| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Artemether perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Artemether_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0628732 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0617431 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0590569 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0582609 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0456465 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0455446 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0438117 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0412436 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 | 0.0358273 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0344242 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0342736 |
| ANXA1 | annexin A1 | 0.0339796 |
| MATR3 | matrin 3 | 0.0333639 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.031174 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0307723 |
| NEK7 | NIMA-related kinase 7 | 0.0306801 |
| DST | dystonin | 0.029968 |
| MED13L | mediator complex subunit 13-like | 0.0296259 |
| AHNAK | AHNAK nucleoprotein | 0.0295726 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0293394 |
| KIF5B | kinesin family member 5B | 0.0290628 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0286393 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0285174 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0277243 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0270152 |
| XPO1 | exportin 1 | 0.0269659 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0266923 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.0263522 |
| OGA | O-GlcNAcase | 0.0261499 |
| CXADR | coxsackie virus and adenovirus receptor | 0.0260524 |
| ECT2 | epithelial cell transforming 2 | 0.0253589 |
| CANX | calnexin | 0.0250529 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0246471 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0244122 |
| TXNRD1 | thioredoxin reductase 1 | 0.024355 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0239814 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0237241 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0232161 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0232092 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0231218 |
| GASK1B | golgi associated kinase 1B | 0.022944 |
| PLK2 | polo-like kinase 2 | 0.0221754 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0220149 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0216729 |
| SMYD3 | SET and MYND domain containing 3 | 0.0216076 |
| NEBL | nebulette | 0.0215843 |
| CAMKMT | calmodulin-lysine N-methyltransferase | 0.0212746 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0212232 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0211581 |
| DSPP | dentin sialophosphoprotein | 0.021148 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | 0.0209025 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0208529 |
| CCDC47 | coiled-coil domain containing 47 | 0.020784 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0206247 |
| EPHA6 | EPH receptor A6 | 0.0205927 |
| SPAG9 | sperm associated antigen 9 | 0.0205675 |
| RLF | rearranged L-myc fusion | 0.0204917 |
| LARS1 | leucyl-tRNA synthetase 1 | 0.0204389 |
| TPR | translocated promoter region, nuclear basket protein | 0.0204088 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0202607 |
| DHX36 | DEAH (Asp-Glu-Ala-His) box polypeptide 36 | 0.0201918 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0198518 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0197778 |
| CEP95 | centrosomal protein 95kDa | 0.0195752 |
| TENM3 | teneurin transmembrane protein 3 | 0.0194245 |
| APP | amyloid beta (A4) precursor protein | 0.0193555 |
| MEMO1 | mediator of cell motility 1 | 0.0192947 |
| NCKAP1 | NCK-associated protein 1 | 0.0192503 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.019182 |
| H1-0 | H1.0 linker histone | 0.0191166 |
| ZNF292 | zinc finger protein 292 | 0.0191048 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0190056 |
| TNPO1 | transportin 1 | 0.0189481 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0189227 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.0188159 |
| LMO7 | LIM domain 7 | 0.0187399 |
| SQSTM1 | sequestosome 1 | 0.0187135 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.0185306 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0184994 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0184789 |
| PRKCI | protein kinase C, iota | 0.0184312 |
| PHF3 | PHD finger protein 3 | 0.0183023 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | 0.0181703 |
| NARS1 | asparaginyl-tRNA synthetase 1 | 0.0181287 |
| AFDN | afadin, adherens junction formation factor | 0.0179682 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0179206 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0177523 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0177453 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0175505 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0175134 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0174542 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0172869 |
| ARRDC3 | arrestin domain containing 3 | 0.0172681 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0172518 |
| THOC1 | THO complex 1 | 0.0171939 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0171441 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0170729 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0169663 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0168477 |
| USP34 | ubiquitin specific peptidase 34 | 0.0166838 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.291439 |
| VIM | vimentin | -0.185044 |
| TMSB10 | thymosin beta 10 | -0.176803 |
| AREG | amphiregulin | -0.1428 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.133785 |
| NLGN1 | neuroligin 1 | -0.12201 |
| FTL | ferritin, light polypeptide | -0.0919397 |
| ACTG1 | actin gamma 1 | -0.079289 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0780663 |
| PFN1 | profilin 1 | -0.0662353 |
| HMGA1 | high mobility group AT-hook 1 | -0.0621863 |
| EGR1 | early growth response 1 | -0.0614926 |
| RPL35A | ribosomal protein L35a | -0.0570163 |
| TUBA1B | tubulin, alpha 1b | -0.0567826 |
| HMGA2 | high mobility group AT-hook 2 | -0.0563981 |
| POTEF | POTE ankyrin domain family, member F | -0.0546673 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0544239 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.05312 |
| RPS6 | ribosomal protein S6 | -0.050589 |
| RPS8 | ribosomal protein S8 | -0.0503263 |
| RPL23 | ribosomal protein L23 | -0.0498985 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0483146 |
| RPLP2 | ribosomal protein, large, P2 | -0.0422563 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0379788 |
| LDHB | lactate dehydrogenase B | -0.0376862 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0374014 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0363484 |
| RPS13 | ribosomal protein S13 | -0.036239 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0359394 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0355566 |
| TPI1 | triosephosphate isomerase 1 | -0.0353255 |
| RPS21 | ribosomal protein S21 | -0.0351232 |
| RPS19 | ribosomal protein S19 | -0.0348097 |
| RASAL2 | RAS protein activator like 2 | -0.0341664 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0333197 |
| RPS23 | ribosomal protein S23 | -0.0325916 |
| BCHE | butyrylcholinesterase | -0.0320179 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0314204 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | -0.0309135 |
| RPL8 | ribosomal protein L8 | -0.030554 |
| RPS29 | ribosomal protein S29 | -0.0295722 |
| RPL37A | ribosomal protein L37a | -0.0295561 |
| RPL9 | ribosomal protein L9 | -0.0295236 |
| RPL19 | ribosomal protein L19 | -0.029154 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0289803 |
| RPS14 | ribosomal protein S14 | -0.0282348 |
| RPS15 | ribosomal protein S15 | -0.0275515 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.0271269 |
| RPLP1 | ribosomal protein, large, P1 | -0.0265907 |
| S100A10 | S100 calcium binding protein A10 | -0.0264777 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0263456 |
| GNAS | GNAS complex locus | -0.0249868 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0246022 |
| RPS27 | ribosomal protein S27 | -0.0236622 |
| PRDX1 | peroxiredoxin 1 | -0.0234229 |
| RTN4 | reticulon 4 | -0.0234063 |
| TGM2 | transglutaminase 2 | -0.0233839 |
| NHSL1 | NHS-like 1 | -0.0230277 |
| HLA-A | major histocompatibility complex, class I, A | -0.0229776 |
| RPL28 | ribosomal protein L28 | -0.0229377 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.0227205 |
| RPL34 | ribosomal protein L34 | -0.0225699 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0221946 |
| RPL11 | ribosomal protein L11 | -0.02174 |
| GCG | glucagon | -0.0217355 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.021299 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0210807 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0208456 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0208409 |
| HDGF | hepatoma-derived growth factor | -0.0207852 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0205106 |
| NAV3 | neuron navigator 3 | -0.0204398 |
| TUBA1C | tubulin, alpha 1c | -0.0203901 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0200847 |
| RPS10 | ribosomal protein S10 | -0.0198958 |
| RPL15 | ribosomal protein L15 | -0.0197908 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0196463 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0192699 |
| RPS5 | ribosomal protein S5 | -0.0192668 |
| S100A11 | S100 calcium binding protein A11 | -0.019156 |
| RPL12 | ribosomal protein L12 | -0.0191279 |
| PKM | pyruvate kinase, muscle | -0.0191271 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0188015 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0187712 |
| RPS12 | ribosomal protein S12 | -0.0187199 |
| RPS26 | ribosomal protein S26 | -0.0186824 |
| CENPF | centromere protein F, 350/400kDa | -0.0186491 |
| CCND1 | cyclin D1 | -0.0186272 |
| MAP1B | microtubule-associated protein 1B | -0.0184183 |
| RPL31 | ribosomal protein L31 | -0.0184092 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0184029 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0182838 |
| COX4I1 | cytochrome c oxidase subunit IV isoform 1 | -0.0182179 |
| TRA2B | transformer 2 beta homolog (Drosophila) | -0.0181406 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.018078 |
| RAN | RAN, member RAS oncogene family | -0.0178464 |
| KIF18B | kinesin family member 18B | -0.0178339 |
| PA2G4 | proliferation-associated 2G4, 38kDa | -0.0178128 |
| RPL32 | ribosomal protein L32 | -0.0177655 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0177063 |
