Arecoline Gene Set

Dataset CTD Gene-Chemical Interactions
Category physical interactions
Type chemical
Description A tetrahydropyridine that is 1,2,5,6-tetrahydropyridine with a methyl group at position 1, and a methoxycarbonyl group at position 3. An alkaloid found in the areca nut, it acts as an agonist of muscarinic acetylcholine. (Chemical Entities of Biological Interest Ontology, CHEBI_2814)
External Link http://ctdbase.org/detail.go?type=chem&acc=D001115
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Genes

22 genes/proteins interacting with the chemical Arecoline from the curated CTD Gene-Chemical Interactions dataset.

Symbol Name
AR androgen receptor
BCL2 B-cell CLL/lymphoma 2
CASP3 caspase 3, apoptosis-related cysteine peptidase
CCL5 chemokine (C-C motif) ligand 5
CCND1 cyclin D1
CDC25C cell division cycle 25C
CDK1 cyclin-dependent kinase 1
CDK4 cyclin-dependent kinase 4
CHRM3 cholinergic receptor, muscarinic 3
CRYAB crystallin, alpha B
CXCL8 chemokine (C-X-C motif) ligand 8
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
FSHB follicle stimulating hormone, beta polypeptide
HSPB1 heat shock 27kDa protein 1
IL6 interleukin 6
LHB luteinizing hormone beta polypeptide
MMP2 matrix metallopeptidase 2
MYOG myogenin (myogenic factor 4)
TIMP1 TIMP metallopeptidase inhibitor 1
TP53 tumor protein p53