Apraxia Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description An agnosia that is a loss of the ability to map out physical actions in order to repeat them in functional activities. (Human Disease Ontology, DOID_0060135)
External Link https://www.disgenet.org/browser/0/1/0/C0543874
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Genes

111 genes associated with the disease Apraxia in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ACE angiotensin I converting enzyme
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ALDH3A2 aldehyde dehydrogenase 3 family, member A2
APLN apelin
APOB apolipoprotein B
APOE apolipoprotein E
APTX aprataxin
ARX aristaless related homeobox
B3GAT1 beta-1,3-glucuronyltransferase 1
BBS1 Bardet-Biedl syndrome 1
BCAR1 breast cancer anti-estrogen resistance 1
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
BRSK2 BR serine/threonine kinase 2
CASP1 caspase 1, apoptosis-related cysteine peptidase
CAV1 caveolin 1, caveolae protein, 22kDa
CCHCR1 coiled-coil alpha-helical rod protein 1
CCL2 chemokine (C-C motif) ligand 2
CCR2 chemokine (C-C motif) receptor 2
CD28 CD28 molecule
CD34 CD34 molecule
CHD1 chromodomain helicase DNA binding protein 1
CHD3 chromodomain helicase DNA binding protein 3
CHD4 chromodomain helicase DNA binding protein 4
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal)
CNTNAP2 contactin associated protein-like 2
COG4 component of oligomeric golgi complex 4
CRP C-reactive protein, pentraxin-related
CSE1L CSE1 chromosome segregation 1-like (yeast)
CST3 cystatin C
CSTB cystatin B (stefin B)
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTNND1 catenin (cadherin-associated protein), delta 1
CTSC cathepsin C
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR2 chemokine (C-X-C motif) receptor 2
CYLD cylindromatosis (turban tumor syndrome)
EDN1 endothelin 1
ERC1 ELKS/RAB6-interacting/CAST family member 1
FASN fatty acid synthase
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
FOXP1 forkhead box P1
FOXP2 forkhead box P2
GAL galanin/GMAP prepropeptide
GALT galactose-1-phosphate uridylyltransferase
GATAD2B GATA zinc finger domain containing 2B
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A
IL18 interleukin 18
IL1B interleukin 1, beta
IL1R2 interleukin 1 receptor, type II
IL6 interleukin 6
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa
KDM6B lysine (K)-specific demethylase 6B
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLK1 kallikrein 1
LCN2 lipocalin 2
LGALS1 lectin, galactoside-binding, soluble, 1
LPA lipoprotein, Lp(a)
LRP1 low density lipoprotein receptor-related protein 1
MAPT microtubule-associated protein tau
MECP2 methyl CpG binding protein 2
MMP12 matrix metallopeptidase 12
MMP2 matrix metallopeptidase 2
MMP3 matrix metallopeptidase 3
MMP9 matrix metallopeptidase 9
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MYL2 myosin, light chain 2, regulatory, cardiac, slow
MYL9 myosin, light chain 9, regulatory
MYLK myosin light chain kinase
NDP Norrie disease (pseudoglioma)
NLRP3 NLR family, pyrin domain containing 3
NONO non-POU domain containing, octamer-binding
NOS3 nitric oxide synthase 3 (endothelial cell)
NPC1 Niemann-Pick disease, type C1
NPHP1 nephronophthisis 1 (juvenile)
NUCB2 nucleobindin 2
PACS1 phosphofurin acidic cluster sorting protein 1
PECAM1 platelet/endothelial cell adhesion molecule 1
PHLDA2 pleckstrin homology-like domain, family A, member 2
PLXNA2 plexin A2
PON1 paraoxonase 1
POT1 protection of telomeres 1
PRKCI protein kinase C, iota
PSD pleckstrin and Sec7 domain containing
PTEN phosphatase and tensin homolog
PTPRJ protein tyrosine phosphatase, receptor type, J
RAI1 retinoic acid induced 1
RNF135 ring finger protein 135
RO60 Ro60, Y RNA binding protein
SELENBP1 selenium binding protein 1
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SHBG sex hormone-binding globulin
SLC25A15 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SPART spartin
SQSTM1 sequestosome 1
SRPX2 sushi-repeat containing protein, X-linked 2
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3
TIMP4 TIMP metallopeptidase inhibitor 4
TNF tumor necrosis factor
TP53 tumor protein p53
TPO thyroid peroxidase
TRAPPC11 trafficking protein particle complex 11
TXN thioredoxin
VCP valosin containing protein
XDH xanthine dehydrogenase
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
ZDHHC24 zinc finger, DHHC-type containing 24
ZGRF1 zinc finger, GRF-type containing 1