| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Artemether perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Artemether_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.102524 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0915398 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0908936 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0857621 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0853557 |
| EFNA5 | ephrin-A5 | 0.0836102 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0829502 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.082527 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0777293 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0765655 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0762817 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0738539 |
| GOLGB1 | golgin B1 | 0.0717336 |
| PRELID2 | PRELI domain containing 2 | 0.0715013 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0706098 |
| RUNX1 | runt-related transcription factor 1 | 0.0703355 |
| ITGA6 | integrin, alpha 6 | 0.0676463 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0674634 |
| OGA | O-GlcNAcase | 0.0644367 |
| CTBP2 | C-terminal binding protein 2 | 0.0642975 |
| FNDC3B | fibronectin type III domain containing 3B | 0.062344 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0606362 |
| COL5A2 | collagen, type V, alpha 2 | 0.059887 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0589905 |
| RPL37 | ribosomal protein L37 | 0.0553934 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.054526 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0539651 |
| GOLGA4 | golgin A4 | 0.0528733 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | 0.0528321 |
| FTL | ferritin, light polypeptide | 0.052779 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0527466 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0517575 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0515412 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0505813 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0495769 |
| CD109 | CD109 molecule | 0.0485317 |
| SBF2 | SET binding factor 2 | 0.0483304 |
| ASPH | aspartate beta-hydroxylase | 0.048258 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | 0.0476082 |
| ERBIN | erbb2 interacting protein | 0.046187 |
| RASA2 | RAS p21 protein activator 2 | 0.0460717 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0460552 |
| STC1 | stanniocalcin 1 | 0.0459343 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0456512 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0456149 |
| SCFD1 | sec1 family domain containing 1 | 0.045399 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0453106 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0452088 |
| JMJD1C | jumonji domain containing 1C | 0.044068 |
| FOXP1 | forkhead box P1 | 0.043592 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0432997 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0425809 |
| RBM39 | RNA binding motif protein 39 | 0.0415904 |
| FNIP1 | folliculin interacting protein 1 | 0.0412602 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0412463 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0412 |
| CCNL1 | cyclin L1 | 0.0410004 |
| JAK1 | Janus kinase 1 | 0.0409789 |
| AUTS2 | autism susceptibility candidate 2 | 0.0405307 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0404819 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.040116 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0400321 |
| FAM13A | family with sequence similarity 13, member A | 0.0396836 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0396815 |
| PRKCA | protein kinase C, alpha | 0.0394888 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0394058 |
| TPM4 | tropomyosin 4 | 0.039158 |
| B2M | beta-2-microglobulin | 0.0391186 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0386349 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0385377 |
| RORA | RAR-related orphan receptor A | 0.0381938 |
| CANX | calnexin | 0.0375775 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0374102 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0373877 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 0.0372048 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0367631 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0367541 |
| TMSB4X | thymosin beta 4, X-linked | 0.0367209 |
| NBAS | neuroblastoma amplified sequence | 0.0366471 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0357944 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0357113 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | 0.0356287 |
| RPLP1 | ribosomal protein, large, P1 | 0.0354709 |
| MTREX | Mtr4 exosome RNA helicase | 0.0347947 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0343704 |
| MT2A | metallothionein 2A | 0.0341633 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0341268 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0341015 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0339364 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.0339135 |
| KIF5B | kinesin family member 5B | 0.0336059 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0330953 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0329538 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0329083 |
| TOP1 | topoisomerase (DNA) I | 0.0327092 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.032085 |
| SVIL | supervillin | 0.0317564 |
| EHBP1 | EH domain binding protein 1 | 0.0315057 |
| AGTPBP1 | ATP/GTP binding protein 1 | 0.0314908 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0313675 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.289741 |
| GPC6 | glypican 6 | -0.117726 |
| UBC | ubiquitin C | -0.103257 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0926574 |
| DST | dystonin | -0.0896024 |
| RPL23 | ribosomal protein L23 | -0.0885329 |
| ANXA2 | annexin A2 | -0.080214 |
| PTMA | prothymosin, alpha | -0.0787216 |
| ACTG1 | actin gamma 1 | -0.0777663 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0758277 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.074512 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0731117 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.070352 |
| NDRG1 | N-myc downstream regulated 1 | -0.0683837 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | -0.0634249 |
| RPS3 | ribosomal protein S3 | -0.0615917 |
| RTN4 | reticulon 4 | -0.0615567 |
| RPS27A | ribosomal protein S27a | -0.0601071 |
| VMP1 | vacuole membrane protein 1 | -0.059472 |
| PKM | pyruvate kinase, muscle | -0.0571513 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0571314 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0565764 |
| CD44 | CD44 molecule (Indian blood group) | -0.0560003 |
| VEZT | vezatin, adherens junctions transmembrane protein | -0.0558515 |
| NUP58 | nucleoporin 58 | -0.0549794 |
| SMYD3 | SET and MYND domain containing 3 | -0.0516997 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0500735 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0500074 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0497046 |
| TMSB10 | thymosin beta 10 | -0.0492241 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0486934 |
| CD2AP | CD2-associated protein | -0.0480112 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0463914 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0462135 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0454729 |
| VIM | vimentin | -0.0453343 |
| LDHA | lactate dehydrogenase A | -0.0450277 |
| MED13L | mediator complex subunit 13-like | -0.0448954 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0445517 |
| HIPK3 | homeodomain interacting protein kinase 3 | -0.0432235 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0431233 |
| RPL35A | ribosomal protein L35a | -0.0429902 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0425257 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0418195 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.041159 |
| NEK7 | NIMA-related kinase 7 | -0.0406507 |
| KAZN | kazrin, periplakin interacting protein | -0.0398679 |
| ACTN4 | actinin, alpha 4 | -0.039842 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0396898 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0396121 |
| AGO3 | argonaute RISC catalytic component 3 | -0.0384099 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0380344 |
| SWAP70 | SWAP switching B-cell complex 70kDa subunit | -0.0368631 |
| ACTN1 | actinin, alpha 1 | -0.0367109 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.035927 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | -0.0354124 |
| RIOK3 | RIO kinase 3 | -0.0353622 |
| RBM25 | RNA binding motif protein 25 | -0.035104 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0342173 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0340018 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0335197 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.03301 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0327813 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0327376 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0325287 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0322092 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0320442 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0319513 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0317768 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0314629 |
| CCNY | cyclin Y | -0.0310637 |
| MYO6 | myosin VI | -0.0310486 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.030939 |
| RPS8 | ribosomal protein S8 | -0.0308488 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0304653 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0303989 |
| CCND1 | cyclin D1 | -0.0303342 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0303036 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0302593 |
| RBBP6 | retinoblastoma binding protein 6 | -0.0298298 |
| NCOA1 | nuclear receptor coactivator 1 | -0.0297193 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0297055 |
| MAP4 | microtubule-associated protein 4 | -0.0296168 |
| CUL5 | cullin 5 | -0.0293007 |
| DENND4C | DENN/MADD domain containing 4C | -0.0292138 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0288924 |
| RPLP0 | ribosomal protein, large, P0 | -0.0288063 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | -0.0284243 |
| RPL5 | ribosomal protein L5 | -0.028412 |
| GNAS | GNAS complex locus | -0.0283264 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 | -0.0282418 |
| RLF | rearranged L-myc fusion | -0.02812 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0280357 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | -0.0276139 |
| MYO9A | myosin IXA | -0.0275893 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0275231 |
| MED13 | mediator complex subunit 13 | -0.0273193 |
| PGK1 | phosphoglycerate kinase 1 | -0.0272867 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0272226 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0271686 |
