Anhedonia Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description Inability to experience pleasure activities usually found enjoyable. (Human Phenotype Ontology, HP_0012154)
External Link https://www.disgenet.org/browser/0/1/0/C0178417
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Genes

94 genes associated with the disease Anhedonia in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
AIF1 allograft inflammatory factor 1
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
APOE apolipoprotein E
ATF7IP activating transcription factor 7 interacting protein
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide
AVP arginine vasopressin
BDNF brain-derived neurotrophic factor
BICC1 BicC family RNA binding protein 1
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit
CCR6 chemokine (C-C motif) receptor 6
CCR7 chemokine (C-C motif) receptor 7
CDYL chromodomain protein, Y-like
CFP complement factor properdin
CHPT1 choline phosphotransferase 1
CHRNB4 cholinergic receptor, nicotinic, beta 4 (neuronal)
CIT citron rho-interacting serine/threonine kinase
CNR1 cannabinoid receptor 1 (brain)
COMT catechol-O-methyltransferase
CPT1A carnitine palmitoyltransferase 1A (liver)
CPT2 carnitine palmitoyltransferase 2
CRH corticotropin releasing hormone
CRHR1 corticotropin releasing hormone receptor 1
CRHR2 corticotropin releasing hormone receptor 2
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CX3CR1 chemokine (C-X3-C motif) receptor 1
DHDDS dehydrodolichyl diphosphate synthase
DISC1 disrupted in schizophrenia 1
DPP4 dipeptidyl-peptidase 4
DPT dermatopontin
DRD2 dopamine receptor D2
FADD Fas (TNFRSF6)-associated via death domain
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GAL galanin/GMAP prepropeptide
GBP5 guanylate binding protein 5
GJA1 gap junction protein, alpha 1, 43kDa
GORASP1 golgi reassembly stacking protein 1, 65kDa
GRIA1 glutamate receptor, ionotropic, AMPA 1
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B
GRIN2D glutamate receptor, ionotropic, N-methyl D-aspartate 2D
HCRT hypocretin (orexin) neuropeptide precursor
HOMER1 homer scaffolding protein 1
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
IDO1 indoleamine 2,3-dioxygenase 1
IDO2 indoleamine 2,3-dioxygenase 2
IDS iduronate 2-sulfatase
IL17A interleukin 17A
IL1B interleukin 1, beta
IL6 interleukin 6
KCNK2 potassium channel, two pore domain subfamily K, member 2
KEAP1 kelch-like ECH-associated protein 1
KRT7 keratin 7, type II
LAMC2 laminin, gamma 2
LEP leptin
LPA lipoprotein, Lp(a)
LRP2 low density lipoprotein receptor-related protein 2
MAPK1 mitogen-activated protein kinase 1
MBNL1 muscleblind-like splicing regulator 1
MC4R melanocortin 4 receptor
MCF2L MCF.2 cell line derived transforming sequence-like
NFE2L2 nuclear factor, erythroid 2-like 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
OPRK1 opioid receptor, kappa 1
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
P4HB prolyl 4-hydroxylase, beta polypeptide
PADI1 peptidyl arginine deiminase, type I
PDE4A phosphodiesterase 4A, cAMP-specific
PDIA2 protein disulfide isomerase family A, member 2
PDYN prodynorphin
PENK proenkephalin
PINK1 PTEN induced putative kinase 1
PITX3 paired-like homeodomain 3
POMC proopiomelanocortin
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PRL prolactin
PVALB parvalbumin
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
SAT1 spermidine/spermine N1-acetyltransferase 1
SCLY selenocysteine lyase
SETDB1 SET domain, bifurcated 1
SIRT1 sirtuin 1
SIRT2 sirtuin 2
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1
SYT1 synaptotagmin I
TAL1 T-cell acute lymphocytic leukemia 1
TLR4 toll-like receptor 4
TNF tumor necrosis factor
TPH2 tryptophan hydroxylase 2
WNK1 WNK lysine deficient protein kinase 1