Angiogenesis Gene Set

Dataset PANTHER Pathways
Category structural or functional annotations
Type pathway
Description Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels. (Gene Ontology, GO_0001525)
External Link http://www.pantherdb.org/pathway/pathDetail.do?clsAccession=P00005
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Genes

141 proteins participating in the Angiogenesis pathway from the PANTHER Pathways dataset.

Symbol Name
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT2 v-akt murine thymoma viral oncogene homolog 2
AKT3 v-akt murine thymoma viral oncogene homolog 3
ANGPT1 angiopoietin 1
ANGPT2 angiopoietin 2
APC adenomatous polyposis coli
APC2 adenomatosis polyposis coli 2
ARAF A-Raf proto-oncogene, serine/threonine kinase
ARHGAP1 Rho GTPase activating protein 1
ARHGAP8 Rho GTPase activating protein 8
AXIN1 axin 1
BAD BCL2-associated agonist of cell death
BIRC5 baculoviral IAP repeat containing 5
BRAF B-Raf proto-oncogene, serine/threonine kinase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
DLK1 delta-like 1 homolog (Drosophila)
DLL1 delta-like 1 (Drosophila)
DLL3 delta-like 3 (Drosophila)
DLL4 delta-like 4 (Drosophila)
DOK2 docking protein 2, 56kDa
DVL1 dishevelled segment polarity protein 1
DVL2 dishevelled segment polarity protein 2
DVL3 dishevelled segment polarity protein 3
EFNB1 ephrin-B1
EFNB2 ephrin-B2
EPHB1 EPH receptor B1
EPHB2 EPH receptor B2
EPHB3 EPH receptor B3
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
F2R coagulation factor II (thrombin) receptor
F3 coagulation factor III (thromboplastin, tissue factor)
F7 coagulation factor VII (serum prothrombin conversion accelerator)
FGF1 fibroblast growth factor 1 (acidic)
FGFR1 fibroblast growth factor receptor 1
FOS FBJ murine osteosarcoma viral oncogene homolog
FRS2 fibroblast growth factor receptor substrate 2
FZD1 frizzled class receptor 1
FZD2 frizzled class receptor 2
FZD3 frizzled class receptor 3
FZD5 frizzled class receptor 5
GRB14 growth factor receptor-bound protein 14
GRB7 growth factor receptor-bound protein 7
GSK3B glycogen synthase kinase 3 beta
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HRAS Harvey rat sarcoma viral oncogene homolog
HSPB1 heat shock 27kDa protein 1
JAG1 jagged 1
JAG2 jagged 2
JAK1 Janus kinase 1
JUN jun proto-oncogene
KDR kinase insert domain receptor
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K2 mitogen-activated protein kinase kinase 2
MAP2K4 mitogen-activated protein kinase kinase 4
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3
NCK1 NCK adaptor protein 1
NCK2 NCK adaptor protein 2
NOS3 nitric oxide synthase 3 (endothelial cell)
NOTCH1 notch 1
NOTCH2 notch 2
NOTCH4 notch 4
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PDGFA platelet-derived growth factor alpha polypeptide
PDGFB platelet-derived growth factor beta polypeptide
PDGFC platelet derived growth factor C
PDGFD platelet derived growth factor D
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PLA2G4D phospholipase A2, group IVD (cytosolic)
PLCG1 phospholipase C, gamma 1
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLD1 phospholipase D1, phosphatidylcholine-specific
PLD2 phospholipase D2
PRKCA protein kinase C, alpha
PRKCB protein kinase C, beta
PRKCD protein kinase C, delta
PRKCE protein kinase C, epsilon
PRKCG protein kinase C, gamma
PRKCH protein kinase C, eta
PRKCI protein kinase C, iota
PRKCQ protein kinase C, theta
PRKCZ protein kinase C, zeta
PRKD1 protein kinase D1
PRKD2 protein kinase D2
PRKD3 protein kinase D3
PTK2 protein tyrosine kinase 2
PTPRB protein tyrosine phosphatase, receptor type, B
PXN paxillin
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RASA1 RAS p21 protein activator (GTPase activating protein) 1
RBPJ recombination signal binding protein for immunoglobulin kappa J region
RBPJL recombination signal binding protein for immunoglobulin kappa J region-like
RHOA ras homolog family member A
RHOB ras homolog family member B
RHOC ras homolog family member C
SH2D2A SH2 domain containing 2A
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SHC2 SHC (Src homology 2 domain containing) transforming protein 2
SOS1 son of sevenless homolog 1 (Drosophila)
SPHK1 sphingosine kinase 1
SPHK2 sphingosine kinase 2
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
TCF7 transcription factor 7 (T-cell specific, HMG-box)
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TEK TEK tyrosine kinase, endothelial
VEGFA vascular endothelial growth factor A
WNT1 wingless-type MMTV integration site family, member 1
WNT10A wingless-type MMTV integration site family, member 10A
WNT10B wingless-type MMTV integration site family, member 10B
WNT2 wingless-type MMTV integration site family member 2
WNT2B wingless-type MMTV integration site family, member 2B
WNT5A wingless-type MMTV integration site family, member 5A
WNT5B wingless-type MMTV integration site family, member 5B
WNT7A wingless-type MMTV integration site family, member 7A
WNT7B wingless-type MMTV integration site family, member 7B