histidine decarboxylase 1.36735
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 1.36447
MYL9 myosin, light chain 9, regulatory 1.36361
HMGB1 high mobility group box 1 1.3619
GSTT1 glutathione S-transferase theta 1 1.36104
DES desmin 1.35991
GAL galanin/GMAP prepropeptide 1.35991
NPHS1 nephrosis 1, congenital, Finnish type (nephrin) 1.35906
FKBP5 FK506 binding protein 5 1.35618
SMAD7 SMAD family member 7 1.35618
CRP C-reactive protein, pentraxin-related 1.3556
CCNA2 cyclin A2 1.35328
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 1.35271
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 1.34926
CCND2 cyclin D2 1.3484
HSPA8 heat shock 70kDa protein 8 1.34811
IL12A interleukin 12A 1.34635
AKR1C2 aldo-keto reductase family 1, member C2 1.34635
TUBA1A tubulin, alpha 1a 1.34547
ADRB3 adrenoceptor beta 3 1.34547
CAPN2 calpain 2, (m/II) large subunit 1.34547
AVP arginine vasopressin 1.34518
CTSB cathepsin B 1.34198
LCN2 lipocalin 2 1.34198
LOX lysyl oxidase 1.33966
NR0B2 nuclear receptor subfamily 0, group B, member 2 1.33966
SLC22A11 solute carrier family 22 (organic anion/urate transporter), member 11 1.3385
PTEN phosphatase and tensin homolog 1.33731
H2AFX H2A histone family, member X 1.33731
GDF15 growth differentiation factor 15 1.33731
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 1.33701
CPT1A carnitine palmitoyltransferase 1A (liver) 1.33316
CES2 carboxylesterase 2 1.33169
PPARD peroxisome proliferator-activated receptor delta 1.33169
JUND jun D proto-oncogene 1.33169
C3 complement component 3 1.3311
PDGFB platelet-derived growth factor beta polypeptide 1.32103
CX3CL1 chemokine (C-X3-C motif) ligand 1 1.31837
CCNB1 cyclin B1 1.31807
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11 1.31596
MCL1 myeloid cell leukemia 1 1.31596
NR3C2 nuclear receptor subfamily 3, group C, member 2 1.31506
SLC12A3 solute carrier family 12 (sodium/chloride transporter), member 3 1.31237
PKM pyruvate kinase, muscle 1.31089
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 1.31
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b 1.3085
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 1.30819
CASP1 caspase 1, apoptosis-related cysteine peptidase 1.3039
CD86 CD86 molecule 1.3039
RHOA ras homolog family member A 1.30329
PTK2 protein tyrosine kinase 2 1.30329
IL13 interleukin 13 1.29996
UNG uracil-DNA glycosylase 1.29875
CCNG2 cyclin G2 1.29875
UGT2B7 UDP glucuronosyltransferase 2 family, polypeptide B7 1.29875
TGFA transforming growth factor, alpha 1.29564
HSF1 heat shock transcription factor 1 1.29564
TGFB3 transforming growth factor, beta 3 1.29564
ECHS1 enoyl CoA hydratase, short chain, 1, mitochondrial 1.29533
CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2 1.29256
TLR2 toll-like receptor 2 1.29072
NOS1 nitric oxide synthase 1 (neuronal) 1.2898
APP amyloid beta (A4) precursor protein 1.28796
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 1.28734
UGT1A10 UDP glucuronosyltransferase 1 family, polypeptide A10 1.2861
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 1.2861
GH1 growth hormone 1 1.28579
KLF4 Kruppel-like factor 4 (gut) 1.28303
GCLC glutamate-cysteine ligase, catalytic subunit 1.28303
GCG glucagon 1.28303
IGFBP3 insulin-like growth factor binding protein 3 1.2818
ANGPTL4 angiopoietin-like 4 1.28119
IL2RA interleukin 2 receptor, alpha 1.28027
VCAN versican 1.27905
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1 1.27905
DUT deoxyuridine triphosphatase 1.27905
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1.27595
HRH1 histamine receptor H1 1.27132
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) 1.27101
UGT1A8 UDP glucuronosyltransferase 1 family, polypeptide A8 1.27101
CKM creatine kinase, muscle 1.27101
NRP1 neuropilin 1 1.26825
BID BH3 interacting domain death agonist 1.26794
INSIG1 insulin induced gene 1 1.267
IL1RN interleukin 1 receptor antagonist 1.267
NPY neuropeptide Y 1.267
HSPA1B heat shock 70kDa protein 1B 1.26483
PER1 period circadian clock 1 1.26329
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic 1.26236
TYMP thymidine phosphorylase 1.2596
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 1.25868
AHR aryl hydrocarbon receptor 1.25776
INSR insulin receptor 1.25682
MAP2K1 mitogen-activated protein kinase kinase 1 1.25557
INHBA inhibin, beta A 1.254
MMP14 matrix metallopeptidase 14 (membrane-inserted) 1.25121
PRLR prolactin receptor 1.25121
GADD45A growth arrest and DNA-damage-inducible, alpha 1.25121
TXNRD1 thioredoxin reductase 1 1.24935
DRD2 dopamine receptor D2 1.24935
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 1.24843
FOSB FBJ murine osteosarcoma viral oncogene homolog B 1.2456
PLAUR plasminogen activator, urokinase receptor 1.24244
E2F1 E2F transcription factor 1 1.24244
ATF3 activating transcription factor 3 1.23868
FDFT1 farnesyl-diphosphate farnesyltransferase 1 1.23743
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 1.23584
ARC activity-regulated cytoskeleton-associated protein 1.23392
BDKRB2 bradykinin receptor B2 1.23042
UGT1A6 UDP glucuronosyltransferase 1 family, polypeptide A6 1.22948
EIF4E eukaryotic translation initiation factor 4E 1.22696
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 1.22534
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 1.22534
ANGPT2 angiopoietin 2 1.22534
RYR2 ryanodine receptor 2 (cardiac) 1.22534
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1 1.22048
HRAS Harvey rat sarcoma viral oncogene homolog 1.21984
TFRC transferrin receptor 1.21984
FOSL2 FOS-like antigen 2 1.21984
RPS6 ribosomal protein S6 1.21855
AQP2 aquaporin 2 (collecting duct) 1.21759
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B 1.21663
MTUS1 microtubule associated tumor suppressor 1 1.21599
CCL20 chemokine (C-C motif) ligand 20 1.21599
CREB1 cAMP responsive element binding protein 1 1.21534
CTSD cathepsin D 1.21468
SQSTM1 sequestosome 1 1.21271
ACVR1B activin A receptor, type IB 1.21108
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 1.21076
SAT1 spermidine/spermine N1-acetyltransferase 1 1.20978
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) 1.20654
ESR1 estrogen receptor 1 1.20493
ACE2 angiotensin I converting enzyme 2 1.20427
CP ceruloplasmin (ferroxidase) 1.20229
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) 1.19999
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit 1.19999
TJP3 tight junction protein 3 1.19737
JAK1 Janus kinase 1 1.19672
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled 1.19542
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 1.19312
UCK2 uridine-cytidine kinase 2 1.1908
ARNT aryl hydrocarbon receptor nuclear translocator 1.19047
LPL lipoprotein lipase 1.18948
ACADL acyl-CoA dehydrogenase, long chain 1.18882
FADD Fas (TNFRSF6)-associated via death domain 1.18685
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1 1.18456
ARNTL aryl hydrocarbon receptor nuclear translocator-like 1.18456
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 1.18391
MT1A metallothionein 1A 1.18259
BCL2L11 BCL2-like 11 (apoptosis facilitator) 1.1786
SCN1B sodium channel, voltage gated, type I beta subunit 1.17827
AP1S1 adaptor-related protein complex 1, sigma 1 subunit 1.17827
UGT1A3 UDP glucuronosyltransferase 1 family, polypeptide A3 1.17761
KDR kinase insert domain receptor 1.17662
RXRA retinoid X receptor, alpha 1.17662
ALAS2 5'-aminolevulinate synthase 2 1.17596
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 1.17464
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 1.173
SMAD4 SMAD family member 4 1.17202
RRM2 ribonucleotide reductase M2 1.17134
TEX261 testis expressed 261 1.16933
CCNB2 cyclin B2 1.16666
KCND2 potassium channel, voltage gated Shal related subfamily D, member 2 1.16633
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5 1.16633
BTG1 B-cell translocation gene 1, anti-proliferative 1.16567
CREM cAMP responsive element modulator 1.16567
GSTM2 glutathione S-transferase mu 2 (muscle) 1.16368
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon 1.15967
GSTA2 glutathione S-transferase alpha 2 1.15967
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4 1.15763
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase) 1.15661
REL v-rel avian reticuloendotheliosis viral oncogene homolog 1.1556
BAK1 BCL2-antagonist/killer 1 1.1529
MSMO1 methylsterol monooxygenase 1 1.15089
MAOA monoamine oxidase A 1.15055
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 1.15055
CNR1 cannabinoid receptor 1 (brain) 1.14404
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta 1.14336
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 1.14336
CCL11 chemokine (C-C motif) ligand 11 1.14234
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 1.14166
NUPR1 nuclear protein, transcriptional regulator, 1 1.14166
CD40LG CD40 ligand 1.1403
FAAH fatty acid amide hydrolase 1.1403
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) 1.13963
CBR1 carbonyl reductase 1 1.13929
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1 1.13793
MBP myelin basic protein 1.13655
RBL2 retinoblastoma-like 2 1.13655
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 1.13655
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 1.13621
BAD BCL2-associated agonist of cell death 1.13449
TRIB3 tribbles pseudokinase 3 1.13075
GATA4 GATA binding protein 4 1.12906
BMP7 bone morphogenetic protein 7 1.12906
DBI diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) 1.12906
EIF5 eukaryotic translation initiation factor 5 1.12906
GNAS GNAS complex locus 1.12838
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4 1.12288
BMP4 bone morphogenetic protein 4 1.12288
CCNC cyclin C 1.12185
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 1.12185
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal 1.12185
HPN hepsin 1.12185
FOXO3 forkhead box O3 1.12014
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 1.12014
DHFR dihydrofolate reductase 1.11741
CDK5 cyclin-dependent kinase 5 1.11707
COL4A2 collagen, type IV, alpha 2 1.11673
SERINC3 serine incorporator 3 1.11673
PRDX2 peroxiredoxin 2 1.11501
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 1.11501
FBXO32 F-box protein 32 1.11466
SREBF1 sterol regulatory element binding transcription factor 1 1.11396
IGFBP5 insulin-like growth factor binding protein 5 1.1122
GLDC glycine dehydrogenase (decarboxylating) 1.11186
PDGFA platelet-derived growth factor alpha polypeptide 1.10977
PRNP prion protein 1.10977
CYP3A cytochrome P450, family 3, subfamily A 1.10769
FADS1 fatty acid desaturase 1 1.10769
EDNRA endothelin receptor type A 1.10699
PDPK1 3-phosphoinositide dependent protein kinase 1 1.10665
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2 1.10665
NME2 NME/NM23 nucleoside diphosphate kinase 2 1.10665
SHMT1 serine hydroxymethyltransferase 1 (soluble) 1.10665
GSR glutathione reductase 1.10424
STC2 stanniocalcin 2 1.10424
KLF5 Kruppel-like factor 5 (intestinal) 1.10424
FOSL1 FOS-like antigen 1 1.10388
SLCO2A1 solute carrier organic anion transporter family, member 2A1 1.10211
BMP2K BMP2 inducible kinase 1.10069
MT1X metallothionein 1X 1.10069
AKT2 v-akt murine thymoma viral oncogene homolog 2 1.10069
TAT tyrosine aminotransferase 1.10069
CASP2 caspase 2, apoptosis-related cysteine peptidase 1.09927
ANG angiogenin, ribonuclease, RNase A family, 5 1.09716
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 1.09716
PHYH phytanoyl-CoA 2-hydroxylase 1.09681
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 1.09436
PLG plasminogen 1.09401
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 1.09401
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 1.09401
CAMK4 calcium/calmodulin-dependent protein kinase IV 1.09226
COL4A1 collagen, type IV, alpha 1 1.08726
LDHB lactate dehydrogenase B 1.08726
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal) 1.08655
GSTA1 glutathione S-transferase alpha 1 1.08584
HSPB1 heat shock 27kDa protein 1 1.08584
CA2 carbonic anhydrase II 1.08407
PRKCB protein kinase C, beta 1.08407
STMN1 stathmin 1 1.08407
CALM1 calmodulin 1 (phosphorylase kinase, delta) 1.08407
SLC30A1 solute carrier family 30 (zinc transporter), member 1 1.08091
SMAD3 SMAD family member 3 1.07947
APAF1 apoptotic peptidase activating factor 1 1.07947
NCF2 neutrophil cytosolic factor 2 1.07768
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled 1.07768
CSF1 colony stimulating factor 1 (macrophage) 1.07768
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha 1.07589
PSAT1 phosphoserine aminotransferase 1 1.07447
ALOX5 arachidonate 5-lipoxygenase 1.07411
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 1.07199
GAP43 growth associated protein 43 1.07128
HSD17B4 hydroxysteroid (17-beta) dehydrogenase 4 1.07128
CHUK conserved helix-loop-helix ubiquitous kinase 1.06987
SRM spermidine synthase 1.06952
C10ORF10 chromosome 10 open reading frame 10 1.06952
GUCY1B3 guanylate cyclase 1, soluble, beta 3 1.06952
IRAK1 interleukin-1 receptor-associated kinase 1 1.06952
FBLN1 fibulin 1 1.06952
PTGES prostaglandin E synthase 1.06808
FST follistatin 1.06808
APOB apolipoprotein B 1.06734
CCL4 chemokine (C-C motif) ligand 4 1.06661
TRIM28 tripartite motif containing 28 1.06515
WIPI1 WD repeat domain, phosphoinositide interacting 1 1.06515
GRB7 growth factor receptor-bound protein 7 1.06515
WARS tryptophanyl-tRNA synthetase 1.06479
FABP1 fatty acid binding protein 1, liver 1.06479
ACO2 aconitase 2, mitochondrial 1.06479
CCNG1 cyclin G1 1.06479
ACTG2 actin, gamma 2, smooth muscle, enteric 1.06479
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1 1.0608
AGAP3 ArfGAP with GTPase domain, ankyrin repeat and PH domain 3 1.06044
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3 1.06044
TBX21 T-box 21 1.05864
PLTP phospholipid transfer protein 1.05648
CYR61 cysteine-rich, angiogenic inducer, 61 1.05535
IRS1 insulin receptor substrate 1 1.05535
GEM GTP binding protein overexpressed in skeletal muscle 1.052
ANXA1 annexin A1 1.05089
IL3 interleukin 3 1.04794
TEK TEK tyrosine kinase, endothelial 1.04794
HTRA1 HtrA serine peptidase 1 1.04757
S100A4 S100 calcium binding protein A4 1.04647
EPAS1 endothelial PAS domain protein 1 1.04647
COLEC12 collectin sub-family member 12 1.04538
PPP1R2 protein phosphatase 1, regulatory (inhibitor) subunit 2 1.04538
TRIM63 tripartite motif containing 63, E3 ubiquitin protein ligase 1.04538
SMAD2 SMAD family member 2 1.04352
CKB creatine kinase, brain 1.04352
GAD1 glutamate decarboxylase 1 (brain, 67kDa) 1.04051
LIF leukemia inhibitory factor 1.04051
TNNI3 troponin I type 3 (cardiac) 1.03939
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2 1.03939
RFC3 replication factor C (activator 1) 3, 38kDa 1.03939
SARS seryl-tRNA synthetase 1.03901
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F 1.03789
HBB hemoglobin, beta 1.03752
G0S2 G0/G1 switch 2 1.03752
ERP29 endoplasmic reticulum protein 29 1.0353
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor 1.03493
CDC6 cell division cycle 6 1.03456
JUNB jun B proto-oncogene 1.03345
SOCS3 suppressor of cytokine signaling 3 1.03271
GPLD1 glycosylphosphatidylinositol specific phospholipase D1 1.03271
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1 1.02971
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 1.02858
APOA1 apolipoprotein A-I 1.02821
TDG thymine-DNA glycosylase 1.02708
PF4 platelet factor 4 1.02708
MMP10 matrix metallopeptidase 10 1.02708
VASP vasodilator-stimulated phosphoprotein 1.02336
ADIPOR2 adiponectin receptor 2 1.02336
MCM6 minichromosome maintenance complex component 6 1.02299
FDPS farnesyl diphosphate synthase 1.02299
FKBP1B FK506 binding protein 1B, 12.6 kDa 1.02114
FOXP3 forkhead box P3 1.02114
FZD5 frizzled class receptor 5 1.02077
KCTD12 potassium channel tetramerization domain containing 12 1.02077
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa 1.0204
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 1.0204
THRA thyroid hormone receptor, alpha 1.0204
CYP3A7 cytochrome P450, family 3, subfamily A, polypeptide 7 1.01966
HSPE1 heat shock 10kDa protein 1 1.01739
A2M alpha-2-macroglobulin 1.01739
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 1.01739
EGR3 early growth response 3 1.01549
CRY1 cryptochrome circadian clock 1 1.01512
RHOB ras homolog family member B 1.01174
CHEK1 checkpoint kinase 1 1.01099