| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Arbutin perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Arbutin_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SOD2 | superoxide dismutase 2, mitochondrial | 0.307111 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.275442 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.156856 |
| COL6A3 | collagen, type VI, alpha 3 | 0.156618 |
| FRMD4A | FERM domain containing 4A | 0.148902 |
| FN1 | fibronectin 1 | 0.115775 |
| LDHA | lactate dehydrogenase A | 0.0884237 |
| NAV2 | neuron navigator 2 | 0.0768091 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0712899 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0666869 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0637194 |
| SMAD3 | SMAD family member 3 | 0.060626 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0593161 |
| FLNA | filamin A, alpha | 0.0570384 |
| RPL3 | ribosomal protein L3 | 0.0569348 |
| THBS1 | thrombospondin 1 | 0.055965 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0533457 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0521724 |
| AHNAK | AHNAK nucleoprotein | 0.0516122 |
| C3 | complement component 3 | 0.0511292 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.049549 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0490345 |
| MSN | moesin | 0.048894 |
| APP | amyloid beta (A4) precursor protein | 0.0486003 |
| CEP250 | centrosomal protein 250kDa | 0.0460336 |
| TUBB | tubulin, beta class I | 0.0439605 |
| FLNB | filamin B, beta | 0.0430306 |
| MLPH | melanophilin | 0.0415017 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | 0.0406038 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0397083 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0385506 |
| TNS3 | tensin 3 | 0.0378049 |
| MYOF | myoferlin | 0.0377055 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0362393 |
| OGA | O-GlcNAcase | 0.0362075 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0355356 |
| FAM20C | family with sequence similarity 20, member C | 0.0350786 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0350569 |
| ANLN | anillin, actin binding protein | 0.0339352 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | 0.0338711 |
| OPTN | optineurin | 0.0328884 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0314122 |
| TPM4 | tropomyosin 4 | 0.0312013 |
| MKI67 | marker of proliferation Ki-67 | 0.0307712 |
| ACTN1 | actinin, alpha 1 | 0.0306872 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0301713 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0297581 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0291744 |
| RIGI | RNA sensor RIG-I | 0.0290758 |
| RNF213 | ring finger protein 213 | 0.0290449 |
| DST | dystonin | 0.028825 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0286876 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.0285998 |
| UTRN | utrophin | 0.0285987 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.028275 |
| PLEC | plectin | 0.0282046 |
| SFTPA2 | surfactant protein A2 | 0.0274991 |
| IGF2R | insulin-like growth factor 2 receptor | 0.0274887 |
| MCL1 | myeloid cell leukemia 1 | 0.0270593 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0265136 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0262509 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0260401 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.025779 |
| CENPF | centromere protein F, 350/400kDa | 0.0255147 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.0252478 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0250752 |
| COL1A2 | collagen, type I, alpha 2 | 0.0250449 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0249982 |
| ADAR | adenosine deaminase, RNA-specific | 0.0246182 |
| TCP1 | t-complex 1 | 0.0245276 |
| NAV1 | neuron navigator 1 | 0.0244551 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0243541 |
| RPS4X | ribosomal protein S4, X-linked | 0.0243474 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0242682 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0240792 |
| CDK17 | cyclin-dependent kinase 17 | 0.0240345 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0240078 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0237314 |
| CUL4B | cullin 4B | 0.0235187 |
| SERINC1 | serine incorporator 1 | 0.0234485 |
| LOXL2 | lysyl oxidase-like 2 | 0.0234068 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0232331 |
| FNIP1 | folliculin interacting protein 1 | 0.0229999 |
| CTSB | cathepsin B | 0.0226391 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0224238 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0222808 |
| WDR1 | WD repeat domain 1 | 0.0222339 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0222336 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0219418 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0218817 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0218618 |
| VEGFA | vascular endothelial growth factor A | 0.0218265 |
| PRRC2B | proline-rich coiled-coil 2B | 0.021427 |
| FNDC3B | fibronectin type III domain containing 3B | 0.021252 |
| CKAP5 | cytoskeleton associated protein 5 | 0.021124 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0210612 |
| TRIM22 | tripartite motif containing 22 | 0.0210041 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0208075 |
| KLF12 | Kruppel-like factor 12 | 0.020792 |
| SDC4 | syndecan 4 | 0.0207846 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.114887 |
| VIM | vimentin | -0.114743 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.100601 |
| NDRG1 | N-myc downstream regulated 1 | -0.0699857 |
| RPS6 | ribosomal protein S6 | -0.0674622 |
| EGR1 | early growth response 1 | -0.0568376 |
| TMSB10 | thymosin beta 10 | -0.0532061 |
| PTMA | prothymosin, alpha | -0.0527029 |
| FTL | ferritin, light polypeptide | -0.0440783 |
| HLA-B | major histocompatibility complex, class I, B | -0.0426704 |
| RPS8 | ribosomal protein S8 | -0.0426114 |
| MT2A | metallothionein 2A | -0.0412526 |
| RPL37A | ribosomal protein L37a | -0.0410666 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0395666 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0386512 |
| ACTG1 | actin gamma 1 | -0.0348475 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0326627 |
| RPS3 | ribosomal protein S3 | -0.0325455 |
| ZNF292 | zinc finger protein 292 | -0.0325299 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0324824 |
| HMGA1 | high mobility group AT-hook 1 | -0.03224 |
| RPS12 | ribosomal protein S12 | -0.0310907 |
| RPL9 | ribosomal protein L9 | -0.0301073 |
| GNAS | GNAS complex locus | -0.0298662 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0297744 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0287829 |
| B2M | beta-2-microglobulin | -0.0287662 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.028718 |
| RPL12 | ribosomal protein L12 | -0.0279543 |
| TAPBP | TAP binding protein (tapasin) | -0.0278734 |
| RPL26 | ribosomal protein L26 | -0.0265405 |
| RPLP1 | ribosomal protein, large, P1 | -0.0255538 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0252815 |
| RPS19 | ribosomal protein S19 | -0.0251061 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0247598 |
| RPL35A | ribosomal protein L35a | -0.0245797 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0244792 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0242125 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.02378 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0237504 |
| SEPTIN7 | septin 7 | -0.0237372 |
| IER3 | immediate early response 3 | -0.0235738 |
| RACK1 | receptor for activated C kinase 1 | -0.0233114 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.022669 |
| RPL23 | ribosomal protein L23 | -0.022486 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0222033 |
| RPS24 | ribosomal protein S24 | -0.0221957 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0220063 |
| RPL19 | ribosomal protein L19 | -0.0219854 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0219099 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0218961 |
| GPC6 | glypican 6 | -0.0218201 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0216487 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | -0.0213912 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.0213844 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0208219 |
| CTSD | cathepsin D | -0.0207655 |
| CIRSR | corepressor of RBPJ and splicing regulator | -0.0205871 |
| GPBP1 | GC-rich promoter binding protein 1 | -0.0205711 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0204777 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0203852 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.02026 |
| RPS27A | ribosomal protein S27a | -0.0201105 |
| RPL36A | ribosomal protein L36a | -0.0195543 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0194385 |
| RPL5 | ribosomal protein L5 | -0.0194365 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0192545 |
| GOLGA4 | golgin A4 | -0.0189497 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0189026 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0188925 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0188678 |
| ATF4 | activating transcription factor 4 | -0.0186234 |
| COL1A1 | collagen, type I, alpha 1 | -0.0185809 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0185309 |
| RPL36 | ribosomal protein L36 | -0.018497 |
| RPL32 | ribosomal protein L32 | -0.0179831 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | -0.0178608 |
| PPIG | peptidylprolyl isomerase G (cyclophilin G) | -0.0177541 |
| S100A9 | S100 calcium binding protein A9 | -0.0176629 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.017627 |
| FAM162A | family with sequence similarity 162, member A | -0.0175303 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0174965 |
| SMAP1 | small ArfGAP 1 | -0.0173693 |
| NF1 | neurofibromin 1 | -0.0171784 |
| JMJD1C | jumonji domain containing 1C | -0.0170682 |
| MED13 | mediator complex subunit 13 | -0.0170457 |
| RPS29 | ribosomal protein S29 | -0.0168428 |
| MATR3 | matrin 3 | -0.0168231 |
| RNF24 | ring finger protein 24 | -0.0167196 |
| RPLP0 | ribosomal protein, large, P0 | -0.0165753 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.016549 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0164909 |
| STC1 | stanniocalcin 1 | -0.0163956 |
| PIAS1 | protein inhibitor of activated STAT, 1 | -0.0163587 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | -0.0162742 |
| ZMYM4 | zinc finger, MYM-type 4 | -0.0161833 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0160948 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0160853 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0160812 |
| RPS14 | ribosomal protein S14 | -0.0160468 |
