| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Arbutin perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Arbutin_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.206642 |
| LDHA | lactate dehydrogenase A | 0.138913 |
| RPL3 | ribosomal protein L3 | 0.130081 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.10706 |
| GOLGA4 | golgin A4 | 0.105998 |
| KRT18 | keratin 18, type I | 0.102939 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0982101 |
| VEGFA | vascular endothelial growth factor A | 0.0913201 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0834503 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0784133 |
| FAM13A | family with sequence similarity 13, member A | 0.0739514 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0736021 |
| FAT1 | FAT atypical cadherin 1 | 0.0728369 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0716469 |
| CANX | calnexin | 0.0680305 |
| HDLBP | high density lipoprotein binding protein | 0.0653561 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0647403 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0630493 |
| NDRG1 | N-myc downstream regulated 1 | 0.0629505 |
| DSPP | dentin sialophosphoprotein | 0.0599577 |
| MED13L | mediator complex subunit 13-like | 0.0561216 |
| RBM39 | RNA binding motif protein 39 | 0.0557746 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0556832 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0555396 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0537132 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0535876 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0534056 |
| EREG | epiregulin | 0.0514591 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0500426 |
| RNF43 | ring finger protein 43 | 0.0474224 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0472807 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | 0.0465666 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | 0.0462523 |
| CALR | calreticulin | 0.046049 |
| FLNB | filamin B, beta | 0.0458063 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0456845 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0454944 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0452945 |
| OGA | O-GlcNAcase | 0.0449547 |
| RNF145 | ring finger protein 145 | 0.0448711 |
| COG5 | component of oligomeric golgi complex 5 | 0.0439649 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0436772 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0430928 |
| PTEN | phosphatase and tensin homolog | 0.0429368 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.042659 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0421678 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | 0.0421481 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0416317 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0411311 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0400445 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.040037 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0400295 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.039014 |
| H1-0 | H1.0 linker histone | 0.0387698 |
| PRSS3 | protease, serine, 3 | 0.0387087 |
| ITGA6 | integrin, alpha 6 | 0.0385424 |
| DNM2 | dynamin 2 | 0.0383707 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.038314 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0381047 |
| KRT8 | keratin 8, type II | 0.0379937 |
| PLEC | plectin | 0.0376318 |
| YME1L1 | YME1-like 1 ATPase | 0.0374966 |
| YTHDC1 | YTH domain containing 1 | 0.0370358 |
| SETD5 | SET domain containing 5 | 0.0368653 |
| RREB1 | ras responsive element binding protein 1 | 0.0358428 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0357333 |
| NEBL | nebulette | 0.035672 |
| KIF5B | kinesin family member 5B | 0.0356349 |
| LMO7 | LIM domain 7 | 0.035626 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0354864 |
| DERA | deoxyribose-phosphate aldolase (putative) | 0.0353343 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0349965 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.0348249 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0346529 |
| TPM3 | tropomyosin 3 | 0.0344962 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0344352 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0342469 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0341943 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0341202 |
| FNDC3B | fibronectin type III domain containing 3B | 0.034063 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0336453 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0333401 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.03331 |
| ZNF292 | zinc finger protein 292 | 0.0331898 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0330983 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0328866 |
| SLC35A3 | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 | 0.0327319 |
| PIGR | polymeric immunoglobulin receptor | 0.0325675 |
| USP3 | ubiquitin specific peptidase 3 | 0.0325627 |
| CCNY | cyclin Y | 0.0325352 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.032408 |
| APP | amyloid beta (A4) precursor protein | 0.0317641 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.031751 |
| TMSB4X | thymosin beta 4, X-linked | 0.0317102 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0316567 |
| AFDN | afadin, adherens junction formation factor | 0.0316147 |
| TXNIP | thioredoxin interacting protein | 0.0315644 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0314637 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0309716 |
| CARS1 | cysteinyl-tRNA synthetase 1 | 0.0307326 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.155236 |
| NPSR1 | neuropeptide S receptor 1 | -0.149154 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.120778 |
| PTMA | prothymosin, alpha | -0.074632 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0705037 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.065973 |
| MYO1E | myosin IE | -0.0644987 |
| ACTG1 | actin gamma 1 | -0.0525374 |
| VCL | vinculin | -0.0507836 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0466028 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0463464 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0425728 |
| LAMA4 | laminin, alpha 4 | -0.0424327 |
| MT2A | metallothionein 2A | -0.0386778 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0385384 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0384307 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0381221 |
| RPS6 | ribosomal protein S6 | -0.037642 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0371198 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0354093 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0351077 |
| RPLP1 | ribosomal protein, large, P1 | -0.0347352 |
| EGFR | epidermal growth factor receptor | -0.0338081 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0336817 |
| FHIT | fragile histidine triad | -0.033094 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0324647 |
| RPS19 | ribosomal protein S19 | -0.0322776 |
| RPS8 | ribosomal protein S8 | -0.03036 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.0262264 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | -0.025548 |
| RPL35A | ribosomal protein L35a | -0.0253434 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0252381 |
| CADPS | Ca++-dependent secretion activator | -0.0252142 |
| POF1B | premature ovarian failure, 1B | -0.0249669 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.0248268 |
| CLOCK | clock circadian regulator | -0.0248162 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.024652 |
| RNF217 | ring finger protein 217 | -0.02421 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0241038 |
| RPL9 | ribosomal protein L9 | -0.0240088 |
| RPL36 | ribosomal protein L36 | -0.0236365 |
| IER3 | immediate early response 3 | -0.0234859 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.02323 |
| EGR1 | early growth response 1 | -0.0231749 |
| DIAPH3 | diaphanous-related formin 3 | -0.0230652 |
| RPL34 | ribosomal protein L34 | -0.0220326 |
| RAD51B | RAD51 paralog B | -0.0219536 |
| HMGA1 | high mobility group AT-hook 1 | -0.0218752 |
| EHBP1 | EH domain binding protein 1 | -0.0217903 |
| POTEF | POTE ankyrin domain family, member F | -0.0217406 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0210387 |
| RPS29 | ribosomal protein S29 | -0.0207238 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0204296 |
| S100A10 | S100 calcium binding protein A10 | -0.020092 |
| B4GALNT3 | beta-1,4-N-acetyl-galactosaminyl transferase 3 | -0.0200507 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0197364 |
| RPL32 | ribosomal protein L32 | -0.0196461 |
| HMGB1 | high mobility group box 1 | -0.0192155 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0192136 |
| MT1X | metallothionein 1X | -0.0191972 |
| SVIL | supervillin | -0.0191474 |
| MARCHF3 | membrane associated ring-CH-type finger 3 | -0.0190429 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0186043 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0181907 |
| ONECUT3 | one cut homeobox 3 | -0.0181373 |
| RPLP2 | ribosomal protein, large, P2 | -0.0180381 |
| MT1E | metallothionein 1E | -0.0179559 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0179491 |
| RPL31 | ribosomal protein L31 | -0.0179109 |
| DIAPH2 | diaphanous-related formin 2 | -0.0178036 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.0178033 |
| SOX9 | SRY (sex determining region Y)-box 9 | -0.0176724 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.017654 |
| FTL | ferritin, light polypeptide | -0.0171263 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0171015 |
| LSAMP | limbic system-associated membrane protein | -0.0170489 |
| RPL37A | ribosomal protein L37a | -0.0170081 |
| EXOC4 | exocyst complex component 4 | -0.0169445 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0169411 |
| RPL28 | ribosomal protein L28 | -0.0168523 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0164763 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0162958 |
| INTS6 | integrator complex subunit 6 | -0.0161246 |
| PCDH9 | protocadherin 9 | -0.0160691 |
| SH3D19 | SH3 domain containing 19 | -0.0160114 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0157359 |
| RIN2 | Ras and Rab interactor 2 | -0.0156565 |
| NRN1 | neuritin 1 | -0.0156452 |
| NBEAL1 | neurobeachin-like 1 | -0.0154875 |
| TUBA1B | tubulin, alpha 1b | -0.0153878 |
| LOC112694756 | uncharaterized LOC112694756 | -0.015376 |
| PFN1 | profilin 1 | -0.0152363 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0150636 |
| CENPE | centromere protein E, 312kDa | -0.0148899 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0148699 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) | -0.0147486 |
| RPL35 | ribosomal protein L35 | -0.0147408 |
| EMP1 | epithelial membrane protein 1 | -0.0147397 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | -0.0147049 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0145871 |
