| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Apalutamide perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Apalutamide_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0707763 |
| DST | dystonin | 0.0692958 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0686532 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0607377 |
| AREG | amphiregulin | 0.0599014 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.058656 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0570536 |
| PCBP2 | poly(rC) binding protein 2 | 0.0554686 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0546857 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0520571 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0508913 |
| TXNRD1 | thioredoxin reductase 1 | 0.049157 |
| CELF2 | CUGBP, Elav-like family member 2 | 0.0479639 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0430718 |
| PCM1 | pericentriolar material 1 | 0.0396738 |
| EXOC6B | exocyst complex component 6B | 0.0384928 |
| CXADR | coxsackie virus and adenovirus receptor | 0.0384184 |
| KIF5B | kinesin family member 5B | 0.0382903 |
| CRISPLD1 | cysteine-rich secretory protein LCCL domain containing 1 | 0.0346965 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0343085 |
| ANXA1 | annexin A1 | 0.0343071 |
| XPO1 | exportin 1 | 0.0338159 |
| PLK2 | polo-like kinase 2 | 0.0334812 |
| SLC38A2 | solute carrier family 38, member 2 | 0.033301 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0331235 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0319518 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0303945 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0301945 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0296726 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.0296624 |
| PRKCI | protein kinase C, iota | 0.0292338 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0288043 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0286462 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0281002 |
| NEK7 | NIMA-related kinase 7 | 0.0279854 |
| KIF1B | kinesin family member 1B | 0.0272838 |
| OLR1 | oxidized low density lipoprotein (lectin-like) receptor 1 | 0.0272246 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0272076 |
| IL6ST | interleukin 6 signal transducer | 0.0271131 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0269122 |
| TENM3 | teneurin transmembrane protein 3 | 0.0265022 |
| LMO7 | LIM domain 7 | 0.0264297 |
| TPM3 | tropomyosin 3 | 0.0263676 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0257175 |
| LDHA | lactate dehydrogenase A | 0.0249201 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0240844 |
| EDN1 | endothelin 1 | 0.0240735 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.023941 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 | 0.0238602 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0235118 |
| OXR1 | oxidation resistance 1 | 0.0234548 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.023334 |
| SBF2 | SET binding factor 2 | 0.0230083 |
| TPR | translocated promoter region, nuclear basket protein | 0.0226106 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0219509 |
| VIM | vimentin | 0.0213608 |
| CEP95 | centrosomal protein 95kDa | 0.0213228 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.021256 |
| HELB | helicase (DNA) B | 0.0211823 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 | 0.0211788 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0209872 |
| CCDC88A | coiled-coil domain containing 88A | 0.0205816 |
| LRP6 | low density lipoprotein receptor-related protein 6 | 0.0204455 |
| DDB2 | damage-specific DNA binding protein 2, 48kDa | 0.0204411 |
| CCNL1 | cyclin L1 | 0.0203039 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0202399 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0202145 |
| PREPL | prolyl endopeptidase-like | 0.0201061 |
| KLHL24 | kelch-like family member 24 | 0.0200619 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0199461 |
| ATP11A | ATPase, class VI, type 11A | 0.0198381 |
| BLTP1 | bridge-like lipid transfer protein family member 1 | 0.0196715 |
| YEATS2 | YEATS domain containing 2 | 0.0188205 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0187127 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | 0.0186887 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0183815 |
| THOC2 | THO complex 2 | 0.0183569 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.0182736 |
| IPMK | inositol polyphosphate multikinase | 0.0182391 |
| GOLGB1 | golgin B1 | 0.0181997 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0181674 |
| AXIN2 | axin 2 | 0.0179782 |
| CENPF | centromere protein F, 350/400kDa | 0.017968 |
| NUP58 | nucleoporin 58 | 0.0179016 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | 0.0177432 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0175635 |
| DSPP | dentin sialophosphoprotein | 0.0175344 |
| GOLT1A | golgi transport 1A | 0.0174731 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.0174632 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0173756 |
| NRXN3 | neurexin 3 | 0.0173051 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0172548 |
| SET | SET nuclear proto-oncogene | 0.0171927 |
| EPHA6 | EPH receptor A6 | 0.017159 |
| EZR | ezrin | 0.0170804 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0169534 |
| MPG | N-methylpurine-DNA glycosylase | 0.0168569 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.016766 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0166861 |
| NKTR | natural killer cell triggering receptor | 0.0166694 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.200806 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.133838 |
| HMGA2 | high mobility group AT-hook 2 | -0.103571 |
| NLGN1 | neuroligin 1 | -0.0995471 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0941941 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0801992 |
| PTMA | prothymosin, alpha | -0.0791813 |
| RPL23 | ribosomal protein L23 | -0.0719675 |
| FTL | ferritin, light polypeptide | -0.0714224 |
| ACTG1 | actin gamma 1 | -0.0669246 |
| RPS19 | ribosomal protein S19 | -0.0648545 |
| RPL37A | ribosomal protein L37a | -0.064714 |
| RPS8 | ribosomal protein S8 | -0.064131 |
| RPS12 | ribosomal protein S12 | -0.0640815 |
| RPL35A | ribosomal protein L35a | -0.0619453 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0571536 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0567501 |
| RPLP2 | ribosomal protein, large, P2 | -0.0561404 |
| RPS3 | ribosomal protein S3 | -0.0549916 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0545424 |
| RPS6 | ribosomal protein S6 | -0.0537386 |
| RPS27A | ribosomal protein S27a | -0.0532748 |
| RPS23 | ribosomal protein S23 | -0.0524645 |
| RPS29 | ribosomal protein S29 | -0.0524253 |
| RPLP1 | ribosomal protein, large, P1 | -0.0520358 |
| RPS21 | ribosomal protein S21 | -0.0497423 |
| RPL19 | ribosomal protein L19 | -0.0496736 |
| ASPH | aspartate beta-hydroxylase | -0.0488132 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0480365 |
| NHSL1 | NHS-like 1 | -0.0477789 |
| BCHE | butyrylcholinesterase | -0.0465332 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.0434699 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | -0.0433313 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0426799 |
| RPL37 | ribosomal protein L37 | -0.0426526 |
| RPL36 | ribosomal protein L36 | -0.0426476 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0411547 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0405124 |
| RPL12 | ribosomal protein L12 | -0.0404593 |
| RPL34 | ribosomal protein L34 | -0.0401546 |
| RPS13 | ribosomal protein S13 | -0.0400417 |
| RPL31 | ribosomal protein L31 | -0.0378018 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0372503 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.0365825 |
| PCDH7 | protocadherin 7 | -0.0364329 |
| RPL38 | ribosomal protein L38 | -0.036328 |
| RPS15 | ribosomal protein S15 | -0.0361438 |
| RPL26 | ribosomal protein L26 | -0.0356518 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0340614 |
| RPS14 | ribosomal protein S14 | -0.0335014 |
| RPL9 | ribosomal protein L9 | -0.0334853 |
| GNAS | GNAS complex locus | -0.0334263 |
| CUX1 | cut-like homeobox 1 | -0.0331504 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | -0.0324912 |
| RPS24 | ribosomal protein S24 | -0.0324771 |
| NAV3 | neuron navigator 3 | -0.0322563 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.031464 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0312836 |
| INTS6 | integrator complex subunit 6 | -0.0311408 |
| YAP1 | Yes-associated protein 1 | -0.0310207 |
| RPS27 | ribosomal protein S27 | -0.0306411 |
| PCDH9 | protocadherin 9 | -0.030183 |
| RPL11 | ribosomal protein L11 | -0.0298852 |
| S100A10 | S100 calcium binding protein A10 | -0.0297831 |
| PDGFC | platelet derived growth factor C | -0.0296303 |
| TBCA | tubulin folding cofactor A | -0.0293354 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0292852 |
| RPLP0 | ribosomal protein, large, P0 | -0.0292664 |
| RPL8 | ribosomal protein L8 | -0.0291316 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0289068 |
| ADIPOR2 | adiponectin receptor 2 | -0.0284138 |
| EHBP1 | EH domain binding protein 1 | -0.0282521 |
| RPS11 | ribosomal protein S11 | -0.0281995 |
| RPS17 | ribosomal protein S17 | -0.0281911 |
| RPL27 | ribosomal protein L27 | -0.0273729 |
| JMJD1C | jumonji domain containing 1C | -0.0268246 |
| RPS10 | ribosomal protein S10 | -0.0265047 |
| RPS25 | ribosomal protein S25 | -0.0261904 |
| CANX | calnexin | -0.026073 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.025943 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0255709 |
| CALR | calreticulin | -0.0254785 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0253869 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0252266 |
| TUBB | tubulin, beta class I | -0.0249249 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0248504 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | -0.0246957 |
| RPL32 | ribosomal protein L32 | -0.0246249 |
| RPL28 | ribosomal protein L28 | -0.0245917 |
| RRM2 | ribonucleotide reductase M2 | -0.0242174 |
| RPS20 | ribosomal protein S20 | -0.0236412 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.023367 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0232605 |
| RPL36A | ribosomal protein L36a | -0.0231704 |
| TUBA1B | tubulin, alpha 1b | -0.0229967 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0227715 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0227512 |
| S100A9 | S100 calcium binding protein A9 | -0.0225882 |
| TPM4 | tropomyosin 4 | -0.0223393 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0223098 |
