| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Arbutin perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Arbutin_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| BTBD9 | BTB (POZ) domain containing 9 | 0.0948593 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0883139 |
| CANX | calnexin | 0.0878724 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0869012 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0861377 |
| LDHA | lactate dehydrogenase A | 0.0744305 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0663274 |
| VEGFA | vascular endothelial growth factor A | 0.0638307 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0635332 |
| PTEN | phosphatase and tensin homolog | 0.0589402 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | 0.0580772 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0544267 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0540707 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.0527307 |
| RUNX1 | runt-related transcription factor 1 | 0.0517992 |
| HDLBP | high density lipoprotein binding protein | 0.0496493 |
| SPATA13 | spermatogenesis associated 13 | 0.0490446 |
| MLPH | melanophilin | 0.0484197 |
| RPL3 | ribosomal protein L3 | 0.0480285 |
| DSPP | dentin sialophosphoprotein | 0.0475058 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | 0.0463773 |
| RNF43 | ring finger protein 43 | 0.046112 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0446152 |
| PADI1 | peptidyl arginine deiminase, type I | 0.0440252 |
| UBAC2 | UBA domain containing 2 | 0.0418916 |
| NDRG1 | N-myc downstream regulated 1 | 0.0416275 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0412484 |
| PRELID2 | PRELI domain containing 2 | 0.0411521 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0410174 |
| RNF149 | ring finger protein 149 | 0.0408496 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0404483 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | 0.0404299 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0396582 |
| H1-0 | H1.0 linker histone | 0.0393261 |
| ABHD2 | abhydrolase domain containing 2 | 0.038748 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0383632 |
| HYOU1 | hypoxia up-regulated 1 | 0.0382147 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0378004 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0376444 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0367176 |
| ADAR | adenosine deaminase, RNA-specific | 0.0365251 |
| RBM26 | RNA binding motif protein 26 | 0.0361778 |
| ARHGEF10L | Rho guanine nucleotide exchange factor (GEF) 10-like | 0.0359042 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0346113 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0345425 |
| STYXL2 | serine/threonine/tyrosine interacting like 2 | 0.0340191 |
| GOLGA4 | golgin A4 | 0.0337658 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.0337363 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0335525 |
| MSI2 | musashi RNA-binding protein 2 | 0.0327694 |
| EHF | ets homologous factor | 0.0325865 |
| GOLGB1 | golgin B1 | 0.0325207 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0323688 |
| ITGA6 | integrin, alpha 6 | 0.0321935 |
| AHNAK | AHNAK nucleoprotein | 0.0317003 |
| CMIP | c-Maf inducing protein | 0.0312425 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0311667 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0309382 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0304633 |
| COPA | coatomer protein complex, subunit alpha | 0.030423 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0303453 |
| MKI67 | marker of proliferation Ki-67 | 0.0302218 |
| FAT1 | FAT atypical cadherin 1 | 0.0299524 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0298834 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0298466 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0296403 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0295603 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0295084 |
| HDAC4 | histone deacetylase 4 | 0.0292739 |
| UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked | 0.0289174 |
| SORBS1 | sorbin and SH3 domain containing 1 | 0.0287844 |
| DNM2 | dynamin 2 | 0.028717 |
| RREB1 | ras responsive element binding protein 1 | 0.0286621 |
| CDK5RAP3 | CDK5 regulatory subunit associated protein 3 | 0.0284305 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.0283691 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0282677 |
| ERCC5 | excision repair cross-complementation group 5 | 0.0281054 |
| OARD1 | O-acyl-ADP-ribose deacylase 1 | 0.0280857 |
| TSPYL2 | TSPY-like 2 | 0.027739 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0276646 |
| MYO10 | myosin X | 0.0273964 |
| ZNRF3 | zinc and ring finger 3 | 0.027347 |
| YEATS2 | YEATS domain containing 2 | 0.0273297 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.026891 |
| SBF2 | SET binding factor 2 | 0.0268876 |
| LASP1 | LIM and SH3 protein 1 | 0.026564 |
| SH3PXD2A | SH3 and PX domains 2A | 0.0263516 |
| CDHR2 | cadherin-related family member 2 | 0.0262882 |
| NEBL | nebulette | 0.0261115 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0260517 |
| TRIM2 | tripartite motif containing 2 | 0.025961 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0259484 |
| KIF16B | kinesin family member 16B | 0.025577 |
| ALPK1 | alpha-kinase 1 | 0.0255192 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0252412 |
| TJP2 | tight junction protein 2 | 0.0252158 |
| ZNF148 | zinc finger protein 148 | 0.0251998 |
| RAD51B | RAD51 paralog B | 0.0251444 |
| LPCAT1 | lysophosphatidylcholine acyltransferase 1 | 0.0251376 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.02498 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TPT1 | tumor protein, translationally-controlled 1 | -0.201159 |
| B2M | beta-2-microglobulin | -0.150098 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.137105 |
| LCN2 | lipocalin 2 | -0.136809 |
| INTS6 | integrator complex subunit 6 | -0.132428 |
| EGR1 | early growth response 1 | -0.109988 |
| HLA-B | major histocompatibility complex, class I, B | -0.102695 |
| VCL | vinculin | -0.0817875 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0802718 |
| ANXA2 | annexin A2 | -0.0797823 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0752682 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0696221 |
| RPL35A | ribosomal protein L35a | -0.069138 |
| FTL | ferritin, light polypeptide | -0.0681763 |
| SP100 | SP100 nuclear antigen | -0.0647741 |
| RIGI | RNA sensor RIG-I | -0.0644335 |
| PLSCR2 | phospholipid scramblase 2 | -0.0635683 |
| PERP | PERP, TP53 apoptosis effector | -0.0635291 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0634659 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0604147 |
| TMSB10 | thymosin beta 10 | -0.0597925 |
| MX2 | MX dynamin-like GTPase 2 | -0.0590514 |
| AREG | amphiregulin | -0.0572243 |
| PLSCR1 | phospholipid scramblase 1 | -0.0570954 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0567465 |
| MYO1E | myosin IE | -0.0557792 |
| RNF213 | ring finger protein 213 | -0.054326 |
| PTMA | prothymosin, alpha | -0.053243 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0529964 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0512511 |
| STS | steroid sulfatase (microsomal), isozyme S | -0.0510694 |
| RPL34 | ribosomal protein L34 | -0.0509037 |
| ACTG1 | actin gamma 1 | -0.0507245 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0504659 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0500141 |
| XAF1 | XIAP associated factor 1 | -0.0496973 |
| MT2A | metallothionein 2A | -0.0494288 |
| TJP1 | tight junction protein 1 | -0.0493011 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0488288 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0484333 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0477985 |
| RPLP1 | ribosomal protein, large, P1 | -0.0474564 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0467003 |
| MUC20 | mucin 20, cell surface associated | -0.04635 |
| S100A10 | S100 calcium binding protein A10 | -0.0451224 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0449136 |
| RPS24 | ribosomal protein S24 | -0.0437313 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0432947 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0426897 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0415617 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0412878 |
| LMO7 | LIM domain 7 | -0.040821 |
| RPS6 | ribosomal protein S6 | -0.0401127 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0401108 |
| TM4SF19 | transmembrane 4 L six family member 19 | -0.0395438 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0395109 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0394018 |
| EFNB2 | ephrin-B2 | -0.0393312 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.039063 |
| RPS8 | ribosomal protein S8 | -0.0382507 |
| RPS19 | ribosomal protein S19 | -0.0368349 |
| TMC5 | transmembrane channel-like 5 | -0.0359365 |
| HLA-C | major histocompatibility complex, class I, C | -0.0358959 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.035676 |
| UBAP2 | ubiquitin associated protein 2 | -0.0346725 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0344421 |
| RPL23 | ribosomal protein L23 | -0.0343523 |
| LAMA4 | laminin, alpha 4 | -0.0340891 |
| POU2F2 | POU class 2 homeobox 2 | -0.0340196 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0333036 |
| RPL31 | ribosomal protein L31 | -0.0324858 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0320391 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0315434 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0313458 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0312305 |
| PMP22 | peripheral myelin protein 22 | -0.031204 |
| MAP7 | microtubule-associated protein 7 | -0.0308129 |
| VMP1 | vacuole membrane protein 1 | -0.030755 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0304783 |
| KLF6 | Kruppel-like factor 6 | -0.0301582 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0296397 |
| RPL7L1 | ribosomal protein L7-like 1 | -0.0293862 |
| POF1B | premature ovarian failure, 1B | -0.0286755 |
| RPL26 | ribosomal protein L26 | -0.0284789 |
| PKM | pyruvate kinase, muscle | -0.0283758 |
| RPL12 | ribosomal protein L12 | -0.0281036 |
| NABP1 | nucleic acid binding protein 1 | -0.0279139 |
| H3-3B | H3.3 histone B | -0.0276087 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.0275678 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0273797 |
| IER3 | immediate early response 3 | -0.0272773 |
| RPL37A | ribosomal protein L37a | -0.0272011 |
| RPL38 | ribosomal protein L38 | -0.0267265 |
| RPS29 | ribosomal protein S29 | -0.0265097 |
| RPL28 | ribosomal protein L28 | -0.0262829 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0261038 |
| FBXO39 | F-box protein 39 | -0.0258375 |
| RPLP2 | ribosomal protein, large, P2 | -0.0257513 |
| RPL36A | ribosomal protein L36a | -0.0252842 |
| RPLP0 | ribosomal protein, large, P0 | -0.0248635 |
