Anorexia Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A lack or loss of appetite for food (as a medical condition). (Human Phenotype Ontology, HP_0002039)
External Link https://www.disgenet.org/browser/0/1/0/C0497397
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Genes

386 genes associated with the disease Anorexia in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABAT 4-aminobutyrate aminotransferase
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ACACA acetyl-CoA carboxylase alpha
ACAT1 acetyl-CoA acetyltransferase 1
ADIPOQ adiponectin, C1Q and collagen domain containing
ADIPOR2 adiponectin receptor 2
ADM adrenomedullin
AGRP agouti related neuropeptide
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)
AIMP2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
AKAP6 A kinase (PRKA) anchor protein 6
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALB albumin
ALPL alkaline phosphatase, liver/bone/kidney
AMY1A amylase, alpha 1A (salivary)
AMY1B amylase, alpha 1B (salivary)
AMY1C amylase, alpha 1C (salivary)
ANGPTL3 angiopoietin-like 3
ANGPTL4 angiopoietin-like 4
ANGPTL6 angiopoietin-like 6
APOB apolipoprotein B
AQP2 aquaporin 2 (collecting duct)
ARC activity-regulated cytoskeleton-associated protein
ARG1 arginase 1
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ASB3 ankyrin repeat and SOCS box containing 3
ATM ATM serine/threonine kinase
ATP8A2 ATPase, aminophospholipid transporter, class I, type 8A, member 2
ATRX alpha thalassemia/mental retardation syndrome X-linked
AVP arginine vasopressin
AVPR2 arginine vasopressin receptor 2
BCHE butyrylcholinesterase
BCOR BCL6 corepressor
BDNF brain-derived neurotrophic factor
BEST1 bestrophin 1
BMS1 BMS1 ribosome biogenesis factor
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
C1QL1 complement component 1, q subcomponent-like 1
C4A complement component 4A (Rodgers blood group)
C9ORF72 chromosome 9 open reading frame 72
CADM1 cell adhesion molecule 1
CALCA calcitonin-related polypeptide alpha
CALR calreticulin
CARD16 caspase recruitment domain family, member 16
CARF calcium responsive transcription factor
CARMIL1 capping protein regulator and myosin 1 linker 1
CARTPT CART prepropeptide
CBS cystathionine-beta-synthase
CCK cholecystokinin
CCKAR cholecystokinin A receptor
CCL28 chemokine (C-C motif) ligand 28
CCND1 cyclin D1
CCNE1 cyclin E1
CCR1 chemokine (C-C motif) receptor 1
CD200R1 CD200 receptor 1
CD247 CD247 molecule
CD38 CD38 molecule
CD3D CD3d molecule, delta (CD3-TCR complex)
CD3E CD3e molecule, epsilon (CD3-TCR complex)
CDAN1 codanin 1
CDH9 cadherin 9, type 2 (T1-cadherin)
CDKN2A cyclin-dependent kinase inhibitor 2A
CEP70 centrosomal protein 70kDa
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CGA glycoprotein hormones, alpha polypeptide
CGB chorionic gonadotropin, beta polypeptide
CGB5 chorionic gonadotropin, beta polypeptide 5
CGB8 chorionic gonadotropin, beta polypeptide 8
CHPT1 choline phosphotransferase 1
CLOCK clock circadian regulator
CNR1 cannabinoid receptor 1 (brain)
CNTN4 contactin 4
CNTN5 contactin 5
CNTN6 contactin 6
COMT catechol-O-methyltransferase
COX1
COX2
COX3
CPN1 carboxypeptidase N, polypeptide 1
CPN2 carboxypeptidase N, polypeptide 2
CRH corticotropin releasing hormone
CRHR1 corticotropin releasing hormone receptor 1
CRHR2 corticotropin releasing hormone receptor 2
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CRP C-reactive protein, pentraxin-related
CRYGD crystallin, gamma D
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CTBP2 C-terminal binding protein 2
CTRC chymotrypsin C (caldecrin)
CX3CL1 chemokine (C-X3-C motif) ligand 1
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6
DAXX death-domain associated protein
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase)
DBI diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)
DHDDS dehydrodolichyl diphosphate synthase
DLL1 delta-like 1 (Drosophila)
DMD dystrophin
DNTT DNA nucleotidylexotransferase
DPP4 dipeptidyl-peptidase 4
DRD2 dopamine receptor D2
DRD3 dopamine receptor D3
DRD4 dopamine receptor D4
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EBF1 early B-cell factor 1
EGFR epidermal growth factor receptor
EHMT1 euchromatic histone-lysine N-methyltransferase 1
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2)
EPHB1 EPH receptor B1
EPHB2 EPH receptor B2
EPHX2 epoxide hydrolase 2, cytoplasmic
EPO erythropoietin
ERAP1 endoplasmic reticulum aminopeptidase 1
ERLEC1 endoplasmic reticulum lectin 1
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
ETFA electron-transfer-flavoprotein, alpha polypeptide
FAAH fatty acid amide hydrolase
FAM19A2 family with sequence similarity 19 (chemokine (C-C motif)-like), member A2
FAS Fas cell surface death receptor
FASN fatty acid synthase
FBN1 fibrillin 1
FGF21 fibroblast growth factor 21
FIP1L1 factor interacting with PAPOLA and CPSF1
FLI1 Fli-1 proto-oncogene, ETS transcription factor
FOXP1 forkhead box P1
FTO fat mass and obesity associated
GAL galanin/GMAP prepropeptide
GBA glucosidase, beta, acid
GCG glucagon
GDF11 growth differentiation factor 11
GDF15 growth differentiation factor 15
GFAP glial fibrillary acidic protein
GFER growth factor, augmenter of liver regeneration
GFRAL GDNF family receptor alpha like
GHRL ghrelin/obestatin prepropeptide
GHSR growth hormone secretagogue receptor
GIP gastric inhibitory polypeptide
GJA1 gap junction protein, alpha 1, 43kDa
GLA galactosidase, alpha
GLI2 GLI family zinc finger 2
GLP1R glucagon-like peptide 1 receptor
GOLGA6A golgin A6 family, member A
GPR55 G protein-coupled receptor 55
GPR88 G protein-coupled receptor 88
GPT glutamic-pyruvate transaminase (alanine aminotransferase)
GRAP2 GRB2-related adaptor protein 2
GRHL3 grainyhead-like 3 (Drosophila)
GRIA3 glutamate receptor, ionotropic, AMPA 3
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B
H2AX H2A.X variant histone
HCRT hypocretin (orexin) neuropeptide precursor
HCRTR2 hypocretin (orexin) receptor 2
HDAC4 histone deacetylase 4
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLA-B major histocompatibility complex, class I, B
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
HMBS hydroxymethylbilane synthase
HMGB1 high mobility group box 1
HMGCL 3-hydroxymethyl-3-methylglutaryl-CoA lyase
HPGDS hematopoietic prostaglandin D synthase
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
HTR1D 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
HTR2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
HTR3B 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
IFNA2 interferon, alpha 2
IFNG interferon, gamma
IFNGR1 interferon gamma receptor 1
IGF1 insulin-like growth factor 1 (somatomedin C)
IGFBP1 insulin-like growth factor binding protein 1
IGH immunoglobulin heavy locus
IK IK cytokine, down-regulator of HLA II
IL10 interleukin 10
IL12A interleukin 12A
IL12B interleukin 12B
IL15 interleukin 15
IL18 interleukin 18
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1RN interleukin 1 receptor antagonist
IL2 interleukin 2
IL23R interleukin 23 receptor
IL6 interleukin 6
IL6ST interleukin 6 signal transducer
INHBB inhibin, beta B
INSL5 insulin-like 5
IRF2BP2 interferon regulatory factor 2 binding protein 2
JAK2 Janus kinase 2
KCNN3 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3
KDR kinase insert domain receptor
KLRC4 killer cell lectin-like receptor subfamily C, member 4
KRAS Kirsten rat sarcoma viral oncogene homolog
KRT7 keratin 7, type II
LDLR low density lipoprotein receptor
LEP leptin
LEPR leptin receptor
LRIT1 leucine-rich repeat, immunoglobulin-like and transmembrane domains 1
LTB lymphotoxin beta (TNF superfamily, member 3)
LYZ lysozyme
MAGEL2 melanoma antigen family L2
MAOA monoamine oxidase A
MAPK1 mitogen-activated protein kinase 1
MAPK10 mitogen-activated protein kinase 10
MAPK14 mitogen-activated protein kinase 14
MBOAT4 membrane bound O-acyltransferase domain containing 4
MBP myelin basic protein
MC2R melanocortin 2 receptor (adrenocorticotropic hormone)
MC3R melanocortin 3 receptor
MC4R melanocortin 4 receptor
MCL1 myeloid cell leukemia 1
MDK midkine (neurite growth-promoting factor 2)
MECP2 methyl CpG binding protein 2
MEFV Mediterranean fever
MGMT O-6-methylguanine-DNA methyltransferase
MLN motilin
MLX MLX, MAX dimerization protein
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
MMADHC methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria
MMP9 matrix metallopeptidase 9
MMUT methylmalonyl-CoA mutase
MNAT1 MNAT CDK-activating kinase assembly factor 1
MPL MPL proto-oncogene, thrombopoietin receptor
MRAP melanocortin 2 receptor accessory protein
MSTN myostatin
MT-ND4 NADH dehydrogenase, subunit 4 (complex I)
MT-ND5 NADH dehydrogenase, subunit 5 (complex I)
MT-ND6 NADH dehydrogenase, subunit 6 (complex I)
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MUC1 mucin 1, cell surface associated
MYD88 myeloid differentiation primary response 88
NABP1 nucleic acid binding protein 1
NBEAL1 neurobeachin-like 1
NCKIPSD NCK interacting protein with SH3 domain
NCOA6 nuclear receptor coactivator 6
ND1
NEFL neurofilament, light polypeptide
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
NIPA1 non imprinted in Prader-Willi/Angelman syndrome 1
NMU neuromedin U
NMUR2 neuromedin U receptor 2
NNAT neuronatin
NNT nicotinamide nucleotide transhydrogenase
NPB neuropeptide B
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NPPB natriuretic peptide B
NPSR1 neuropeptide S receptor 1
NPW neuropeptide W
NPY neuropeptide Y
NPY1R neuropeptide Y receptor Y1
NPY2R neuropeptide Y receptor Y2
NR1H3 nuclear receptor subfamily 1, group H, member 3
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NT5C1B 5'-nucleotidase, cytosolic IB
NTNG1 netrin G1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
NTRK3 neurotrophic tyrosine kinase, receptor, type 3
NTSR1 neurotensin receptor 1 (high affinity)
NUCB1 nucleobindin 1
NUCB2 nucleobindin 2
NUMA1 nuclear mitotic apparatus protein 1
OGN osteoglycin
OLIG2 oligodendrocyte lineage transcription factor 2
OPN1SW opsin 1 (cone pigments), short-wave-sensitive
OPRD1 opioid receptor, delta 1
OPRL1 opiate receptor-like 1
OPRM1 opioid receptor, mu 1
OR2AG1 olfactory receptor, family 2, subfamily AG, member 1 (gene/pseudogene)
OXT oxytocin/neurophysin I prepropeptide
OXTR oxytocin receptor
PALB2 partner and localizer of BRCA2
PALLD palladin, cytoskeletal associated protein
PAM peptidylglycine alpha-amidating monooxygenase
PANK2 pantothenate kinase 2
PARP9 poly (ADP-ribose) polymerase family, member 9
PDE3B phosphodiesterase 3B, cGMP-inhibited
PDLIM7 PDZ and LIM domain 7 (enigma)
PEPB peptidase B
PGC progastricsin (pepsinogen C)
PLCL1 phospholipase C-like 1
PML promyelocytic leukemia
POLDIP2 polymerase (DNA-directed), delta interacting protein 2
POMC proopiomelanocortin
POSTN periostin, osteoblast specific factor
PPIG peptidylprolyl isomerase G (cyclophilin G)
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PRL prolactin
PRNP prion protein
PRSS1 protease, serine, 1 (trypsin 1)
PSMB6 proteasome (prosome, macropain) subunit, beta type, 6
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTGES prostaglandin E synthase
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTH parathyroid hormone
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
PTPN3 protein tyrosine phosphatase, non-receptor type 3
PYY peptide YY
RAN RAN, member RAS oncogene family
RARA retinoic acid receptor, alpha
RCBTB1 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
RETN resistin
RMC1 regulator of MON1-CCZ1
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RPS19 ribosomal protein S19
RSPO1 R-spondin 1
S100B S100 calcium binding protein B
SCARB2 scavenger receptor class B, member 2
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCLY selenocysteine lyase
SDS serine dehydratase
SETD2 SET domain containing 2
SGSH N-sulfoglucosamine sulfohydrolase
SHBG sex hormone-binding globulin
SHCBP1 SHC SH2-domain binding protein 1
SIRT1 sirtuin 1
SLC18A1 solute carrier family 18 (vesicular monoamine transporter), member 1
SLC19A2 solute carrier family 19 (thiamine transporter), member 2
SLC39A4 solute carrier family 39 (zinc transporter), member 4
SLC46A1 solute carrier family 46 (folate transporter), member 1
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group)
SLC5A1 solute carrier family 5 (sodium/glucose cotransporter), member 1
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SMAD4 SMAD family member 4
SMIM20 small integral membrane protein 20
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SORCS2 sortilin-related VPS10 domain containing receptor 2
SPAG9 sperm associated antigen 9
SPINK1 serine peptidase inhibitor, Kazal type 1
SPX spexin hormone
SS18L1 synovial sarcoma translocation gene on chromosome 18-like 1
SST somatostatin
STAR steroidogenic acute regulatory protein
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT4 signal transducer and activator of transcription 4
STAT5B signal transducer and activator of transcription 5B
STATH statherin
STMN1 stathmin 1
SYTL5 synaptotagmin-like 5
TAC1 tachykinin, precursor 1
TACR1 tachykinin receptor 1
TAL1 T-cell acute lymphocytic leukemia 1
TAS2R38 taste receptor, type 2, member 38
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TET2 tet methylcytosine dioxygenase 2
TGFB1 transforming growth factor, beta 1
TLR4 toll-like receptor 4
TNF tumor necrosis factor
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNXB tenascin XB
TP53 tumor protein p53
TPH2 tryptophan hydroxylase 2
TREX1 three prime repair exonuclease 1
TXNRD2 thioredoxin reductase 2
UBAC2 UBA domain containing 2
UCN urocortin
UCN2 urocortin 2
UCN3 urocortin 3
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
UCP3 uncoupling protein 3 (mitochondrial, proton carrier)
UMOD uromodulin
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
VIP vasoactive intestinal peptide
WAS Wiskott-Aldrich syndrome
WDHD1 WD repeat and HMG-box DNA binding protein 1
YY1 YY1 transcription factor
ZBTB16 zinc finger and BTB domain containing 16
ZDHHC2 zinc finger, DHHC-type containing 2
ZGLP1 zinc finger, GATA-like protein 1
ZW10 zw10 kinetochore protein