| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Arbutin perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Arbutin_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.220987 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.113481 |
| B2M | beta-2-microglobulin | 0.106161 |
| LDHA | lactate dehydrogenase A | 0.0765533 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0757661 |
| HLA-B | major histocompatibility complex, class I, B | 0.0714713 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0686411 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0677476 |
| FAM13A | family with sequence similarity 13, member A | 0.0648116 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0645908 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0634644 |
| SDC4 | syndecan 4 | 0.0602642 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0600438 |
| CANX | calnexin | 0.0581058 |
| ARRDC3 | arrestin domain containing 3 | 0.0579698 |
| HLA-A | major histocompatibility complex, class I, A | 0.0562001 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0560908 |
| WTAP | Wilms tumor 1 associated protein | 0.0525579 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0510393 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0510112 |
| ATP13A3 | ATPase type 13A3 | 0.0498615 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0474558 |
| FTL | ferritin, light polypeptide | 0.0454487 |
| CD109 | CD109 molecule | 0.0446882 |
| UBC | ubiquitin C | 0.0438794 |
| XBP1 | X-box binding protein 1 | 0.0415043 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0400318 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0394044 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0387367 |
| HELZ | helicase with zinc finger | 0.0386501 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0371645 |
| ANXA1 | annexin A1 | 0.0368972 |
| INSIG2 | insulin induced gene 2 | 0.0362681 |
| YTHDC1 | YTH domain containing 1 | 0.0361358 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.0354179 |
| NDRG1 | N-myc downstream regulated 1 | 0.035356 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.03532 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0353061 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0352311 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | 0.0349483 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0346722 |
| IL6 | interleukin 6 | 0.0340821 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.034072 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0338835 |
| IRF1 | interferon regulatory factor 1 | 0.0338408 |
| SPAG9 | sperm associated antigen 9 | 0.0334518 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0334428 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0331053 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.032828 |
| QKI | QKI, KH domain containing, RNA binding | 0.0326603 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0320646 |
| GOLGA4 | golgin A4 | 0.0320024 |
| YEATS2 | YEATS domain containing 2 | 0.03174 |
| TXNIP | thioredoxin interacting protein | 0.0313008 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0307215 |
| ZNF292 | zinc finger protein 292 | 0.0306608 |
| MATR3 | matrin 3 | 0.0302149 |
| SFTPA2 | surfactant protein A2 | 0.0301989 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0292289 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0290995 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0282384 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0281196 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0277526 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0277186 |
| PCBP2 | poly(rC) binding protein 2 | 0.0276391 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0274114 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0274076 |
| XPO1 | exportin 1 | 0.0267706 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0262019 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0259067 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0256557 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0256503 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0253058 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0252726 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0250195 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0247752 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0247635 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0247183 |
| TPM4 | tropomyosin 4 | 0.0241954 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0240928 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0240205 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | 0.0239018 |
| RTN4 | reticulon 4 | 0.0238749 |
| TSC22D2 | TSC22 domain family, member 2 | 0.023731 |
| USP3 | ubiquitin specific peptidase 3 | 0.0236649 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0234431 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.0234089 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0234014 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0233785 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0233718 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.0233621 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0231004 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.02305 |
| FOXN2 | forkhead box N2 | 0.0230474 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | 0.0230207 |
| ITM2B | integral membrane protein 2B | 0.0227183 |
| RPS3 | ribosomal protein S3 | 0.022472 |
| KDM1A | lysine (K)-specific demethylase 1A | 0.0224405 |
| WASF2 | WAS protein family, member 2 | 0.0223984 |
| MTMR4 | myotubularin related protein 4 | 0.022389 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.248524 |
| FN1 | fibronectin 1 | -0.0973235 |
| CDH13 | cadherin 13 | -0.09568 |
| LOX | lysyl oxidase | -0.0902496 |
| HMGA2 | high mobility group AT-hook 2 | -0.0700326 |
| NRXN3 | neurexin 3 | -0.0660207 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0650499 |
| EGFR | epidermal growth factor receptor | -0.0640606 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0629577 |
| CALD1 | caldesmon 1 | -0.0618961 |
| GLIS3 | GLIS family zinc finger 3 | -0.0589233 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0560913 |
| TMSB10 | thymosin beta 10 | -0.0546727 |
| CDK6 | cyclin-dependent kinase 6 | -0.0535862 |
| VCL | vinculin | -0.0514215 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0499522 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0477525 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0468193 |
| HIPK2 | homeodomain interacting protein kinase 2 | -0.0457982 |
| STC1 | stanniocalcin 1 | -0.0452411 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0420491 |
| COL1A1 | collagen, type I, alpha 1 | -0.0410797 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0403367 |
| FRMD4A | FERM domain containing 4A | -0.0400701 |
| MYOF | myoferlin | -0.0400372 |
| CD44 | CD44 molecule (Indian blood group) | -0.039915 |
| TNS3 | tensin 3 | -0.0397356 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0386847 |
| PRKCA | protein kinase C, alpha | -0.0385575 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0384393 |
| RAD51B | RAD51 paralog B | -0.0374371 |
| NABP1 | nucleic acid binding protein 1 | -0.0367946 |
| DST | dystonin | -0.0367326 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0356713 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0340581 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0339516 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.033875 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0336977 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0335103 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0323254 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0322451 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.0322085 |
| COL1A2 | collagen, type I, alpha 2 | -0.0312845 |
| EXOC4 | exocyst complex component 4 | -0.0298781 |
| VEGFC | vascular endothelial growth factor C | -0.029351 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0287806 |
| ACTG1 | actin gamma 1 | -0.0284274 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0281829 |
| RUNX1 | runt-related transcription factor 1 | -0.0280519 |
| HDAC9 | histone deacetylase 9 | -0.0278661 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.027787 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0277393 |
| JPH2 | junctophilin 2 | -0.0274396 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.026824 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | -0.0267145 |
| MYO1E | myosin IE | -0.0263739 |
| CLASP1 | cytoplasmic linker associated protein 1 | -0.0262823 |
| RAB31 | RAB31, member RAS oncogene family | -0.0261112 |
| POTEF | POTE ankyrin domain family, member F | -0.0261108 |
| BPTF | bromodomain PHD finger transcription factor | -0.0259811 |
| MAP4 | microtubule-associated protein 4 | -0.0259394 |
| EGR1 | early growth response 1 | -0.0255343 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.0253932 |
| VIM | vimentin | -0.0252718 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0252718 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -0.0252131 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0249611 |
| FER | fer (fps/fes related) tyrosine kinase | -0.0246783 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0246469 |
| INTS6 | integrator complex subunit 6 | -0.0245066 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | -0.0244777 |
| ITGAV | integrin, alpha V | -0.0244572 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0242419 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0241194 |
| OSBPL8 | oxysterol binding protein-like 8 | -0.0240822 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0240795 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0236442 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0234559 |
| RCOR1 | REST corepressor 1 | -0.0232375 |
| HM13 | histocompatibility (minor) 13 | -0.0231987 |
| RBPMS | RNA binding protein with multiple splicing | -0.0231863 |
| SETX | senataxin | -0.023166 |
| PRELID2 | PRELI domain containing 2 | -0.0231271 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) | -0.0228899 |
| ABLIM3 | actin binding LIM protein family, member 3 | -0.022536 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0224321 |
| MT2A | metallothionein 2A | -0.0222706 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0221997 |
| TENM3 | teneurin transmembrane protein 3 | -0.0221541 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0220827 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0216166 |
| MPRIP | myosin phosphatase Rho interacting protein | -0.0215938 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0215192 |
| DMTF1 | cyclin D binding myb-like transcription factor 1 | -0.0212947 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0212323 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 | -0.0212302 |
| CLIC4 | chloride intracellular channel 4 | -0.0209346 |
| SYNPO | synaptopodin | -0.0207919 |
| MYSM1 | Myb-like, SWIRM and MPN domains 1 | -0.0207881 |
| ASPH | aspartate beta-hydroxylase | -0.020758 |
