| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Artesunate perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Artesunate_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.247903 |
| PODXL | podocalyxin-like | 0.204988 |
| LDHA | lactate dehydrogenase A | 0.17131 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.160513 |
| CDH13 | cadherin 13 | 0.140852 |
| PLAT | plasminogen activator, tissue | 0.10691 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.10634 |
| FLNA | filamin A, alpha | 0.0968367 |
| COL5A1 | collagen, type V, alpha 1 | 0.0957827 |
| CANX | calnexin | 0.088525 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0860937 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0836925 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0796248 |
| MAP1B | microtubule-associated protein 1B | 0.0784754 |
| PRSS23 | protease, serine, 23 | 0.0748952 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0747928 |
| MSN | moesin | 0.074085 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0718487 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0712681 |
| TPM3 | tropomyosin 3 | 0.0711147 |
| ASPH | aspartate beta-hydroxylase | 0.0711146 |
| FLNB | filamin B, beta | 0.0653336 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0652004 |
| APP | amyloid beta (A4) precursor protein | 0.0639126 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0628337 |
| MCL1 | myeloid cell leukemia 1 | 0.0625184 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0624021 |
| PLEC | plectin | 0.0568986 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0543618 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0510137 |
| HDAC9 | histone deacetylase 9 | 0.0501043 |
| CD44 | CD44 molecule (Indian blood group) | 0.0499348 |
| CALR | calreticulin | 0.049568 |
| TPM4 | tropomyosin 4 | 0.049511 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0494855 |
| CENPF | centromere protein F, 350/400kDa | 0.0487751 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0486647 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0479722 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0476704 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0467774 |
| NAV1 | neuron navigator 1 | 0.0451169 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0445915 |
| VEGFA | vascular endothelial growth factor A | 0.0433267 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0433049 |
| SEPTIN9 | septin 9 | 0.0420283 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0418279 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0410282 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0396284 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0393511 |
| FSTL1 | follistatin-like 1 | 0.038928 |
| SET | SET nuclear proto-oncogene | 0.0385998 |
| RRM2 | ribonucleotide reductase M2 | 0.0378166 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0375174 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0360187 |
| CYTH3 | cytohesin 3 | 0.0358446 |
| DCLK2 | doublecortin-like kinase 2 | 0.0350707 |
| RPL3 | ribosomal protein L3 | 0.0349125 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | 0.0344988 |
| MKI67 | marker of proliferation Ki-67 | 0.03437 |
| DGKG | diacylglycerol kinase, gamma 90kDa | 0.0336626 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0333645 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.032759 |
| FN1 | fibronectin 1 | 0.0325389 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0325107 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0321961 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0319512 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0318218 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.031634 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0311397 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 | 0.0305968 |
| SMAD3 | SMAD family member 3 | 0.0303426 |
| EFNA5 | ephrin-A5 | 0.0296993 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0296915 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0296255 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0295332 |
| ACTN1 | actinin, alpha 1 | 0.0287161 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0283322 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.0282208 |
| ERBIN | erbb2 interacting protein | 0.0280278 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0275186 |
| AXL | AXL receptor tyrosine kinase | 0.0274359 |
| DSPP | dentin sialophosphoprotein | 0.0272013 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0271921 |
| TAGLN2 | transgelin 2 | 0.0269747 |
| COPA | coatomer protein complex, subunit alpha | 0.0268069 |
| EZR | ezrin | 0.0267781 |
| IQGAP3 | IQ motif containing GTPase activating protein 3 | 0.0264842 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0264481 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0264174 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0258757 |
| PKM | pyruvate kinase, muscle | 0.0258614 |
| MYOF | myoferlin | 0.0258402 |
| TNNT1 | troponin T type 1 (skeletal, slow) | 0.0257361 |
| SPDL1 | spindle apparatus coiled-coil protein 1 | 0.0256588 |
| OBSCN | obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF | 0.0255186 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0255005 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0254548 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0249862 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0248604 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0247482 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.185092 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.18115 |
| VIM | vimentin | -0.16562 |
| LOX | lysyl oxidase | -0.148715 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.132648 |
| FBN1 | fibrillin 1 | -0.0792897 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0757755 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0648753 |
| HLA-B | major histocompatibility complex, class I, B | -0.0648685 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0591157 |
| CSTB | cystatin B (stefin B) | -0.0510481 |
| PTMA | prothymosin, alpha | -0.0494805 |
| MEIS2 | Meis homeobox 2 | -0.0490163 |
| COL1A2 | collagen, type I, alpha 2 | -0.047847 |
| UBC | ubiquitin C | -0.047789 |
| GPC6 | glypican 6 | -0.0461638 |
| THBS2 | thrombospondin 2 | -0.0458485 |
| MX2 | MX dynamin-like GTPase 2 | -0.0446084 |
| AUTS2 | autism susceptibility candidate 2 | -0.0436032 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0420759 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0413177 |
| S100A6 | S100 calcium binding protein A6 | -0.0412539 |
| S100A10 | S100 calcium binding protein A10 | -0.0397987 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0389213 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0378426 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0354375 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0343344 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.033283 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0325481 |
| SBF2 | SET binding factor 2 | -0.0321504 |
| B2M | beta-2-microglobulin | -0.0318986 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0309823 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0307584 |
| RPS24 | ribosomal protein S24 | -0.0303463 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0303373 |
| FRMD5 | FERM domain containing 5 | -0.0302797 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0292134 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0286088 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0284417 |
| FTL | ferritin, light polypeptide | -0.028107 |
| ACTG1 | actin gamma 1 | -0.0280572 |
| HLA-E | major histocompatibility complex, class I, E | -0.0277364 |
| RPS6 | ribosomal protein S6 | -0.0272712 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0271127 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0264883 |
| SQSTM1 | sequestosome 1 | -0.0264763 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0261646 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0258851 |
| COL3A1 | collagen, type III, alpha 1 | -0.0255927 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0255187 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0253233 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0252583 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.0251514 |
| RPLP2 | ribosomal protein, large, P2 | -0.0248664 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | -0.024737 |
| MAP4 | microtubule-associated protein 4 | -0.0245312 |
| RPL28 | ribosomal protein L28 | -0.0244653 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0241099 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0240827 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0232713 |
| ARL15 | ADP-ribosylation factor-like 15 | -0.0228268 |
| AHNAK | AHNAK nucleoprotein | -0.0224843 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0224681 |
| RPL34 | ribosomal protein L34 | -0.0223058 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0220348 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0219344 |
| EHBP1 | EH domain binding protein 1 | -0.0214341 |
| KIFAP3 | kinesin-associated protein 3 | -0.0214147 |
| TDRD7 | tudor domain containing 7 | -0.0212651 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0210623 |
| HLA-C | major histocompatibility complex, class I, C | -0.0210463 |
| ANXA2 | annexin A2 | -0.0207009 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0204151 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0201583 |
| INSIG1 | insulin induced gene 1 | -0.0200091 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0199229 |
| TMOD1 | tropomodulin 1 | -0.0195474 |
| STC1 | stanniocalcin 1 | -0.0195327 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0195069 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0193848 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0191329 |
| RPL12 | ribosomal protein L12 | -0.0190738 |
| ANXA4 | annexin A4 | -0.0188488 |
| NDRG1 | N-myc downstream regulated 1 | -0.0188404 |
| RPS8 | ribosomal protein S8 | -0.0187803 |
| NF1 | neurofibromin 1 | -0.0182713 |
| SLFN5 | schlafen family member 5 | -0.0182709 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0182358 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0181849 |
| GOLGA4 | golgin A4 | -0.0181598 |
| RPL35A | ribosomal protein L35a | -0.0178725 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0177162 |
| RPS15 | ribosomal protein S15 | -0.0176742 |
| PXDN | peroxidasin | -0.0176683 |
| AGPAT3 | 1-acylglycerol-3-phosphate O-acyltransferase 3 | -0.0176275 |
| ATP13A3 | ATPase type 13A3 | -0.0175827 |
| RPL31 | ribosomal protein L31 | -0.0175017 |
| RPL26 | ribosomal protein L26 | -0.0174868 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0174231 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0173162 |
