| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Aprepitant perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Aprepitant_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.122096 |
| FNIP1 | folliculin interacting protein 1 | 0.0791242 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0764604 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0722454 |
| USP54 | ubiquitin specific peptidase 54 | 0.0564525 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0536888 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0531789 |
| SMAD3 | SMAD family member 3 | 0.0531394 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.0466039 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0461446 |
| PGK1 | phosphoglycerate kinase 1 | 0.0460427 |
| MSI2 | musashi RNA-binding protein 2 | 0.0457137 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0455871 |
| TMPRSS4 | transmembrane protease, serine 4 | 0.0443851 |
| FOXO3 | forkhead box O3 | 0.0436296 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0433409 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0432854 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0424533 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0404671 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0401293 |
| KIF16B | kinesin family member 16B | 0.038259 |
| TJP2 | tight junction protein 2 | 0.0378915 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | 0.0354721 |
| STS | steroid sulfatase (microsomal), isozyme S | 0.034968 |
| NDRG1 | N-myc downstream regulated 1 | 0.0337878 |
| SCARB1 | scavenger receptor class B, member 1 | 0.033753 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0333553 |
| GRK3 | G protein-coupled receptor kinase 3 | 0.0333352 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0318814 |
| YME1L1 | YME1-like 1 ATPase | 0.0316722 |
| ERBIN | erbb2 interacting protein | 0.0316468 |
| PRKCA | protein kinase C, alpha | 0.0316001 |
| DNMBP | dynamin binding protein | 0.0314955 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.030988 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0307504 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0305136 |
| PTEN | phosphatase and tensin homolog | 0.0301237 |
| DSCAML1 | Down syndrome cell adhesion molecule like 1 | 0.0299975 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | 0.0299308 |
| GOLGA2 | golgin A2 | 0.0299283 |
| EREG | epiregulin | 0.0292519 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0287395 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0283923 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0280858 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0276944 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.027679 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.027469 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0274562 |
| UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked | 0.0270012 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0269695 |
| CANX | calnexin | 0.0268121 |
| ARRDC3 | arrestin domain containing 3 | 0.0266091 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0259394 |
| FDPS | farnesyl diphosphate synthase | 0.025865 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0258617 |
| MLPH | melanophilin | 0.0256476 |
| EPB41 | erythrocyte membrane protein band 4.1 | 0.0254038 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0250062 |
| LURAP1L | leucine rich adaptor protein 1-like | 0.0249173 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.0247122 |
| CMPK1 | cytidine monophosphate (UMP-CMP) kinase 1, cytosolic | 0.0246681 |
| H1-0 | H1.0 linker histone | 0.0242973 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0240769 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0237925 |
| RNF149 | ring finger protein 149 | 0.0236381 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0236028 |
| RLIM | ring finger protein, LIM domain interacting | 0.0235145 |
| OSBPL9 | oxysterol binding protein-like 9 | 0.0234581 |
| TXNIP | thioredoxin interacting protein | 0.0233887 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0231416 |
| AREG | amphiregulin | 0.0231339 |
| ZC3H13 | zinc finger CCCH-type containing 13 | 0.0231292 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0230362 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0229759 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0225886 |
| WDR26 | WD repeat domain 26 | 0.0223963 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | 0.0223839 |
| NMU | neuromedin U | 0.0220155 |
| ZNF160 | zinc finger protein 160 | 0.0219022 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0218758 |
| FLNB | filamin B, beta | 0.0217406 |
| PADI1 | peptidyl arginine deiminase, type I | 0.0217217 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0216467 |
| CKLF | chemokine-like factor | 0.0216429 |
| VEGFA | vascular endothelial growth factor A | 0.021481 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0211793 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | 0.0209031 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | 0.0208113 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0207697 |
| EMC2 | ER membrane protein complex subunit 2 | 0.0207131 |
| RREB1 | ras responsive element binding protein 1 | 0.0206416 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0206396 |
| STYXL2 | serine/threonine/tyrosine interacting like 2 | 0.0205198 |
| DUSP10 | dual specificity phosphatase 10 | 0.0203959 |
| SDC4 | syndecan 4 | 0.0203901 |
| COPA | coatomer protein complex, subunit alpha | 0.0200876 |
| ACSS2 | acyl-CoA synthetase short-chain family member 2 | 0.0200166 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | 0.0198911 |
| GSDMB | gasdermin B | 0.0198589 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | 0.0194999 |
| Symbol | Name | Standardized Value |
|---|---|---|
| B2M | beta-2-microglobulin | -0.116956 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.104463 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0968374 |
| RUNX1 | runt-related transcription factor 1 | -0.0967673 |
| LMO7 | LIM domain 7 | -0.09642 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.087919 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0809884 |
| PTMA | prothymosin, alpha | -0.0777939 |
| IRF1 | interferon regulatory factor 1 | -0.07633 |
| RPS6 | ribosomal protein S6 | -0.0730578 |
| LCN2 | lipocalin 2 | -0.0718271 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0667481 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0615136 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0592519 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0568128 |
| MX1 | MX dynamin-like GTPase 1 | -0.0545778 |
| EZR | ezrin | -0.0528879 |
| RRBP1 | ribosome binding protein 1 | -0.0503055 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.050242 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0499895 |
| TRERF1 | transcriptional regulating factor 1 | -0.0489422 |
| SP100 | SP100 nuclear antigen | -0.0466167 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0458511 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0445295 |
| ACTG1 | actin gamma 1 | -0.0438907 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.042796 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0418287 |
| MPHOSPH8 | M-phase phosphoprotein 8 | -0.0409296 |
| RIGI | RNA sensor RIG-I | -0.0407733 |
| MAP7 | microtubule-associated protein 7 | -0.040416 |
| ABHD2 | abhydrolase domain containing 2 | -0.0401118 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0398129 |
| PKM | pyruvate kinase, muscle | -0.0397028 |
| DSTN | destrin (actin depolymerizing factor) | -0.0384841 |
| MX2 | MX dynamin-like GTPase 2 | -0.0381259 |
| RBM39 | RNA binding motif protein 39 | -0.0380303 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.0380233 |
| BCLAF1 | BCL2-associated transcription factor 1 | -0.0378771 |
| ANXA2 | annexin A2 | -0.0378464 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0376769 |
| HLA-B | major histocompatibility complex, class I, B | -0.0358663 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0355377 |
| RPL35A | ribosomal protein L35a | -0.0343597 |
| EPHB2 | EPH receptor B2 | -0.0342343 |
| RPLP1 | ribosomal protein, large, P1 | -0.0341649 |
| RPL23 | ribosomal protein L23 | -0.033727 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0337176 |
| PLSCR1 | phospholipid scramblase 1 | -0.0334239 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0327563 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0325746 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0321043 |
| EFNB2 | ephrin-B2 | -0.0312507 |
| BPTF | bromodomain PHD finger transcription factor | -0.0311087 |
| CCNL1 | cyclin L1 | -0.0306936 |
| MEIS2 | Meis homeobox 2 | -0.0305611 |
| RPS8 | ribosomal protein S8 | -0.0304103 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.030224 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | -0.0298566 |
| RPL37A | ribosomal protein L37a | -0.0298238 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0295153 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.028709 |
| RPS29 | ribosomal protein S29 | -0.0286297 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0285407 |
| PERP | PERP, TP53 apoptosis effector | -0.0281387 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0281243 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0280386 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0279147 |
| MCL1 | myeloid cell leukemia 1 | -0.0275877 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | -0.0274776 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0273284 |
| S100A6 | S100 calcium binding protein A6 | -0.0271407 |
| MORF4L2 | mortality factor 4 like 2 | -0.0271385 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0269201 |
| POTEF | POTE ankyrin domain family, member F | -0.0267353 |
| EGR1 | early growth response 1 | -0.0263428 |
| ANXA1 | annexin A1 | -0.0262405 |
| RPL26 | ribosomal protein L26 | -0.0261491 |
| XAF1 | XIAP associated factor 1 | -0.026118 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0261 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0259344 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0256092 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0255383 |
| LAP3 | leucine aminopeptidase 3 | -0.0254973 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0254951 |
| RPL12 | ribosomal protein L12 | -0.0254518 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.0254503 |
| FUS | FUS RNA binding protein | -0.0254052 |
| CENPF | centromere protein F, 350/400kDa | -0.0253465 |
| RPS17 | ribosomal protein S17 | -0.025019 |
| RASGEF1B | RasGEF domain family, member 1B | -0.024958 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | -0.0249491 |
| WWOX | WW domain containing oxidoreductase | -0.0248327 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0246904 |
| RBM25 | RNA binding motif protein 25 | -0.0243793 |
| PER2 | period circadian clock 2 | -0.0243631 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0243334 |
| MUC13 | mucin 13, cell surface associated | -0.0243153 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | -0.0243048 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0242458 |
| LMNA | lamin A/C | -0.0241672 |
