| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Aprepitant perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Aprepitant_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.148043 |
| GOLGA4 | golgin A4 | 0.0774148 |
| ANK2 | ankyrin 2, neuronal | 0.0513989 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.049852 |
| TMEM41B | transmembrane protein 41B | 0.0460745 |
| PDGFC | platelet derived growth factor C | 0.0443694 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0438738 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0438085 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0419706 |
| RTN4 | reticulon 4 | 0.0418217 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0408114 |
| FLNB | filamin B, beta | 0.0407654 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0399122 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0393137 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0383816 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0353332 |
| ZNF292 | zinc finger protein 292 | 0.0353307 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0344059 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.034074 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0337991 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0324751 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0320547 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0318861 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0316377 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0305574 |
| SBF2 | SET binding factor 2 | 0.0302107 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0301236 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0300346 |
| CD47 | CD47 molecule | 0.02989 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0294282 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0292297 |
| COG5 | component of oligomeric golgi complex 5 | 0.0289277 |
| VCL | vinculin | 0.0286206 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0285969 |
| RUSC2 | RUN and SH3 domain containing 2 | 0.0281683 |
| TXNRD1 | thioredoxin reductase 1 | 0.027924 |
| JMJD1C | jumonji domain containing 1C | 0.0270436 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0269967 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0269233 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0267154 |
| PALS1 | protein associated with LIN7 1, MAGUK p55 family member | 0.0261291 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0254682 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0254473 |
| ZNF608 | zinc finger protein 608 | 0.025194 |
| NUP58 | nucleoporin 58 | 0.025085 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0245385 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.024468 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | 0.0244083 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0234485 |
| FNIP1 | folliculin interacting protein 1 | 0.0234236 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0232074 |
| ENO1 | enolase 1, (alpha) | 0.023155 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0228936 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0228312 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 | 0.0227598 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0225282 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | 0.0225154 |
| TMEM65 | transmembrane protein 65 | 0.0224855 |
| DIAPH2 | diaphanous-related formin 2 | 0.0224485 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0223972 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0223706 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0223232 |
| LSM14A | LSM14A, SCD6 homolog A (S. cerevisiae) | 0.0219579 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0218024 |
| SMNDC1 | survival motor neuron domain containing 1 | 0.0217843 |
| SLC35A3 | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 | 0.0214974 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0213275 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0212377 |
| TMSB4X | thymosin beta 4, X-linked | 0.0210662 |
| NBAS | neuroblastoma amplified sequence | 0.0209145 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0209032 |
| CAMSAP2 | calmodulin regulated spectrin-associated protein family, member 2 | 0.0208199 |
| COPA | coatomer protein complex, subunit alpha | 0.0206907 |
| CEP192 | centrosomal protein 192kDa | 0.0206189 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | 0.0205227 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0203831 |
| PGM3 | phosphoglucomutase 3 | 0.0203516 |
| MT2A | metallothionein 2A | 0.0201544 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0200375 |
| SFPQ | splicing factor proline/glutamine-rich | 0.019975 |
| RHBDD1 | rhomboid domain containing 1 | 0.0196918 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 0.0195404 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0195118 |
| EPB41 | erythrocyte membrane protein band 4.1 | 0.0193007 |
| CNOT6L | CCR4-NOT transcription complex, subunit 6-like | 0.0192386 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0191547 |
| SQSTM1 | sequestosome 1 | 0.019063 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0189027 |
| RBMS2 | RNA binding motif, single stranded interacting protein 2 | 0.0187868 |
| PLK2 | polo-like kinase 2 | 0.0187433 |
| KIF5C | kinesin family member 5C | 0.0186945 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0185942 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0185107 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.018435 |
| RARS1 | arginyl-tRNA synthetase 1 | 0.0183338 |
| METTL15 | methyltransferase like 15 | 0.0183046 |
| COG6 | component of oligomeric golgi complex 6 | 0.0182384 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0182304 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0181888 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0180095 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PKM | pyruvate kinase, muscle | -0.0810861 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0663095 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0590098 |
| BMP10 | bone morphogenetic protein 10 | -0.05877 |
| FOXP1 | forkhead box P1 | -0.0552441 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0515536 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0459893 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0435917 |
| GLI3 | GLI family zinc finger 3 | -0.0411875 |
| HDAC9 | histone deacetylase 9 | -0.0376412 |
| RPS6 | ribosomal protein S6 | -0.0364668 |
| RPS8 | ribosomal protein S8 | -0.0344936 |
| ACTG1 | actin gamma 1 | -0.0324305 |
| PTMA | prothymosin, alpha | -0.0317582 |
| RPS5 | ribosomal protein S5 | -0.0311977 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | -0.0308589 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0307264 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0289108 |
| CCND1 | cyclin D1 | -0.0288213 |
| RPLP1 | ribosomal protein, large, P1 | -0.0280645 |
| MYO5C | myosin VC | -0.0278978 |
| NAV2 | neuron navigator 2 | -0.0276387 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0270127 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.026525 |
| DIAPH3 | diaphanous-related formin 3 | -0.0257321 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.024964 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | -0.024337 |
| RPS24 | ribosomal protein S24 | -0.0238687 |
| CUX1 | cut-like homeobox 1 | -0.023776 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0233708 |
| RPL37A | ribosomal protein L37a | -0.0231965 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0229643 |
| ZNF438 | zinc finger protein 438 | -0.0228643 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0227961 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0227447 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0227039 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0225897 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.022236 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0221397 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.0219922 |
| SP100 | SP100 nuclear antigen | -0.0219641 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0218493 |
| RPL35A | ribosomal protein L35a | -0.0217906 |
| RPL7A | ribosomal protein L7a | -0.0214175 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0213599 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0212043 |
| ZNF207 | zinc finger protein 207 | -0.0211708 |
| AHNAK | AHNAK nucleoprotein | -0.0208554 |
| RPL19 | ribosomal protein L19 | -0.0204965 |
| RPL4 | ribosomal protein L4 | -0.0198215 |
| BZW2 | basic leucine zipper and W2 domains 2 | -0.0197366 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0193731 |
| EBNA1BP2 | EBNA1 binding protein 2 | -0.0193085 |
| RPS16 | ribosomal protein S16 | -0.019274 |
| KIF5B | kinesin family member 5B | -0.0192172 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0189694 |
| RPS23 | ribosomal protein S23 | -0.0189405 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0188088 |
| MACROD2 | MACRO domain containing 2 | -0.0187472 |
| RPS20 | ribosomal protein S20 | -0.0185954 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0185027 |
| GALNT5 | polypeptide N-acetylgalactosaminyltransferase 5 | -0.0183774 |
| RPS19 | ribosomal protein S19 | -0.0183679 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0181707 |
| RPS10 | ribosomal protein S10 | -0.0180305 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0179293 |
| GNAS | GNAS complex locus | -0.0179019 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0177187 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0173427 |
| RACK1 | receptor for activated C kinase 1 | -0.0172557 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0172229 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b | -0.0171431 |
| VIM | vimentin | -0.0171392 |
| PKP4 | plakophilin 4 | -0.0170539 |
| RPL30 | ribosomal protein L30 | -0.0169944 |
| S100A4 | S100 calcium binding protein A4 | -0.0168161 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0164951 |
| FN1 | fibronectin 1 | -0.0164733 |
| SLC25A6 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 | -0.0162426 |
| RIGI | RNA sensor RIG-I | -0.016242 |
| BPTF | bromodomain PHD finger transcription factor | -0.0161391 |
| EHBP1 | EH domain binding protein 1 | -0.015819 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0158162 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0158088 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0157946 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0157775 |
| LARS1 | leucyl-tRNA synthetase 1 | -0.0157444 |
| PDE7B | phosphodiesterase 7B | -0.015713 |
| WWOX | WW domain containing oxidoreductase | -0.0156936 |
| NUP153 | nucleoporin 153kDa | -0.0155858 |
| CRPPA | CDP-L-ribitol pyrophosphorylase A | -0.015578 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0152884 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | -0.0152348 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0152333 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.0152255 |
| RTN3 | reticulon 3 | -0.015224 |
| RPL23 | ribosomal protein L23 | -0.0150956 |
| BCOR | BCL6 corepressor | -0.0150552 |
| PPM1L | protein phosphatase, Mg2+/Mn2+ dependent, 1L | -0.0147178 |
| EXOC4 | exocyst complex component 4 | -0.0146619 |
