| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Artemether perturbation in HepG2/C3A cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Artemether_HepG2/C3A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.389737 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.297484 |
| APOB | apolipoprotein B | 0.222746 |
| FN1 | fibronectin 1 | 0.134353 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.126033 |
| C3 | complement component 3 | 0.120888 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0948511 |
| ENO1 | enolase 1, (alpha) | 0.0908912 |
| TRIM26 | tripartite motif containing 26 | 0.0846123 |
| TF | transferrin | 0.0765374 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0741381 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0721441 |
| GPAM | glycerol-3-phosphate acyltransferase, mitochondrial | 0.0692333 |
| DSPP | dentin sialophosphoprotein | 0.0639176 |
| FBF1 | Fas (TNFRSF6) binding factor 1 | 0.0638546 |
| MT2A | metallothionein 2A | 0.0635327 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | 0.0602847 |
| APOA2 | apolipoprotein A-II | 0.0592838 |
| GPC3 | glypican 3 | 0.0576455 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0554475 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0549378 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0544044 |
| AFDN | afadin, adherens junction formation factor | 0.0501777 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0492032 |
| PCBP2 | poly(rC) binding protein 2 | 0.0488491 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0475998 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0456389 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | 0.0454145 |
| CPE | carboxypeptidase E | 0.0438705 |
| JMJD1C | jumonji domain containing 1C | 0.0423919 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0422321 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) | 0.0419179 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0415271 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0401173 |
| ABCA5 | ATP-binding cassette, sub-family A (ABC1), member 5 | 0.0396344 |
| LDHA | lactate dehydrogenase A | 0.0370866 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.0350809 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0328547 |
| KIF5B | kinesin family member 5B | 0.0326606 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.03226 |
| VCL | vinculin | 0.0316984 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 0.0314213 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.0311287 |
| MED13L | mediator complex subunit 13-like | 0.0310419 |
| ARHGAP9 | Rho GTPase activating protein 9 | 0.0307716 |
| MBNL3 | muscleblind-like splicing regulator 3 | 0.0307686 |
| MALT1 | MALT1 paracaspase | 0.0306606 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0298042 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0297058 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0289531 |
| CFB | complement factor B | 0.0288536 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0276825 |
| B2M | beta-2-microglobulin | 0.0275691 |
| RBM25 | RNA binding motif protein 25 | 0.0273981 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0270073 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0267857 |
| AHSG | alpha-2-HS-glycoprotein | 0.0265872 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.0265333 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0265115 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0260478 |
| FOXO1 | forkhead box O1 | 0.0258735 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0258539 |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 | 0.0254472 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0250563 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0249594 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0245355 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.024483 |
| RTN4 | reticulon 4 | 0.0244771 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0244041 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0243435 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0243306 |
| RBM39 | RNA binding motif protein 39 | 0.0242456 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0238841 |
| TOP1 | topoisomerase (DNA) I | 0.0238523 |
| RPL11 | ribosomal protein L11 | 0.0238291 |
| PERP | PERP, TP53 apoptosis effector | 0.0237767 |
| AMBP | alpha-1-microglobulin/bikunin precursor | 0.0234109 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0232749 |
| PGK1 | phosphoglycerate kinase 1 | 0.0232466 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0229452 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0229388 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0228251 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0228141 |
| STAU1 | staufen double-stranded RNA binding protein 1 | 0.0225961 |
| GDF15 | growth differentiation factor 15 | 0.0224322 |
| NDRG1 | N-myc downstream regulated 1 | 0.0223675 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.0221751 |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | 0.0221298 |
| CRLS1 | cardiolipin synthase 1 | 0.0220083 |
| MATR3 | matrin 3 | 0.0217963 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0216673 |
| VMP1 | vacuole membrane protein 1 | 0.0213294 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.0212606 |
| HLF | hepatic leukemia factor | 0.0210268 |
| PEG10 | paternally expressed 10 | 0.0208246 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | 0.0208168 |
| VEGFA | vascular endothelial growth factor A | 0.0207865 |
| KIF1B | kinesin family member 1B | 0.0206423 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0205513 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0204771 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | -0.469822 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.126356 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0539846 |
| EHBP1 | EH domain binding protein 1 | -0.0529413 |
| GPC6 | glypican 6 | -0.049416 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0445744 |
| INTS6 | integrator complex subunit 6 | -0.0418578 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0400286 |
| GK | glycerol kinase | -0.0370093 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0359813 |
| ATXN1 | ataxin 1 | -0.0334709 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0322005 |
| ASPH | aspartate beta-hydroxylase | -0.031676 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0306241 |
| DST | dystonin | -0.0295291 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.028711 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0279196 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0257163 |
| RIGI | RNA sensor RIG-I | -0.0252346 |
| ATP10A | ATPase, class V, type 10A | -0.0244369 |
| DTNA | dystrobrevin, alpha | -0.0242729 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0241671 |
| ENKUR | enkurin, TRPC channel interacting protein | -0.0233466 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0229405 |
| MAP1B | microtubule-associated protein 1B | -0.0228428 |
| RNF213 | ring finger protein 213 | -0.022839 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0223436 |
| PTCHD4 | patched domain containing 4 | -0.0219349 |
| PLXDC2 | plexin domain containing 2 | -0.0213593 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0202739 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0200575 |
| GOLGB1 | golgin B1 | -0.0198975 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0189195 |
| SMAD3 | SMAD family member 3 | -0.018676 |
| FILIP1L | filamin A interacting protein 1-like | -0.0186401 |
| LARGE1 | LARGE xylosyl- and glucuronyltransferase 1 | -0.0186264 |
| ZHX2 | zinc fingers and homeoboxes 2 | -0.0185891 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0184688 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.0183897 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0181984 |
| HDAC4 | histone deacetylase 4 | -0.0178885 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0176824 |
| PARD3 | par-3 family cell polarity regulator | -0.0176677 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0176033 |
| FMNL2 | formin-like 2 | -0.0173715 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | -0.0171052 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0166266 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0165087 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0164858 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0163302 |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 | -0.0162193 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0161707 |
| HPCAL1 | hippocalcin-like 1 | -0.0159842 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0157004 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0155167 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0153392 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | -0.0152908 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.015055 |
| KYNU | kynureninase | -0.0150158 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0148937 |
| GNAS | GNAS complex locus | -0.0147804 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0147237 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 | -0.0146947 |
| SEPTIN9 | septin 9 | -0.0146159 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0145874 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0144371 |
| FAM13A | family with sequence similarity 13, member A | -0.0138818 |
| RAD51B | RAD51 paralog B | -0.0138038 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 | -0.0135975 |
| RPS20 | ribosomal protein S20 | -0.0135087 |
| DNAH5 | dynein, axonemal, heavy chain 5 | -0.0134023 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0133758 |
| TRMT11 | tRNA methyltransferase 11 homolog (S. cerevisiae) | -0.0132752 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0131926 |
| NHSL1 | NHS-like 1 | -0.0130151 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0130116 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 | -0.0129319 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0129237 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0128116 |
| DUSP16 | dual specificity phosphatase 16 | -0.0127061 |
| CP | ceruloplasmin (ferroxidase) | -0.012571 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0122265 |
| WNT2B | wingless-type MMTV integration site family, member 2B | -0.0120248 |
| RCC1 | regulator of chromosome condensation 1 | -0.0120114 |
| PALLD | palladin, cytoskeletal associated protein | -0.0119703 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | -0.0119444 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0117986 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.0117696 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | -0.0116791 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0115724 |
| ZBTB10 | zinc finger and BTB domain containing 10 | -0.0113743 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0112853 |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like | -0.0112042 |
| RSRP1 | arginine/serine-rich protein 1 | -0.0110505 |
| HSPA8 | heat shock 70kDa protein 8 | -0.0109492 |
| SYN3 | synapsin III | -0.0108699 |
| RPS24 | ribosomal protein S24 | -0.0108577 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | -0.0108422 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0108358 |
| PMM2 | phosphomannomutase 2 | -0.0107597 |
