| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Arbutin perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Arbutin_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LDHA | lactate dehydrogenase A | 0.206529 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0986985 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0793285 |
| CANX | calnexin | 0.0723716 |
| CEP250 | centrosomal protein 250kDa | 0.0697686 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0687316 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0673094 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0667671 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.065288 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.062659 |
| RBM39 | RNA binding motif protein 39 | 0.0622338 |
| CPNE1 | copine I | 0.0603443 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.058622 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0560647 |
| OSMR | oncostatin M receptor | 0.0556689 |
| FLNB | filamin B, beta | 0.0545897 |
| RPL3 | ribosomal protein L3 | 0.0523983 |
| CENPF | centromere protein F, 350/400kDa | 0.0518896 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0513083 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0510449 |
| TPX2 | TPX2, microtubule-associated | 0.0509414 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0500428 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0499594 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0485876 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0451816 |
| FMNL2 | formin-like 2 | 0.0445305 |
| SMAD3 | SMAD family member 3 | 0.0439131 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0431669 |
| TPM3 | tropomyosin 3 | 0.0418498 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0416073 |
| SPAG9 | sperm associated antigen 9 | 0.0414614 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0409624 |
| FLNA | filamin A, alpha | 0.038646 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0382542 |
| MCL1 | myeloid cell leukemia 1 | 0.0377855 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0377386 |
| AHNAK | AHNAK nucleoprotein | 0.037556 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0375129 |
| AARS1 | alanyl-tRNA synthetase 1 | 0.0370487 |
| ANXA2 | annexin A2 | 0.0361992 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0359444 |
| SS18 | synovial sarcoma translocation, chromosome 18 | 0.0359089 |
| GOLGA3 | golgin A3 | 0.0355601 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0348966 |
| SET | SET nuclear proto-oncogene | 0.0346296 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0340948 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0336146 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0335579 |
| TPM4 | tropomyosin 4 | 0.0335037 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0324602 |
| PYGL | phosphorylase, glycogen, liver | 0.0322828 |
| RPL11 | ribosomal protein L11 | 0.0321487 |
| INCENP | inner centromere protein antigens 135/155kDa | 0.0320012 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | 0.0316933 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0313971 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0313376 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0312312 |
| ZNF292 | zinc finger protein 292 | 0.031072 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0310701 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0310025 |
| SETD5 | SET domain containing 5 | 0.0309758 |
| APP | amyloid beta (A4) precursor protein | 0.0309511 |
| CAPRIN2 | caprin family member 2 | 0.0308686 |
| SAFB | scaffold attachment factor B | 0.0307826 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0304732 |
| TGM2 | transglutaminase 2 | 0.0304606 |
| NUP58 | nucleoporin 58 | 0.0303163 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0301724 |
| G3BP2 | GTPase activating protein (SH3 domain) binding protein 2 | 0.0300184 |
| PIKFYVE | phosphoinositide kinase, FYVE finger containing | 0.0300053 |
| HJURP | Holliday junction recognition protein | 0.0299528 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0299293 |
| CTTN | cortactin | 0.0298579 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0296706 |
| MRE11 | MRE11 homolog, double strand break repair nuclease | 0.0296706 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.029588 |
| PANK3 | pantothenate kinase 3 | 0.0294575 |
| PCBP2 | poly(rC) binding protein 2 | 0.029454 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.029437 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0293716 |
| ACTN1 | actinin, alpha 1 | 0.02917 |
| CDK5RAP2 | CDK5 regulatory subunit associated protein 2 | 0.0291237 |
| RPL12 | ribosomal protein L12 | 0.0287578 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0287516 |
| NRBP1 | nuclear receptor binding protein 1 | 0.0286743 |
| TXNRD1 | thioredoxin reductase 1 | 0.0286595 |
| RAB10 | RAB10, member RAS oncogene family | 0.0286043 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0285534 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0285411 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 | 0.0284529 |
| CHD3 | chromodomain helicase DNA binding protein 3 | 0.028446 |
| CALR | calreticulin | 0.0283649 |
| RAB6A | RAB6A, member RAS oncogene family | 0.028197 |
| RPL4 | ribosomal protein L4 | 0.0281719 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0279961 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0279496 |
| CLTC | clathrin, heavy chain (Hc) | 0.0276574 |
| PLEC | plectin | 0.0275559 |
| RANBP2 | RAN binding protein 2 | 0.0268772 |
| CCDC47 | coiled-coil domain containing 47 | 0.0267814 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.2816 |
| TMSB10 | thymosin beta 10 | -0.0739971 |
| VIM | vimentin | -0.070517 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.062696 |
| CD44 | CD44 molecule (Indian blood group) | -0.0613942 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0587646 |
| HMGA2 | high mobility group AT-hook 2 | -0.0467239 |
| MT2A | metallothionein 2A | -0.0374161 |
| IER3 | immediate early response 3 | -0.0371179 |
| POTEF | POTE ankyrin domain family, member F | -0.0355182 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0355033 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0348867 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0342504 |
| H3-3B | H3.3 histone B | -0.0334642 |
| RIGI | RNA sensor RIG-I | -0.0333924 |
| PFN1 | profilin 1 | -0.0325428 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0318178 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0312987 |
| RACK1 | receptor for activated C kinase 1 | -0.0312137 |
| EGR1 | early growth response 1 | -0.0304485 |
| RPS21 | ribosomal protein S21 | -0.0297971 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0290821 |
| ATF7IP | activating transcription factor 7 interacting protein | -0.0286302 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0284499 |
| RHEB | Ras homolog enriched in brain | -0.0283133 |
| HLA-B | major histocompatibility complex, class I, B | -0.0274895 |
| GPATCH2L | G patch domain containing 2-like | -0.027415 |
| S100A10 | S100 calcium binding protein A10 | -0.0273496 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0263022 |
| NALCN | sodium leak channel, non selective | -0.0261301 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0260906 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0249952 |
| RPL27A | ribosomal protein L27a | -0.0247669 |
| SLMAP | sarcolemma associated protein | -0.0241606 |
| RPS25 | ribosomal protein S25 | -0.0241266 |
| SVIL | supervillin | -0.0239973 |
| HBS1L | HBS1-like translational GTPase | -0.0239257 |
| S100A6 | S100 calcium binding protein A6 | -0.0238184 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0236843 |
| S100A9 | S100 calcium binding protein A9 | -0.0233199 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0231337 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0230636 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0230044 |
| RPLP1 | ribosomal protein, large, P1 | -0.022776 |
| RPL35A | ribosomal protein L35a | -0.0227099 |
| DENND5B | DENN/MADD domain containing 5B | -0.0223679 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.0222587 |
| RPS6 | ribosomal protein S6 | -0.0221356 |
| FTL | ferritin, light polypeptide | -0.0220279 |
| HDAC9 | histone deacetylase 9 | -0.0218128 |
| SNX14 | sorting nexin 14 | -0.0217854 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0217163 |
| CDK6 | cyclin-dependent kinase 6 | -0.0214983 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | -0.0210994 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0210756 |
| CEBPZ | CCAAT/enhancer binding protein (C/EBP), zeta | -0.0209561 |
| RPS8 | ribosomal protein S8 | -0.0209431 |
| RPL36A | ribosomal protein L36a | -0.0208295 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | -0.0206972 |
| CENPP | centromere protein P | -0.0203653 |
| JMJD1C | jumonji domain containing 1C | -0.0203263 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | -0.0202747 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0202177 |
| WBP11 | WW domain binding protein 11 | -0.0198313 |
| ARL15 | ADP-ribosylation factor-like 15 | -0.0197538 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0196782 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0196079 |
| RPS13 | ribosomal protein S13 | -0.0191386 |
| PURA | purine-rich element binding protein A | -0.0191341 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.019096 |
| RPS3 | ribosomal protein S3 | -0.0189213 |
| ARL8B | ADP-ribosylation factor-like 8B | -0.0188869 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0187554 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0187274 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0186974 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0184524 |
| WASHC4 | WASH complex subunit 4 | -0.0183646 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0183531 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | -0.0182864 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0182686 |
| SBF2 | SET binding factor 2 | -0.018266 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0181773 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0181621 |
| KLF6 | Kruppel-like factor 6 | -0.0181052 |
| B2M | beta-2-microglobulin | -0.0181026 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.018096 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0180478 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0179481 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0179447 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0177756 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0177731 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0176934 |
| SCAMP1 | secretory carrier membrane protein 1 | -0.0176168 |
| CCDC50 | coiled-coil domain containing 50 | -0.0175426 |
| CBX3 | chromobox homolog 3 | -0.0174404 |
| CD164 | CD164 molecule, sialomucin | -0.0173911 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0173571 |
| ATG12 | autophagy related 12 | -0.0172993 |
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 | -0.017042 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.0168888 |
