| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Apalutamide perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Apalutamide_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DST | dystonin | 0.127175 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.110346 |
| CD44 | CD44 molecule (Indian blood group) | 0.0781334 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0775168 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0754986 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0710416 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0697762 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0694318 |
| TP63 | tumor protein p63 | 0.065013 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0619857 |
| VIM | vimentin | 0.0606901 |
| EHBP1 | EH domain binding protein 1 | 0.0575918 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0574887 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0531273 |
| CENPF | centromere protein F, 350/400kDa | 0.0530118 |
| PTMA | prothymosin, alpha | 0.052533 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0520547 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0506972 |
| LDHA | lactate dehydrogenase A | 0.0502625 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0495669 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0481708 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0457687 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.045121 |
| EXOC4 | exocyst complex component 4 | 0.0436982 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0436305 |
| RUNX1 | runt-related transcription factor 1 | 0.0431735 |
| RAD51B | RAD51 paralog B | 0.0417844 |
| FMNL2 | formin-like 2 | 0.0416174 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.04018 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0396932 |
| RIGI | RNA sensor RIG-I | 0.0387558 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0379193 |
| DPYD | dihydropyrimidine dehydrogenase | 0.037801 |
| PTK2 | protein tyrosine kinase 2 | 0.036637 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0364696 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0363633 |
| ENO1 | enolase 1, (alpha) | 0.035462 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0354008 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | 0.035372 |
| APP | amyloid beta (A4) precursor protein | 0.0353145 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0351105 |
| FNIP1 | folliculin interacting protein 1 | 0.035081 |
| CADM2 | cell adhesion molecule 2 | 0.0347946 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.034739 |
| TNS3 | tensin 3 | 0.03435 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0340437 |
| HDAC9 | histone deacetylase 9 | 0.0334032 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0331082 |
| CANX | calnexin | 0.0325381 |
| KLF6 | Kruppel-like factor 6 | 0.0324352 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0322418 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0320295 |
| RAI1 | retinoic acid induced 1 | 0.0312756 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0312417 |
| RNF213 | ring finger protein 213 | 0.0307273 |
| EFNA5 | ephrin-A5 | 0.0305744 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0304377 |
| CFAP299 | cilia and flagella associated protein 299 | 0.0300724 |
| SET | SET nuclear proto-oncogene | 0.0296568 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0293284 |
| SLK | STE20-like kinase | 0.0292498 |
| RPS3 | ribosomal protein S3 | 0.0291723 |
| DOCK11 | dedicator of cytokinesis 11 | 0.028797 |
| RPL26 | ribosomal protein L26 | 0.0285502 |
| SMYD3 | SET and MYND domain containing 3 | 0.0284493 |
| MYOF | myoferlin | 0.0279268 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0277309 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | 0.0276117 |
| SP100 | SP100 nuclear antigen | 0.027044 |
| ANXA2 | annexin A2 | 0.0268842 |
| YEATS2 | YEATS domain containing 2 | 0.0267326 |
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 | 0.0267091 |
| PODXL | podocalyxin-like | 0.0265923 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0256226 |
| EPHA4 | EPH receptor A4 | 0.0253488 |
| CDK6 | cyclin-dependent kinase 6 | 0.0252734 |
| PRELID2 | PRELI domain containing 2 | 0.0251028 |
| AHNAK | AHNAK nucleoprotein | 0.0249436 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.024474 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0243089 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.024149 |
| MKI67 | marker of proliferation Ki-67 | 0.0241299 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0237805 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0237346 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0232222 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0227765 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0227184 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0223734 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0222204 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0222114 |
| FNBP4 | formin binding protein 4 | 0.0218676 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0217454 |
| GOLGB1 | golgin B1 | 0.0217326 |
| PDE10A | phosphodiesterase 10A | 0.0215325 |
| STAG2 | stromal antigen 2 | 0.0213495 |
| PLK2 | polo-like kinase 2 | 0.0211933 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0210229 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0208594 |
| CALR | calreticulin | 0.0206699 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0204698 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.161706 |
| MT2A | metallothionein 2A | -0.0989586 |
| TMSB10 | thymosin beta 10 | -0.0537791 |
| MT1X | metallothionein 1X | -0.0523899 |
| FTL | ferritin, light polypeptide | -0.0465865 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0419084 |
| POTEF | POTE ankyrin domain family, member F | -0.040069 |
| MT1E | metallothionein 1E | -0.0365344 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0346122 |
| RPL35A | ribosomal protein L35a | -0.0301069 |
| HMGA1 | high mobility group AT-hook 1 | -0.0283349 |
| EGR1 | early growth response 1 | -0.0273009 |
| RPLP1 | ribosomal protein, large, P1 | -0.0239827 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0214745 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0190603 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | -0.0188749 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0188028 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0179746 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | -0.0169099 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.0166127 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | -0.016445 |
| S100A6 | S100 calcium binding protein A6 | -0.0157983 |
| RPL28 | ribosomal protein L28 | -0.0157741 |
| TXNRD1 | thioredoxin reductase 1 | -0.0157432 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0154641 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0153964 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0147804 |
| FOSL1 | FOS-like antigen 1 | -0.0146398 |
| S100A10 | S100 calcium binding protein A10 | -0.0144776 |
| ANGPTL4 | angiopoietin-like 4 | -0.013754 |
| TMEM41B | transmembrane protein 41B | -0.0135222 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0135113 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0128869 |
| S100A11 | S100 calcium binding protein A11 | -0.0124296 |
| TAPBP | TAP binding protein (tapasin) | -0.0122889 |
| AREG | amphiregulin | -0.0115144 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0114935 |
| UPP1 | uridine phosphorylase 1 | -0.0113485 |
| WDR45B | WD repeat domain 45B | -0.0112002 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0108219 |
| HMOX1 | heme oxygenase 1 | -0.0102849 |
| IER3 | immediate early response 3 | -0.0102615 |
| RPLP2 | ribosomal protein, large, P2 | -0.0102043 |
| PRDX1 | peroxiredoxin 1 | -0.00961463 |
| RPL39 | ribosomal protein L39 | -0.00943083 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.00928452 |
| RPS20 | ribosomal protein S20 | -0.00909668 |
| PER1 | period circadian clock 1 | -0.00862781 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.00855799 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.00827892 |
| RPS25 | ribosomal protein S25 | -0.0082131 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.00815646 |
| RPS5 | ribosomal protein S5 | -0.008134 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.00796472 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.00763971 |
| PKM | pyruvate kinase, muscle | -0.00761754 |
| SEPTIN7 | septin 7 | -0.00752608 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.00730765 |
| LENG8 | leukocyte receptor cluster (LRC) member 8 | -0.00711027 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | -0.00704598 |
| UBC | ubiquitin C | -0.0070252 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.00699265 |
| CKS2 | CDC28 protein kinase regulatory subunit 2 | -0.00696847 |
| RPLP0 | ribosomal protein, large, P0 | -0.00686932 |
| CDCP1 | CUB domain containing protein 1 | -0.00672058 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.00669516 |
| KCNK6 | potassium channel, two pore domain subfamily K, member 6 | -0.00664141 |
| LHX1 | LIM homeobox 1 | -0.00648386 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.00644474 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | -0.00642889 |
| KCMF1 | potassium channel modulatory factor 1 | -0.0064269 |
| RPS24 | ribosomal protein S24 | -0.00623207 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.00613014 |
| ERCC1 | excision repair cross-complementation group 1 | -0.00600739 |
| ACTG1 | actin gamma 1 | -0.00599418 |
| RPS16 | ribosomal protein S16 | -0.00596622 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.00586655 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | -0.0058558 |
| LRP10 | low density lipoprotein receptor-related protein 10 | -0.00585096 |
| DPP9 | dipeptidyl-peptidase 9 | -0.00584983 |
| CCNL1 | cyclin L1 | -0.00584568 |
| TPD52 | tumor protein D52 | -0.00583584 |
| DEPP1 | DEPP autophagy regulator 1 | -0.00579201 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | -0.00576913 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) | -0.00575412 |
| ZGPAT | zinc finger, CCCH-type with G patch domain | -0.00574237 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.00573226 |
| SEC61G | Sec61 gamma subunit | -0.00570681 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.00570422 |
| NDRG1 | N-myc downstream regulated 1 | -0.00568794 |
| ABI1 | abl-interactor 1 | -0.00566049 |
| GUK1 | guanylate kinase 1 | -0.00559875 |
| DNTTIP1 | deoxynucleotidyltransferase, terminal, interacting protein 1 | -0.00553474 |
| UBA52 | ubiquitin A-52 residue ribosomal protein fusion product 1 | -0.00546315 |
| INSIG1 | insulin induced gene 1 | -0.00538308 |
| RPS28 | ribosomal protein S28 | -0.00537649 |
| RPL27 | ribosomal protein L27 | -0.00531916 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.00524224 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.00520286 |
| RPL31 | ribosomal protein L31 | -0.00517562 |
