| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Apalutamide perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Apalutamide_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.325684 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.175751 |
| LDHA | lactate dehydrogenase A | 0.119669 |
| BICC1 | BicC family RNA binding protein 1 | 0.111445 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.111079 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.101736 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0997361 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0951679 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0900228 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0895802 |
| DST | dystonin | 0.0820534 |
| VCAN | versican | 0.0818365 |
| ANXA2 | annexin A2 | 0.0750513 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0737813 |
| OPTN | optineurin | 0.0730834 |
| VCL | vinculin | 0.0717932 |
| RTN4 | reticulon 4 | 0.0710212 |
| MSN | moesin | 0.0679502 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0672939 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0652953 |
| THBS1 | thrombospondin 1 | 0.064496 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0622231 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0621096 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0613851 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0604254 |
| VMP1 | vacuole membrane protein 1 | 0.0575955 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0571386 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0569435 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0555853 |
| MX1 | MX dynamin-like GTPase 1 | 0.0555544 |
| SP100 | SP100 nuclear antigen | 0.0543479 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0541568 |
| RIGI | RNA sensor RIG-I | 0.0539248 |
| TXNIP | thioredoxin interacting protein | 0.0533881 |
| RBM39 | RNA binding motif protein 39 | 0.0512269 |
| GOLGB1 | golgin B1 | 0.0494022 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0481086 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0462239 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0438725 |
| PCBP2 | poly(rC) binding protein 2 | 0.0419213 |
| AHR | aryl hydrocarbon receptor | 0.0415693 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0399563 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0398743 |
| RNF213 | ring finger protein 213 | 0.0393751 |
| HDAC9 | histone deacetylase 9 | 0.0389665 |
| FLNA | filamin A, alpha | 0.0388457 |
| OGA | O-GlcNAcase | 0.0383059 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0380312 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0369102 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0367115 |
| PRELID2 | PRELI domain containing 2 | 0.0366253 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0364388 |
| SFTPA2 | surfactant protein A2 | 0.0361243 |
| CEP250 | centrosomal protein 250kDa | 0.0361201 |
| BRD2 | bromodomain containing 2 | 0.0360034 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0358079 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | 0.0355251 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0350309 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0349815 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0349509 |
| CALD1 | caldesmon 1 | 0.0340178 |
| MYOF | myoferlin | 0.0339992 |
| ARF4 | ADP-ribosylation factor 4 | 0.0338362 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0331593 |
| MKI67 | marker of proliferation Ki-67 | 0.0330199 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0329837 |
| PHF3 | PHD finger protein 3 | 0.0329285 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0328902 |
| CUL4B | cullin 4B | 0.0327764 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0321929 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.03183 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0317403 |
| RPS4X | ribosomal protein S4, X-linked | 0.031703 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0315252 |
| CLIC4 | chloride intracellular channel 4 | 0.031501 |
| ARRDC3 | arrestin domain containing 3 | 0.0314858 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0312881 |
| GLIPR1 | GLI pathogenesis-related 1 | 0.0310204 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0307789 |
| TNS3 | tensin 3 | 0.030776 |
| SQSTM1 | sequestosome 1 | 0.0305143 |
| CENPF | centromere protein F, 350/400kDa | 0.0302269 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0301873 |
| VEGFA | vascular endothelial growth factor A | 0.0301241 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.0296812 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0294572 |
| PMP22 | peripheral myelin protein 22 | 0.0292363 |
| WDR1 | WD repeat domain 1 | 0.0290592 |
| NABP1 | nucleic acid binding protein 1 | 0.0289416 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0286084 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0282496 |
| YBX1 | Y box binding protein 1 | 0.0280134 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0279848 |
| TNNC1 | troponin C type 1 (slow) | 0.027849 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0275561 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0274673 |
| LAMP2 | lysosomal-associated membrane protein 2 | 0.0267893 |
| PDE5A | phosphodiesterase 5A, cGMP-specific | 0.0266053 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.0265287 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0265143 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FRMD4A | FERM domain containing 4A | -0.159696 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.116085 |
| IER3 | immediate early response 3 | -0.114852 |
| TMSB10 | thymosin beta 10 | -0.11454 |
| VIM | vimentin | -0.114341 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.103409 |
| CDH13 | cadherin 13 | -0.0977248 |
| GLIS3 | GLIS family zinc finger 3 | -0.089106 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0763789 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0737812 |
| HMGA2 | high mobility group AT-hook 2 | -0.0719839 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0630424 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0627569 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0607162 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | -0.0597997 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0563901 |
| TMSB4X | thymosin beta 4, X-linked | -0.0555924 |
| FTL | ferritin, light polypeptide | -0.0555074 |
| PDE10A | phosphodiesterase 10A | -0.0528379 |
| STC1 | stanniocalcin 1 | -0.0485078 |
| RPLP2 | ribosomal protein, large, P2 | -0.0458358 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0439163 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0437941 |
| NDRG1 | N-myc downstream regulated 1 | -0.043754 |
| EFNA5 | ephrin-A5 | -0.042824 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0424538 |
| HLA-B | major histocompatibility complex, class I, B | -0.0424089 |
| INHBA | inhibin, beta A | -0.0414407 |
| CLMP | CXADR-like membrane protein | -0.0412262 |
| ATP13A3 | ATPase type 13A3 | -0.0412137 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0396496 |
| HLA-A | major histocompatibility complex, class I, A | -0.0386575 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0381741 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0379852 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.0378576 |
| AHNAK | AHNAK nucleoprotein | -0.0378412 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0374397 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.037045 |
| PPARD | peroxisome proliferator-activated receptor delta | -0.0354488 |
| RPS19 | ribosomal protein S19 | -0.0352883 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0348005 |
| EGFR | epidermal growth factor receptor | -0.0340994 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.0338586 |
| RPL35A | ribosomal protein L35a | -0.0336872 |
| BNC2 | basonuclin 2 | -0.0333955 |
| GPC6 | glypican 6 | -0.0333582 |
| COL6A2 | collagen, type VI, alpha 2 | -0.033034 |
| RPS23 | ribosomal protein S23 | -0.0328659 |
| TMEM132D | transmembrane protein 132D | -0.03286 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0327128 |
| RPL37A | ribosomal protein L37a | -0.0326748 |
| FMNL2 | formin-like 2 | -0.0322205 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0320645 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | -0.0317902 |
| DIAPH2 | diaphanous-related formin 2 | -0.0316676 |
| CTSD | cathepsin D | -0.0309711 |
| RPS21 | ribosomal protein S21 | -0.030582 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0301604 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0300694 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.029726 |
| LOX | lysyl oxidase | -0.0294695 |
| RPL19 | ribosomal protein L19 | -0.0293395 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0288374 |
| MT2A | metallothionein 2A | -0.0287386 |
| RPL23 | ribosomal protein L23 | -0.0284656 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.0283766 |
| COL1A1 | collagen, type I, alpha 1 | -0.0282185 |
| PGK1 | phosphoglycerate kinase 1 | -0.0277141 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0275646 |
| NRN1 | neuritin 1 | -0.0273599 |
| FOXP1 | forkhead box P1 | -0.0273241 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | -0.0267172 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0264812 |
| SEPTIN9 | septin 9 | -0.0264542 |
| RPS24 | ribosomal protein S24 | -0.0263021 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0261587 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.025602 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0254304 |
| SLC35F3 | solute carrier family 35, member F3 | -0.025264 |
| ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif, 12 | -0.0251106 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0249342 |
| CCBE1 | collagen and calcium binding EGF domains 1 | -0.0240767 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0239543 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0239418 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | -0.0237611 |
| DENND5B | DENN/MADD domain containing 5B | -0.0233698 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0233038 |
| PCBP3 | poly(rC) binding protein 3 | -0.0231185 |
| RUNX1 | runt-related transcription factor 1 | -0.0229731 |
| CUX1 | cut-like homeobox 1 | -0.0229701 |
| GNAS | GNAS complex locus | -0.0229556 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0228781 |
| DENND2A | DENN/MADD domain containing 2A | -0.0225187 |
| RPS27A | ribosomal protein S27a | -0.0224817 |
| CNTN6 | contactin 6 | -0.0222959 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0222945 |
| TENM2 | teneurin transmembrane protein 2 | -0.0221881 |
| CD109 | CD109 molecule | -0.0221695 |
| PTMA | prothymosin, alpha | -0.0220969 |
| RPL32 | ribosomal protein L32 | -0.0220906 |
