| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Apalutamide perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Apalutamide_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.174679 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.144169 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.101891 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0969832 |
| B2M | beta-2-microglobulin | 0.0847823 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0847199 |
| VIM | vimentin | 0.0786137 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0781241 |
| MT2A | metallothionein 2A | 0.0692134 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0597949 |
| FN1 | fibronectin 1 | 0.0565185 |
| CD44 | CD44 molecule (Indian blood group) | 0.0558326 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0549852 |
| LOX | lysyl oxidase | 0.0545618 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0530623 |
| ENO1 | enolase 1, (alpha) | 0.0519092 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0507839 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0496431 |
| MAP1B | microtubule-associated protein 1B | 0.0475172 |
| LOXL2 | lysyl oxidase-like 2 | 0.0470158 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.046493 |
| HLA-B | major histocompatibility complex, class I, B | 0.0436909 |
| PRSS23 | protease, serine, 23 | 0.0435281 |
| COL5A1 | collagen, type V, alpha 1 | 0.0416996 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0409178 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.040014 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0389089 |
| CDH13 | cadherin 13 | 0.0372321 |
| CALU | calumenin | 0.0368691 |
| COL1A1 | collagen, type I, alpha 1 | 0.0365295 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.0364502 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.0347934 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0346896 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0336282 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0332318 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0329765 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0323289 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0315191 |
| ECE1 | endothelin converting enzyme 1 | 0.0312449 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0310121 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0303927 |
| LDHA | lactate dehydrogenase A | 0.0297727 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0295441 |
| ARRDC3 | arrestin domain containing 3 | 0.0292621 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0287589 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0286939 |
| TMSB10 | thymosin beta 10 | 0.02808 |
| PGK1 | phosphoglycerate kinase 1 | 0.027754 |
| ANXA2 | annexin A2 | 0.0272225 |
| FMNL2 | formin-like 2 | 0.0268785 |
| STC1 | stanniocalcin 1 | 0.0265414 |
| PTMA | prothymosin, alpha | 0.0260991 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0260208 |
| NRP1 | neuropilin 1 | 0.0257896 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0256238 |
| SMAD3 | SMAD family member 3 | 0.0255746 |
| HMGA2 | high mobility group AT-hook 2 | 0.0254515 |
| FNDC3B | fibronectin type III domain containing 3B | 0.025375 |
| ZNF395 | zinc finger protein 395 | 0.025266 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0243921 |
| RAI14 | retinoic acid induced 14 | 0.0241648 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | 0.0239091 |
| EGFR | epidermal growth factor receptor | 0.0236815 |
| TMEM165 | transmembrane protein 165 | 0.023634 |
| GLIS3 | GLIS family zinc finger 3 | 0.0233184 |
| HLA-C | major histocompatibility complex, class I, C | 0.0231832 |
| MAP4 | microtubule-associated protein 4 | 0.0230185 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0227576 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0227346 |
| AHNAK | AHNAK nucleoprotein | 0.0224699 |
| CALR | calreticulin | 0.0223864 |
| TPM4 | tropomyosin 4 | 0.0216882 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0216727 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 | 0.0215845 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0214579 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0213739 |
| CDK6 | cyclin-dependent kinase 6 | 0.0213633 |
| ASPH | aspartate beta-hydroxylase | 0.0210272 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0209892 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | 0.0209697 |
| DIAPH3 | diaphanous-related formin 3 | 0.0205483 |
| POTEF | POTE ankyrin domain family, member F | 0.0205335 |
| COL1A2 | collagen, type I, alpha 2 | 0.0204962 |
| GOLGB1 | golgin B1 | 0.0200741 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0199165 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0198341 |
| CLIC4 | chloride intracellular channel 4 | 0.019745 |
| PRKCA | protein kinase C, alpha | 0.019602 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0195718 |
| COL6A1 | collagen, type VI, alpha 1 | 0.0194275 |
| TPM1 | tropomyosin 1 (alpha) | 0.0193376 |
| ANLN | anillin, actin binding protein | 0.0188702 |
| HDLBP | high density lipoprotein binding protein | 0.0188079 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0187573 |
| PKM | pyruvate kinase, muscle | 0.0187087 |
| CALD1 | caldesmon 1 | 0.0186938 |
| IL6 | interleukin 6 | 0.0186313 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0184768 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0182878 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0180263 |
| Symbol | Name | Standardized Value |
|---|---|---|
| WSB1 | WD repeat and SOCS box containing 1 | -0.021244 |
| PDE10A | phosphodiesterase 10A | -0.0155564 |
| SEC24B | SEC24 family member B | -0.0151635 |
| SRP54 | signal recognition particle 54kDa | -0.0144607 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | -0.0140888 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.013317 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0132132 |
| SYT1 | synaptotagmin I | -0.0130369 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0130209 |
| FBXO34 | F-box protein 34 | -0.0126939 |
| CCNY | cyclin Y | -0.0125948 |
| LARP1 | La ribonucleoprotein domain family, member 1 | -0.0125751 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0124379 |
| NFX1 | nuclear transcription factor, X-box binding 1 | -0.0122851 |
| NUP214 | nucleoporin 214kDa | -0.0120304 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0119888 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0119872 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | -0.0119843 |
| C1D | C1D nuclear receptor corepressor | -0.0118559 |
| NUP58 | nucleoporin 58 | -0.0117044 |
| RAB10 | RAB10, member RAS oncogene family | -0.0115962 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0115558 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0115431 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0113289 |
| R3HDM1 | R3H domain containing 1 | -0.0112817 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.011211 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0109745 |
| TCERG1 | transcription elongation regulator 1 | -0.0109684 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0109619 |
| IWS1 | IWS1 homolog (S. cerevisiae) | -0.0109222 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0108374 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0107879 |
| MGRN1 | mahogunin ring finger 1, E3 ubiquitin protein ligase | -0.0107572 |
| NCOA3 | nuclear receptor coactivator 3 | -0.0107315 |
| KIF16B | kinesin family member 16B | -0.0107268 |
| HELZ | helicase with zinc finger | -0.010679 |
| EXOC5 | exocyst complex component 5 | -0.0106115 |
| AKAP10 | A kinase (PRKA) anchor protein 10 | -0.0105694 |
| ANKRD33B | ankyrin repeat domain 33B | -0.0105123 |
| ATF6 | activating transcription factor 6 | -0.0105056 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0104641 |
| IQCB1 | IQ motif containing B1 | -0.010446 |
| CDS2 | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 | -0.0103814 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | -0.010323 |
| RBM33 | RNA binding motif protein 33 | -0.0101932 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0101562 |
| TOP1 | topoisomerase (DNA) I | -0.0101264 |
| NRF1 | nuclear respiratory factor 1 | -0.0101054 |
| PDSS2 | prenyl (decaprenyl) diphosphate synthase, subunit 2 | -0.0100986 |
| GDI2 | GDP dissociation inhibitor 2 | -0.0100985 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | -0.010056 |
| RAP1A | RAP1A, member of RAS oncogene family | -0.00998804 |
| NAA50 | N(alpha)-acetyltransferase 50, NatE catalytic subunit | -0.00998271 |
| CPSF6 | cleavage and polyadenylation specific factor 6, 68kDa | -0.00995083 |
| HEG1 | heart development protein with EGF-like domains 1 | -0.00991714 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.00988846 |
| CCNYL1 | cyclin Y-like 1 | -0.00984856 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.00981628 |
| OGA | O-GlcNAcase | -0.00980995 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 | -0.00978467 |
| SUZ12 | SUZ12 polycomb repressive complex 2 subunit | -0.00974712 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.00964373 |
| LARP1B | La ribonucleoprotein domain family, member 1B | -0.00961712 |
| PKD1 | polycystic kidney disease 1 (autosomal dominant) | -0.00959372 |
| OSBPL2 | oxysterol binding protein-like 2 | -0.00957863 |
| CPNE1 | copine I | -0.00956125 |
| CTNNBL1 | catenin, beta like 1 | -0.00955861 |
| PPME1 | protein phosphatase methylesterase 1 | -0.00954335 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.00954139 |
| RCOR1 | REST corepressor 1 | -0.00949758 |
| CYTH1 | cytohesin 1 | -0.00945788 |
| RAB6A | RAB6A, member RAS oncogene family | -0.00945023 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | -0.00940788 |
| SMYD3 | SET and MYND domain containing 3 | -0.00938561 |
| LMNA | lamin A/C | -0.00936534 |
| KIZ | kizuna centrosomal protein | -0.00933025 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.00926914 |
| RGS17 | regulator of G-protein signaling 17 | -0.00925189 |
| FNBP1L | formin binding protein 1-like | -0.00924155 |
| RNF115 | ring finger protein 115 | -0.00923807 |
| TJAP1 | tight junction associated protein 1 (peripheral) | -0.009237 |
| CAPRIN2 | caprin family member 2 | -0.00923478 |
| NBAS | neuroblastoma amplified sequence | -0.00922585 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | -0.00921773 |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 | -0.00919186 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.00917633 |
| LASP1 | LIM and SH3 protein 1 | -0.00917136 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | -0.00911993 |
| OTULIN | OTU deubiquitinase with linear linkage specificity | -0.00909314 |
| NABP1 | nucleic acid binding protein 1 | -0.00907518 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 | -0.0090669 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.00905029 |
| SNX33 | sorting nexin 33 | -0.00901804 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.00901172 |
| NXN | nucleoredoxin | -0.00900024 |
| EPB41 | erythrocyte membrane protein band 4.1 | -0.00899953 |
| BCAR1 | breast cancer anti-estrogen resistance 1 | -0.0089913 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.00898557 |
| GARRE1 | granule associated Rac and RHOG effector 1 | -0.00895603 |
| KALRN | kalirin, RhoGEF kinase | -0.00895554 |
