| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Apalutamide perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Apalutamide_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.129867 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.100609 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0764506 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0714058 |
| HMGA2 | high mobility group AT-hook 2 | 0.0674896 |
| AHR | aryl hydrocarbon receptor | 0.0637174 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0615626 |
| ITGA1 | integrin, alpha 1 | 0.0550002 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0528858 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0490424 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0452466 |
| CENPF | centromere protein F, 350/400kDa | 0.0428621 |
| GLIS3 | GLIS family zinc finger 3 | 0.0394045 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0388917 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0387041 |
| NRP1 | neuropilin 1 | 0.0376594 |
| DST | dystonin | 0.0374877 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.033538 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0329933 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0320976 |
| RUNX2 | runt-related transcription factor 2 | 0.0320236 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0319982 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.031767 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0315911 |
| OSMR | oncostatin M receptor | 0.0314406 |
| VEGFC | vascular endothelial growth factor C | 0.0309867 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0304302 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0301209 |
| PELO | pelota homolog (Drosophila) | 0.0299604 |
| EREG | epiregulin | 0.0290747 |
| PRELID2 | PRELI domain containing 2 | 0.0283348 |
| ETV6 | ets variant 6 | 0.0276852 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0270292 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0268942 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0253551 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0252362 |
| FAT1 | FAT atypical cadherin 1 | 0.0250382 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0250033 |
| MKI67 | marker of proliferation Ki-67 | 0.0246844 |
| RTN4 | reticulon 4 | 0.0234071 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0233358 |
| TPM3 | tropomyosin 3 | 0.0232358 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.023128 |
| MAP1B | microtubule-associated protein 1B | 0.0229954 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0229547 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0229132 |
| SYT1 | synaptotagmin I | 0.022542 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0225346 |
| VEGFA | vascular endothelial growth factor A | 0.0217754 |
| SLTM | SAFB-like, transcription modulator | 0.0215304 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0213148 |
| CLTC | clathrin, heavy chain (Hc) | 0.0212484 |
| GPC6 | glypican 6 | 0.021156 |
| TXNIP | thioredoxin interacting protein | 0.0209668 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0206898 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0205673 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0205624 |
| PCBP2 | poly(rC) binding protein 2 | 0.0205263 |
| FRYL | FRY-like | 0.0204078 |
| SMOX | spermine oxidase | 0.020117 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0199707 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0198355 |
| EFNA5 | ephrin-A5 | 0.0196432 |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase | 0.0196206 |
| SMYD3 | SET and MYND domain containing 3 | 0.0196047 |
| OXR1 | oxidation resistance 1 | 0.0195937 |
| TXNRD1 | thioredoxin reductase 1 | 0.0194506 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0193671 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.0193096 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0189195 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0185637 |
| TPR | translocated promoter region, nuclear basket protein | 0.0184948 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0184155 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0181343 |
| UBXN4 | UBX domain protein 4 | 0.0179982 |
| RBM39 | RNA binding motif protein 39 | 0.017958 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.0177444 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0175584 |
| SYNJ2 | synaptojanin 2 | 0.0175526 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0173485 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0173321 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0173005 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0172957 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0171387 |
| MAP3K9 | mitogen-activated protein kinase kinase kinase 9 | 0.017025 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | 0.0168294 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.016702 |
| RASAL2 | RAS protein activator like 2 | 0.0166683 |
| FAM13A | family with sequence similarity 13, member A | 0.0166378 |
| GOLPH3 | golgi phosphoprotein 3 (coat-protein) | 0.0165447 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0163842 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0163837 |
| ETNK1 | ethanolamine kinase 1 | 0.0163578 |
| NOTCH2 | notch 2 | 0.0162218 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0161623 |
| IL6ST | interleukin 6 signal transducer | 0.0157768 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0157522 |
| PCM1 | pericentriolar material 1 | 0.0157106 |
| SON | SON DNA binding protein | 0.015693 |
| CDC73 | cell division cycle 73 | 0.0156682 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.205742 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.182037 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.12631 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.1219 |
| HLA-B | major histocompatibility complex, class I, B | -0.116886 |
| FTL | ferritin, light polypeptide | -0.113323 |
| TMSB10 | thymosin beta 10 | -0.110877 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0990001 |
| RPL35A | ribosomal protein L35a | -0.0739075 |
| ACTG1 | actin gamma 1 | -0.0727171 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0633978 |
| IER3 | immediate early response 3 | -0.0628512 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0615376 |
| RPL31 | ribosomal protein L31 | -0.0613463 |
| RPLP1 | ribosomal protein, large, P1 | -0.0586516 |
| RPS24 | ribosomal protein S24 | -0.05769 |
| SQSTM1 | sequestosome 1 | -0.052293 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0496477 |
| RPL37A | ribosomal protein L37a | -0.0477306 |
| RPS6 | ribosomal protein S6 | -0.0463264 |
| TMSB4X | thymosin beta 4, X-linked | -0.0463098 |
| RPS25 | ribosomal protein S25 | -0.0459835 |
| S100A6 | S100 calcium binding protein A6 | -0.0452457 |
| INTS6 | integrator complex subunit 6 | -0.0433799 |
| NDRG1 | N-myc downstream regulated 1 | -0.0431458 |
| VIM | vimentin | -0.0425695 |
| S100A10 | S100 calcium binding protein A10 | -0.0423194 |
| RPS8 | ribosomal protein S8 | -0.0421432 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0411191 |
| RPL38 | ribosomal protein L38 | -0.0400963 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0397237 |
| RPL34 | ribosomal protein L34 | -0.0391325 |
| RPL37 | ribosomal protein L37 | -0.038998 |
| RPS29 | ribosomal protein S29 | -0.0381524 |
| RPL9 | ribosomal protein L9 | -0.0376919 |
| RPS11 | ribosomal protein S11 | -0.0374477 |
| RPS27A | ribosomal protein S27a | -0.0362771 |
| RPS21 | ribosomal protein S21 | -0.0354267 |
| RPS23 | ribosomal protein S23 | -0.0342753 |
| RPL19 | ribosomal protein L19 | -0.0327683 |
| RPS19 | ribosomal protein S19 | -0.0323899 |
| RPL23 | ribosomal protein L23 | -0.031755 |
| MT2A | metallothionein 2A | -0.0314292 |
| EGR1 | early growth response 1 | -0.0312369 |
| RPL26 | ribosomal protein L26 | -0.031036 |
| S100A9 | S100 calcium binding protein A9 | -0.0302661 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0292778 |
| GNAS | GNAS complex locus | -0.0288607 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0288311 |
| RPLP2 | ribosomal protein, large, P2 | -0.0286194 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0281991 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0281465 |
| RPS16 | ribosomal protein S16 | -0.0276351 |
| CD63 | CD63 molecule | -0.0275818 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0274385 |
| MTDH | metadherin | -0.0273689 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0273435 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.026776 |
| HLA-A | major histocompatibility complex, class I, A | -0.0266871 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0265148 |
| RPS13 | ribosomal protein S13 | -0.0264951 |
| RPL36A | ribosomal protein L36a | -0.0262266 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | -0.0262164 |
| LRRC23 | leucine rich repeat containing 23 | -0.0261129 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0257898 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0255997 |
| UBC | ubiquitin C | -0.0252682 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0251422 |
| RPS27 | ribosomal protein S27 | -0.0250655 |
| RPS3 | ribosomal protein S3 | -0.0250116 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0249644 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0243939 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.02411 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0240833 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0240239 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.023712 |
| RPL28 | ribosomal protein L28 | -0.0236298 |
| TBCA | tubulin folding cofactor A | -0.0236218 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0234436 |
| PGK1 | phosphoglycerate kinase 1 | -0.0233154 |
| RPS20 | ribosomal protein S20 | -0.0229488 |
| CUX1 | cut-like homeobox 1 | -0.0228064 |
| RPL11 | ribosomal protein L11 | -0.0227367 |
| PKM | pyruvate kinase, muscle | -0.0223581 |
| SRP14 | signal recognition particle 14kDa (homologous Alu RNA binding protein) | -0.0223254 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0222761 |
| RPL12 | ribosomal protein L12 | -0.022229 |
| RPS14 | ribosomal protein S14 | -0.0218802 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0218314 |
| FBXO11 | F-box protein 11 | -0.0215978 |
| RPLP0 | ribosomal protein, large, P0 | -0.0214184 |
| B2M | beta-2-microglobulin | -0.0210774 |
| MCL1 | myeloid cell leukemia 1 | -0.0206583 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0205446 |
| RPS5 | ribosomal protein S5 | -0.0204635 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0204365 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0204075 |
| AHNAK | AHNAK nucleoprotein | -0.0202091 |
| RPL8 | ribosomal protein L8 | -0.0201357 |
| RPS12 | ribosomal protein S12 | -0.0199826 |
