| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Apalutamide perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Apalutamide_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | 0.125768 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0985029 |
| PDE10A | phosphodiesterase 10A | 0.0956181 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0955731 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0928506 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0810624 |
| EGFR | epidermal growth factor receptor | 0.0792929 |
| FAT1 | FAT atypical cadherin 1 | 0.0777238 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0765911 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0761995 |
| EFNA5 | ephrin-A5 | 0.0728875 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0719723 |
| NDRG1 | N-myc downstream regulated 1 | 0.071965 |
| FLNB | filamin B, beta | 0.0706206 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0699337 |
| EHBP1 | EH domain binding protein 1 | 0.0696873 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0695399 |
| MEF2A | myocyte enhancer factor 2A | 0.0691442 |
| PHF21A | PHD finger protein 21A | 0.0653653 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0651572 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0634601 |
| NAV2 | neuron navigator 2 | 0.0631115 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0619573 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0601326 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0598517 |
| OGA | O-GlcNAcase | 0.0556107 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0553351 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0541678 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0541113 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0512846 |
| PRELID2 | PRELI domain containing 2 | 0.0512787 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0509955 |
| XPO1 | exportin 1 | 0.0498858 |
| BRD4 | bromodomain containing 4 | 0.0494694 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0477431 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0474741 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0472315 |
| FNDC3B | fibronectin type III domain containing 3B | 0.046992 |
| VCL | vinculin | 0.0466173 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.0463591 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0461485 |
| ATXN1 | ataxin 1 | 0.0454282 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0448072 |
| LAMB3 | laminin, beta 3 | 0.0431715 |
| CD44 | CD44 molecule (Indian blood group) | 0.0427658 |
| TJP1 | tight junction protein 1 | 0.0427052 |
| CFDP1 | craniofacial development protein 1 | 0.042555 |
| TXNRD1 | thioredoxin reductase 1 | 0.0421576 |
| ZNF292 | zinc finger protein 292 | 0.0420815 |
| MAPK8 | mitogen-activated protein kinase 8 | 0.0415531 |
| ENO1 | enolase 1, (alpha) | 0.041433 |
| AHNAK | AHNAK nucleoprotein | 0.0406253 |
| SMYD3 | SET and MYND domain containing 3 | 0.0401975 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0395202 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 0.0369864 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.0360692 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0359234 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0354421 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0354248 |
| ITSN2 | intersectin 2 | 0.0353785 |
| RPL32 | ribosomal protein L32 | 0.0351094 |
| CLTC | clathrin, heavy chain (Hc) | 0.035061 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.0349943 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0347338 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0346646 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0343096 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0341623 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0339663 |
| ANLN | anillin, actin binding protein | 0.0334188 |
| SP100 | SP100 nuclear antigen | 0.0332921 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0330838 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.033063 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0328219 |
| BBX | bobby sox homolog (Drosophila) | 0.0327794 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.032643 |
| FAM13A | family with sequence similarity 13, member A | 0.0320414 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0318601 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0318173 |
| YAP1 | Yes-associated protein 1 | 0.0315279 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0312659 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0310321 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0307801 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0301606 |
| RACK1 | receptor for activated C kinase 1 | 0.030152 |
| ARF4 | ADP-ribosylation factor 4 | 0.0299038 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0290436 |
| MED13L | mediator complex subunit 13-like | 0.028451 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0275654 |
| ATP11A | ATPase, class VI, type 11A | 0.0272659 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0270556 |
| MYOF | myoferlin | 0.0268286 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0265843 |
| GOLGA4 | golgin A4 | 0.0260401 |
| PGK1 | phosphoglycerate kinase 1 | 0.0259559 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | 0.0259548 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0258641 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0257431 |
| DENND4C | DENN/MADD domain containing 4C | 0.0254792 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0248951 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0248754 |
| Symbol | Name | Standardized Value |
|---|---|---|
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.105147 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0961469 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.085316 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0829657 |
| RPL35A | ribosomal protein L35a | -0.0725989 |
| ARF1 | ADP-ribosylation factor 1 | -0.068865 |
| CYRIB | CYFIP related Rac1 interactor B | -0.0682521 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.067239 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0664016 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.0663887 |
| FTL | ferritin, light polypeptide | -0.0654729 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0640296 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0637093 |
| LMO7 | LIM domain 7 | -0.0613331 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0601923 |
| RPLP1 | ribosomal protein, large, P1 | -0.0588149 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0587104 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0586674 |
| TMSB10 | thymosin beta 10 | -0.0583396 |
| TAOK3 | TAO kinase 3 | -0.0579878 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0578135 |
| VMP1 | vacuole membrane protein 1 | -0.056974 |
| INTS6 | integrator complex subunit 6 | -0.0560444 |
| FNIP1 | folliculin interacting protein 1 | -0.0545785 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0539035 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0538606 |
| DENND1A | DENN/MADD domain containing 1A | -0.0534622 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0530772 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | -0.0523516 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0500199 |
| PTK2 | protein tyrosine kinase 2 | -0.049828 |
| MYO1E | myosin IE | -0.049817 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0494402 |
| MCL1 | myeloid cell leukemia 1 | -0.0488538 |
| POTEF | POTE ankyrin domain family, member F | -0.0485168 |
| AFF1 | AF4/FMR2 family, member 1 | -0.0482138 |
| ANXA2 | annexin A2 | -0.0478858 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0477414 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.047706 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0475154 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0474493 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.046994 |
| SEPTIN7 | septin 7 | -0.0466595 |
| MYO6 | myosin VI | -0.0465299 |
| RPL8 | ribosomal protein L8 | -0.0464473 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | -0.0462398 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.045543 |
| GPC6 | glypican 6 | -0.0443834 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0441648 |
| KLF6 | Kruppel-like factor 6 | -0.0421033 |
| ZNF207 | zinc finger protein 207 | -0.0415901 |
| PRKCA | protein kinase C, alpha | -0.0408611 |
| COPA | coatomer protein complex, subunit alpha | -0.0406058 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0404287 |
| MT2A | metallothionein 2A | -0.040416 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0403937 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0397247 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0393814 |
| SVIL | supervillin | -0.0392141 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0392108 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0383921 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0381377 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.037888 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0378069 |
| S100A10 | S100 calcium binding protein A10 | -0.0370906 |
| SRPK2 | SRSF protein kinase 2 | -0.0369708 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0369102 |
| DGKD | diacylglycerol kinase, delta 130kDa | -0.036517 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.035922 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0358037 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0355258 |
| ILRUN | inflammation and lipid regulator with UBA-like and NBR1-like domains | -0.0355035 |
| CUL4A | cullin 4A | -0.0354846 |
| CERS6 | ceramide synthase 6 | -0.0353707 |
| GOLGB1 | golgin B1 | -0.0352784 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0344816 |
| SETD5 | SET domain containing 5 | -0.0341369 |
| TIAL1 | TIA1 cytotoxic granule-associated RNA binding protein-like 1 | -0.0341216 |
| NCOA3 | nuclear receptor coactivator 3 | -0.0340125 |
| RORA | RAR-related orphan receptor A | -0.0334952 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0334014 |
| MSI2 | musashi RNA-binding protein 2 | -0.0333739 |
| XPR1 | xenotropic and polytropic retrovirus receptor 1 | -0.0331203 |
| USP53 | ubiquitin specific peptidase 53 | -0.0330277 |
| MATR3 | matrin 3 | -0.0328385 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0326627 |
| NCOR1 | nuclear receptor corepressor 1 | -0.032511 |
| PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha | -0.0324178 |
| SPATS2 | spermatogenesis associated, serine-rich 2 | -0.0320964 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.032043 |
| SMAD2 | SMAD family member 2 | -0.0316998 |
| HELZ | helicase with zinc finger | -0.0316034 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0308883 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0307797 |
| DST | dystonin | -0.0306654 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0306255 |
| RPS4X | ribosomal protein S4, X-linked | -0.0302599 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.030203 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.029519 |
| RLF | rearranged L-myc fusion | -0.0294097 |
