| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Apalutamide perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Apalutamide_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.266626 |
| FAT1 | FAT atypical cadherin 1 | 0.109996 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0925217 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0790694 |
| DSPP | dentin sialophosphoprotein | 0.0752226 |
| ANXA2 | annexin A2 | 0.0745159 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0725423 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0722148 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0715935 |
| LDHA | lactate dehydrogenase A | 0.068803 |
| GOLGA4 | golgin A4 | 0.0663344 |
| CALR | calreticulin | 0.0593846 |
| RNF43 | ring finger protein 43 | 0.0578299 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0574123 |
| CANX | calnexin | 0.0552161 |
| EREG | epiregulin | 0.0548406 |
| PRELID2 | PRELI domain containing 2 | 0.050254 |
| NDRG1 | N-myc downstream regulated 1 | 0.0499215 |
| GOLGB1 | golgin B1 | 0.0479231 |
| RPL13A | ribosomal protein L13a | 0.0468805 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0441851 |
| EZR | ezrin | 0.0423431 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0412607 |
| CADPS | Ca++-dependent secretion activator | 0.0405709 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0403454 |
| FAM13A | family with sequence similarity 13, member A | 0.0389548 |
| LMO7 | LIM domain 7 | 0.0387459 |
| ONECUT3 | one cut homeobox 3 | 0.0387375 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0385552 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.037891 |
| RPS3 | ribosomal protein S3 | 0.0377521 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0377166 |
| OGA | O-GlcNAcase | 0.0377016 |
| RBM39 | RNA binding motif protein 39 | 0.0372285 |
| NEBL | nebulette | 0.0364031 |
| ATXN1 | ataxin 1 | 0.0359769 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0355444 |
| H1-0 | H1.0 linker histone | 0.0354241 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0352185 |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) | 0.0351004 |
| RPS2 | ribosomal protein S2 | 0.0350442 |
| S100P | S100 calcium binding protein P | 0.0347336 |
| KIF5B | kinesin family member 5B | 0.0346021 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0342196 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0340095 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0336682 |
| EPCAM | epithelial cell adhesion molecule | 0.0333901 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0326698 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0326497 |
| MUC13 | mucin 13, cell surface associated | 0.0323357 |
| DSG2 | desmoglein 2 | 0.0322865 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0319522 |
| CD47 | CD47 molecule | 0.0313743 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0311341 |
| RPL26 | ribosomal protein L26 | 0.0309095 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0307975 |
| TXNIP | thioredoxin interacting protein | 0.0306939 |
| ENO1 | enolase 1, (alpha) | 0.0297544 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0296738 |
| ASPH | aspartate beta-hydroxylase | 0.0296701 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0292315 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | 0.0292307 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0291656 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0281872 |
| PAPOLA | poly(A) polymerase alpha | 0.0281599 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0277961 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.027604 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0274107 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0273519 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.027308 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0272565 |
| AFDN | afadin, adherens junction formation factor | 0.0272474 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0271541 |
| ZNF292 | zinc finger protein 292 | 0.0270086 |
| TMF1 | TATA element modulatory factor 1 | 0.0265884 |
| KRT8 | keratin 8, type II | 0.0257542 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0255536 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0253698 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0252568 |
| PIGR | polymeric immunoglobulin receptor | 0.025178 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | 0.0246695 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0242754 |
| PHF3 | PHD finger protein 3 | 0.0236155 |
| RPL14 | ribosomal protein L14 | 0.0235465 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0235205 |
| SHROOM3 | shroom family member 3 | 0.023486 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0234502 |
| CDK19 | cyclin-dependent kinase 19 | 0.0234456 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.023439 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | 0.0233561 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0229797 |
| ARF4 | ADP-ribosylation factor 4 | 0.0225902 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0223409 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0223382 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | 0.0222853 |
| ITGA6 | integrin, alpha 6 | 0.0222234 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0221544 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0220793 |
| RPL12 | ribosomal protein L12 | 0.0218665 |
| TPR | translocated promoter region, nuclear basket protein | 0.0217604 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.257948 |
| NPSR1 | neuropeptide S receptor 1 | -0.147667 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | -0.142413 |
| PTMA | prothymosin, alpha | -0.0931426 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0921389 |
| S100A6 | S100 calcium binding protein A6 | -0.0916042 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0847191 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.080009 |
| POTEF | POTE ankyrin domain family, member F | -0.0780821 |
| ACTG1 | actin gamma 1 | -0.0769724 |
| KRT18 | keratin 18, type I | -0.0753585 |
| RPL35A | ribosomal protein L35a | -0.0731521 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0639382 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0623401 |
| TFF1 | trefoil factor 1 | -0.0593809 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0544795 |
| TUBA1B | tubulin, alpha 1b | -0.049427 |
| HMGA1 | high mobility group AT-hook 1 | -0.0485302 |
| TFF3 | trefoil factor 3 (intestinal) | -0.048243 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0479777 |
| KLK10 | kallikrein-related peptidase 10 | -0.0443204 |
| MUC17 | mucin 17, cell surface associated | -0.0430526 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0427149 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0413573 |
| CALB1 | calbindin 1, 28kDa | -0.0394506 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0388155 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0384468 |
| PFN1 | profilin 1 | -0.0384278 |
| RPS6 | ribosomal protein S6 | -0.038333 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0380393 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0369645 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0365389 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0360354 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0353656 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0347694 |
| BMP4 | bone morphogenetic protein 4 | -0.0341782 |
| RPLP0 | ribosomal protein, large, P0 | -0.0335133 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | -0.0334755 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0323417 |
| B4GALNT3 | beta-1,4-N-acetyl-galactosaminyl transferase 3 | -0.0321826 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | -0.0317232 |
| RPS21 | ribosomal protein S21 | -0.0315907 |
| CBX3 | chromobox homolog 3 | -0.0311696 |
| RPS25 | ribosomal protein S25 | -0.0309805 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0307671 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0304634 |
| MT2A | metallothionein 2A | -0.0301898 |
| MYO1E | myosin IE | -0.029908 |
| IER3 | immediate early response 3 | -0.0281036 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0275147 |
| DIAPH1 | diaphanous-related formin 1 | -0.0268171 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0268057 |
| PERP | PERP, TP53 apoptosis effector | -0.0264946 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0262467 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0261864 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0254436 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0254132 |
| TPI1 | triosephosphate isomerase 1 | -0.0253457 |
| PHGR1 | proline/histidine/glycine-rich 1 | -0.0253325 |
| RPS24 | ribosomal protein S24 | -0.0250089 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0249056 |
| RPL9 | ribosomal protein L9 | -0.0247391 |
| LMNA | lamin A/C | -0.0246134 |
| UQCRQ | ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa | -0.0244288 |
| DEK | DEK proto-oncogene | -0.0244172 |
| KRR1 | KRR1, small subunit (SSU) processome component, homolog (yeast) | -0.0239935 |
| FBXO11 | F-box protein 11 | -0.0239014 |
| MGST1 | microsomal glutathione S-transferase 1 | -0.0236397 |
| SVIL | supervillin | -0.0235353 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0234937 |
| S100A10 | S100 calcium binding protein A10 | -0.0233466 |
| KRT19 | keratin 19, type I | -0.0231966 |
| RPL27A | ribosomal protein L27a | -0.0227755 |
| GNAS | GNAS complex locus | -0.0224615 |
| MT1X | metallothionein 1X | -0.0222953 |
| CCND1 | cyclin D1 | -0.0219872 |
| TUBB | tubulin, beta class I | -0.0219142 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0217587 |
| RPS14 | ribosomal protein S14 | -0.0216987 |
| SMAD2 | SMAD family member 2 | -0.0216393 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0211721 |
| MYH14 | myosin, heavy chain 14, non-muscle | -0.0211263 |
| PRDX2 | peroxiredoxin 2 | -0.0211064 |
| RPL36A | ribosomal protein L36a | -0.0204111 |
| CLOCK | clock circadian regulator | -0.0203933 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0203348 |
| RPL15 | ribosomal protein L15 | -0.0202904 |
| RNF217 | ring finger protein 217 | -0.0199071 |
| PGK1 | phosphoglycerate kinase 1 | -0.0198902 |
| EGFR | epidermal growth factor receptor | -0.0198627 |
| PKM | pyruvate kinase, muscle | -0.0197885 |
| LSAMP | limbic system-associated membrane protein | -0.0195552 |
| FTL | ferritin, light polypeptide | -0.0193291 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0193235 |
| CSTB | cystatin B (stefin B) | -0.0193178 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0192394 |
| PA2G4 | proliferation-associated 2G4, 38kDa | -0.0191723 |
| TPM4 | tropomyosin 4 | -0.019128 |
| VCAN | versican | -0.0188517 |
| ASTN2 | astrotactin 2 | -0.0186139 |
