| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Apalutamide perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Apalutamide_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0886503 |
| CENPF | centromere protein F, 350/400kDa | 0.0836708 |
| ZNF292 | zinc finger protein 292 | 0.0602259 |
| TPX2 | TPX2, microtubule-associated | 0.0539983 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0539109 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0536958 |
| RBM39 | RNA binding motif protein 39 | 0.0519948 |
| MKI67 | marker of proliferation Ki-67 | 0.0517908 |
| YAP1 | Yes-associated protein 1 | 0.0497243 |
| ANLN | anillin, actin binding protein | 0.0490825 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0490044 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0487829 |
| NUP58 | nucleoporin 58 | 0.0484043 |
| GOLGA4 | golgin A4 | 0.0471459 |
| SGO2 | shugoshin 2 | 0.046493 |
| DIAPH3 | diaphanous-related formin 3 | 0.0459726 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0454439 |
| APOLD1 | apolipoprotein L domain containing 1 | 0.0449349 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0439948 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0436528 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0419769 |
| CLTC | clathrin, heavy chain (Hc) | 0.0402218 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0362112 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0361928 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0355396 |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) | 0.0353509 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0345406 |
| DERA | deoxyribose-phosphate aldolase (putative) | 0.0341931 |
| CEP250 | centrosomal protein 250kDa | 0.033529 |
| CKAP2 | cytoskeleton associated protein 2 | 0.0331741 |
| ECT2 | epithelial cell transforming 2 | 0.0330862 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0328926 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0324795 |
| COG5 | component of oligomeric golgi complex 5 | 0.0322242 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0319262 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0318241 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0310659 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0303638 |
| XPO1 | exportin 1 | 0.0303548 |
| KIF5B | kinesin family member 5B | 0.0302952 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0298721 |
| TXNRD1 | thioredoxin reductase 1 | 0.0293665 |
| ATF7IP | activating transcription factor 7 interacting protein | 0.0291573 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0289858 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0289556 |
| PAPOLA | poly(A) polymerase alpha | 0.0287982 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | 0.0285995 |
| NCOA6 | nuclear receptor coactivator 6 | 0.027969 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0278063 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.027718 |
| YBX3 | Y box binding protein 3 | 0.0276564 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0275801 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0273642 |
| IPO7 | importin 7 | 0.0272989 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.027284 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0271551 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0269047 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | 0.0264704 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0262694 |
| MED13L | mediator complex subunit 13-like | 0.0260813 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0257657 |
| PUM2 | pumilio RNA-binding family member 2 | 0.025691 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | 0.025635 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0255898 |
| AHCTF1 | AT hook containing transcription factor 1 | 0.025501 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0254493 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0253138 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0252494 |
| FNIP1 | folliculin interacting protein 1 | 0.0251775 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0251227 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0250595 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0241846 |
| ANXA2 | annexin A2 | 0.0239813 |
| DDX46 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 | 0.0239532 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.023845 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0237483 |
| CEP152 | centrosomal protein 152kDa | 0.0235837 |
| NUP98 | nucleoporin 98kDa | 0.0235128 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0234621 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0234522 |
| LDHB | lactate dehydrogenase B | 0.0234157 |
| OLA1 | Obg-like ATPase 1 | 0.0233799 |
| HJURP | Holliday junction recognition protein | 0.0232904 |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase | 0.0232495 |
| GOLT1B | golgi transport 1B | 0.0232455 |
| ATP13A3 | ATPase type 13A3 | 0.0231022 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0230677 |
| PCBP2 | poly(rC) binding protein 2 | 0.0229689 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0229114 |
| SMYD3 | SET and MYND domain containing 3 | 0.0228701 |
| PRC1 | protein regulator of cytokinesis 1 | 0.0225283 |
| GOLGB1 | golgin B1 | 0.0224179 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0220204 |
| KIAA1328 | KIAA1328 | 0.0219935 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0218181 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0216404 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0215052 |
| SPAG5 | sperm associated antigen 5 | 0.0214388 |
| ACIN1 | apoptotic chromatin condensation inducer 1 | 0.0213966 |
| LDHA | lactate dehydrogenase A | 0.0211633 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.146106 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.116908 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.113539 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0809113 |
| HMGA2 | high mobility group AT-hook 2 | -0.0794814 |
| ANGPTL4 | angiopoietin-like 4 | -0.0699887 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0688926 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0674039 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0673373 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0591017 |
| SDC4 | syndecan 4 | -0.0585597 |
| PRSS23 | protease, serine, 23 | -0.0541044 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0522031 |
| VIM | vimentin | -0.0508298 |
| SLC38A2 | solute carrier family 38, member 2 | -0.049012 |
| IGF2 | insulin-like growth factor 2 | -0.0486749 |
| RIGI | RNA sensor RIG-I | -0.0480576 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0467692 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0456452 |
| CD44 | CD44 molecule (Indian blood group) | -0.0453791 |
| IER3 | immediate early response 3 | -0.0450133 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0447421 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0443223 |
| S100A10 | S100 calcium binding protein A10 | -0.0441142 |
| PRR16 | proline rich 16 | -0.0421737 |
| SVIL | supervillin | -0.0419117 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0416549 |
| RPL35A | ribosomal protein L35a | -0.0405843 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0400567 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0395904 |
| PTMA | prothymosin, alpha | -0.0393543 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.0391628 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0391144 |
| PCED1B | PC-esterase domain containing 1B | -0.0387209 |
| NPAS2 | neuronal PAS domain protein 2 | -0.038655 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0371971 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0361867 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0360433 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.035948 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0354124 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0352387 |
| HLA-C | major histocompatibility complex, class I, C | -0.0348263 |
| HLA-B | major histocompatibility complex, class I, B | -0.033925 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0332331 |
| POTEF | POTE ankyrin domain family, member F | -0.0330262 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0328995 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.032753 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0325714 |
| PODXL | podocalyxin-like | -0.0322439 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0317433 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0313118 |
| NALCN | sodium leak channel, non selective | -0.0312225 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0309158 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0305412 |
| FLNB | filamin B, beta | -0.0302705 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0301243 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0298271 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | -0.0295543 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0281355 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.028129 |
| COL5A1 | collagen, type V, alpha 1 | -0.0279836 |
| GPC6 | glypican 6 | -0.027952 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0279293 |
| KLF3 | Kruppel-like factor 3 (basic) | -0.027572 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0273566 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0272654 |
| ZFHX3 | zinc finger homeobox 3 | -0.0271115 |
| MYO9B | myosin IXB | -0.027037 |
| MT2A | metallothionein 2A | -0.0265566 |
| HLA-A | major histocompatibility complex, class I, A | -0.0264784 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | -0.0263031 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0260226 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0259518 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0258141 |
| RAI14 | retinoic acid induced 14 | -0.0257638 |
| PRKCA | protein kinase C, alpha | -0.0251631 |
| ATG7 | autophagy related 7 | -0.024623 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0245102 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0242166 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0241512 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0239516 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0238315 |
| ACTG1 | actin gamma 1 | -0.0238074 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0235509 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.023407 |
| CCND1 | cyclin D1 | -0.0233335 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0231749 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0230865 |
| UBB | ubiquitin B | -0.0229941 |
| CCDC91 | coiled-coil domain containing 91 | -0.0224955 |
| PLEK2 | pleckstrin 2 | -0.0224264 |
| PURA | purine-rich element binding protein A | -0.0222551 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0222274 |
| PFN1 | profilin 1 | -0.0220885 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | -0.0219197 |
| ZBTB7A | zinc finger and BTB domain containing 7A | -0.0218463 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0215404 |
| TRIM56 | tripartite motif containing 56 | -0.0215078 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0214649 |
| SQSTM1 | sequestosome 1 | -0.0213572 |
