| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Artemether perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Artemether_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TRIO | trio Rho guanine nucleotide exchange factor | 0.103418 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.100129 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.08945 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0718145 |
| FBN1 | fibrillin 1 | 0.0657978 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0620728 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0577636 |
| FNDC3B | fibronectin type III domain containing 3B | 0.056219 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0472892 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.047155 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0469227 |
| LOX | lysyl oxidase | 0.0466168 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0465867 |
| DST | dystonin | 0.0409844 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0390848 |
| ATP13A3 | ATPase type 13A3 | 0.0390737 |
| APP | amyloid beta (A4) precursor protein | 0.0378691 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0375942 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0350616 |
| UBC | ubiquitin C | 0.0349183 |
| MSN | moesin | 0.0341206 |
| SQSTM1 | sequestosome 1 | 0.0337519 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0331446 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0313863 |
| CANX | calnexin | 0.0302883 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.030137 |
| CD109 | CD109 molecule | 0.0299874 |
| RUNX1 | runt-related transcription factor 1 | 0.0298919 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0293152 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0289366 |
| FNIP1 | folliculin interacting protein 1 | 0.0287891 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0287378 |
| GOLGA4 | golgin A4 | 0.0287005 |
| COPA | coatomer protein complex, subunit alpha | 0.0285108 |
| AUTS2 | autism susceptibility candidate 2 | 0.0274652 |
| C1D | C1D nuclear receptor corepressor | 0.0274176 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0273528 |
| INSIG2 | insulin induced gene 2 | 0.0265267 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0265052 |
| HELZ | helicase with zinc finger | 0.0260226 |
| SUCO | SUN domain containing ossification factor | 0.0259582 |
| COL5A2 | collagen, type V, alpha 2 | 0.0253784 |
| OGA | O-GlcNAcase | 0.0253299 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0253012 |
| OPTN | optineurin | 0.0251443 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0248471 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0246393 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0245321 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0244721 |
| NT5C2 | 5'-nucleotidase, cytosolic II | 0.024366 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0238783 |
| SBF2 | SET binding factor 2 | 0.0238381 |
| MXI1 | MAX interactor 1, dimerization protein | 0.023714 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.023677 |
| ANO6 | anoctamin 6 | 0.0236395 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0231969 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0230194 |
| MMP12 | matrix metallopeptidase 12 | 0.0229084 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0225925 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0219578 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0219256 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0213797 |
| NAV2 | neuron navigator 2 | 0.0211892 |
| GPC6 | glypican 6 | 0.0210443 |
| NGLY1 | N-glycanase 1 | 0.0207323 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0204891 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.020476 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0204168 |
| MYOF | myoferlin | 0.0203876 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0200202 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0199522 |
| RNF145 | ring finger protein 145 | 0.0199375 |
| ARRDC3 | arrestin domain containing 3 | 0.0196601 |
| WDFY1 | WD repeat and FYVE domain containing 1 | 0.0196117 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0195967 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0195751 |
| FLNB | filamin B, beta | 0.0192348 |
| THBS2 | thrombospondin 2 | 0.0191315 |
| NOTCH2 | notch 2 | 0.0190516 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0189431 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0189277 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0189049 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.0188997 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0188722 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0188462 |
| ATP2C1 | ATPase, Ca++ transporting, type 2C, member 1 | 0.0187408 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | 0.018714 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0186913 |
| COG5 | component of oligomeric golgi complex 5 | 0.0186747 |
| AFDN | afadin, adherens junction formation factor | 0.0186518 |
| LDHA | lactate dehydrogenase A | 0.0184512 |
| RAB18 | RAB18, member RAS oncogene family | 0.0182382 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0180898 |
| MIMS1 | mitochondrial inner membrane scaffold 1 | 0.0180376 |
| LPCAT2 | lysophosphatidylcholine acyltransferase 2 | 0.018008 |
| FAM107B | family with sequence similarity 107, member B | 0.0179935 |
| XPO1 | exportin 1 | 0.0178563 |
| NCKAP1 | NCK-associated protein 1 | 0.0177642 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0177592 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0174262 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.296603 |
| MT2A | metallothionein 2A | -0.204092 |
| VIM | vimentin | -0.203305 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.199838 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.134549 |
| S100A10 | S100 calcium binding protein A10 | -0.0961057 |
| HLA-B | major histocompatibility complex, class I, B | -0.0901165 |
| PLAT | plasminogen activator, tissue | -0.0747168 |
| LMNA | lamin A/C | -0.0705398 |
| S100A6 | S100 calcium binding protein A6 | -0.0690615 |
| CSTB | cystatin B (stefin B) | -0.0674926 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0625581 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0503865 |
| MT1X | metallothionein 1X | -0.0502781 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0479473 |
| FN1 | fibronectin 1 | -0.0463384 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0463158 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0453388 |
| HLA-C | major histocompatibility complex, class I, C | -0.0446156 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0437518 |
| B2M | beta-2-microglobulin | -0.0435242 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0433769 |
| RPL35A | ribosomal protein L35a | -0.042272 |
| NAV1 | neuron navigator 1 | -0.0422166 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.0420224 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0403097 |
| MAP1B | microtubule-associated protein 1B | -0.0399794 |
| FTL | ferritin, light polypeptide | -0.0392183 |
| RPS19 | ribosomal protein S19 | -0.0381148 |
| RPL23 | ribosomal protein L23 | -0.0381117 |
| RPLP2 | ribosomal protein, large, P2 | -0.0370889 |
| SUCNR1 | succinate receptor 1 | -0.0363391 |
| RPLP1 | ribosomal protein, large, P1 | -0.0356399 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0350822 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0349571 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0349565 |
| RPL28 | ribosomal protein L28 | -0.0347067 |
| PRSS23 | protease, serine, 23 | -0.0346257 |
| TAGLN2 | transgelin 2 | -0.0346068 |
| MX2 | MX dynamin-like GTPase 2 | -0.0340016 |
| PKM | pyruvate kinase, muscle | -0.0335613 |
| SEC61G | Sec61 gamma subunit | -0.0334463 |
| S100A4 | S100 calcium binding protein A4 | -0.033214 |
| RPS8 | ribosomal protein S8 | -0.0328236 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0325734 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0322497 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0322464 |
| S100A11 | S100 calcium binding protein A11 | -0.0319789 |
| CD99 | CD99 molecule | -0.0316886 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0315158 |
| RPL36 | ribosomal protein L36 | -0.0309753 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0306695 |
| RPL37A | ribosomal protein L37a | -0.0305066 |
| RRBP1 | ribosome binding protein 1 | -0.0302353 |
| HSPB1 | heat shock 27kDa protein 1 | -0.030146 |
| RPS6 | ribosomal protein S6 | -0.0294524 |
| CAVIN1 | caveolae associated protein 1 | -0.0293632 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0292127 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0284477 |
| CDH13 | cadherin 13 | -0.0283789 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0280555 |
| PFN1 | profilin 1 | -0.0277366 |
| RPS15 | ribosomal protein S15 | -0.0277107 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0273035 |
| RPL34 | ribosomal protein L34 | -0.027274 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0268683 |
| CKAP4 | cytoskeleton-associated protein 4 | -0.0264397 |
| PTMA | prothymosin, alpha | -0.0263954 |
| SEPTIN7 | septin 7 | -0.0262168 |
| TPM4 | tropomyosin 4 | -0.0257465 |
| RPS24 | ribosomal protein S24 | -0.0256923 |
| RPL12 | ribosomal protein L12 | -0.0256234 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0255703 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0252634 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0250693 |
| S100A9 | S100 calcium binding protein A9 | -0.0248295 |
| RPL35 | ribosomal protein L35 | -0.0247957 |
| RPL26 | ribosomal protein L26 | -0.0244883 |
| RPL32 | ribosomal protein L32 | -0.0236886 |
| RPS21 | ribosomal protein S21 | -0.0230403 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0228928 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0228439 |
| COX4I1 | cytochrome c oxidase subunit IV isoform 1 | -0.0226092 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.022317 |
| RPL31 | ribosomal protein L31 | -0.0220733 |
| RPS11 | ribosomal protein S11 | -0.0216218 |
| RNF213 | ring finger protein 213 | -0.0215388 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0214918 |
| H3-3B | H3.3 histone B | -0.0212305 |
| RPL19 | ribosomal protein L19 | -0.021075 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0209483 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0208941 |
| GNB4 | guanine nucleotide binding protein (G protein), beta polypeptide 4 | -0.0208899 |
| ACTG1 | actin gamma 1 | -0.0208785 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0206039 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 | -0.0204706 |
| LRRC17 | leucine rich repeat containing 17 | -0.0202159 |
| RPS14 | ribosomal protein S14 | -0.0201653 |
| NDRG1 | N-myc downstream regulated 1 | -0.0197712 |
| RPS13 | ribosomal protein S13 | -0.0197501 |
