Apigenin Gene Set

Dataset CTD Gene-Chemical Interactions
Category physical interactions
Type chemical
Description A trihydroxyflavone that is flavone substituted by hydroxy groups at positions 4', 5 and 7. (Chemical Entities of Biological Interest Ontology, CHEBI_18388)
External Link http://ctdbase.org/detail.go?type=chem&acc=D047310
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Genes

100 genes/proteins interacting with the chemical Apigenin from the curated CTD Gene-Chemical Interactions dataset.

Symbol Name
A2M alpha-2-macroglobulin
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
AFP alpha-fetoprotein
AHR aryl hydrocarbon receptor
AIP aryl hydrocarbon receptor interacting protein
AKT1 v-akt murine thymoma viral oncogene homolog 1
APAF1 apoptotic peptidase activating factor 1
ARNT aryl hydrocarbon receptor nuclear translocator
ATF6 activating transcription factor 6
B3GALT5 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5
BAX BCL2-associated X protein
BCL2 B-cell CLL/lymphoma 2
BCL2L1 BCL2-like 1
BID BH3 interacting domain death agonist
BIRC3 baculoviral IAP repeat containing 3
CASP12 caspase 12 (gene/pseudogene)
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP7 caspase 7, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CAT catalase
CCNB1 cyclin B1
CD40 CD40 molecule, TNF receptor superfamily member 5
CDK1 cyclin-dependent kinase 1
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CKM creatine kinase, muscle
CYCS cytochrome c, somatic
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
DDIT3 DNA-damage-inducible transcript 3
ERBB2 erb-b2 receptor tyrosine kinase 2
ERN1 endoplasmic reticulum to nucleus signaling 1
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
FOS FBJ murine osteosarcoma viral oncogene homolog
GCLC glutamate-cysteine ligase, catalytic subunit
GCLM glutamate-cysteine ligase, modifier subunit
GLI1 GLI family zinc finger 1
GYPA glycophorin A (MNS blood group)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HMOX1 heme oxygenase 1
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPA8 heat shock 70kDa protein 8
ICAM1 intercellular adhesion molecule 1
IFNG interferon, gamma
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IL1B interleukin 1, beta
IL4 interleukin 4
IL6 interleukin 6
JUN jun proto-oncogene
LEP leptin
LTF lactotransferrin
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MAPK9 mitogen-activated protein kinase 9
MMP1 matrix metallopeptidase 1
MMP9 matrix metallopeptidase 9
NFE2L2 nuclear factor, erythroid 2-like 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NOS2 nitric oxide synthase 2, inducible
NR1I2 nuclear receptor subfamily 1, group I, member 2
PARP1 poly (ADP-ribose) polymerase 1
PGR progesterone receptor
PKM pyruvate kinase, muscle
POU5F1 POU class 5 homeobox 1
PPARG peroxisome proliferator-activated receptor gamma
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
S1PR1 sphingosine-1-phosphate receptor 1
S1PR2 sphingosine-1-phosphate receptor 2
S1PR3 sphingosine-1-phosphate receptor 3
SELE selectin E
SHBG sex hormone-binding globulin
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SOD1 superoxide dismutase 1, soluble
SPHK1 sphingosine kinase 1
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
TNF tumor necrosis factor
TP53 tumor protein p53
TP53I3 tumor protein p53 inducible protein 3
TP63 tumor protein p63
TP73 tumor protein p73
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1
UGT1A10 UDP glucuronosyltransferase 1 family, polypeptide A10
UGT1A7 UDP glucuronosyltransferase 1 family, polypeptide A7
UGT1A8 UDP glucuronosyltransferase 1 family, polypeptide A8
UGT1A9 UDP glucuronosyltransferase 1 family, polypeptide A9
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15
VCAM1 vascular cell adhesion molecule 1