| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Artemether perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Artemether_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.123427 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.118972 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.117458 |
| FMNL2 | formin-like 2 | 0.0892631 |
| VIM | vimentin | 0.0865057 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0853669 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0765409 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0749883 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0724027 |
| COPA | coatomer protein complex, subunit alpha | 0.0722985 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0714179 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0690365 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0688454 |
| TPM3 | tropomyosin 3 | 0.0681385 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0681058 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.067557 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0675463 |
| APP | amyloid beta (A4) precursor protein | 0.0654279 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0644328 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0613003 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0599985 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0593683 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0593351 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0590724 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0578893 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0564212 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0561277 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0555443 |
| MSN | moesin | 0.0544104 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0538076 |
| FLNB | filamin B, beta | 0.0535315 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.052879 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0525051 |
| TPD52 | tumor protein D52 | 0.0519602 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0518576 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0517564 |
| GLG1 | golgi glycoprotein 1 | 0.0513761 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0512931 |
| RBM39 | RNA binding motif protein 39 | 0.0490382 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0485787 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0481796 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0466707 |
| ERBIN | erbb2 interacting protein | 0.04659 |
| GOLGA4 | golgin A4 | 0.0457023 |
| MATR3 | matrin 3 | 0.0450528 |
| ENO1 | enolase 1, (alpha) | 0.0446726 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0444066 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0440605 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0437689 |
| RBM25 | RNA binding motif protein 25 | 0.0437122 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0435303 |
| WDR43 | WD repeat domain 43 | 0.0427933 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0427207 |
| RNF145 | ring finger protein 145 | 0.0423924 |
| POTEF | POTE ankyrin domain family, member F | 0.0420539 |
| COG5 | component of oligomeric golgi complex 5 | 0.0420027 |
| ECT2 | epithelial cell transforming 2 | 0.0418023 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0414184 |
| PYGL | phosphorylase, glycogen, liver | 0.0405009 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0401379 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.040021 |
| CFDP1 | craniofacial development protein 1 | 0.0398542 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0394851 |
| FNBP1L | formin binding protein 1-like | 0.0387296 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0387049 |
| CCNL1 | cyclin L1 | 0.0384419 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0382911 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0381592 |
| ANXA1 | annexin A1 | 0.0380653 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0380382 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0376713 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0375941 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0375908 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.036997 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0367682 |
| RAB18 | RAB18, member RAS oncogene family | 0.0366699 |
| CANX | calnexin | 0.0366324 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0364854 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0362411 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0362066 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0356957 |
| PTK2 | protein tyrosine kinase 2 | 0.0355651 |
| FAM107B | family with sequence similarity 107, member B | 0.0355196 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0354134 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0352331 |
| SETD5 | SET domain containing 5 | 0.0346754 |
| PGK1 | phosphoglycerate kinase 1 | 0.0346649 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0341871 |
| FTO | fat mass and obesity associated | 0.034081 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0340344 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0340208 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0339738 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.033965 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0337643 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0336966 |
| CDC73 | cell division cycle 73 | 0.0335949 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0335122 |
| SLMAP | sarcolemma associated protein | 0.033436 |
| HELZ | helicase with zinc finger | 0.0327826 |
| SBF2 | SET binding factor 2 | 0.0327102 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PM20D1 | peptidase M20 domain containing 1 | -0.217997 |
| GRAMD1B | GRAM domain containing 1B | -0.17488 |
| FTL | ferritin, light polypeptide | -0.149634 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.143677 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.114952 |
| TXNRD1 | thioredoxin reductase 1 | -0.105199 |
| TMSB10 | thymosin beta 10 | -0.0875529 |
| MT2A | metallothionein 2A | -0.0861963 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0835977 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0769025 |
| IGF2 | insulin-like growth factor 2 | -0.0594961 |
| OSMR | oncostatin M receptor | -0.0555435 |
| EGR1 | early growth response 1 | -0.0546261 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0514841 |
| BICC1 | BicC family RNA binding protein 1 | -0.0483916 |
| RPL23 | ribosomal protein L23 | -0.0460122 |
| WWOX | WW domain containing oxidoreductase | -0.0450334 |
| RPLP1 | ribosomal protein, large, P1 | -0.0412958 |
| NTN4 | netrin 4 | -0.0409839 |
| RPS8 | ribosomal protein S8 | -0.0383685 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0371963 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0341086 |
| RPS19 | ribosomal protein S19 | -0.0336941 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0323454 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0322545 |
| RSPO3 | R-spondin 3 | -0.0317057 |
| RPS29 | ribosomal protein S29 | -0.0314668 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0307683 |
| KYNU | kynureninase | -0.0300355 |
| RPL36 | ribosomal protein L36 | -0.0298677 |
| NAV3 | neuron navigator 3 | -0.0298299 |
| EFNA5 | ephrin-A5 | -0.0297086 |
| HDAC9 | histone deacetylase 9 | -0.0291828 |
| ZNF804A | zinc finger protein 804A | -0.0286537 |
| RPL19 | ribosomal protein L19 | -0.0273516 |
| MTHFD2L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like | -0.0258084 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0257188 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | -0.0253957 |
| NRG1 | neuregulin 1 | -0.025346 |
| BMP5 | bone morphogenetic protein 5 | -0.0249594 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | -0.0248656 |
| RPS21 | ribosomal protein S21 | -0.0246099 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | -0.0244996 |
| NSUN6 | NOP2/Sun domain family, member 6 | -0.0236923 |
| NNMT | nicotinamide N-methyltransferase | -0.0235106 |
| GLIS3 | GLIS family zinc finger 3 | -0.0228263 |
| TDP2 | tyrosyl-DNA phosphodiesterase 2 | -0.0227775 |
| ABCC2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 | -0.0227357 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | -0.0226576 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | -0.0218273 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0218012 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0214714 |
| NABP1 | nucleic acid binding protein 1 | -0.0213903 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0210491 |
| RNF213 | ring finger protein 213 | -0.020841 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0206264 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.0204517 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0199354 |
| RPL28 | ribosomal protein L28 | -0.0196686 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0192976 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.019177 |
| PDE10A | phosphodiesterase 10A | -0.0190053 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0187889 |
| RPL35A | ribosomal protein L35a | -0.0184922 |
| NEGR1 | neuronal growth regulator 1 | -0.0181591 |
| ASPH | aspartate beta-hydroxylase | -0.0179026 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0178704 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0178497 |
| SVIL | supervillin | -0.0176687 |
| RPL38 | ribosomal protein L38 | -0.0176376 |
| RPS20 | ribosomal protein S20 | -0.0175923 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0173409 |
| HMGB1 | high mobility group box 1 | -0.0172209 |
| RPS2 | ribosomal protein S2 | -0.0171805 |
| RPS25 | ribosomal protein S25 | -0.017081 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | -0.0170021 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0169918 |
| CCL2 | chemokine (C-C motif) ligand 2 | -0.016929 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0168113 |
| FGG | fibrinogen gamma chain | -0.0168099 |
| RPL37A | ribosomal protein L37a | -0.0167291 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0166806 |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 | -0.0163182 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0162913 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0161622 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0160743 |
| STAU2 | staufen double-stranded RNA binding protein 2 | -0.0160419 |
| FGB | fibrinogen beta chain | -0.0160034 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.0159962 |
| SSH1 | slingshot protein phosphatase 1 | -0.0156436 |
| RPL8 | ribosomal protein L8 | -0.0155537 |
| KLF6 | Kruppel-like factor 6 | -0.0153691 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0151948 |
| METAP2 | methionyl aminopeptidase 2 | -0.015035 |
| AREG | amphiregulin | -0.0150081 |
| RPS12 | ribosomal protein S12 | -0.0150004 |
| RPS14 | ribosomal protein S14 | -0.014973 |
| TRAPPC9 | trafficking protein particle complex 9 | -0.0148458 |
| SERF2 | small EDRK-rich factor 2 | -0.0148024 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0147465 |
