| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Arbutin perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Arbutin_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.212326 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.182086 |
| THBS1 | thrombospondin 1 | 0.120581 |
| RPL3 | ribosomal protein L3 | 0.11714 |
| LDHA | lactate dehydrogenase A | 0.109027 |
| TMSB4X | thymosin beta 4, X-linked | 0.108979 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.104189 |
| PTMA | prothymosin, alpha | 0.104126 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.102356 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0983652 |
| MKI67 | marker of proliferation Ki-67 | 0.0917853 |
| CALR | calreticulin | 0.0884566 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0880992 |
| CANX | calnexin | 0.082996 |
| COL5A2 | collagen, type V, alpha 2 | 0.0808788 |
| COL1A2 | collagen, type I, alpha 2 | 0.0796905 |
| APP | amyloid beta (A4) precursor protein | 0.078258 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0718329 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0674668 |
| SET | SET nuclear proto-oncogene | 0.0666078 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0663748 |
| SPAG9 | sperm associated antigen 9 | 0.0654777 |
| MYL12B | myosin, light chain 12B, regulatory | 0.0631234 |
| COL3A1 | collagen, type III, alpha 1 | 0.0621432 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0617049 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0612958 |
| RPS4X | ribosomal protein S4, X-linked | 0.0611499 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.06111 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0594695 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0582605 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0582245 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0578876 |
| RPL11 | ribosomal protein L11 | 0.0574835 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0552752 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 0.0524462 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0515129 |
| CENPF | centromere protein F, 350/400kDa | 0.0502865 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0502593 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0487384 |
| TPM3 | tropomyosin 3 | 0.0475456 |
| GNAS | GNAS complex locus | 0.0475278 |
| YBX1 | Y box binding protein 1 | 0.0467343 |
| H1-4 | H1.4 linker histone, cluster member | 0.0464825 |
| RPL13A | ribosomal protein L13a | 0.0460119 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0452948 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0448497 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0447529 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.0443721 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0441628 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.0441417 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0434083 |
| HDLBP | high density lipoprotein binding protein | 0.0421152 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.041993 |
| COTL1 | coactosin-like F-actin binding protein 1 | 0.0419685 |
| RPL4 | ribosomal protein L4 | 0.0418344 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.0416164 |
| ILF3 | interleukin enhancer binding factor 3, 90kDa | 0.0415947 |
| CPNE1 | copine I | 0.0412697 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0410526 |
| WDR43 | WD repeat domain 43 | 0.0405338 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0396185 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.039441 |
| AHNAK | AHNAK nucleoprotein | 0.0394386 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0391745 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0390075 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | 0.038202 |
| RBM39 | RNA binding motif protein 39 | 0.0378812 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0376711 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.037415 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0370428 |
| MB21D2 | Mab-21 domain containing 2 | 0.0368473 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0367638 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0361596 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0360464 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0359796 |
| PGAP1 | post-GPI attachment to proteins 1 | 0.0358978 |
| ANXA1 | annexin A1 | 0.0352716 |
| HMGB2 | high mobility group box 2 | 0.0352117 |
| RDX | radixin | 0.0351774 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | 0.0346903 |
| KIF5B | kinesin family member 5B | 0.0344773 |
| FIP1L1 | factor interacting with PAPOLA and CPSF1 | 0.0341551 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 | 0.0341371 |
| RLF | rearranged L-myc fusion | 0.033687 |
| CALU | calumenin | 0.0328381 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0327099 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0326759 |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | 0.03261 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0324204 |
| NONO | non-POU domain containing, octamer-binding | 0.0322082 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0321604 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0321598 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B | 0.0321394 |
| ABCF1 | ATP-binding cassette, sub-family F (GCN20), member 1 | 0.0319665 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0319389 |
| EIF3B | eukaryotic translation initiation factor 3, subunit B | 0.0317116 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0313214 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0312752 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.0311934 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0311119 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.074845 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0669153 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0566012 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0521071 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0475036 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.043172 |
| MED13L | mediator complex subunit 13-like | -0.0427401 |
| PHIP | pleckstrin homology domain interacting protein | -0.0419765 |
| USP34 | ubiquitin specific peptidase 34 | -0.0407852 |
| FTL | ferritin, light polypeptide | -0.0388616 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | -0.0381441 |
| NTM | neurotrimin | -0.0352384 |
| PFN1 | profilin 1 | -0.0347121 |
| ADNP | activity-dependent neuroprotector homeobox | -0.034707 |
| PRR16 | proline rich 16 | -0.0334899 |
| ZNF638 | zinc finger protein 638 | -0.0319673 |
| TUBA1B | tubulin, alpha 1b | -0.0304428 |
| TMOD3 | tropomodulin 3 (ubiquitous) | -0.0304053 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0296162 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0294098 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.029258 |
| HMGA1 | high mobility group AT-hook 1 | -0.0286233 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0286039 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0283569 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.0278783 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0274605 |
| LRRC4C | leucine rich repeat containing 4C | -0.0269482 |
| TENM3 | teneurin transmembrane protein 3 | -0.0268696 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0268209 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0267988 |
| PCDH9 | protocadherin 9 | -0.0265787 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0264179 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0261849 |
| BMPR1A | bone morphogenetic protein receptor, type IA | -0.0261222 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0259941 |
| R3HDM1 | R3H domain containing 1 | -0.0259842 |
| BBX | bobby sox homolog (Drosophila) | -0.0259389 |
| TOX | thymocyte selection-associated high mobility group box | -0.0258037 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0257342 |
| NCOA2 | nuclear receptor coactivator 2 | -0.0252976 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0251758 |
| WASF2 | WAS protein family, member 2 | -0.0251281 |
| CADM2 | cell adhesion molecule 2 | -0.0250924 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0250629 |
| SKIC3 | SKI3 subunit of superkiller complex | -0.0249051 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0247921 |
| JMJD1C | jumonji domain containing 1C | -0.024758 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.024572 |
| RAD51B | RAD51 paralog B | -0.024553 |
| UBE2R2 | ubiquitin-conjugating enzyme E2R 2 | -0.0245406 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0244867 |
| RPL35A | ribosomal protein L35a | -0.0244703 |
| RPS6 | ribosomal protein S6 | -0.0244414 |
| PLCB4 | phospholipase C, beta 4 | -0.0244118 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0243305 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0242812 |
| CRISPLD1 | cysteine-rich secretory protein LCCL domain containing 1 | -0.0241893 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0241524 |
| MT2A | metallothionein 2A | -0.0236993 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.023471 |
| FN1 | fibronectin 1 | -0.0230465 |
| CREBBP | CREB binding protein | -0.0229009 |
| VIM | vimentin | -0.0228143 |
| POTEF | POTE ankyrin domain family, member F | -0.0228001 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | -0.0223969 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0223386 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0220698 |
| ADGRL3 | adhesion G protein-coupled receptor L3 | -0.0219174 |
| PARD3 | par-3 family cell polarity regulator | -0.0218979 |
| NEBL | nebulette | -0.0216869 |
| CDYL | chromodomain protein, Y-like | -0.0215751 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.0215593 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0214112 |
| TCF12 | transcription factor 12 | -0.0210721 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0210184 |
| ARHGAP24 | Rho GTPase activating protein 24 | -0.0209443 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | -0.0207517 |
| ACAP2 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 | -0.0206899 |
| HS3ST5 | heparan sulfate (glucosamine) 3-O-sulfotransferase 5 | -0.0204841 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0203726 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0203132 |
| ITGAV | integrin, alpha V | -0.0202807 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0201842 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0201551 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0201335 |
| PTEN | phosphatase and tensin homolog | -0.0200998 |
| SNAPC1 | small nuclear RNA activating complex, polypeptide 1, 43kDa | -0.0200958 |
| ZMYM4 | zinc finger, MYM-type 4 | -0.0200517 |
| SETD5 | SET domain containing 5 | -0.0199601 |
| IER3 | immediate early response 3 | -0.0198111 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.0197409 |
| RFX7 | regulatory factor X, 7 | -0.0196889 |
| SGO2 | shugoshin 2 | -0.0196719 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0193217 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0193133 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0192261 |
| SKIL | SKI-like proto-oncogene | -0.0192102 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.019042 |
| MAGT1 | magnesium transporter 1 | -0.0189598 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0187761 |
