| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Artemether perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Artemether_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.31496 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.179349 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.118916 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.106272 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.101969 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0922211 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0907624 |
| MCL1 | myeloid cell leukemia 1 | 0.090266 |
| TPI1 | triosephosphate isomerase 1 | 0.0712377 |
| TXNRD1 | thioredoxin reductase 1 | 0.0682957 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0682158 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0627141 |
| KRT18 | keratin 18, type I | 0.0614592 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0604948 |
| TPM3 | tropomyosin 3 | 0.0596855 |
| ENO1 | enolase 1, (alpha) | 0.0586231 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0563357 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0559922 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.055536 |
| UBC | ubiquitin C | 0.0544041 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0542242 |
| PCBP2 | poly(rC) binding protein 2 | 0.0529754 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0523103 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.0514485 |
| IPO7 | importin 7 | 0.0486218 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0483449 |
| CLTC | clathrin, heavy chain (Hc) | 0.0480293 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0467293 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0464246 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0448699 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0447475 |
| RPLP0 | ribosomal protein, large, P0 | 0.0432849 |
| MSN | moesin | 0.0422521 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0420675 |
| PGK1 | phosphoglycerate kinase 1 | 0.0419943 |
| MKI67 | marker of proliferation Ki-67 | 0.0415068 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0398185 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | 0.039735 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0397308 |
| HSPA8 | heat shock 70kDa protein 8 | 0.039084 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0385481 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0370674 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0369893 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0369618 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0364481 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0359517 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0356637 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0354856 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0353462 |
| RRM2 | ribonucleotide reductase M2 | 0.0352355 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0348068 |
| RPL3 | ribosomal protein L3 | 0.0347617 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0346136 |
| VMP1 | vacuole membrane protein 1 | 0.0345293 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0344158 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0343252 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.0337622 |
| SET | SET nuclear proto-oncogene | 0.0336603 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0329789 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0329575 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0329554 |
| SPAG9 | sperm associated antigen 9 | 0.0328847 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0327775 |
| CANX | calnexin | 0.0326378 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0325215 |
| ADAR | adenosine deaminase, RNA-specific | 0.0325063 |
| BRD2 | bromodomain containing 2 | 0.0324339 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.032214 |
| VIM | vimentin | 0.0321701 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0319936 |
| MATR3 | matrin 3 | 0.0319489 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0318279 |
| GDI2 | GDP dissociation inhibitor 2 | 0.0317808 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0317689 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.031422 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0308543 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0308448 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0307731 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0307151 |
| TUBA1B | tubulin, alpha 1b | 0.0305095 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0298195 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0297581 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.029705 |
| ANO6 | anoctamin 6 | 0.028511 |
| SERINC3 | serine incorporator 3 | 0.028287 |
| DST | dystonin | 0.0282354 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0280742 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0277676 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0276859 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0276463 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0274254 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0273096 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.027258 |
| JMJD1C | jumonji domain containing 1C | 0.0270056 |
| ERBIN | erbb2 interacting protein | 0.026814 |
| LDHA | lactate dehydrogenase A | 0.026738 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0266559 |
| PTMA | prothymosin, alpha | 0.0265977 |
| TLN1 | talin 1 | 0.0263645 |
| TPX2 | TPX2, microtubule-associated | 0.02632 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.0957087 |
| RPL35A | ribosomal protein L35a | -0.0699709 |
| PDE10A | phosphodiesterase 10A | -0.0582225 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0562555 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0527112 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0499212 |
| OSMR | oncostatin M receptor | -0.0496503 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0457587 |
| FTL | ferritin, light polypeptide | -0.0455183 |
| TMEM165 | transmembrane protein 165 | -0.0419579 |
| HLA-B | major histocompatibility complex, class I, B | -0.0411843 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0395402 |
| RBM39 | RNA binding motif protein 39 | -0.0385334 |
| RPS8 | ribosomal protein S8 | -0.0375598 |
| ATP11A | ATPase, class VI, type 11A | -0.0372391 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0353041 |
| MT2A | metallothionein 2A | -0.0343471 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.034099 |
| RPLP1 | ribosomal protein, large, P1 | -0.033504 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.03242 |
| GNAS | GNAS complex locus | -0.0309833 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0305466 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0303847 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0289744 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0288448 |
| RPL34 | ribosomal protein L34 | -0.0286476 |
| DEK | DEK proto-oncogene | -0.0285573 |
| IGF2 | insulin-like growth factor 2 | -0.0284891 |
| RSF1 | remodeling and spacing factor 1 | -0.0281031 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0276243 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0267835 |
| PHF21A | PHD finger protein 21A | -0.0263929 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0261661 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0261554 |
| SVIL | supervillin | -0.02592 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0255328 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0252315 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0249721 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0244813 |
| RPL38 | ribosomal protein L38 | -0.0243315 |
| RPS21 | ribosomal protein S21 | -0.0240726 |
| WDR70 | WD repeat domain 70 | -0.0237791 |
| THOC2 | THO complex 2 | -0.0235344 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0235205 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | -0.0232657 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0229761 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0229281 |
| RPL36 | ribosomal protein L36 | -0.0227476 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0224964 |
| RPS19 | ribosomal protein S19 | -0.0221771 |
| RPL9 | ribosomal protein L9 | -0.0217807 |
| DHX57 | DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 | -0.0216003 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0215959 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.0214487 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0212126 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0211331 |
| HLA-A | major histocompatibility complex, class I, A | -0.0210065 |
| ENOSF1 | enolase superfamily member 1 | -0.0209986 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0209623 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) | -0.0209286 |
| AGRN | agrin | -0.0208537 |
| RPLP2 | ribosomal protein, large, P2 | -0.0207351 |
| RPS29 | ribosomal protein S29 | -0.0206195 |
| STAT2 | signal transducer and activator of transcription 2, 113kDa | -0.0204761 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | -0.020435 |
| CDK2AP2 | cyclin-dependent kinase 2 associated protein 2 | -0.020394 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.0203124 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0202736 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0201941 |
| PPIG | peptidylprolyl isomerase G (cyclophilin G) | -0.020043 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0200064 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0199818 |
| RPL26 | ribosomal protein L26 | -0.0199693 |
| RPL37 | ribosomal protein L37 | -0.0197591 |
| EGR1 | early growth response 1 | -0.0197547 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.019499 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | -0.0194339 |
| RPL8 | ribosomal protein L8 | -0.0194157 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.018859 |
| MT1X | metallothionein 1X | -0.0185586 |
| GOLGA4 | golgin A4 | -0.0184771 |
| GOSR1 | golgi SNAP receptor complex member 1 | -0.0184071 |
| NSRP1 | nuclear speckle splicing regulatory protein 1 | -0.0183728 |
| TPM2 | tropomyosin 2 (beta) | -0.0183607 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0182906 |
| RPS15 | ribosomal protein S15 | -0.0182881 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0181711 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0180183 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0179363 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0178229 |
| RPL37A | ribosomal protein L37a | -0.0177201 |
| ATXN1 | ataxin 1 | -0.0175599 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.01738 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0173753 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0173263 |
| RIGI | RNA sensor RIG-I | -0.0171475 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0169987 |
| RPL32 | ribosomal protein L32 | -0.0169942 |
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | -0.0168201 |
| YBX3 | Y box binding protein 3 | -0.016792 |
