| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Aprepitant perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Aprepitant_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.186693 |
| FN1 | fibronectin 1 | 0.132597 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0537724 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0506899 |
| ARRDC3 | arrestin domain containing 3 | 0.0502924 |
| ADM | adrenomedullin | 0.0493714 |
| FMNL2 | formin-like 2 | 0.0480801 |
| PRSS23 | protease, serine, 23 | 0.0479861 |
| CDH13 | cadherin 13 | 0.0469842 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0461872 |
| ZNF292 | zinc finger protein 292 | 0.0460017 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0443721 |
| PTK2 | protein tyrosine kinase 2 | 0.0424408 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0417141 |
| PTGES2 | prostaglandin E synthase 2 | 0.0394184 |
| STC1 | stanniocalcin 1 | 0.0387112 |
| FRMD6 | FERM domain containing 6 | 0.0386472 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.038616 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0381048 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0378173 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0358495 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0354616 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | 0.0350939 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.035076 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0342743 |
| CD109 | CD109 molecule | 0.0336161 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0334555 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0331688 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0328121 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0326183 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0320598 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.031914 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0317973 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0316664 |
| RASA2 | RAS p21 protein activator 2 | 0.0310542 |
| COG5 | component of oligomeric golgi complex 5 | 0.0306508 |
| HDAC9 | histone deacetylase 9 | 0.0295396 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.028518 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0280442 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0278983 |
| LOX | lysyl oxidase | 0.0278209 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0269637 |
| MRTFA | myocardin related transcription factor A | 0.0269369 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0267454 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0266057 |
| COL5A2 | collagen, type V, alpha 2 | 0.0265586 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.0265387 |
| IGFBP7 | insulin-like growth factor binding protein 7 | 0.0263219 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0261732 |
| MYOF | myoferlin | 0.0260373 |
| TMSB4X | thymosin beta 4, X-linked | 0.0259849 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0251329 |
| RND3 | Rho family GTPase 3 | 0.0250986 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0250544 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0248606 |
| SDC4 | syndecan 4 | 0.0248219 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.024645 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0243017 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.0240591 |
| SETD5 | SET domain containing 5 | 0.02404 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0240138 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0237383 |
| ZNF207 | zinc finger protein 207 | 0.0234992 |
| ITGAV | integrin, alpha V | 0.023111 |
| RARS1 | arginyl-tRNA synthetase 1 | 0.023069 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0229893 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0229673 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0227718 |
| PLCB4 | phospholipase C, beta 4 | 0.0227624 |
| COL1A2 | collagen, type I, alpha 2 | 0.0226682 |
| HMGA2 | high mobility group AT-hook 2 | 0.0226566 |
| GPC6 | glypican 6 | 0.0226482 |
| MTMR3 | myotubularin related protein 3 | 0.0224801 |
| DDB1 | damage-specific DNA binding protein 1, 127kDa | 0.0223445 |
| PIAS1 | protein inhibitor of activated STAT, 1 | 0.0221644 |
| GOLGB1 | golgin B1 | 0.0221448 |
| G0S2 | G0/G1 switch 2 | 0.022042 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0220194 |
| CLMP | CXADR-like membrane protein | 0.0219635 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0218726 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.021678 |
| FNBP1L | formin binding protein 1-like | 0.0215974 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0215035 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0213956 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0213891 |
| MAP1B | microtubule-associated protein 1B | 0.0211578 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0209804 |
| COL4A1 | collagen, type IV, alpha 1 | 0.0209081 |
| SCFD2 | sec1 family domain containing 2 | 0.0207205 |
| MYLK | myosin light chain kinase | 0.0206377 |
| PCMT1 | protein-L-isoaspartate (D-aspartate) O-methyltransferase | 0.0204159 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0201987 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0201563 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 | 0.0201018 |
| RLF | rearranged L-myc fusion | 0.0200739 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | 0.0200528 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0199954 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0199887 |
| SCAF4 | SR-related CTD-associated factor 4 | 0.0197429 |
| DENND5A | DENN/MADD domain containing 5A | 0.0195597 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.155822 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.138683 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.118918 |
| TMSB10 | thymosin beta 10 | -0.118603 |
| VIM | vimentin | -0.0987191 |
| MT2A | metallothionein 2A | -0.0811922 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0741715 |
| HLA-B | major histocompatibility complex, class I, B | -0.0656517 |
| PRELID2 | PRELI domain containing 2 | -0.0652886 |
| FTL | ferritin, light polypeptide | -0.0625515 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0572697 |
| B2M | beta-2-microglobulin | -0.0531716 |
| RPS6 | ribosomal protein S6 | -0.0479773 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0468507 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0458201 |
| SEPTIN7 | septin 7 | -0.0435135 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0425561 |
| UBC | ubiquitin C | -0.0424827 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0411171 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | -0.0399646 |
| CANX | calnexin | -0.0393885 |
| POTEF | POTE ankyrin domain family, member F | -0.0387256 |
| PTMA | prothymosin, alpha | -0.0367685 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0366702 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.035506 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0344414 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0337821 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0336192 |
| EGR1 | early growth response 1 | -0.0335804 |
| RPL11 | ribosomal protein L11 | -0.0325332 |
| MATR3 | matrin 3 | -0.0320185 |
| RPS24 | ribosomal protein S24 | -0.0318302 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0307242 |
| RPL34 | ribosomal protein L34 | -0.0305583 |
| RPS23 | ribosomal protein S23 | -0.0300009 |
| RPS12 | ribosomal protein S12 | -0.0293043 |
| RRBP1 | ribosome binding protein 1 | -0.0292812 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0284526 |
| H3-3B | H3.3 histone B | -0.0283919 |
| HLA-C | major histocompatibility complex, class I, C | -0.0281831 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | -0.0281057 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0280951 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0280805 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0276458 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.026924 |
| GNAS | GNAS complex locus | -0.026768 |
| LMNA | lamin A/C | -0.026742 |
| RPS3 | ribosomal protein S3 | -0.0265454 |
| RACK1 | receptor for activated C kinase 1 | -0.0264691 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0258682 |
| TARS1 | threonyl-tRNA synthetase 1 | -0.0258312 |
| ZC3H15 | zinc finger CCCH-type containing 15 | -0.0257221 |
| ZNF395 | zinc finger protein 395 | -0.0257079 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0255984 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.025593 |
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | -0.0252197 |
| GLIS3 | GLIS family zinc finger 3 | -0.0249077 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0248161 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0248139 |
| CADM1 | cell adhesion molecule 1 | -0.0247283 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.024545 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0244977 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0243305 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0241929 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0239136 |
| PKM | pyruvate kinase, muscle | -0.0238329 |
| RPL37A | ribosomal protein L37a | -0.0231831 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0228861 |
| VCL | vinculin | -0.0225627 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.022505 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0223666 |
| RPL35A | ribosomal protein L35a | -0.0222714 |
| ATXN1 | ataxin 1 | -0.0220493 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0218494 |
| RPL36 | ribosomal protein L36 | -0.0218423 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0218199 |
| HPCAL1 | hippocalcin-like 1 | -0.0217532 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0217468 |
| CLIC4 | chloride intracellular channel 4 | -0.0210925 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0210522 |
| CLINT1 | clathrin interactor 1 | -0.0209449 |
| ENO1 | enolase 1, (alpha) | -0.0208895 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0207942 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0207919 |
| VEGFA | vascular endothelial growth factor A | -0.02074 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0206173 |
| SMYD3 | SET and MYND domain containing 3 | -0.0204891 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0202872 |
| NDFIP1 | Nedd4 family interacting protein 1 | -0.0202665 |
| SEC61G | Sec61 gamma subunit | -0.0202612 |
| TSPAN9 | tetraspanin 9 | -0.0201349 |
| JAG1 | jagged 1 | -0.0199525 |
| RPLP1 | ribosomal protein, large, P1 | -0.0197744 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0197499 |
| S100A9 | S100 calcium binding protein A9 | -0.0197176 |
| CENPF | centromere protein F, 350/400kDa | -0.0197127 |
| LDHA | lactate dehydrogenase A | -0.0196355 |
| ZFC3H1 | zinc finger, C3H1-type containing | -0.0194245 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0194188 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0194154 |
