| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Arbutin perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Arbutin_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.116144 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0876429 |
| CANX | calnexin | 0.0855791 |
| VEGFA | vascular endothelial growth factor A | 0.0840929 |
| FLNA | filamin A, alpha | 0.0729023 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0695436 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.06823 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0665606 |
| CENPF | centromere protein F, 350/400kDa | 0.0629559 |
| RPL3 | ribosomal protein L3 | 0.0573875 |
| GLUL | glutamate-ammonia ligase | 0.0565472 |
| MKI67 | marker of proliferation Ki-67 | 0.0550494 |
| SFTPA2 | surfactant protein A2 | 0.0545551 |
| ASPH | aspartate beta-hydroxylase | 0.0525909 |
| SMAD3 | SMAD family member 3 | 0.0513414 |
| RPL13A | ribosomal protein L13a | 0.0506581 |
| APP | amyloid beta (A4) precursor protein | 0.0503098 |
| FN1 | fibronectin 1 | 0.0500306 |
| SMOX | spermine oxidase | 0.0493218 |
| LDHA | lactate dehydrogenase A | 0.0467809 |
| HDGF | hepatoma-derived growth factor | 0.0464035 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0458696 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0455706 |
| PELO | pelota homolog (Drosophila) | 0.0448797 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0443772 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0436812 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0422118 |
| MCL1 | myeloid cell leukemia 1 | 0.0420977 |
| HMGA2 | high mobility group AT-hook 2 | 0.0400576 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0398659 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0395539 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0388225 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0387724 |
| CALR | calreticulin | 0.0382653 |
| HMGB3 | high mobility group box 3 | 0.0368847 |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase | 0.0367266 |
| NDRG1 | N-myc downstream regulated 1 | 0.0365154 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0363366 |
| PLEC | plectin | 0.0361403 |
| PRELID2 | PRELI domain containing 2 | 0.0358714 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0353984 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0344849 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0343922 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0338844 |
| HDLBP | high density lipoprotein binding protein | 0.0336636 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0332493 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0331195 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0323217 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0322927 |
| STC2 | stanniocalcin 2 | 0.0319073 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0311754 |
| QSOX1 | quiescin Q6 sulfhydryl oxidase 1 | 0.0311045 |
| CEP250 | centrosomal protein 250kDa | 0.0311022 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0307914 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0304325 |
| ACTN1 | actinin, alpha 1 | 0.0298381 |
| FAM20C | family with sequence similarity 20, member C | 0.0297939 |
| ADAR | adenosine deaminase, RNA-specific | 0.0295662 |
| LOXL2 | lysyl oxidase-like 2 | 0.0292404 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0291407 |
| AHNAK | AHNAK nucleoprotein | 0.0290076 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0284607 |
| TMSB4X | thymosin beta 4, X-linked | 0.027689 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0276154 |
| RPL18A | ribosomal protein L18a | 0.0266436 |
| PLIN2 | perilipin 2 | 0.0264739 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0263107 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0261985 |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 | 0.0258502 |
| OGA | O-GlcNAcase | 0.0254936 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.0253953 |
| GOLPH3 | golgi phosphoprotein 3 (coat-protein) | 0.0253652 |
| ACIN1 | apoptotic chromatin condensation inducer 1 | 0.0252803 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0243946 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.024321 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0242165 |
| TSPYL2 | TSPY-like 2 | 0.0240773 |
| TPM3 | tropomyosin 3 | 0.0239005 |
| GNAS | GNAS complex locus | 0.0237917 |
| HNRNPUL1 | heterogeneous nuclear ribonucleoprotein U-like 1 | 0.0234733 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0233963 |
| CNOT6 | CCR4-NOT transcription complex, subunit 6 | 0.0233776 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0233396 |
| TOP1 | topoisomerase (DNA) I | 0.0232868 |
| RPL11 | ribosomal protein L11 | 0.023279 |
| COPA | coatomer protein complex, subunit alpha | 0.0232742 |
| GLIS3 | GLIS family zinc finger 3 | 0.023003 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0229374 |
| TNS3 | tensin 3 | 0.0227905 |
| DDX41 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 | 0.0227338 |
| SEC24C | SEC24 family member C | 0.0222775 |
| PRKCSH | protein kinase C substrate 80K-H | 0.0221998 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0220884 |
| ARHGAP35 | Rho GTPase activating protein 35 | 0.0220617 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0218845 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0215707 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0215342 |
| NPTN | neuroplastin | 0.021483 |
| RPH3AL | rabphilin 3A-like (without C2 domains) | 0.0213361 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.02133 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.324609 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.139909 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.138561 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0367357 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0357718 |
| IER3 | immediate early response 3 | -0.0295782 |
| RPS24 | ribosomal protein S24 | -0.0292829 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.029202 |
| EREG | epiregulin | -0.0286959 |
| MT2A | metallothionein 2A | -0.026157 |
| HMGA1 | high mobility group AT-hook 1 | -0.0261525 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0260694 |
| RPS25 | ribosomal protein S25 | -0.0259379 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0255213 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.0251936 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0249754 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0247011 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0242961 |
| FTL | ferritin, light polypeptide | -0.0242271 |
| SYT1 | synaptotagmin I | -0.0241435 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0229914 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0225336 |
| VMP1 | vacuole membrane protein 1 | -0.0224845 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0224209 |
| VIM | vimentin | -0.0222902 |
| RPS16 | ribosomal protein S16 | -0.0221168 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0217533 |
| NRG1 | neuregulin 1 | -0.0216926 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0212466 |
| TMEM156 | transmembrane protein 156 | -0.0210837 |
| RTN4 | reticulon 4 | -0.0209335 |
| GPBP1 | GC-rich promoter binding protein 1 | -0.0208483 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0205253 |
| WASF2 | WAS protein family, member 2 | -0.0204276 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.02031 |
| IL6ST | interleukin 6 signal transducer | -0.0202753 |
| TRAM1 | translocation associated membrane protein 1 | -0.0201753 |
| ETNK1 | ethanolamine kinase 1 | -0.0201002 |
| RPS23 | ribosomal protein S23 | -0.0200834 |
| PPP1R15B | protein phosphatase 1, regulatory subunit 15B | -0.0195711 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0194126 |
| GPHN | gephyrin | -0.0193789 |
| RYBP | RING1 and YY1 binding protein | -0.0192904 |
| RPLP0 | ribosomal protein, large, P0 | -0.0191097 |
| NOP58 | NOP58 ribonucleoprotein | -0.0189289 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0188858 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.0186372 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0186316 |
| RHEB | Ras homolog enriched in brain | -0.01859 |
| EGR1 | early growth response 1 | -0.0185211 |
| RPL35A | ribosomal protein L35a | -0.0184576 |
| FRMD5 | FERM domain containing 5 | -0.0182846 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0179704 |
| ETV1 | ets variant 1 | -0.017934 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0178428 |
| MTDH | metadherin | -0.0178291 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0170914 |
| KLHL5 | kelch-like family member 5 | -0.0170297 |
| IDS | iduronate 2-sulfatase | -0.0166378 |
| S100A10 | S100 calcium binding protein A10 | -0.0165336 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.016486 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0163058 |
| ASTN2 | astrotactin 2 | -0.0162644 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0162573 |
| PIM3 | Pim-3 proto-oncogene, serine/threonine kinase | -0.0162071 |
| UBAP1 | ubiquitin associated protein 1 | -0.0162036 |
| RPS6 | ribosomal protein S6 | -0.0161377 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0160773 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | -0.0158907 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0158078 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0157753 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0157279 |
| RPS29 | ribosomal protein S29 | -0.015685 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0156848 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0156159 |
| USP15 | ubiquitin specific peptidase 15 | -0.0155024 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0154842 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0154004 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.015329 |
| RPL31 | ribosomal protein L31 | -0.0152756 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0152001 |
| RLF | rearranged L-myc fusion | -0.0151806 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0151503 |
| CDK12 | cyclin-dependent kinase 12 | -0.0150691 |
| ATP13A3 | ATPase type 13A3 | -0.0150031 |
| CDK17 | cyclin-dependent kinase 17 | -0.014851 |
| NTN4 | netrin 4 | -0.0148162 |
| JMJD1C | jumonji domain containing 1C | -0.0147218 |
| REL | v-rel avian reticuloendotheliosis viral oncogene homolog | -0.0145988 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.0145638 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0145282 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0144298 |
| UBE2R2 | ubiquitin-conjugating enzyme E2R 2 | -0.0143568 |
| LOX | lysyl oxidase | -0.0142199 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0142192 |
| RAB10 | RAB10, member RAS oncogene family | -0.0140318 |
| COG5 | component of oligomeric golgi complex 5 | -0.0139991 |
| DENND4C | DENN/MADD domain containing 4C | -0.0139747 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0139581 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | -0.0138833 |
