Angiogenesis Gene Set

Dataset WikiPathways Pathways 2024
Category structural or functional annotations
Type pathway
Description Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels. (Gene Ontology, GO_0001525)
External Link https://www.wikipathways.org/pathways/WP1539.html
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Genes

24 proteins participating in the Angiogenesis pathway from the WikiPathways Pathways 2024 dataset.

Symbol Name
AKT1 v-akt murine thymoma viral oncogene homolog 1
ANGPT1 angiopoietin 1
ARNT aryl hydrocarbon receptor nuclear translocator
CREBBP CREB binding protein
FGF2 fibroblast growth factor 2 (basic)
FGFR2 fibroblast growth factor receptor 2
FLT1 fms-related tyrosine kinase 1
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
KDR kinase insert domain receptor
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MMP9 matrix metallopeptidase 9
NOS3 nitric oxide synthase 3 (endothelial cell)
PDGFB platelet-derived growth factor beta polypeptide
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PLCG1 phospholipase C, gamma 1
PTK2 protein tyrosine kinase 2
SMAD1 SMAD family member 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
TEK TEK tyrosine kinase, endothelial
TIMP2 TIMP metallopeptidase inhibitor 2
TIMP3 TIMP metallopeptidase inhibitor 3
VEGFA vascular endothelial growth factor A