| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Artemether perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Artemether_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.23187 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.151271 |
| MACC1 | metastasis associated in colon cancer 1 | 0.146742 |
| EZR | ezrin | 0.132821 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.128874 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.113398 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.101882 |
| DSCAM | Down syndrome cell adhesion molecule | 0.099835 |
| MYO1E | myosin IE | 0.0983495 |
| CANX | calnexin | 0.0761732 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0666109 |
| DSPP | dentin sialophosphoprotein | 0.0660392 |
| CCNL1 | cyclin L1 | 0.063387 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0627911 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0584459 |
| SQSTM1 | sequestosome 1 | 0.0563712 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0558482 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0549628 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0529372 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0518294 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0515916 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0501974 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.0498232 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0488646 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0481747 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0480522 |
| KLF6 | Kruppel-like factor 6 | 0.0465188 |
| JUN | jun proto-oncogene | 0.0459479 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0455572 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0445557 |
| CDHR2 | cadherin-related family member 2 | 0.0444105 |
| TJP1 | tight junction protein 1 | 0.0440558 |
| ANXA1 | annexin A1 | 0.0437195 |
| PHACTR4 | phosphatase and actin regulator 4 | 0.0435585 |
| GRK3 | G protein-coupled receptor kinase 3 | 0.0435476 |
| ZNF292 | zinc finger protein 292 | 0.043326 |
| STK24 | serine/threonine kinase 24 | 0.0426301 |
| ITPKC | inositol-trisphosphate 3-kinase C | 0.0425765 |
| IRF1 | interferon regulatory factor 1 | 0.0412735 |
| B2M | beta-2-microglobulin | 0.0412407 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0411167 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0409946 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | 0.0402987 |
| PHF3 | PHD finger protein 3 | 0.0397866 |
| DUSP10 | dual specificity phosphatase 10 | 0.0394864 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0393505 |
| SPAG9 | sperm associated antigen 9 | 0.038823 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.0384842 |
| PGK1 | phosphoglycerate kinase 1 | 0.038347 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0382868 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0376441 |
| SEC24D | SEC24 family member D | 0.0375423 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0374676 |
| GOLGB1 | golgin B1 | 0.0369061 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0362419 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0356582 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0348727 |
| SPATA13 | spermatogenesis associated 13 | 0.0344402 |
| TRIM2 | tripartite motif containing 2 | 0.0343628 |
| WEE1 | WEE1 G2 checkpoint kinase | 0.034163 |
| RRBP1 | ribosome binding protein 1 | 0.0341157 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.0331114 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0329313 |
| CALR | calreticulin | 0.032497 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.0319677 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0318532 |
| ABHD2 | abhydrolase domain containing 2 | 0.0316022 |
| CALU | calumenin | 0.0315872 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0314698 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0309209 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0308477 |
| ENO1 | enolase 1, (alpha) | 0.030776 |
| OCLN | occludin | 0.0307421 |
| TMF1 | TATA element modulatory factor 1 | 0.0300518 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0300156 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0292859 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0289192 |
| FNIP1 | folliculin interacting protein 1 | 0.0287583 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0282622 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | 0.0281244 |
| ZBTB43 | zinc finger and BTB domain containing 43 | 0.0278212 |
| MKI67 | marker of proliferation Ki-67 | 0.0277165 |
| SUCO | SUN domain containing ossification factor | 0.0276776 |
| CENPF | centromere protein F, 350/400kDa | 0.0274743 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.0264108 |
| PPARGC1A | peroxisome proliferator-activated receptor gamma, coactivator 1 alpha | 0.0263103 |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) | 0.0262135 |
| ADIPOR2 | adiponectin receptor 2 | 0.0259201 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0258131 |
| LDHA | lactate dehydrogenase A | 0.0254179 |
| PTEN | phosphatase and tensin homolog | 0.0253368 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0251874 |
| RASGEF1B | RasGEF domain family, member 1B | 0.0251847 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0251746 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0251048 |
| HLA-E | major histocompatibility complex, class I, E | 0.0248939 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0248861 |
| HDLBP | high density lipoprotein binding protein | 0.024846 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0247691 |
| UBL3 | ubiquitin-like 3 | 0.0246904 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0969678 |
| FTL | ferritin, light polypeptide | -0.0931032 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0929775 |
| INTS6 | integrator complex subunit 6 | -0.0909243 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0746467 |
| RPL35A | ribosomal protein L35a | -0.0655605 |
| RPS6 | ribosomal protein S6 | -0.0645472 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.064023 |
| LYZ | lysozyme | -0.0638114 |
| TMSB10 | thymosin beta 10 | -0.0569486 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0557369 |
| RPL23 | ribosomal protein L23 | -0.0537369 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0528344 |
| PKM | pyruvate kinase, muscle | -0.0525256 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0524131 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | -0.0508145 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0490307 |
| MT2A | metallothionein 2A | -0.0479648 |
| MAP7 | microtubule-associated protein 7 | -0.0474809 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0473308 |
| SP100 | SP100 nuclear antigen | -0.0465501 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.0456508 |
| RNF213 | ring finger protein 213 | -0.0454421 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0417882 |
| RPS8 | ribosomal protein S8 | -0.0416498 |
| RPL9 | ribosomal protein L9 | -0.0407851 |
| AREG | amphiregulin | -0.0404533 |
| PLSCR2 | phospholipid scramblase 2 | -0.0401023 |
| RPL31 | ribosomal protein L31 | -0.0397786 |
| TNS4 | tensin 4 | -0.0390498 |
| RPS29 | ribosomal protein S29 | -0.0379541 |
| RPLP1 | ribosomal protein, large, P1 | -0.0362111 |
| ACTG1 | actin gamma 1 | -0.0360958 |
| MX1 | MX dynamin-like GTPase 1 | -0.0355878 |
| HLA-B | major histocompatibility complex, class I, B | -0.0346567 |
| XAF1 | XIAP associated factor 1 | -0.0336657 |
| ASPH | aspartate beta-hydroxylase | -0.0335566 |
| STS | steroid sulfatase (microsomal), isozyme S | -0.0331073 |
| MSI2 | musashi RNA-binding protein 2 | -0.030555 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0304874 |
| RPL37A | ribosomal protein L37a | -0.0304595 |
| PTMA | prothymosin, alpha | -0.0301683 |
| RPS13 | ribosomal protein S13 | -0.0300663 |
| LCN2 | lipocalin 2 | -0.0300241 |
| BICRAL | BICRA like chromatin remodeling complex associated protein | -0.0300132 |
| RPL34 | ribosomal protein L34 | -0.0297067 |
| RPS19 | ribosomal protein S19 | -0.0293405 |
| BCL2L1 | BCL2-like 1 | -0.0292599 |
| RPS24 | ribosomal protein S24 | -0.0288535 |
| HLA-C | major histocompatibility complex, class I, C | -0.0286777 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0285408 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0282728 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0279371 |
| RPL38 | ribosomal protein L38 | -0.0279112 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0278028 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0270893 |
| RPS27 | ribosomal protein S27 | -0.0269213 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0268858 |
| SMAD3 | SMAD family member 3 | -0.0268242 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.026075 |
| RPS20 | ribosomal protein S20 | -0.0255433 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0252824 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0252563 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | -0.0251828 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0249245 |
| RPL26 | ribosomal protein L26 | -0.0248534 |
| RPS11 | ribosomal protein S11 | -0.0241526 |
| RPL19 | ribosomal protein L19 | -0.0240509 |
| RPLP2 | ribosomal protein, large, P2 | -0.0240391 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0240309 |
| RNF43 | ring finger protein 43 | -0.023947 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0238593 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0237819 |
| RPS25 | ribosomal protein S25 | -0.0237038 |
| CST3 | cystatin C | -0.0233956 |
| RPS16 | ribosomal protein S16 | -0.0232834 |
| PRKCA | protein kinase C, alpha | -0.0232593 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0232225 |
| RPS14 | ribosomal protein S14 | -0.023098 |
| RPS23 | ribosomal protein S23 | -0.0229727 |
| VIM | vimentin | -0.0229397 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0228052 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0224762 |
| S100A9 | S100 calcium binding protein A9 | -0.0224659 |
| RAB10 | RAB10, member RAS oncogene family | -0.0219054 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0218326 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.021608 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | -0.0213741 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0212808 |
| DGKH | diacylglycerol kinase, eta | -0.0209963 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0209931 |
| FRMD5 | FERM domain containing 5 | -0.0208757 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0208131 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0207372 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0205978 |
| S100P | S100 calcium binding protein P | -0.0205515 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.0205135 |
| NF1 | neurofibromin 1 | -0.0204947 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | -0.0200428 |
| RPL11 | ribosomal protein L11 | -0.0199265 |
