| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Apalutamide perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Apalutamide_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.150556 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.141348 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.134377 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.132817 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.130387 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.126333 |
| ANXA2 | annexin A2 | 0.118488 |
| LDHA | lactate dehydrogenase A | 0.107232 |
| FNDC3B | fibronectin type III domain containing 3B | 0.08914 |
| CD44 | CD44 molecule (Indian blood group) | 0.0851988 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.081648 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0765041 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0723214 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0706099 |
| UBC | ubiquitin C | 0.068691 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0686666 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0675858 |
| RTN4 | reticulon 4 | 0.0668241 |
| PODXL | podocalyxin-like | 0.0666666 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0658004 |
| PKM | pyruvate kinase, muscle | 0.0656656 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0654852 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0649744 |
| DST | dystonin | 0.0649691 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0606691 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0600548 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0547108 |
| FLNB | filamin B, beta | 0.0537004 |
| MAP1B | microtubule-associated protein 1B | 0.0533267 |
| POTEF | POTE ankyrin domain family, member F | 0.0526795 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0524672 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0505937 |
| COL5A2 | collagen, type V, alpha 2 | 0.0505779 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0492314 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0481802 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0463702 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.045223 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0431196 |
| OPTN | optineurin | 0.043037 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0425317 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0421325 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0421151 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0419415 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0416537 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0404044 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0397682 |
| RND3 | Rho family GTPase 3 | 0.0394573 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.039308 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0389734 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | 0.0386793 |
| CENPF | centromere protein F, 350/400kDa | 0.0384248 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0382358 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | 0.0372725 |
| MB21D2 | Mab-21 domain containing 2 | 0.03714 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0368241 |
| ASPH | aspartate beta-hydroxylase | 0.036263 |
| SEPTIN7 | septin 7 | 0.0361849 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0360145 |
| ADM | adrenomedullin | 0.0359001 |
| NDRG1 | N-myc downstream regulated 1 | 0.0356675 |
| COPA | coatomer protein complex, subunit alpha | 0.0349812 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0349339 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0341987 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0340426 |
| RUNX1 | runt-related transcription factor 1 | 0.0340426 |
| TPM3 | tropomyosin 3 | 0.0339998 |
| B2M | beta-2-microglobulin | 0.0336077 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0334154 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.033337 |
| MYOF | myoferlin | 0.0330577 |
| ZNF292 | zinc finger protein 292 | 0.0330112 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0328727 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0328162 |
| IL6ST | interleukin 6 signal transducer | 0.0327155 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.032698 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.032557 |
| TFG | TRK-fused gene | 0.0322211 |
| ZNF207 | zinc finger protein 207 | 0.0319494 |
| VCL | vinculin | 0.0318157 |
| C1D | C1D nuclear receptor corepressor | 0.0313616 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0312503 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0310809 |
| XPO1 | exportin 1 | 0.0310215 |
| MSN | moesin | 0.0308922 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0308045 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0305596 |
| COL4A1 | collagen, type IV, alpha 1 | 0.030346 |
| ANXA5 | annexin A5 | 0.0303084 |
| HELZ | helicase with zinc finger | 0.0302667 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0301308 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0301183 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.029607 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.029407 |
| UBQLN1 | ubiquilin 1 | 0.0292529 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0292081 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0288494 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0286765 |
| AFF4 | AF4/FMR2 family, member 4 | 0.028629 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0283427 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0281654 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.169013 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.148202 |
| VIM | vimentin | -0.125704 |
| MT2A | metallothionein 2A | -0.100772 |
| HLA-B | major histocompatibility complex, class I, B | -0.0794275 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0578028 |
| SUCNR1 | succinate receptor 1 | -0.0503984 |
| COL1A2 | collagen, type I, alpha 2 | -0.0484143 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0478108 |
| CDH13 | cadherin 13 | -0.0448918 |
| AHNAK | AHNAK nucleoprotein | -0.0438494 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0437555 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0433331 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0432655 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0418216 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0397561 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0389286 |
| PRSS23 | protease, serine, 23 | -0.0385574 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0377594 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0377048 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0351382 |
| FRMD5 | FERM domain containing 5 | -0.0334166 |
| RPS19 | ribosomal protein S19 | -0.0330884 |
| PTMA | prothymosin, alpha | -0.0315117 |
| JAZF1 | JAZF zinc finger 1 | -0.0313855 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0311146 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0298961 |
| LMNA | lamin A/C | -0.0298744 |
| RPL12 | ribosomal protein L12 | -0.0289597 |
| CDK13 | cyclin-dependent kinase 13 | -0.0289157 |
| EHBP1 | EH domain binding protein 1 | -0.0288401 |
| FRMD4A | FERM domain containing 4A | -0.0286795 |
| RPLP2 | ribosomal protein, large, P2 | -0.0273185 |
| FN1 | fibronectin 1 | -0.0269206 |
| RPL36 | ribosomal protein L36 | -0.0267864 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0266946 |
| SYT1 | synaptotagmin I | -0.0263073 |
| TBCA | tubulin folding cofactor A | -0.0262496 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0257933 |
| RPS3 | ribosomal protein S3 | -0.0257336 |
| TMSB4X | thymosin beta 4, X-linked | -0.0255652 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.0250954 |
| HLA-E | major histocompatibility complex, class I, E | -0.0250317 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0244466 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0243222 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0239216 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | -0.0238673 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.023827 |
| HOXD10 | homeobox D10 | -0.0236546 |
| LOX | lysyl oxidase | -0.0228367 |
| ACTG1 | actin gamma 1 | -0.022759 |
| PRRX1 | paired related homeobox 1 | -0.022716 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0225259 |
| MT1X | metallothionein 1X | -0.0224361 |
| COL5A1 | collagen, type V, alpha 1 | -0.0222118 |
| RPL37A | ribosomal protein L37a | -0.0220974 |
| CUX1 | cut-like homeobox 1 | -0.0220135 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.021912 |
| COL1A1 | collagen, type I, alpha 1 | -0.0218602 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0215976 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0212824 |
| RPL31 | ribosomal protein L31 | -0.0212071 |
| LDLRAD4 | low density lipoprotein receptor class A domain containing 4 | -0.0206694 |
| TCF12 | transcription factor 12 | -0.020215 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.0202112 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0201523 |
| RPS27A | ribosomal protein S27a | -0.0198806 |
| RPL32 | ribosomal protein L32 | -0.0197882 |
| FAM114A1 | family with sequence similarity 114, member A1 | -0.0197518 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0195869 |
| SLC39A11 | solute carrier family 39, member 11 | -0.0194915 |
| EGFR | epidermal growth factor receptor | -0.0194174 |
| MRC2 | mannose receptor, C type 2 | -0.0193135 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0193006 |
| COL3A1 | collagen, type III, alpha 1 | -0.0192929 |
| CCND1 | cyclin D1 | -0.0191885 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0190961 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0189863 |
| CAVIN1 | caveolae associated protein 1 | -0.0189176 |
| CDK14 | cyclin-dependent kinase 14 | -0.0188734 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0188717 |
| CD59 | CD59 molecule, complement regulatory protein | -0.0188519 |
| RPL35A | ribosomal protein L35a | -0.0186957 |
| HLCS | holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) | -0.0186484 |
| ZXDC | ZXD family zinc finger C | -0.0185518 |
| EFNA5 | ephrin-A5 | -0.0185511 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0180843 |
| RPS8 | ribosomal protein S8 | -0.0180339 |
| RPL23 | ribosomal protein L23 | -0.0179421 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0179028 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0177273 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0176806 |
| HLA-C | major histocompatibility complex, class I, C | -0.01764 |
| DLGAP3 | discs, large (Drosophila) homolog-associated protein 3 | -0.0176129 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0173995 |
| RPL37 | ribosomal protein L37 | -0.0171184 |
| ARL15 | ADP-ribosylation factor-like 15 | -0.0170819 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | -0.0169454 |
| CMIP | c-Maf inducing protein | -0.0168202 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0166644 |
