| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Apalutamide perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Apalutamide_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.260589 |
| FN1 | fibronectin 1 | 0.0773282 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0312081 |
| RPS6 | ribosomal protein S6 | 0.0251139 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0185992 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | 0.0185281 |
| GOLGA4 | golgin A4 | 0.0178551 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0172525 |
| CDH13 | cadherin 13 | 0.0163923 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.016055 |
| KLF6 | Kruppel-like factor 6 | 0.0156526 |
| MAP1B | microtubule-associated protein 1B | 0.0155339 |
| VEGFA | vascular endothelial growth factor A | 0.0154752 |
| PRELID2 | PRELI domain containing 2 | 0.0154438 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0147324 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0142706 |
| DST | dystonin | 0.0133033 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.0127765 |
| RPL13A | ribosomal protein L13a | 0.0127539 |
| ANXA2 | annexin A2 | 0.0125388 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0124839 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | 0.0122295 |
| RPS19 | ribosomal protein S19 | 0.0121319 |
| PDE10A | phosphodiesterase 10A | 0.0118198 |
| RPL35A | ribosomal protein L35a | 0.0115939 |
| VCAN | versican | 0.0114608 |
| EFNA5 | ephrin-A5 | 0.0114479 |
| TRPS1 | trichorhinophalangeal syndrome I | 0.0112313 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.0107166 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0106867 |
| GOLGB1 | golgin B1 | 0.0105801 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0103418 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0103166 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0100412 |
| RND3 | Rho family GTPase 3 | 0.0100202 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.00981301 |
| RPS23 | ribosomal protein S23 | 0.00930923 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.00918094 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.00915796 |
| RAI14 | retinoic acid induced 14 | 0.00905551 |
| CDC27 | cell division cycle 27 | 0.00891371 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.00889404 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.00882132 |
| RPS2 | ribosomal protein S2 | 0.00875649 |
| OPTN | optineurin | 0.00851517 |
| CNTN5 | contactin 5 | 0.00820588 |
| RPL12 | ribosomal protein L12 | 0.00807184 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.00792555 |
| CD47 | CD47 molecule | 0.00785477 |
| RASA2 | RAS p21 protein activator 2 | 0.00779632 |
| EGR1 | early growth response 1 | 0.00773568 |
| YEATS2 | YEATS domain containing 2 | 0.00770036 |
| NKTR | natural killer cell triggering receptor | 0.00769648 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.00768635 |
| GPC6 | glypican 6 | 0.00766473 |
| ZMAT4 | zinc finger, matrin-type 4 | 0.00755535 |
| ANKRD11 | ankyrin repeat domain 11 | 0.00754814 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.00750963 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.00741311 |
| TMEM41B | transmembrane protein 41B | 0.00740266 |
| CCDC88A | coiled-coil domain containing 88A | 0.00739158 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.00736481 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.00732207 |
| CLMP | CXADR-like membrane protein | 0.00729183 |
| RPS4X | ribosomal protein S4, X-linked | 0.00728119 |
| MEF2A | myocyte enhancer factor 2A | 0.00715086 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.00713561 |
| GANAB | glucosidase, alpha; neutral AB | 0.00711449 |
| VASP | vasodilator-stimulated phosphoprotein | 0.00706982 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.00686362 |
| PDCD5 | programmed cell death 5 | 0.00683039 |
| NME2 | NME/NM23 nucleoside diphosphate kinase 2 | 0.00682718 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.00673164 |
| ATP13A3 | ATPase type 13A3 | 0.00672849 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.00665345 |
| TPR | translocated promoter region, nuclear basket protein | 0.00662605 |
| MTCH1 | mitochondrial carrier 1 | 0.00658623 |
| NCKAP1 | NCK-associated protein 1 | 0.00658525 |
| ZNF292 | zinc finger protein 292 | 0.00657716 |
| NUB1 | negative regulator of ubiquitin-like proteins 1 | 0.00653788 |
| RPL36 | ribosomal protein L36 | 0.0064516 |
| RPS3 | ribosomal protein S3 | 0.00642366 |
| BAG6 | BCL2-associated athanogene 6 | 0.00633564 |
| TENM3 | teneurin transmembrane protein 3 | 0.00632659 |
| RPL32 | ribosomal protein L32 | 0.00632647 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0063207 |
| RPL35 | ribosomal protein L35 | 0.00625844 |
| H1-4 | H1.4 linker histone, cluster member | 0.0062327 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | 0.00621832 |
| OXR1 | oxidation resistance 1 | 0.00610427 |
| PDE8A | phosphodiesterase 8A | 0.00608527 |
| TMEM59 | transmembrane protein 59 | 0.00596242 |
| SBF2 | SET binding factor 2 | 0.0059165 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.00589612 |
| CENPF | centromere protein F, 350/400kDa | 0.00588561 |
| HSPB11 | heat shock protein family B (small), member 11 | 0.00586127 |
| SCFD1 | sec1 family domain containing 1 | 0.00584875 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.00583407 |
| ATRN | attractin | 0.00578568 |
| ATF4 | activating transcription factor 4 | 0.00577164 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.164476 |
| COL1A1 | collagen, type I, alpha 1 | -0.149737 |
| VIM | vimentin | -0.141192 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.13939 |
| UBC | ubiquitin C | -0.107521 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0832002 |
| ENO1 | enolase 1, (alpha) | -0.0814438 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0678319 |
| CD44 | CD44 molecule (Indian blood group) | -0.0677539 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0634617 |
| AHNAK | AHNAK nucleoprotein | -0.0609403 |
| COL1A2 | collagen, type I, alpha 2 | -0.0575643 |
| CALR | calreticulin | -0.0548736 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0543017 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0540071 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0457469 |
| CANX | calnexin | -0.0452798 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0447267 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0442505 |
| TMSB10 | thymosin beta 10 | -0.0434798 |
| INHBA | inhibin, beta A | -0.0391666 |
| CALU | calumenin | -0.0371649 |
| IER3 | immediate early response 3 | -0.037027 |
| PKM | pyruvate kinase, muscle | -0.0337082 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0325799 |
| PTMA | prothymosin, alpha | -0.0318118 |
| RPS27A | ribosomal protein S27a | -0.0297932 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0297156 |
| JUN | jun proto-oncogene | -0.0291533 |
| FBN1 | fibrillin 1 | -0.0277455 |
| CLIC4 | chloride intracellular channel 4 | -0.0276914 |
| LOC112694756 | uncharaterized LOC112694756 | -0.027439 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0269439 |
| LOX | lysyl oxidase | -0.0264736 |
| MT1X | metallothionein 1X | -0.025542 |
| STC1 | stanniocalcin 1 | -0.024591 |
| MT2A | metallothionein 2A | -0.0240971 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0238651 |
| NDRG1 | N-myc downstream regulated 1 | -0.0237624 |
| PLEC | plectin | -0.0227772 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0218147 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.021448 |
| APP | amyloid beta (A4) precursor protein | -0.0213749 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0210515 |
| FLNA | filamin A, alpha | -0.0196825 |
| IL6 | interleukin 6 | -0.019605 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0191026 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0190461 |
| TMSB4X | thymosin beta 4, X-linked | -0.0187074 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0184783 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0184099 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0181119 |
| DPYSL2 | dihydropyrimidinase-like 2 | -0.0179292 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0171184 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0170403 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0169446 |
| HLA-E | major histocompatibility complex, class I, E | -0.0169196 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -0.0169084 |
| HLA-B | major histocompatibility complex, class I, B | -0.0168426 |
| S100A6 | S100 calcium binding protein A6 | -0.0166987 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0165083 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0164396 |
| TNIP1 | TNFAIP3 interacting protein 1 | -0.0159416 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0159216 |
| MYO9B | myosin IXB | -0.0157734 |
| S100A10 | S100 calcium binding protein A10 | -0.015484 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0153884 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0152116 |
| HDLBP | high density lipoprotein binding protein | -0.0151146 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0150679 |
| COL3A1 | collagen, type III, alpha 1 | -0.014874 |
| TPM4 | tropomyosin 4 | -0.0147986 |
| COL5A1 | collagen, type V, alpha 1 | -0.0147146 |
| PCBP2 | poly(rC) binding protein 2 | -0.0146088 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0143061 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.014279 |
| GLG1 | golgi glycoprotein 1 | -0.0141721 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | -0.0137975 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.013516 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -0.0134775 |
| RPL23 | ribosomal protein L23 | -0.0133736 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.012628 |
| IL6ST | interleukin 6 signal transducer | -0.0123593 |
| CD82 | CD82 molecule | -0.012253 |
| FAT1 | FAT atypical cadherin 1 | -0.0122337 |
| ARRDC3 | arrestin domain containing 3 | -0.0121694 |
| DUSP6 | dual specificity phosphatase 6 | -0.0121642 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0119341 |
| POTEF | POTE ankyrin domain family, member F | -0.0116979 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | -0.0115977 |
| COL4A1 | collagen, type IV, alpha 1 | -0.0115178 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0114183 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0113322 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0112462 |
| EMC1 | ER membrane protein complex subunit 1 | -0.0110835 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0110599 |
| MATR3 | matrin 3 | -0.0110451 |
| NOTCH2 | notch 2 | -0.0110382 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0109015 |
| ACTN4 | actinin, alpha 4 | -0.0108957 |
