| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Aprepitant perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Aprepitant_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SOD2 | superoxide dismutase 2, mitochondrial | 0.198885 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.12395 |
| ADM | adrenomedullin | 0.112809 |
| PDE10A | phosphodiesterase 10A | 0.105876 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0940232 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0890891 |
| CADM1 | cell adhesion molecule 1 | 0.0880819 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0798196 |
| FMNL2 | formin-like 2 | 0.0714357 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0710777 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0684025 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.065381 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0647961 |
| DST | dystonin | 0.0647427 |
| OGA | O-GlcNAcase | 0.0642031 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0634792 |
| SPAG9 | sperm associated antigen 9 | 0.0623433 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0615517 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0610303 |
| ARRDC3 | arrestin domain containing 3 | 0.0605647 |
| GOLGA4 | golgin A4 | 0.0596526 |
| HELZ | helicase with zinc finger | 0.0587279 |
| ZNF292 | zinc finger protein 292 | 0.0576119 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0564092 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0519464 |
| ATP13A3 | ATPase type 13A3 | 0.0504596 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.048132 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.047315 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0450204 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0441684 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0435957 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.043592 |
| PCBP2 | poly(rC) binding protein 2 | 0.0427493 |
| MYOF | myoferlin | 0.0426356 |
| FNDC3B | fibronectin type III domain containing 3B | 0.042291 |
| FNIP1 | folliculin interacting protein 1 | 0.0417904 |
| CANX | calnexin | 0.0413085 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0409855 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0406602 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0404057 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.04004 |
| FLNB | filamin B, beta | 0.0383715 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | 0.0378553 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0361943 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0361304 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0359132 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0358914 |
| WTAP | Wilms tumor 1 associated protein | 0.0358347 |
| VEGFA | vascular endothelial growth factor A | 0.0357536 |
| INTS6 | integrator complex subunit 6 | 0.0357477 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0355255 |
| SQSTM1 | sequestosome 1 | 0.035136 |
| CNNM2 | cyclin and CBS domain divalent metal cation transport mediator 2 | 0.0350466 |
| FRMD4A | FERM domain containing 4A | 0.0349378 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0349221 |
| HDAC9 | histone deacetylase 9 | 0.0348727 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0348449 |
| CDK19 | cyclin-dependent kinase 19 | 0.0345915 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.034537 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0345366 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0344461 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0340296 |
| CCBE1 | collagen and calcium binding EGF domains 1 | 0.0339892 |
| NAV2 | neuron navigator 2 | 0.0333488 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0327876 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0326802 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0323745 |
| CEP250 | centrosomal protein 250kDa | 0.0323024 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0320903 |
| CD109 | CD109 molecule | 0.0319095 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0317324 |
| FRMPD4 | FERM and PDZ domain containing 4 | 0.0317222 |
| OPTN | optineurin | 0.0312049 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0308315 |
| STAG2 | stromal antigen 2 | 0.0298721 |
| SEPTIN9 | septin 9 | 0.0289564 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0289189 |
| SERINC1 | serine incorporator 1 | 0.0287693 |
| QKI | QKI, KH domain containing, RNA binding | 0.0281513 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0281419 |
| NT5C2 | 5'-nucleotidase, cytosolic II | 0.0278528 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0277284 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0276299 |
| NDRG1 | N-myc downstream regulated 1 | 0.027496 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0274889 |
| YTHDC1 | YTH domain containing 1 | 0.0274631 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0272621 |
| RYBP | RING1 and YY1 binding protein | 0.0271623 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0269918 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0265432 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0263155 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0260685 |
| AFF3 | AF4/FMR2 family, member 3 | 0.026046 |
| COL5A1 | collagen, type V, alpha 1 | 0.0260438 |
| RND3 | Rho family GTPase 3 | 0.0259777 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.025683 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0255936 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0254841 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0254627 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | 0.0254544 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.212492 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.165352 |
| CD44 | CD44 molecule (Indian blood group) | -0.150053 |
| TMSB10 | thymosin beta 10 | -0.140379 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.124511 |
| FN1 | fibronectin 1 | -0.104276 |
| HLA-B | major histocompatibility complex, class I, B | -0.0948989 |
| EGR1 | early growth response 1 | -0.0836238 |
| BICC1 | BicC family RNA binding protein 1 | -0.0821537 |
| FTL | ferritin, light polypeptide | -0.0720675 |
| RPS24 | ribosomal protein S24 | -0.0714797 |
| VCL | vinculin | -0.0669183 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0635923 |
| TPM4 | tropomyosin 4 | -0.0634935 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0603461 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0591032 |
| GLIS3 | GLIS family zinc finger 3 | -0.0582772 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0544907 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0540477 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0527469 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0499116 |
| IER3 | immediate early response 3 | -0.0488797 |
| OSMR | oncostatin M receptor | -0.047852 |
| CTSD | cathepsin D | -0.0430671 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0420798 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0411407 |
| PLIN2 | perilipin 2 | -0.0410959 |
| LDHA | lactate dehydrogenase A | -0.0407572 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0407457 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0398939 |
| CENPF | centromere protein F, 350/400kDa | -0.0378567 |
| RPLP1 | ribosomal protein, large, P1 | -0.0370606 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0370014 |
| TAPBP | TAP binding protein (tapasin) | -0.0365247 |
| MKI67 | marker of proliferation Ki-67 | -0.0361439 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0351555 |
| CDCP1 | CUB domain containing protein 1 | -0.0350244 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0347806 |
| TUBB | tubulin, beta class I | -0.0347047 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0344118 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0340652 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0337635 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0337323 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0337073 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0332606 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0326224 |
| MAP1B | microtubule-associated protein 1B | -0.0325103 |
| PKM | pyruvate kinase, muscle | -0.0324889 |
| GNAS | GNAS complex locus | -0.0315064 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.0314482 |
| RRBP1 | ribosome binding protein 1 | -0.0313882 |
| RIGI | RNA sensor RIG-I | -0.0307133 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0302132 |
| ACTG1 | actin gamma 1 | -0.0299974 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0293501 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0291481 |
| MX1 | MX dynamin-like GTPase 1 | -0.0286059 |
| TXNRD1 | thioredoxin reductase 1 | -0.0285508 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.027995 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0278388 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0277394 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0276833 |
| RPL23 | ribosomal protein L23 | -0.0276165 |
| RNF213 | ring finger protein 213 | -0.0275789 |
| RPS4X | ribosomal protein S4, X-linked | -0.0271612 |
| TNNC1 | troponin C type 1 (slow) | -0.0262439 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0261854 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.025967 |
| ENO1 | enolase 1, (alpha) | -0.0259088 |
| RPL36A | ribosomal protein L36a | -0.0257094 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0256896 |
| HLA-E | major histocompatibility complex, class I, E | -0.0255731 |
| DEK | DEK proto-oncogene | -0.0255034 |
| THBS1 | thrombospondin 1 | -0.02504 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0249834 |
| KLHL5 | kelch-like family member 5 | -0.0248965 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0245601 |
| SYAP1 | synapse associated protein 1 | -0.0243898 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0241777 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0240068 |
| PLSCR1 | phospholipid scramblase 1 | -0.0239895 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0237552 |
| FOXP1 | forkhead box P1 | -0.0237104 |
| RTN4 | reticulon 4 | -0.023323 |
| POTEF | POTE ankyrin domain family, member F | -0.0230594 |
| HMGA1 | high mobility group AT-hook 1 | -0.0228301 |
| NABP1 | nucleic acid binding protein 1 | -0.0228184 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0228 |
| REEP3 | receptor accessory protein 3 | -0.0227266 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0225994 |
| SYNJ2 | synaptojanin 2 | -0.0224863 |
| SAMHD1 | SAM domain and HD domain 1 | -0.0223303 |
| RPL4 | ribosomal protein L4 | -0.0220745 |
| NAV1 | neuron navigator 1 | -0.0219364 |
| CBX3 | chromobox homolog 3 | -0.0219307 |
| ARF1 | ADP-ribosylation factor 1 | -0.021885 |
| RPL35A | ribosomal protein L35a | -0.0217864 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0217505 |
| NRP1 | neuropilin 1 | -0.0215452 |
| TPM1 | tropomyosin 1 (alpha) | -0.0215219 |
