| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Arbutin perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Arbutin_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | 0.131364 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.130342 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.122671 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.119704 |
| RPL13A | ribosomal protein L13a | 0.0975036 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0970982 |
| GNAS | GNAS complex locus | 0.0915221 |
| FAM13A | family with sequence similarity 13, member A | 0.0913252 |
| CANX | calnexin | 0.0900402 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.085521 |
| NDRG1 | N-myc downstream regulated 1 | 0.0853081 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0806622 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0779659 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0769369 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.076309 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0755606 |
| PTK2 | protein tyrosine kinase 2 | 0.0751968 |
| RPS6 | ribosomal protein S6 | 0.0700044 |
| RPS8 | ribosomal protein S8 | 0.065854 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.06552 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0651425 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0635201 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0616229 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0608353 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0603514 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0602577 |
| LDHA | lactate dehydrogenase A | 0.0597527 |
| RPLP1 | ribosomal protein, large, P1 | 0.0597249 |
| RPL4 | ribosomal protein L4 | 0.0593108 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0587343 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | 0.0586967 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.058139 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0579974 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0553976 |
| AREG | amphiregulin | 0.0552531 |
| MT2A | metallothionein 2A | 0.0541146 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | 0.0535668 |
| PLAU | plasminogen activator, urokinase | 0.0526965 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0523694 |
| RNF145 | ring finger protein 145 | 0.0523168 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0519171 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.051702 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0516772 |
| ATP11A | ATPase, class VI, type 11A | 0.0512794 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0502107 |
| GPHN | gephyrin | 0.0501832 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0498879 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0495433 |
| RPL19 | ribosomal protein L19 | 0.048612 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.047858 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | 0.0472738 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0469032 |
| RPS3 | ribosomal protein S3 | 0.0464754 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0462548 |
| PGK1 | phosphoglycerate kinase 1 | 0.0447604 |
| OGA | O-GlcNAcase | 0.0444128 |
| GCC2 | GRIP and coiled-coil domain containing 2 | 0.0441697 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0440137 |
| USP8 | ubiquitin specific peptidase 8 | 0.0433151 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0430891 |
| PDE10A | phosphodiesterase 10A | 0.0428332 |
| RLF | rearranged L-myc fusion | 0.0422027 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | 0.0421188 |
| LRP12 | low density lipoprotein receptor-related protein 12 | 0.0419956 |
| TPM3 | tropomyosin 3 | 0.0415975 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | 0.0415522 |
| RPS11 | ribosomal protein S11 | 0.041409 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0413238 |
| RBM6 | RNA binding motif protein 6 | 0.0411767 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0410394 |
| DDX56 | DEAD (Asp-Glu-Ala-Asp) box helicase 56 | 0.0410227 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | 0.0409483 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0408139 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0406747 |
| THRAP3 | thyroid hormone receptor associated protein 3 | 0.0406671 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0405682 |
| IFRD1 | interferon-related developmental regulator 1 | 0.040462 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0402539 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0399784 |
| COPA | coatomer protein complex, subunit alpha | 0.039916 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0396824 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.038826 |
| APP | amyloid beta (A4) precursor protein | 0.0382295 |
| RPS20 | ribosomal protein S20 | 0.038081 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0380039 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0376553 |
| RPL11 | ribosomal protein L11 | 0.0375862 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0373564 |
| ACTG1 | actin gamma 1 | 0.0362022 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0360727 |
| SMAD3 | SMAD family member 3 | 0.035734 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0357305 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0355822 |
| SPAG9 | sperm associated antigen 9 | 0.0345694 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.033723 |
| TPD52 | tumor protein D52 | 0.0332046 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0322323 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0321597 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0319469 |
| ADAR | adenosine deaminase, RNA-specific | 0.0318123 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.123395 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.105854 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.100486 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0966958 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0962272 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.094268 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0922349 |
| AHNAK | AHNAK nucleoprotein | -0.0905006 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0884579 |
| ATOSA | atos homolog A | -0.0868473 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0848236 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0827073 |
| MAPK6 | mitogen-activated protein kinase 6 | -0.0819626 |
| ABHD17C | abhydrolase domain containing 17C | -0.0816566 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0797443 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0795385 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0792023 |
| EFNA5 | ephrin-A5 | -0.0791721 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0781565 |
| MYOF | myoferlin | -0.0761355 |
| ANXA2 | annexin A2 | -0.0756012 |
| KIAA1671 | KIAA1671 | -0.0744516 |
| MYO1E | myosin IE | -0.0738853 |
| HOOK3 | hook microtubule-tethering protein 3 | -0.0734734 |
| WASF2 | WAS protein family, member 2 | -0.0722197 |
| LAMB3 | laminin, beta 3 | -0.0690576 |
| NEBL | nebulette | -0.0680674 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0665792 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0664857 |
| KIAA1217 | KIAA1217 | -0.0656063 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.064446 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0643126 |
| DOCK5 | dedicator of cytokinesis 5 | -0.063727 |
| USP53 | ubiquitin specific peptidase 53 | -0.0630152 |
| TANK | TRAF family member-associated NFKB activator | -0.0620479 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0619191 |
| LNPEP | leucyl/cystinyl aminopeptidase | -0.0612543 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0583632 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0580638 |
| PARD3 | par-3 family cell polarity regulator | -0.0580406 |
| MUC16 | mucin 16, cell surface associated | -0.0578311 |
| RIGI | RNA sensor RIG-I | -0.0576656 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0569965 |
| DSG2 | desmoglein 2 | -0.0551972 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0546294 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.0543305 |
| NBEA | neurobeachin | -0.0541745 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0532943 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0515403 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | -0.0501968 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0497066 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0495506 |
| NCOR1 | nuclear receptor corepressor 1 | -0.048968 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0489198 |
| NUMB | numb homolog (Drosophila) | -0.0486679 |
| S100A9 | S100 calcium binding protein A9 | -0.0486213 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0480777 |
| SMYD3 | SET and MYND domain containing 3 | -0.047992 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0476946 |
| FN1 | fibronectin 1 | -0.0476315 |
| SVIL | supervillin | -0.0463397 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0460062 |
| RUFY1 | RUN and FYVE domain containing 1 | -0.0458285 |
| UBC | ubiquitin C | -0.0456814 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0455995 |
| RPL31 | ribosomal protein L31 | -0.0451277 |
| RCOR1 | REST corepressor 1 | -0.0448531 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0436674 |
| RPL15 | ribosomal protein L15 | -0.0425947 |
| SEC24D | SEC24 family member D | -0.0424889 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0424818 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0423742 |
| CD99 | CD99 molecule | -0.0416686 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0411568 |
| KATNBL1 | katanin p80 subunit B-like 1 | -0.041069 |
| KRT17 | keratin 17, type I | -0.0409651 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0399301 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0395759 |
| S100A6 | S100 calcium binding protein A6 | -0.0393684 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0393391 |
| HLA-B | major histocompatibility complex, class I, B | -0.0393097 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0390997 |
| PHF21A | PHD finger protein 21A | -0.0385177 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0385046 |
| PRELID2 | PRELI domain containing 2 | -0.0384237 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0383692 |
| SAR1A | secretion associated, Ras related GTPase 1A | -0.0379412 |
| MXD1 | MAX dimerization protein 1 | -0.0369926 |
| FOXO3 | forkhead box O3 | -0.036936 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0368643 |
| TMSB10 | thymosin beta 10 | -0.0354962 |
| POTEF | POTE ankyrin domain family, member F | -0.0353897 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0350416 |
| ARHGAP21 | Rho GTPase activating protein 21 | -0.0343419 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0337938 |
| GOLGB1 | golgin B1 | -0.0334531 |
| TPM4 | tropomyosin 4 | -0.0331255 |
| WDR45B | WD repeat domain 45B | -0.0329613 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0329317 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0328558 |
