| Dataset | CTD Gene-Chemical Interactions |
| Category | physical interactions |
| Type | chemical |
| Description | A tetracyclic diterpenoid that has an tetradecahydro-8,11a-methanocyclohepta[a]naphthalene skeleton with two hydroxymethyl substituents at positions 4 and 9, two methyl substituents at positions 4 and 11b and two hydroxy substituents at positions 3 and 9. An antibiotic with antiviral and antimitotical properties. Aphidicolin is a reversible inhibitor of eukaryotic nuclear DNA replication. (Chemical Entities of Biological Interest Ontology, CHEBI_2766) |
| External Link | http://ctdbase.org/detail.go?type=chem&acc=D016590 |
| Similar Terms | |
| Downloads & Tools |
10 genes/proteins interacting with the chemical Aphidicolin from the curated CTD Gene-Chemical Interactions dataset.
| Symbol | Name |
|---|---|
| ATM | ATM serine/threonine kinase |
| ATR | ATR serine/threonine kinase |
| BSCL2 | Berardinelli-Seip congenital lipodystrophy 2 (seipin) |
| CHEK1 | checkpoint kinase 1 |
| CHEK2 | checkpoint kinase 2 |
| H2AFX | H2A histone family, member X |
| POLA1 | polymerase (DNA directed), alpha 1, catalytic subunit |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide |
| TNFRSF8 | tumor necrosis factor receptor superfamily, member 8 |
| TRIM28 | tripartite motif containing 28 |
