| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Artemether perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Artemether_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0758398 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0655745 |
| RBM25 | RNA binding motif protein 25 | 0.0629099 |
| PGK1 | phosphoglycerate kinase 1 | 0.06075 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0591524 |
| GOLGA4 | golgin A4 | 0.0529096 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0512985 |
| HMGA2 | high mobility group AT-hook 2 | 0.0485885 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | 0.0467233 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0464148 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0462361 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0454187 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0441607 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0440645 |
| SET | SET nuclear proto-oncogene | 0.0425613 |
| TMF1 | TATA element modulatory factor 1 | 0.0414303 |
| ELP2 | elongator acetyltransferase complex subunit 2 | 0.0413185 |
| RAD51B | RAD51 paralog B | 0.0411556 |
| XPO1 | exportin 1 | 0.0397877 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0388892 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0386799 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0384857 |
| TBCK | TBC1 domain containing kinase | 0.0382963 |
| LAMA4 | laminin, alpha 4 | 0.0382693 |
| ATP13A3 | ATPase type 13A3 | 0.0380807 |
| FAM3C | family with sequence similarity 3, member C | 0.0369218 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0368931 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0367989 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0367408 |
| RORA | RAR-related orphan receptor A | 0.0366566 |
| SPIDR | scaffolding protein involved in DNA repair | 0.0359916 |
| CALR | calreticulin | 0.0359581 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0358584 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0356283 |
| CD44 | CD44 molecule (Indian blood group) | 0.0354764 |
| CD36 | CD36 molecule (thrombospondin receptor) | 0.0354107 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0354004 |
| POLA1 | polymerase (DNA directed), alpha 1, catalytic subunit | 0.0351806 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0350905 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0346143 |
| CANX | calnexin | 0.0344839 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.034441 |
| SPAG9 | sperm associated antigen 9 | 0.0342009 |
| ACTN4 | actinin, alpha 4 | 0.0338625 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0336769 |
| FMNL2 | formin-like 2 | 0.0334135 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0332435 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0329881 |
| NUP58 | nucleoporin 58 | 0.0329067 |
| ITGA6 | integrin, alpha 6 | 0.0328404 |
| ENO1 | enolase 1, (alpha) | 0.0327838 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | 0.0327256 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | 0.0324482 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | 0.0324332 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.031552 |
| HELZ | helicase with zinc finger | 0.0315254 |
| SBF2 | SET binding factor 2 | 0.0314414 |
| CLTC | clathrin, heavy chain (Hc) | 0.0314108 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0312155 |
| PKN2 | protein kinase N2 | 0.0312049 |
| USP32 | ubiquitin specific peptidase 32 | 0.0305526 |
| ZNF292 | zinc finger protein 292 | 0.0301645 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.030144 |
| ZNF644 | zinc finger protein 644 | 0.0299926 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0299566 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0296282 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.029568 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0295619 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0295171 |
| CDC73 | cell division cycle 73 | 0.0292242 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0290095 |
| HDLBP | high density lipoprotein binding protein | 0.028996 |
| FN1 | fibronectin 1 | 0.0289934 |
| AGTPBP1 | ATP/GTP binding protein 1 | 0.0288737 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0287357 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0286677 |
| RC3H1 | ring finger and CCCH-type domains 1 | 0.0286574 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0286012 |
| AHCTF1 | AT hook containing transcription factor 1 | 0.0285546 |
| CRY1 | cryptochrome circadian clock 1 | 0.0285143 |
| UPF2 | UPF2 regulator of nonsense transcripts homolog (yeast) | 0.0284096 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0280224 |
| GRAMD1B | GRAM domain containing 1B | 0.0279985 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | 0.0279791 |
| RNF145 | ring finger protein 145 | 0.027818 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0274838 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0274725 |
| AHCYL1 | adenosylhomocysteinase-like 1 | 0.0274594 |
| FAM13A | family with sequence similarity 13, member A | 0.0274533 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0274136 |
| CSNK2A2 | casein kinase 2, alpha prime polypeptide | 0.0272325 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0271086 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.026926 |
| PHF3 | PHD finger protein 3 | 0.0269061 |
| CDK8 | cyclin-dependent kinase 8 | 0.0266799 |
| UBE2G1 | ubiquitin-conjugating enzyme E2G 1 | 0.0266012 |
| IL6ST | interleukin 6 signal transducer | 0.0264167 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0261922 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0261312 |
| INHBA | inhibin, beta A | 0.0259695 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.155857 |
| KRT17 | keratin 17, type I | -0.109284 |
| MUC16 | mucin 16, cell surface associated | -0.102728 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0951028 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0911465 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.083798 |
| STAT6 | signal transducer and activator of transcription 6, interleukin-4 induced | -0.0837478 |
| LMO7 | LIM domain 7 | -0.0823203 |
| FTL | ferritin, light polypeptide | -0.0776049 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0735176 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0725101 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0716927 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0712634 |
| S100A9 | S100 calcium binding protein A9 | -0.0691532 |
| TMSB10 | thymosin beta 10 | -0.0679376 |
| ATOSA | atos homolog A | -0.0673943 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0671166 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0670218 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0658362 |
| MYO1E | myosin IE | -0.061512 |
| LAMB3 | laminin, beta 3 | -0.0609215 |
| RPL35A | ribosomal protein L35a | -0.0580206 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0572976 |
| ABHD17C | abhydrolase domain containing 17C | -0.0568509 |
| TPM4 | tropomyosin 4 | -0.0561267 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0545037 |
| ERBIN | erbb2 interacting protein | -0.0535772 |
| RPS25 | ribosomal protein S25 | -0.0516991 |
| RPS6 | ribosomal protein S6 | -0.0512296 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | -0.0504502 |
| RPS16 | ribosomal protein S16 | -0.0492467 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0488282 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0484313 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0480021 |
| ASPH | aspartate beta-hydroxylase | -0.0468527 |
| RPS12 | ribosomal protein S12 | -0.0456867 |
| RPLP0 | ribosomal protein, large, P0 | -0.0455588 |
| RPL15 | ribosomal protein L15 | -0.0453155 |
| RPL37A | ribosomal protein L37a | -0.0452889 |
| KATNBL1 | katanin p80 subunit B-like 1 | -0.0451907 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0450796 |
| TJP1 | tight junction protein 1 | -0.0444601 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0440948 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0433121 |
| RPS17 | ribosomal protein S17 | -0.0424545 |
| RPS8 | ribosomal protein S8 | -0.0423461 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0419852 |
| KYNU | kynureninase | -0.0415286 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0415137 |
| RBM47 | RNA binding motif protein 47 | -0.0411867 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0405443 |
| DOCK4 | dedicator of cytokinesis 4 | -0.040004 |
| JMJD1C | jumonji domain containing 1C | -0.0396978 |
| RCOR1 | REST corepressor 1 | -0.0390678 |
| NDRG1 | N-myc downstream regulated 1 | -0.0379862 |
| S100A6 | S100 calcium binding protein A6 | -0.0378207 |
| NABP1 | nucleic acid binding protein 1 | -0.0375476 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0361938 |
| RPS24 | ribosomal protein S24 | -0.0361676 |
| WASF2 | WAS protein family, member 2 | -0.0358471 |
| RPL26 | ribosomal protein L26 | -0.0347551 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0342358 |
| RPL28 | ribosomal protein L28 | -0.034168 |
| CSTB | cystatin B (stefin B) | -0.0340185 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0339319 |
| ANXA2 | annexin A2 | -0.0337213 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.03368 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | -0.0335166 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0333524 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0332082 |
| RPLP2 | ribosomal protein, large, P2 | -0.0330233 |
| MCL1 | myeloid cell leukemia 1 | -0.0323358 |
| RPS20 | ribosomal protein S20 | -0.0322125 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0321682 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0316867 |
| VIM | vimentin | -0.0312778 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0305734 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -0.0299975 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0298871 |
| TUFT1 | tuftelin 1 | -0.0298419 |
| MYO5B | myosin VB | -0.0296601 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0296319 |
| UBC | ubiquitin C | -0.0296148 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0291479 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0290793 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0285123 |
| MAPK6 | mitogen-activated protein kinase 6 | -0.0284009 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0282059 |
| USP34 | ubiquitin specific peptidase 34 | -0.0279185 |
| SVIL | supervillin | -0.0279155 |
| TMOD3 | tropomodulin 3 (ubiquitous) | -0.0277682 |
| RPL31 | ribosomal protein L31 | -0.0277349 |
| ERGIC1 | endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 | -0.0276279 |
| OSMR | oncostatin M receptor | -0.0274383 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0269886 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0264144 |
| RPL37 | ribosomal protein L37 | -0.0262169 |
| RREB1 | ras responsive element binding protein 1 | -0.0261174 |
| POTEF | POTE ankyrin domain family, member F | -0.0257142 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0256507 |
