| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Arbutin perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Arbutin_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FLNB | filamin B, beta | 0.209424 |
| PLEC | plectin | 0.139025 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.134414 |
| RPL3 | ribosomal protein L3 | 0.0827813 |
| FLNA | filamin A, alpha | 0.0809471 |
| AHNAK | AHNAK nucleoprotein | 0.0763494 |
| MTSS1 | metastasis suppressor 1 | 0.0744404 |
| LDHA | lactate dehydrogenase A | 0.0698095 |
| MSN | moesin | 0.0693449 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0659905 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0641242 |
| BLCAP | bladder cancer associated protein | 0.0640542 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0601108 |
| SMAD3 | SMAD family member 3 | 0.0550761 |
| MCL1 | myeloid cell leukemia 1 | 0.0521423 |
| PODXL | podocalyxin-like | 0.0510973 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0495487 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0477029 |
| MYOF | myoferlin | 0.0466562 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0458324 |
| CPNE1 | copine I | 0.0456482 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0453636 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0449769 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 0.0446691 |
| ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif, 16 | 0.0443004 |
| APP | amyloid beta (A4) precursor protein | 0.0420164 |
| SULF1 | sulfatase 1 | 0.0419139 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0410351 |
| AMOTL1 | angiomotin like 1 | 0.0391909 |
| MEGF6 | multiple EGF-like-domains 6 | 0.0384412 |
| EHBP1L1 | EH domain binding protein 1-like 1 | 0.0379389 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0379039 |
| PRELID2 | PRELI domain containing 2 | 0.0365561 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0357211 |
| BCL2L1 | BCL2-like 1 | 0.0356544 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0354927 |
| RAI14 | retinoic acid induced 14 | 0.034812 |
| TGM2 | transglutaminase 2 | 0.0339601 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0336713 |
| HDLBP | high density lipoprotein binding protein | 0.0335096 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0329983 |
| TPM3 | tropomyosin 3 | 0.0324324 |
| CEP250 | centrosomal protein 250kDa | 0.0320601 |
| FOXO1 | forkhead box O1 | 0.031925 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0315577 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0315239 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0313021 |
| LMO7 | LIM domain 7 | 0.0312146 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0308788 |
| CANX | calnexin | 0.0304464 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0298096 |
| PRSS23 | protease, serine, 23 | 0.0294125 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0290368 |
| ACTN1 | actinin, alpha 1 | 0.0286511 |
| MYO10 | myosin X | 0.0283726 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0282387 |
| ARHGAP23 | Rho GTPase activating protein 23 | 0.0280209 |
| ANXA11 | annexin A11 | 0.0272245 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.0268766 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0266453 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.026536 |
| LAMC2 | laminin, gamma 2 | 0.0262246 |
| OSMR | oncostatin M receptor | 0.0261464 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0252165 |
| NEK7 | NIMA-related kinase 7 | 0.0252134 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0250564 |
| DIDO1 | death inducer-obliterator 1 | 0.0246911 |
| AOPEP | aminopeptidase O (putative) | 0.0240802 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0238755 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0232992 |
| CUL4B | cullin 4B | 0.0232035 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0231521 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0228958 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0228692 |
| KIAA1217 | KIAA1217 | 0.0225389 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | 0.0225325 |
| CAPRIN2 | caprin family member 2 | 0.0225202 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0223484 |
| RIN2 | Ras and Rab interactor 2 | 0.0222915 |
| ASPH | aspartate beta-hydroxylase | 0.0222061 |
| SEPTIN9 | septin 9 | 0.0217573 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0215097 |
| SULF2 | sulfatase 2 | 0.0214127 |
| NAV2 | neuron navigator 2 | 0.0213572 |
| RPL18A | ribosomal protein L18a | 0.0212226 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0211471 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0211373 |
| RBM39 | RNA binding motif protein 39 | 0.0210223 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0209052 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 0.0206935 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0206899 |
| NTSR1 | neurotensin receptor 1 (high affinity) | 0.0205834 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0204329 |
| SDHA | succinate dehydrogenase complex, subunit A, flavoprotein (Fp) | 0.020167 |
| EXOC4 | exocyst complex component 4 | 0.0200505 |
| ITGA6 | integrin, alpha 6 | 0.0200243 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | 0.019606 |
| DOK5 | docking protein 5 | 0.0195893 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | 0.019574 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0195358 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.228281 |
| TMSB10 | thymosin beta 10 | -0.119449 |
| B2M | beta-2-microglobulin | -0.108945 |
| MT2A | metallothionein 2A | -0.0999907 |
| S100A10 | S100 calcium binding protein A10 | -0.0934539 |
| RPS6 | ribosomal protein S6 | -0.0905277 |
| PTMA | prothymosin, alpha | -0.0899554 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0679244 |
| NDRG1 | N-myc downstream regulated 1 | -0.0665552 |
| RPLP2 | ribosomal protein, large, P2 | -0.0642529 |
| RPS21 | ribosomal protein S21 | -0.0631111 |
| RPS8 | ribosomal protein S8 | -0.0590236 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0578998 |
| IGF2 | insulin-like growth factor 2 | -0.0565416 |
| RPS13 | ribosomal protein S13 | -0.0552578 |
| POTEF | POTE ankyrin domain family, member F | -0.0531665 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.052873 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0513695 |
| RPLP1 | ribosomal protein, large, P1 | -0.0512188 |
| FTL | ferritin, light polypeptide | -0.0505366 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0503239 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0482653 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.047138 |
| S100A6 | S100 calcium binding protein A6 | -0.0469443 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0468502 |
| RPS19 | ribosomal protein S19 | -0.0466671 |
| STC1 | stanniocalcin 1 | -0.046399 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0463514 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0434413 |
| S100A9 | S100 calcium binding protein A9 | -0.0425141 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0423901 |
| RPS24 | ribosomal protein S24 | -0.0422915 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0403683 |
| MT1X | metallothionein 1X | -0.039483 |
| S100A11 | S100 calcium binding protein A11 | -0.0394739 |
| RPS25 | ribosomal protein S25 | -0.0393937 |
| WASF2 | WAS protein family, member 2 | -0.0391805 |
| RPL12 | ribosomal protein L12 | -0.0390987 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0383909 |
| ANXA1 | annexin A1 | -0.0381807 |
| HLA-B | major histocompatibility complex, class I, B | -0.0380883 |
| RPL35A | ribosomal protein L35a | -0.0369767 |
| DSTN | destrin (actin depolymerizing factor) | -0.0356314 |
| RPS23 | ribosomal protein S23 | -0.0353306 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.035181 |
| RPL34 | ribosomal protein L34 | -0.0345237 |
| RPS3 | ribosomal protein S3 | -0.0342582 |
| RPL31 | ribosomal protein L31 | -0.0334718 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0334378 |
| RPLP0 | ribosomal protein, large, P0 | -0.0325954 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0314585 |
| PFN1 | profilin 1 | -0.0312441 |
| S100A2 | S100 calcium binding protein A2 | -0.0312052 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0311838 |
| FSCN1 | fascin actin-bundling protein 1 | -0.0310394 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0310108 |
| RACK1 | receptor for activated C kinase 1 | -0.0304608 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0303173 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0301702 |
| RPL37A | ribosomal protein L37a | -0.0296477 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0296312 |
| RPS14 | ribosomal protein S14 | -0.0296306 |
| RPL32 | ribosomal protein L32 | -0.029596 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0295055 |
| TXNIP | thioredoxin interacting protein | -0.0294865 |
| SEPTIN7 | septin 7 | -0.0289405 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0282157 |
| RPL36 | ribosomal protein L36 | -0.0281843 |
| RPS29 | ribosomal protein S29 | -0.0281617 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0281542 |
| RPL36A | ribosomal protein L36a | -0.0279741 |
| RPL7A | ribosomal protein L7a | -0.0274274 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0274069 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0272815 |
| RPS12 | ribosomal protein S12 | -0.0270964 |
| RPS27 | ribosomal protein S27 | -0.0269503 |
| RPL28 | ribosomal protein L28 | -0.0266554 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0265037 |
| GOLGA4 | golgin A4 | -0.0264894 |
| LMNA | lamin A/C | -0.0262227 |
| RPL23 | ribosomal protein L23 | -0.0260794 |
| FNDC3A | fibronectin type III domain containing 3A | -0.026068 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0256699 |
| RPL35 | ribosomal protein L35 | -0.0255304 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0255188 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0254861 |
| RPL27A | ribosomal protein L27a | -0.0252495 |
| RIOK3 | RIO kinase 3 | -0.0251976 |
| RPS16 | ribosomal protein S16 | -0.0249123 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.024802 |
| CLU | clusterin | -0.0246475 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0245603 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0244334 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0242127 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0241907 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0239081 |
| PKM | pyruvate kinase, muscle | -0.0237705 |
| RPL8 | ribosomal protein L8 | -0.0237647 |
| CCNI | cyclin I | -0.0237637 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.0229726 |