Aortic Aneurysm Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description An aortic disease that is characterized by an enlargement (dilation) of the aorta to greater than 1.5 times normal size. (Human Disease Ontology, DOID_3627)
External Link https://www.disgenet.org/browser/0/1/0/C0741160
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Genes

655 genes associated with the disease Aortic Aneurysm in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCC11 ATP-binding cassette, sub-family C (CFTR/MRP), member 11
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
ACCS 1-aminocyclopropane-1-carboxylate synthase homolog (Arabidopsis)(non-functional)
ACE angiotensin I converting enzyme
ACE2 angiotensin I converting enzyme 2
ACLY ATP citrate lyase
ACR acrosin
ACSS2 acyl-CoA synthetase short-chain family member 2
ACTA2 actin, alpha 2, smooth muscle, aorta
ACTB actin, beta
ACVRL1 activin A receptor type II-like 1
ADAM10 ADAM metallopeptidase domain 10
ADAM17 ADAM metallopeptidase domain 17
ADAM8 ADAM metallopeptidase domain 8
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif, 3
ADAMTS4 ADAM metallopeptidase with thrombospondin type 1 motif, 4
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
ADAMTS7 ADAM metallopeptidase with thrombospondin type 1 motif, 7
ADAMTS8 ADAM metallopeptidase with thrombospondin type 1 motif, 8
ADAR adenosine deaminase, RNA-specific
ADCY10 adenylate cyclase 10 (soluble)
ADIPOQ adiponectin, C1Q and collagen domain containing
ADM adrenomedullin
ADM2 adrenomedullin 2
ADRA2B adrenoceptor alpha 2B
ADRB2 adrenoceptor beta 2, surface
AEBP1 AE binding protein 1
AGER advanced glycosylation end product-specific receptor
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AGTR1 angiotensin II receptor, type 1
AGTR2 angiotensin II receptor, type 2
AHCY adenosylhomocysteinase
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)
AIM2 absent in melanoma 2
AIMP2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALDH18A1 aldehyde dehydrogenase 18 family, member A1
ALOX5 arachidonate 5-lipoxygenase
ALOX5AP arachidonate 5-lipoxygenase-activating protein
ANGPT1 angiopoietin 1
ANGPT2 angiopoietin 2
ANGPTL2 angiopoietin-like 2
ANKRD44 ankyrin repeat domain 44
ANXA2 annexin A2
AOC3 amine oxidase, copper containing 3
AP2A1 adaptor-related protein complex 2, alpha 1 subunit
APLN apelin
APOA1 apolipoprotein A-I
APOE apolipoprotein E
APOH apolipoprotein H (beta-2-glycoprotein I)
APRT adenine phosphoribosyltransferase
AQP1 aquaporin 1 (Colton blood group)
AR androgen receptor
ARF1 ADP-ribosylation factor 1
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
ARG1 arginase 1
ARHGAP18 Rho GTPase activating protein 18
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ARR3 arrestin 3, retinal (X-arrestin)
ARSA arylsulfatase A
ARSI arylsulfatase family, member I
ATG5 autophagy related 5
ATG7 autophagy related 7
ATM ATM serine/threonine kinase
ATP7A ATPase, Cu++ transporting, alpha polypeptide
AVP arginine vasopressin
BAK1 BCL2-antagonist/killer 1
BAX BCL2-associated X protein
BCL2 B-cell CLL/lymphoma 2
BCR breakpoint cluster region
BGN biglycan
BICD1 bicaudal D homolog 1 (Drosophila)
BLVRA biliverdin reductase A
BMP2 bone morphogenetic protein 2
BTBD8 BTB (POZ) domain containing 8
BTK Bruton agammaglobulinemia tyrosine kinase
C12ORF57 chromosome 12 open reading frame 57
C1ORF228 chromosome 1 open reading frame 228
C3 complement component 3
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
CARD8 caspase recruitment domain family, member 8
CASP1 caspase 1, apoptosis-related cysteine peptidase
CASP4 caspase 4, apoptosis-related cysteine peptidase
CASP5 caspase 5, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CASR calcium-sensing receptor
CAT catalase
CAV1 caveolin 1, caveolae protein, 22kDa
CCL11 chemokine (C-C motif) ligand 11
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
CCL2 chemokine (C-C motif) ligand 2
CCL20 chemokine (C-C motif) ligand 20
CCL4 chemokine (C-C motif) ligand 4
CCL4L1 chemokine (C-C motif) ligand 4-like 1
CCL4L2 chemokine (C-C motif) ligand 4-like 2
CCL8 chemokine (C-C motif) ligand 8
CCN2 cellular communication network factor 2
CCR2 chemokine (C-C motif) receptor 2
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CCR6 chemokine (C-C motif) receptor 6
CCR7 chemokine (C-C motif) receptor 7
CD14 CD14 molecule
CD19 CD19 molecule
CD1D CD1d molecule
CD22 CD22 molecule
CD28 CD28 molecule
CD36 CD36 molecule (thrombospondin receptor)
CD38 CD38 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD40LG CD40 ligand
CD44 CD44 molecule (Indian blood group)
CD59 CD59 molecule, complement regulatory protein
CD68 CD68 molecule
CD69 CD69 molecule
CD8A CD8a molecule
CDH5 cadherin 5, type 2 (vascular endothelium)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CETP cholesteryl ester transfer protein, plasma
CGA glycoprotein hormones, alpha polypeptide
CHDH choline dehydrogenase
CHRNG cholinergic receptor, nicotinic, gamma (muscle)
CMA1 chymase 1, mast cell
CNN2 calponin 2
CNTN3 contactin 3 (plasmacytoma associated)
COL18A1 collagen, type XVIII, alpha 1
COL1A1 collagen, type I, alpha 1
COL1A2 collagen, type I, alpha 2
COL3A1 collagen, type III, alpha 1
COL5A2 collagen, type V, alpha 2
COMP cartilage oligomeric matrix protein
COQ8B coenzyme Q8B
CORT cortistatin
COX1
COX2
COX3
CPB2 carboxypeptidase B2 (plasma)
CREBBP CREB binding protein
CRISP2 cysteine-rich secretory protein 2
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like
CRP C-reactive protein, pentraxin-related
CSF1 colony stimulating factor 1 (macrophage)
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CST3 cystatin C
CSTB cystatin B (stefin B)
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTSA cathepsin A
CTSB cathepsin B
CTSC cathepsin C
CTSH cathepsin H
CTSK cathepsin K
CTSL cathepsin L
CTSS cathepsin S
CX3CL1 chemokine (C-X3-C motif) ligand 1
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXADR coxsackie virus and adenovirus receptor
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL16 chemokine (C-X-C motif) ligand 16
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR1 chemokine (C-X-C motif) receptor 1
CXCR2 chemokine (C-X-C motif) receptor 2
CXCR4 chemokine (C-X-C motif) receptor 4
CXCR6 chemokine (C-X-C motif) receptor 6
CYBB cytochrome b-245, beta polypeptide
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2
CYSLTR1 cysteinyl leukotriene receptor 1
DAB2IP DAB2 interacting protein
DCN decorin
DCTN4 dynactin 4 (p62)
DDIT3 DNA-damage-inducible transcript 3
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial
DHFR dihydrofolate reductase
DHX40 DEAH (Asp-Glu-Ala-His) box polypeptide 40
DNASE1 deoxyribonuclease I
DNMT1 DNA (cytosine-5-)-methyltransferase 1
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DPP4 dipeptidyl-peptidase 4
DUOX1 dual oxidase 1
DUOX2 dual oxidase 2
DYM dymeclin
E2F4 E2F transcription factor 4, p107/p130-binding
EBI3 Epstein-Barr virus induced 3
EBNA1BP2 EBNA1 binding protein 2
EDN1 endothelin 1
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2
EFNA5 ephrin-A5
EGF epidermal growth factor
EGFR epidermal growth factor receptor
EGLN2 egl-9 family hypoxia-inducible factor 2
EGLN3 egl-9 family hypoxia-inducible factor 3
EGR1 early growth response 1
EHF ets homologous factor
EHMT1 euchromatic histone-lysine N-methyltransferase 1
EIF4E eukaryotic translation initiation factor 4E
ELANE elastase, neutrophil expressed
ELAVL2 ELAV like neuron-specific RNA binding protein 2
ELN elastin
EP300 E1A binding protein p300
ERBB2 erb-b2 receptor tyrosine kinase 2
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
ERMARD ER membrane-associated RNA degradation
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
F10 coagulation factor X
F3 coagulation factor III (thromboplastin, tissue factor)
FABP4 fatty acid binding protein 4, adipocyte
FAM3D family with sequence similarity 3, member D
FASLG Fas ligand (TNF superfamily, member 6)
FBLN2 fibulin 2
FBLN5 fibulin 5
FBN1 fibrillin 1
FBN2 fibrillin 2
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
FCGRT Fc fragment of IgG, receptor, transporter, alpha
FCN3 ficolin (collagen/fibrinogen domain containing) 3
FGF2 fibroblast growth factor 2 (basic)
FGF23 fibroblast growth factor 23
FLNA filamin A, alpha
FLNB filamin B, beta
FLT1 fms-related tyrosine kinase 1
FN1 fibronectin 1
FOS FBJ murine osteosarcoma viral oncogene homolog
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FOXE3 forkhead box E3
FOXO1 forkhead box O1
FOXO4 forkhead box O4
FOXP3 forkhead box P3
FSD1 fibronectin type III and SPRY domain containing 1
FSD1L fibronectin type III and SPRY domain containing 1-like
GAA glucosidase, alpha; acid
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GAPDH glyceraldehyde-3-phosphate dehydrogenase
GCG glucagon
GDF15 growth differentiation factor 15
GLI2 GLI family zinc finger 2
GLP1R glucagon-like peptide 1 receptor
GNG2 guanine nucleotide binding protein (G protein), gamma 2
GPT glutamic-pyruvate transaminase (alanine aminotransferase)
GPX4 glutathione peroxidase 4
GRAP2 GRB2-related adaptor protein 2
GTF2H1 general transcription factor IIH, polypeptide 1, 62kDa
GYPA glycophorin A (MNS blood group)
GYPB glycophorin B (MNS blood group)
GYPE glycophorin E (MNS blood group)
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
HBEGF heparin-binding EGF-like growth factor
HCAR2 hydroxycarboxylic acid receptor 2
HCST hematopoietic cell signal transducer
HDAC1 histone deacetylase 1
HDAC5 histone deacetylase 5
HES1 hes family bHLH transcription factor 1
HEY2 hes-related family bHLH transcription factor with YRPW motif 2
HGD homogentisate 1,2-dioxygenase
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-DOA major histocompatibility complex, class II, DO alpha
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-DRB3 major histocompatibility complex, class II, DR beta 3
HLA-G major histocompatibility complex, class I, G
HMGB1 high mobility group box 1
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMOX1 heme oxygenase 1
HNF4A hepatocyte nuclear factor 4, alpha
HP haptoglobin
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HPN hepsin
HPSE heparanase
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPD1 heat shock 60kDa protein 1 (chaperonin)
HSPG2 heparan sulfate proteoglycan 2
IARS1 isoleucyl-tRNA synthetase 1
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial
ICAM1 intercellular adhesion molecule 1
ICAM2 intercellular adhesion molecule 2
IFIH1 interferon induced with helicase C domain 1
IFNA1 interferon, alpha 1
IFNA13 interferon, alpha 13
IFNG interferon, gamma
IL10 interleukin 10
IL12B interleukin 12B
IL13 interleukin 13
IL17A interleukin 17A
IL17D interleukin 17D
IL18 interleukin 18
IL18R1 interleukin 18 receptor 1
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1R1 interleukin 1 receptor, type I
IL1RN interleukin 1 receptor antagonist
IL2 interleukin 2
IL23A interleukin 23, alpha subunit p19
IL27 interleukin 27
IL2RA interleukin 2 receptor, alpha
IL33 interleukin 33
IL4 interleukin 4
IL6 interleukin 6
IL6R interleukin 6 receptor
IL9 interleukin 9
ISG20 interferon stimulated exonuclease gene 20kDa
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
JUN jun proto-oncogene
JUNB jun B proto-oncogene
JUND jun D proto-oncogene
KAT2B K(lysine) acetyltransferase 2B
KAT6A K(lysine) acetyltransferase 6A
KAT6B K(lysine) acetyltransferase 6B
KAT8 K(lysine) acetyltransferase 8
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1
KLF15 Kruppel-like factor 15
KLF4 Kruppel-like factor 4 (gut)
KLF5 Kruppel-like factor 5 (intestinal)
KLHL35 kelch-like family member 35
KLK1 kallikrein 1
KRAS Kirsten rat sarcoma viral oncogene homolog
KRTDAP keratinocyte differentiation-associated protein
KYNU kynureninase
LANCL1 LanC lantibiotic synthetase component C-like 1 (bacterial)
LCN2 lipocalin 2
LDLR low density lipoprotein receptor
LEP leptin
LGALS3 lectin, galactoside-binding, soluble, 3
LOX lysyl oxidase
LOXL1 lysyl oxidase-like 1
LPA lipoprotein, Lp(a)
LRP1 low density lipoprotein receptor-related protein 1
LRP10 low density lipoprotein receptor-related protein 10
LRP5 low density lipoprotein receptor-related protein 5
LTA4H leukotriene A4 hydrolase
LTB lymphotoxin beta (TNF superfamily, member 3)
LTB4R leukotriene B4 receptor
LTBP3 latent transforming growth factor beta binding protein 3
LTBP4 latent transforming growth factor beta binding protein 4
LTC4S leukotriene C4 synthase
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1
MAP1B microtubule-associated protein 1B
MAP1LC3B microtubule-associated protein 1 light chain 3 beta
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MAS1 MAS1 proto-oncogene, G protein-coupled receptor
MAT2A methionine adenosyltransferase II, alpha
MBD2 methyl-CpG binding domain protein 2
MBD4 methyl-CpG binding domain protein 4
MCAM melanoma cell adhesion molecule
MCAT malonyl CoA:ACP acyltransferase (mitochondrial)
MCF2L2 MCF.2 cell line derived transforming sequence-like 2
MCTS1 malignant T cell amplified sequence 1
MDK midkine (neurite growth-promoting factor 2)
MED18 mediator complex subunit 18
MFAP1 microfibrillar-associated protein 1
MFAP4 microfibrillar-associated protein 4
MFAP5 microfibrillar associated protein 5
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MMP1 matrix metallopeptidase 1
MMP10 matrix metallopeptidase 10
MMP12 matrix metallopeptidase 12
MMP13 matrix metallopeptidase 13
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP17 matrix metallopeptidase 17 (membrane-inserted)
MMP2 matrix metallopeptidase 2
MMP3 matrix metallopeptidase 3
MMP7 matrix metallopeptidase 7
MMP8 matrix metallopeptidase 8
MMP9 matrix metallopeptidase 9
MMRN1 multimerin 1
MNDA myeloid cell nuclear differentiation antigen
MOK MOK protein kinase
MPO myeloperoxidase
MPRIP myosin phosphatase Rho interacting protein
MSC musculin
MT-ND4 NADH dehydrogenase, subunit 4 (complex I)
MT-ND5 NADH dehydrogenase, subunit 5 (complex I)
MT-ND6 NADH dehydrogenase, subunit 6 (complex I)
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MYDGF myeloid-derived growth factor
MYH10 myosin, heavy chain 10, non-muscle
MYH11 myosin, heavy chain 11, smooth muscle
MYH3 myosin, heavy chain 3, skeletal muscle, embryonic
MYLK myosin light chain kinase
MYO9B myosin IXB
MYRF myelin regulatory factor
NCF1 neutrophil cytosolic factor 1
NCOR1 nuclear receptor corepressor 1
ND1
NDE1 nudE neurodevelopment protein 1
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NF1 neurofibromin 1
NFE2L2 nuclear factor, erythroid 2-like 2
NFIB nuclear factor I/B
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NHS Nance-Horan syndrome (congenital cataracts and dental anomalies)
NKTR natural killer cell triggering receptor
NLRP3 NLR family, pyrin domain containing 3
NOD2 nucleotide-binding oligomerization domain containing 2
NONO non-POU domain containing, octamer-binding
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
NOTCH1 notch 1
NOTCH3 notch 3
NOV nephroblastoma overexpressed
NOX1 NADPH oxidase 1
NOX4 NADPH oxidase 4
NPPB natriuretic peptide B
NR1I3 nuclear receptor subfamily 1, group I, member 3
NR3C2 nuclear receptor subfamily 3, group C, member 2
NR4A3 nuclear receptor subfamily 4, group A, member 3
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
NSMCE2 non-SMC element 2, MMS21 homolog (S. cerevisiae)
NTN1 netrin 1
NUP62 nucleoporin 62kDa
OPN1LW opsin 1 (cone pigments), long-wave-sensitive
OSCP1 organic solute carrier partner 1
OSR1 odd-skipped related transciption factor 1
P2RY12 purinergic receptor P2Y, G-protein coupled, 12
PADI4 peptidyl arginine deiminase, type IV
PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1
PARP1 poly (ADP-ribose) polymerase 1
PCBP4 poly(rC) binding protein 4
PCIF1 PDX1 C-terminal inhibiting factor 1
PCSK9 proprotein convertase subtilisin/kexin type 9
PCYT1A phosphate cytidylyltransferase 1, choline, alpha
PDE3B phosphodiesterase 3B, cGMP-inhibited
PDGFA platelet-derived growth factor alpha polypeptide
PDGFD platelet derived growth factor D
PDPN podoplanin
PECAM1 platelet/endothelial cell adhesion molecule 1
PEPD peptidase D
PF4 platelet factor 4
PGR progesterone receptor
PHC1 polyhomeotic homolog 1 (Drosophila)
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PLA2G10 phospholipase A2, group X
PLA2G15 phospholipase A2, group XV
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PLAT plasminogen activator, tissue
PLAU plasminogen activator, urokinase
PLG plasminogen
POLDIP2 polymerase (DNA-directed), delta interacting protein 2
POSTN periostin, osteoblast specific factor
POTEF POTE ankyrin domain family, member F
PPARA peroxisome proliferator-activated receptor alpha
PPARG peroxisome proliferator-activated receptor gamma
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PPIA peptidylprolyl isomerase A (cyclophilin A)
PPP1R12A protein phosphatase 1, regulatory subunit 12A
PPP1R42 protein phosphatase 1, regulatory subunit 42
PRDX1 peroxiredoxin 1
PRDX2 peroxiredoxin 2
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PRKCB protein kinase C, beta
PRKG1 protein kinase, cGMP-dependent, type I
PROC protein C (inactivator of coagulation factors Va and VIIIa)
PRPF31 pre-mRNA processing factor 31
PRSS55 protease, serine, 55
PRTN3 proteinase 3
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
PTEN phosphatase and tensin homolog
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTGES prostaglandin E synthase
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTH parathyroid hormone
PTK2B protein tyrosine kinase 2 beta
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
PTPRC protein tyrosine phosphatase, receptor type, C
PTX3 pentraxin 3, long
PXDN peroxidasin
PYCARD PYD and CARD domain containing
RABEPK Rab9 effector protein with kelch motifs
RALBP1 ralA binding protein 1
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RASA1 RAS p21 protein activator (GTPase activating protein) 1
RBBP8 retinoblastoma binding protein 8
RBM45 RNA binding motif protein 45
RBM8A RNA binding motif protein 8A
RECK reversion-inducing-cysteine-rich protein with kazal motifs
REN renin
RENBP renin binding protein
RETN resistin
RGS1 regulator of G-protein signaling 1
RGS6 regulator of G-protein signaling 6
RIN2 Ras and Rab interactor 2
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RIPK3 receptor-interacting serine-threonine kinase 3
RNASE13 ribonuclease, RNase A family, 13 (non-active)
RNASEH2A ribonuclease H2, subunit A
RNASEH2B ribonuclease H2, subunit B
RNASEH2C ribonuclease H2, subunit C
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila)
ROBO4 roundabout, axon guidance receptor, homolog 4 (Drosophila)
RPSA ribosomal protein SA
RTN4 reticulon 4
RUNX2 runt-related transcription factor 2
S100A12 S100 calcium binding protein A12
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SAMHD1 SAM domain and HD domain 1
SCO2 SCO2 cytochrome c oxidase assembly protein
SDC1 syndecan 1
SELL selectin L
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SEPP1 selenoprotein P, plasma, 1
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
SETD2 SET domain containing 2
SHBG sex hormone-binding globulin
SIRT1 sirtuin 1
SKI SKI proto-oncogene
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SLC25A24 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37
SLC28A3 solute carrier family 28 (concentrative nucleoside transporter), member 3
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
SLC30A8 solute carrier family 30 (zinc transporter), member 8
SLC33A1 solute carrier family 33 (acetyl-CoA transporter), member 1
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SLPI secretory leukocyte peptidase inhibitor
SMAD2 SMAD family member 2
SMAD3 SMAD family member 3
SMAD4 SMAD family member 4
SMAD6 SMAD family member 6
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
SMYD2 SET and MYND domain containing 2
SOD1 superoxide dismutase 1, soluble
SOD2 superoxide dismutase 2, mitochondrial
SORT1 sortilin 1
SOST sclerostin
SOX9 SRY (sex determining region Y)-box 9
SPARCL1 SPARC-like 1 (hevin)
SPATC1L spermatogenesis and centriole associated 1-like
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive)
SPP1 secreted phosphoprotein 1
SPZ1 spermatogenic leucine zipper 1
SQSTM1 sequestosome 1
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)
SRFBP1 serum response factor binding protein 1
SRY sex determining region Y
STAMBPL1 STAM binding protein-like 1
STARD7 StAR-related lipid transfer (START) domain containing 7
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT5A signal transducer and activator of transcription 5A
STAT5B signal transducer and activator of transcription 5B
STIM1 stromal interaction molecule 1
STK11 serine/threonine kinase 11
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TAGLN transgelin
TBX20 T-box 20
TDRD10 tudor domain containing 10
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TGFB1 transforming growth factor, beta 1
TGFB2 transforming growth factor, beta 2
TGFB3 transforming growth factor, beta 3
TGFBR1 transforming growth factor, beta receptor 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
THBD thrombomodulin
THBS1 thrombospondin 1
TIMP1 TIMP metallopeptidase inhibitor 1
TIMP2 TIMP metallopeptidase inhibitor 2
TIMP3 TIMP metallopeptidase inhibitor 3
TIMP4 TIMP metallopeptidase inhibitor 4
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein
TK1 thymidine kinase 1, soluble
TLR2 toll-like receptor 2
TLR3 toll-like receptor 3
TLR4 toll-like receptor 4
TM7SF2 transmembrane 7 superfamily member 2
TMSB4X thymosin beta 4, X-linked
TMTC3 transmembrane and tetratricopeptide repeat containing 3
TNC tenascin C
TNF tumor necrosis factor
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFSF14 tumor necrosis factor (ligand) superfamily, member 14
TP53 tumor protein p53
TP63 tumor protein p63
TREX1 three prime repair exonuclease 1
TRIM13 tripartite motif containing 13
TRIP13 thyroid hormone receptor interactor 13
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TSC2 tuberous sclerosis 2
TSHZ1 teashirt zinc finger homeobox 1
TSPYL2 TSPY-like 2
TWIST1 twist family bHLH transcription factor 1
TXN thioredoxin
TYMS thymidylate synthetase
TYROBP TYRO protein tyrosine kinase binding protein
TYRP1 tyrosinase-related protein 1
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
UHRF1 ubiquitin-like with PHD and ring finger domains 1
UMOD uromodulin
UQCRFS1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1
UTS2 urotensin 2
UTS2R urotensin 2 receptor
VCAM1 vascular cell adhesion molecule 1
VCAN versican
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
VIM vimentin
VKORC1 vitamin K epoxide reductase complex, subunit 1
VPS51 vacuolar protein sorting 51 homolog (S. cerevisiae)
VTN vitronectin
VWF von Willebrand factor
WDTC1 WD and tetratricopeptide repeats 1
XBP1 X-box binding protein 1
XYLT1 xylosyltransferase I
ZBTB16 zinc finger and BTB domain containing 16
ZC3H12A zinc finger CCCH-type containing 12A
ZGLP1 zinc finger, GATA-like protein 1
ZIC3 Zic family member 3
ZNF148 zinc finger protein 148
ZNF335 zinc finger protein 335