| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Apalutamide perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Apalutamide_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NRIP1 | nuclear receptor interacting protein 1 | 0.0559811 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0540058 |
| FOXO1 | forkhead box O1 | 0.0529396 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.050515 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0502035 |
| MTSS1 | metastasis suppressor 1 | 0.049783 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0493401 |
| FLNB | filamin B, beta | 0.0485414 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 0.0462653 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0456331 |
| SMAD3 | SMAD family member 3 | 0.0418392 |
| LMO7 | LIM domain 7 | 0.0405785 |
| RAI14 | retinoic acid induced 14 | 0.0367225 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0354057 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0319784 |
| MECOM | MDS1 and EVI1 complex locus | 0.0318436 |
| BCL2L1 | BCL2-like 1 | 0.0306809 |
| NEK7 | NIMA-related kinase 7 | 0.0303443 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0293519 |
| PRELID2 | PRELI domain containing 2 | 0.0279081 |
| RASAL2 | RAS protein activator like 2 | 0.0272545 |
| ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif, 16 | 0.0271056 |
| DOCK9 | dedicator of cytokinesis 9 | 0.0257419 |
| AOPEP | aminopeptidase O (putative) | 0.0255993 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0254314 |
| SULF1 | sulfatase 1 | 0.0253282 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0252289 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0247396 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0238231 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0238158 |
| VCL | vinculin | 0.0232673 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0230848 |
| RIN2 | Ras and Rab interactor 2 | 0.0230426 |
| MYOF | myoferlin | 0.0230084 |
| CAPRIN2 | caprin family member 2 | 0.0228309 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.022711 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0227015 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | 0.022675 |
| OSMR | oncostatin M receptor | 0.0226383 |
| AMOTL1 | angiomotin like 1 | 0.0224775 |
| SMYD3 | SET and MYND domain containing 3 | 0.0216192 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | 0.0210468 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0206317 |
| EFNA5 | ephrin-A5 | 0.0197353 |
| KIAA1217 | KIAA1217 | 0.0195806 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | 0.0195262 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0194762 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | 0.0193597 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0191109 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0190627 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0188159 |
| DST | dystonin | 0.0182121 |
| FOXP1 | forkhead box P1 | 0.0181037 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0180809 |
| EXOC4 | exocyst complex component 4 | 0.0178224 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0176456 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0174322 |
| MSN | moesin | 0.0167822 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.0167586 |
| TNS3 | tensin 3 | 0.0167055 |
| LUZP1 | leucine zipper protein 1 | 0.0166891 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.0166637 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0165614 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.016429 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0163484 |
| SLTM | SAFB-like, transcription modulator | 0.0161533 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0159775 |
| RAD51B | RAD51 paralog B | 0.0158921 |
| FNIP1 | folliculin interacting protein 1 | 0.015874 |
| SEPTIN9 | septin 9 | 0.0158514 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0157182 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0156645 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0156624 |
| UTRN | utrophin | 0.0155773 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0155733 |
| C4BPB | complement component 4 binding protein, beta | 0.0155039 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | 0.0153345 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.015187 |
| EXOC6B | exocyst complex component 6B | 0.0151854 |
| NRG1 | neuregulin 1 | 0.0150714 |
| ASPH | aspartate beta-hydroxylase | 0.0148842 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0148618 |
| MEGF6 | multiple EGF-like-domains 6 | 0.0148267 |
| BLCAP | bladder cancer associated protein | 0.0147911 |
| ATXN1 | ataxin 1 | 0.0146775 |
| SETX | senataxin | 0.0145611 |
| TJP1 | tight junction protein 1 | 0.0145248 |
| KLF12 | Kruppel-like factor 12 | 0.0143295 |
| HDAC9 | histone deacetylase 9 | 0.0143064 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0141819 |
| OSBPL3 | oxysterol binding protein-like 3 | 0.0141062 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0140101 |
| ITSN1 | intersectin 1 (SH3 domain protein) | 0.0139219 |
| TENM4 | teneurin transmembrane protein 4 | 0.0137685 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.0137071 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0136233 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0136195 |
| ANO6 | anoctamin 6 | 0.0135195 |
| FAM107B | family with sequence similarity 107, member B | 0.0135163 |
| PLXNA2 | plexin A2 | 0.0134414 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.195609 |
| PTMA | prothymosin, alpha | -0.121995 |
| NDRG1 | N-myc downstream regulated 1 | -0.119005 |
| TMSB10 | thymosin beta 10 | -0.117384 |
| MT2A | metallothionein 2A | -0.11611 |
| B2M | beta-2-microglobulin | -0.113666 |
| RPS6 | ribosomal protein S6 | -0.103744 |
| RPS21 | ribosomal protein S21 | -0.0975685 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0973656 |
| S100A10 | S100 calcium binding protein A10 | -0.0903435 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0892185 |
| CLU | clusterin | -0.0890601 |
| RPS8 | ribosomal protein S8 | -0.0871623 |
| RPLP2 | ribosomal protein, large, P2 | -0.0836044 |
| RPS13 | ribosomal protein S13 | -0.0713347 |
| RPS19 | ribosomal protein S19 | -0.0692746 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0684762 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0681161 |
| RPL11 | ribosomal protein L11 | -0.0661579 |
| TMSB4X | thymosin beta 4, X-linked | -0.0653422 |
| ENO1 | enolase 1, (alpha) | -0.0633562 |
| RPS3 | ribosomal protein S3 | -0.0614756 |
| RPLP1 | ribosomal protein, large, P1 | -0.0607526 |
| GNAS | GNAS complex locus | -0.0597374 |
| KRT17 | keratin 17, type I | -0.0585468 |
| STC1 | stanniocalcin 1 | -0.0577535 |
| FTL | ferritin, light polypeptide | -0.057046 |
| LMNA | lamin A/C | -0.0561009 |
| RPS12 | ribosomal protein S12 | -0.0546295 |
| LDHA | lactate dehydrogenase A | -0.0534939 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0532255 |
| HLA-B | major histocompatibility complex, class I, B | -0.0528784 |
| PGK1 | phosphoglycerate kinase 1 | -0.0526877 |
| S100A6 | S100 calcium binding protein A6 | -0.0516649 |
| RPL23 | ribosomal protein L23 | -0.0514605 |
| S100A9 | S100 calcium binding protein A9 | -0.0510581 |
| RPL8 | ribosomal protein L8 | -0.0494437 |
| RPL37 | ribosomal protein L37 | -0.048558 |
| S100A2 | S100 calcium binding protein A2 | -0.0475209 |
| RPL12 | ribosomal protein L12 | -0.0467762 |
| RPL37A | ribosomal protein L37a | -0.0466373 |
| RPS25 | ribosomal protein S25 | -0.0458886 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0450831 |
| RPL35A | ribosomal protein L35a | -0.0447783 |
| RPS23 | ribosomal protein S23 | -0.044701 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0445811 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0440247 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0429247 |
| RPL19 | ribosomal protein L19 | -0.0427999 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0423426 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0419567 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0419463 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0417942 |
| S100A11 | S100 calcium binding protein A11 | -0.0416056 |
| RPS24 | ribosomal protein S24 | -0.0416007 |
| RPS29 | ribosomal protein S29 | -0.0406611 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0404138 |
| RPL34 | ribosomal protein L34 | -0.0400317 |
| RPS14 | ribosomal protein S14 | -0.0398155 |
| MT1X | metallothionein 1X | -0.0391842 |
| RPL31 | ribosomal protein L31 | -0.038569 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.038435 |
| RPS27 | ribosomal protein S27 | -0.0381006 |
| RPL26 | ribosomal protein L26 | -0.0378634 |
| DSTN | destrin (actin depolymerizing factor) | -0.0376818 |
| RPS27A | ribosomal protein S27a | -0.0375596 |
| RPL36 | ribosomal protein L36 | -0.0374838 |
| RPLP0 | ribosomal protein, large, P0 | -0.0374352 |
| RPL32 | ribosomal protein L32 | -0.0372124 |
| YBX1 | Y box binding protein 1 | -0.0371176 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.036978 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0364907 |
| RPL35 | ribosomal protein L35 | -0.0360645 |
| GOLGA4 | golgin A4 | -0.0358933 |
| ANXA1 | annexin A1 | -0.035823 |
| PKM | pyruvate kinase, muscle | -0.0353396 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.0348452 |
| RPL7A | ribosomal protein L7a | -0.0344953 |
| RACK1 | receptor for activated C kinase 1 | -0.0342873 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.033923 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0338229 |
| RPS11 | ribosomal protein S11 | -0.0337994 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0333074 |
| RPL27A | ribosomal protein L27a | -0.0331761 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0330061 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0329399 |
| RPL28 | ribosomal protein L28 | -0.0319041 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0315616 |
| RPL9 | ribosomal protein L9 | -0.0315023 |
| RPS16 | ribosomal protein S16 | -0.0310434 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0304623 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0303986 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0302264 |
| RPL5 | ribosomal protein L5 | -0.0299528 |
| COX4I1 | cytochrome c oxidase subunit IV isoform 1 | -0.0297954 |
| PFN1 | profilin 1 | -0.0296871 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0295223 |
| RPS17 | ribosomal protein S17 | -0.029398 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0292575 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0292431 |
