| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Arbutin perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Arbutin_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RPL3 | ribosomal protein L3 | 0.0936222 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.077254 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.063599 |
| PCBP2 | poly(rC) binding protein 2 | 0.0616622 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0541976 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0529121 |
| AREG | amphiregulin | 0.0516751 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0505082 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.048514 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0452157 |
| PDGFC | platelet derived growth factor C | 0.044583 |
| TENM3 | teneurin transmembrane protein 3 | 0.0438714 |
| RPS19 | ribosomal protein S19 | 0.0428914 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0421158 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.0410174 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0409901 |
| TXNRD1 | thioredoxin reductase 1 | 0.0399853 |
| CRISPLD1 | cysteine-rich secretory protein LCCL domain containing 1 | 0.0397638 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0396965 |
| RRM2 | ribonucleotide reductase M2 | 0.0392875 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | 0.0385815 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0384047 |
| LDHA | lactate dehydrogenase A | 0.037932 |
| WWOX | WW domain containing oxidoreductase | 0.0369347 |
| RPL37 | ribosomal protein L37 | 0.0368668 |
| RPS4X | ribosomal protein S4, X-linked | 0.036203 |
| RTN4 | reticulon 4 | 0.036051 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0357225 |
| CPOX | coproporphyrinogen oxidase | 0.0333453 |
| RPL9 | ribosomal protein L9 | 0.0333025 |
| IPO7 | importin 7 | 0.0327723 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0325717 |
| TPM3 | tropomyosin 3 | 0.0325463 |
| RPS12 | ribosomal protein S12 | 0.0308771 |
| RPL27 | ribosomal protein L27 | 0.0306542 |
| NEK7 | NIMA-related kinase 7 | 0.0298572 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | 0.0295927 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0295132 |
| RPS6 | ribosomal protein S6 | 0.0293729 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0280193 |
| YEATS2 | YEATS domain containing 2 | 0.0274238 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.0272536 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0271631 |
| RPL4 | ribosomal protein L4 | 0.0263009 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0262795 |
| YAP1 | Yes-associated protein 1 | 0.0262264 |
| EPHA6 | EPH receptor A6 | 0.0260424 |
| PNN | pinin, desmosome associated protein | 0.0259143 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0254989 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0253251 |
| MSH6 | mutS homolog 6 | 0.0253176 |
| MYL12B | myosin, light chain 12B, regulatory | 0.0252024 |
| FEZ2 | fasciculation and elongation protein zeta 2 (zygin II) | 0.0251904 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0249843 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0248239 |
| APP | amyloid beta (A4) precursor protein | 0.0247929 |
| SS18 | synovial sarcoma translocation, chromosome 18 | 0.0246886 |
| ATP11A | ATPase, class VI, type 11A | 0.0243556 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0242715 |
| RPS27 | ribosomal protein S27 | 0.0241728 |
| FLNA | filamin A, alpha | 0.0237661 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0236761 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.023308 |
| MYO10 | myosin X | 0.0232068 |
| RPSA | ribosomal protein SA | 0.023173 |
| MATR3 | matrin 3 | 0.0230631 |
| MCL1 | myeloid cell leukemia 1 | 0.0230438 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 | 0.022957 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 | 0.0228524 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.022722 |
| RPL23 | ribosomal protein L23 | 0.0226411 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.0222874 |
| PSMD11 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 | 0.0222033 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0219412 |
| RPL11 | ribosomal protein L11 | 0.0217847 |
| YBX1 | Y box binding protein 1 | 0.0216613 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0216326 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0215951 |
| RPLP2 | ribosomal protein, large, P2 | 0.0214036 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0211405 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0210155 |
| THOC1 | THO complex 1 | 0.0209872 |
| PLEC | plectin | 0.0208195 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0207396 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0205421 |
| CCNL1 | cyclin L1 | 0.0204192 |
| RPLP0 | ribosomal protein, large, P0 | 0.0203891 |
| RPL7 | ribosomal protein L7 | 0.0203537 |
| CEP95 | centrosomal protein 95kDa | 0.0200654 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | 0.0199001 |
| AFG3L2 | AFG3-like AAA ATPase 2 | 0.0198998 |
| INCENP | inner centromere protein antigens 135/155kDa | 0.0195084 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0194817 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0193574 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0193283 |
| MED13L | mediator complex subunit 13-like | 0.0193076 |
| ATP5F1B | ATP synthase F1 subunit beta | 0.019303 |
| GASK1B | golgi associated kinase 1B | 0.0192752 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.019099 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.0190881 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.149775 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.143494 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.107274 |
| DST | dystonin | -0.0654285 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0635373 |
| EHBP1 | EH domain binding protein 1 | -0.0616188 |
| PTMA | prothymosin, alpha | -0.0600864 |
| NLGN1 | neuroligin 1 | -0.0564185 |
| HMGA2 | high mobility group AT-hook 2 | -0.0556878 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0524187 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0522128 |
| ZNF804A | zinc finger protein 804A | -0.0490155 |
| RASAL2 | RAS protein activator like 2 | -0.0474568 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0467234 |
| USP34 | ubiquitin specific peptidase 34 | -0.0445824 |
| S100A6 | S100 calcium binding protein A6 | -0.0438863 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0437604 |
| ADIPOR2 | adiponectin receptor 2 | -0.043235 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0429085 |
| ACTG1 | actin gamma 1 | -0.0418665 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0409358 |
| ANXA1 | annexin A1 | -0.0408752 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0399856 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0385511 |
| NF1 | neurofibromin 1 | -0.0384824 |
| EGR1 | early growth response 1 | -0.0375792 |
| JMJD1C | jumonji domain containing 1C | -0.0370525 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0362422 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0362175 |
| SSH2 | slingshot protein phosphatase 2 | -0.0354075 |
| MGAT4C | MGAT4 family, member C | -0.0346538 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0337953 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0326388 |
| CARD16 | caspase recruitment domain family, member 16 | -0.0325366 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0318169 |
| LARS1 | leucyl-tRNA synthetase 1 | -0.0312546 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0312339 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0309912 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0309022 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0307761 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0305232 |
| ZNF638 | zinc finger protein 638 | -0.0303754 |
| HMGA1 | high mobility group AT-hook 1 | -0.0301228 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0300502 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0300209 |
| DHX36 | DEAH (Asp-Glu-Ala-His) box polypeptide 36 | -0.0299692 |
| CENPF | centromere protein F, 350/400kDa | -0.0295912 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0294701 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0293244 |
| INTS6 | integrator complex subunit 6 | -0.0288115 |
| TMEM131 | transmembrane protein 131 | -0.0284132 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0282525 |
| CLDN1 | claudin 1 | -0.0280575 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | -0.0280005 |
| AFF4 | AF4/FMR2 family, member 4 | -0.027826 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0276934 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.027572 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | -0.0274217 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0273045 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0272674 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0270307 |
| SPAG9 | sperm associated antigen 9 | -0.0264622 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.0264369 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0263958 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.0262826 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | -0.0262394 |
| PCDH7 | protocadherin 7 | -0.0262014 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0260206 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0259759 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0259569 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0258569 |
| MAP4 | microtubule-associated protein 4 | -0.0256193 |
| CUX1 | cut-like homeobox 1 | -0.025408 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0252444 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0252365 |
| SPATS2 | spermatogenesis associated, serine-rich 2 | -0.024675 |
| RAB10 | RAB10, member RAS oncogene family | -0.0246064 |
| TPI1 | triosephosphate isomerase 1 | -0.0245245 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0244097 |
| EIF2AK1 | eukaryotic translation initiation factor 2-alpha kinase 1 | -0.0242317 |
| PA2G4 | proliferation-associated 2G4, 38kDa | -0.0240119 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0239343 |
| GPHN | gephyrin | -0.0238585 |
| JUN | jun proto-oncogene | -0.023843 |
| ELP4 | elongator acetyltransferase complex subunit 4 | -0.0238396 |
| FBXO11 | F-box protein 11 | -0.0237768 |
| PEG10 | paternally expressed 10 | -0.0237275 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0236458 |
| GOLGA4 | golgin A4 | -0.0235937 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0232181 |
| TAOK1 | TAO kinase 1 | -0.0231539 |
| RHOA | ras homolog family member A | -0.0231142 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | -0.0229859 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0229793 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0228771 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0228452 |
| NAV3 | neuron navigator 3 | -0.022762 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0227268 |
| ASXL2 | additional sex combs like transcriptional regulator 2 | -0.0225523 |
| PFN1 | profilin 1 | -0.022527 |
