Anovulation Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores 2025
Category disease or phenotype associations
Type disease
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Genes

313 genes co-occuring with the disease Anovulation in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.

Symbol Name Standardized Value
AMH anti-Mullerian hormone 3.547
SHBG sex hormone-binding globulin 3.465
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) 3.244
INS insulin 3.185
PRL prolactin 2.999
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1 2.891
KISS1 KiSS-1 metastasis-suppressor 2.876
LHCGR luteinizing hormone/choriogonadotropin receptor 2.839
FSHR follicle stimulating hormone receptor 2.769
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1 2.747
GDF9 growth differentiation factor 9 2.712
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1 2.699
DENND1A DENN/MADD domain containing 1A 2.694
BMP15 bone morphogenetic protein 15 2.598
LEP leptin 2.565
IGF1 insulin-like growth factor 1 (somatomedin C) 2.496
INSR insulin receptor 2.492
ESR1 estrogen receptor 1 2.482
STAR steroidogenic acute regulatory protein 2.458
FSHB follicle stimulating hormone, beta polypeptide 2.381
AMHR2 anti-Mullerian hormone receptor, type II 2.372
ADIPOQ adiponectin, C1Q and collagen domain containing 2.358
POMC proopiomelanocortin 2.343
TAC3 tachykinin 3 2.329
HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 2.32
ESR2 estrogen receptor 2 (ER beta) 2.283
AR androgen receptor 2.268
IGFBP1 insulin-like growth factor binding protein 1 2.267
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 2.217
PGR progesterone receptor 2.203
GNRHR gonadotropin-releasing hormone receptor 2.194
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4 2.145
FBN3 fibrillin 3 2.121
KISS1R KISS1 receptor 2.097
IRS1 insulin receptor substrate 1 2.093
AOPEP aminopeptidase O (putative) 2.085
IL6 interleukin 6 2.02
RAB5B RAB5B, member RAS oncogene family 2.009
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1 1.964
THADA thyroid adenoma associated 1.956
PDYN prodynorphin 1.956
DHRS11 dehydrogenase/reductase (SDR family) member 11 1.95
FST follistatin 1.943
FOXL2 forkhead box L2 1.942
CYP21A2 cytochrome P450, family 21, subfamily A, polypeptide 2 1.936
TNF tumor necrosis factor 1.923
CRP C-reactive protein, pentraxin-related 1.919
GHRL ghrelin/obestatin prepropeptide 1.904
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.899
PPARG peroxisome proliferator-activated receptor gamma 1.896
TACR3 tachykinin receptor 3 1.895
CAPN10 calpain 10 1.893
RETN resistin 1.884
HOXA10 homeobox A10 1.883
RHCG Rh family, C glycoprotein 1.88
AKR1C3 aldo-keto reductase family 1, member C3 1.868
NR5A1 nuclear receptor subfamily 5, group A, member 1 1.862
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 1.854
RETNLB resistin like beta 1.853
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 1.828
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 1.825
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta 1.822
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta 1.821
TRH thyrotropin-releasing hormone 1.809
NOBOX NOBOX oogenesis homeobox 1.789
INSL3 insulin-like 3 (Leydig cell) 1.785
ALB albumin 1.776
IL1B interleukin 1, beta 1.775
NPY neuropeptide Y 1.765
TOX3 TOX high mobility group box family member 3 1.765
TGFB1 transforming growth factor, beta 1 1.757
PAEP progestagen-associated endometrial protein 1.743
FOXO3 forkhead box O3 1.73
NAMPT nicotinamide phosphoribosyltransferase 1.719
GAPDH glyceraldehyde-3-phosphate dehydrogenase 1.717
CRH corticotropin releasing hormone 1.716
OXT oxytocin/neurophysin I prepropeptide 1.704
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1.702
GCG glucagon 1.695
ZP3 zona pellucida glycoprotein 3 (sperm receptor) 1.694
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 1.686
FOXO1 forkhead box O1 1.682
NPVF neuropeptide VF precursor 1.681
NPR2 natriuretic peptide receptor 2 1.668
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 1.666
IRS2 insulin receptor substrate 2 1.663
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 1.661
FIGLA folliculogenesis specific basic helix-loop-helix 1.66
ACTB actin, beta 1.653
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3 1.644
FNDC5 fibronectin type III domain containing 5 1.637
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6 1.619
GJA4 gap junction protein, alpha 4, 37kDa 1.618
IL18 interleukin 18 1.616
PTEN phosphatase and tensin homolog 1.615
RARRES2 retinoic acid receptor responder (tazarotene induced) 2 1.608
SLCO2A1 solute carrier organic anion transporter family, member 2A1 1.605
PRLR prolactin receptor 1.604
GPER1 G protein-coupled estrogen receptor 1 1.599
LEPR leptin receptor 1.582
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) 1.579
IGF2 insulin-like growth factor 2 1.575
IL1A interleukin 1, alpha 1.553
NPPC natriuretic peptide C 1.552
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.532
NGF nerve growth factor (beta polypeptide) 1.522
PXDN peroxidasin 1.517
PXDNL peroxidasin-like 1.515
ZP1 zona pellucida glycoprotein 1 (sperm receptor) 1.505
AGRP agouti related neuropeptide 1.505
BMPR1B bone morphogenetic protein receptor, type IB 1.504
IGF1R insulin-like growth factor 1 receptor 1.502
MAPK3 mitogen-activated protein kinase 3 1.499
GLP1R glucagon-like peptide 1 receptor 1.496
ZP4 zona pellucida glycoprotein 4 1.495
INHBB inhibin, beta B 1.495
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 1.489
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.483
GPX3 glutathione peroxidase 3 1.479
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2 1.476
MC4R melanocortin 4 receptor 1.475
PRKACG protein kinase, cAMP-dependent, catalytic, gamma 1.469
HSD17B3 hydroxysteroid (17-beta) dehydrogenase 3 1.468
KRR1 KRR1, small subunit (SSU) processome component, homolog (yeast) 1.465
SIRT1 sirtuin 1 1.464
MTNR1A melatonin receptor 1A 1.463
EGF epidermal growth factor 1.463
BCL2 B-cell CLL/lymphoma 2 1.462
KITLG KIT ligand 1.46
FOS FBJ murine osteosarcoma viral oncogene homolog 1.46
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 1.458
NR5A2 nuclear receptor subfamily 5, group A, member 2 1.457
PRKACB protein kinase, cAMP-dependent, catalytic, beta 1.453
PRKACA protein kinase, cAMP-dependent, catalytic, alpha 1.45
CCL2 chemokine (C-C motif) ligand 2 1.447
WNT4 wingless-type MMTV integration site family, member 4 1.441
REN renin 1.438
SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) 1.433
PYY peptide YY 1.431
PGRMC1 progesterone receptor membrane component 1 1.428
GPX7 glutathione peroxidase 7 1.427
HMGA2 high mobility group AT-hook 2 1.427
BAX BCL2-associated X protein 1.423
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 1.423
GPX8 glutathione peroxidase 8 (putative) 1.417
GPX6 glutathione peroxidase 6 1.412
TP53 tumor protein p53 1.408
GPX5 glutathione peroxidase 5 1.405
TNFAIP6 tumor necrosis factor, alpha-induced protein 6 1.4
LIF leukemia inhibitory factor 1.399
EREG epiregulin 1.397
CYP11B1 cytochrome P450, family 11, subfamily B, polypeptide 1 1.397
GPX2 glutathione peroxidase 2 1.392
PLG plasminogen 1.39
AREG amphiregulin 1.386
FTO fat mass and obesity associated 1.382
APOB apolipoprotein B 1.38
CMKLR1 chemerin chemokine-like receptor 1 1.375
SUOX sulfite oxidase 1.374
YAP1 Yes-associated protein 1 1.372
TPO thyroid peroxidase 1.362
STRA8 stimulated by retinoic acid 8 1.357
CXCL8 chemokine (C-X-C motif) ligand 8 1.355
LBR lamin B receptor 1.349
CYB5A cytochrome b5 type A (microsomal) 1.349
HAS2 hyaluronan synthase 2 1.349
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) 1.342
PCNA proliferating cell nuclear antigen 1.34
SOHLH2 spermatogenesis and oogenesis specific basic helix-loop-helix 2 1.329
ADIPOR1 adiponectin receptor 1 1.327
TG thyroglobulin 1.313
SREBF1 sterol regulatory element binding transcription factor 1 1.306
GJA1 gap junction protein, alpha 1, 43kDa 1.306
MTNR1B melatonin receptor 1B 1.304
LHB luteinizing hormone beta polypeptide 1.304
INHBA inhibin, beta A 1.303
IGFBP3 insulin-like growth factor binding protein 3 1.287
ADIPOR2 adiponectin receptor 2 1.282
BMP6 bone morphogenetic protein 6 1.282
ITLN1 intelectin 1 (galactofuranose binding) 1.281
CREB1 cAMP responsive element binding protein 1 1.276
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 1.275
DAZL deleted in azoospermia-like 1.272
CCND2 cyclin D2 1.27
ZNF217 zinc finger protein 217 1.266
FGF2 fibroblast growth factor 2 (basic) 1.265
EDN1 endothelin 1 1.261
UCP1 uncoupling protein 1 (mitochondrial, proton carrier) 1.258
IL10 interleukin 10 1.257
SLC2A12 solute carrier family 2 (facilitated glucose transporter), member 12 1.243
GATA4 GATA binding protein 4 1.239
JUN jun proto-oncogene 1.238
PPARA peroxisome proliferator-activated receptor alpha 1.233
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.229
ZP2 zona pellucida glycoprotein 2 (sperm receptor) 1.228
PGRMC2 progesterone receptor membrane component 2 1.226
IFNG interferon, gamma 1.225
MMP9 matrix metallopeptidase 9 1.225
PON1 paraoxonase 1 1.223
DPP4 dipeptidyl-peptidase 4 1.218
FOXO4 forkhead box O4 1.218
APOA1 apolipoprotein A-I 1.214
SOHLH1 spermatogenesis and oogenesis specific basic helix-loop-helix 1 1.207
POR P450 (cytochrome) oxidoreductase 1.19
LPL lipoprotein lipase 1.19
TBC1D4 TBC1 domain family, member 4 1.186
EDN2 endothelin 2 1.183
USP34 ubiquitin specific peptidase 34 1.182
BDNF brain-derived neurotrophic factor 1.182
SYCP2L synaptonemal complex protein 2-like 1.182
LIPE lipase, hormone-sensitive 1.181
PABPN1L poly(A) binding protein, nuclear 1-like (cytoplasmic) 1.178
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.177
CCK cholecystokinin 1.175
UNK unkempt family zinc finger 1.172
ANOS1 anosmin 1 1.168
DDX4 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 1.166
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 1.165
SYCP3 synaptonemal complex protein 3 1.165
PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1 1.159
SCARB1 scavenger receptor class B, member 1 1.154
YBX2 Y box binding protein 2 1.154
FGF8 fibroblast growth factor 8 (androgen-induced) 1.153
SERPINA7 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 1.152
HP haptoglobin 1.151
CCDC169-SOHLH2 CCDC169-SOHLH2 readthrough 1.145
GH1 growth hormone 1 1.145
TLR4 toll-like receptor 4 1.141
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 1.14
NEIL2 nei endonuclease VIII-like 2 (E. coli) 1.139
POLE polymerase (DNA directed), epsilon, catalytic subunit 1.139
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.137
GATA6 GATA binding protein 6 1.136
SULT1E1 sulfotransferase family 1E, estrogen-preferring, member 1 1.131
BRCA1 breast cancer 1, early onset 1.129
ARL14EP ADP-ribosylation factor-like 14 effector protein 1.128
APLN apelin 1.124
CDCA4 cell division cycle associated 4 1.123
RPL19 ribosomal protein L19 1.121
RBP4 retinol binding protein 4, plasma 1.108
TFAM transcription factor A, mitochondrial 1.108
BMP4 bone morphogenetic protein 4 1.108
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1 1.105
CD4 CD4 molecule 1.103
CSH1 chorionic somatomammotropin hormone 1 (placental lactogen) 1.102
AHR aryl hydrocarbon receptor 1.1
CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2 1.097
SIRT3 sirtuin 3 1.095
CYCS cytochrome c, somatic 1.095
IHH indian hedgehog 1.095
FMR1 fragile X mental retardation 1 1.094
FEM1B fem-1 homolog b (C. elegans) 1.091
ASMT acetylserotonin O-methyltransferase 1.09
SERPINA12 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12 1.09
OXTR oxytocin receptor 1.088
PGF placental growth factor 1.086
FGF7 fibroblast growth factor 7 1.083
MADD MAP-kinase activating death domain 1.083
BMPR1A bone morphogenetic protein receptor, type IA 1.082
FGF18 fibroblast growth factor 18 1.082
PLGRKT plasminogen receptor, C-terminal lysine transmembrane protein 1.079
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 1.079
CSH2 chorionic somatomammotropin hormone 2 1.078
PTH parathyroid hormone 1.077
PTX3 pentraxin 3, long 1.075
NTSR1 neurotensin receptor 1 (high affinity) 1.075
FGF10 fibroblast growth factor 10 1.074
FGF9 fibroblast growth factor 9 1.073
SMAD5 SMAD family member 5 1.073
LIPC lipase, hepatic 1.072
ACE angiotensin I converting enzyme 1.07
GAL galanin/GMAP prepropeptide 1.07
AFM afamin 1.069
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 1.067
FGF4 fibroblast growth factor 4 1.067
FGF21 fibroblast growth factor 21 1.066
IL17A interleukin 17A 1.064
GC group-specific component (vitamin D binding protein) 1.063
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2 1.062
TRHDE thyrotropin-releasing hormone degrading enzyme 1.058
PPIG peptidylprolyl isomerase G (cyclophilin G) 1.057
FGF22 fibroblast growth factor 22 1.056
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 1.055
FOXO6 forkhead box O6 1.055
FGF6 fibroblast growth factor 6 1.055
GHRH growth hormone releasing hormone 1.052
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 1.05
FGF17 fibroblast growth factor 17 1.05
FGF5 fibroblast growth factor 5 1.047
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 1.045
ERBB4 erb-b2 receptor tyrosine kinase 4 1.043
FGF16 fibroblast growth factor 16 1.043
IL22 interleukin 22 1.041
FGF20 fibroblast growth factor 20 1.04
TH tyrosine hydroxylase 1.039
STON1-GTF2A1L STON1-GTF2A1L readthrough 1.038
IL2 interleukin 2 1.037
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 1.033
STK11 serine/threonine kinase 11 1.031
FGF3 fibroblast growth factor 3 1.029
SMAD2 SMAD family member 2 1.028
DPPA3 developmental pluripotency associated 3 1.027
GHR growth hormone receptor 1.024
LHX8 LIM homeobox 8 1.024
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 1.02
AKT2 v-akt murine thymoma viral oncogene homolog 2 1.015
DICER1 dicer 1, ribonuclease type III 1.013
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3 1.01
CGB5 chorionic gonadotropin, beta polypeptide 5 1.009
MLH1 mutL homolog 1 1.005
IL4 interleukin 4 1.004
CRHR1 corticotropin releasing hormone receptor 1 1.004
RXFP2 relaxin/insulin-like family peptide receptor 2 1.002