| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Artesunate perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Artesunate_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.156734 |
| RPL3 | ribosomal protein L3 | 0.119438 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0969788 |
| TPM3 | tropomyosin 3 | 0.0825513 |
| LDHA | lactate dehydrogenase A | 0.0792735 |
| RRM2 | ribonucleotide reductase M2 | 0.0776564 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0751861 |
| PCBP2 | poly(rC) binding protein 2 | 0.0746359 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0742308 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0701597 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0681626 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0680148 |
| CALR | calreticulin | 0.0665741 |
| ASPH | aspartate beta-hydroxylase | 0.0652411 |
| HMGA2 | high mobility group AT-hook 2 | 0.0628686 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0600965 |
| HSPA8 | heat shock 70kDa protein 8 | 0.058647 |
| MCL1 | myeloid cell leukemia 1 | 0.0568859 |
| FTL | ferritin, light polypeptide | 0.0566538 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | 0.0555452 |
| CANX | calnexin | 0.0542955 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0533203 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0524717 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0520203 |
| RPL13A | ribosomal protein L13a | 0.048677 |
| VIM | vimentin | 0.048568 |
| HDGF | hepatoma-derived growth factor | 0.0471589 |
| SET | SET nuclear proto-oncogene | 0.0465278 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.045998 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0446938 |
| YAP1 | Yes-associated protein 1 | 0.0445007 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0438909 |
| RPL37 | ribosomal protein L37 | 0.0432924 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0431892 |
| CPNE1 | copine I | 0.0431089 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0429965 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0418683 |
| MMP12 | matrix metallopeptidase 12 | 0.0416473 |
| ANK2 | ankyrin 2, neuronal | 0.0410136 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.0405206 |
| JMJD1C | jumonji domain containing 1C | 0.040325 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.0397531 |
| ENO1 | enolase 1, (alpha) | 0.0397091 |
| AARS1 | alanyl-tRNA synthetase 1 | 0.0386309 |
| BRD2 | bromodomain containing 2 | 0.0377534 |
| EZR | ezrin | 0.037713 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0370659 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0368914 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0368651 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0359407 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0358812 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0355063 |
| RPS4X | ribosomal protein S4, X-linked | 0.0353251 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0350865 |
| ADAR | adenosine deaminase, RNA-specific | 0.0347481 |
| TPM4 | tropomyosin 4 | 0.0347185 |
| RPS12 | ribosomal protein S12 | 0.0345942 |
| FLNA | filamin A, alpha | 0.0342842 |
| IPO7 | importin 7 | 0.0341319 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0340615 |
| SPATS2 | spermatogenesis associated, serine-rich 2 | 0.0339204 |
| PRKCE | protein kinase C, epsilon | 0.0337557 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0336202 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0332286 |
| SESN2 | sestrin 2 | 0.0332232 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0330445 |
| MYL12B | myosin, light chain 12B, regulatory | 0.0328719 |
| TCP1 | t-complex 1 | 0.0325279 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.032178 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0319059 |
| VMP1 | vacuole membrane protein 1 | 0.0317546 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | 0.0315518 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0314378 |
| MSH6 | mutS homolog 6 | 0.0312677 |
| RTN4 | reticulon 4 | 0.0311627 |
| MAP1B | microtubule-associated protein 1B | 0.0308973 |
| TXNRD1 | thioredoxin reductase 1 | 0.0308829 |
| MKI67 | marker of proliferation Ki-67 | 0.0301358 |
| CHD4 | chromodomain helicase DNA binding protein 4 | 0.0301057 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0300381 |
| PCM1 | pericentriolar material 1 | 0.0297615 |
| MAGEA4 | melanoma antigen family A4 | 0.0296446 |
| PKM | pyruvate kinase, muscle | 0.0293096 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0291872 |
| CEP250 | centrosomal protein 250kDa | 0.0286427 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0286047 |
| WWOX | WW domain containing oxidoreductase | 0.0283028 |
| INTS6 | integrator complex subunit 6 | 0.0282201 |
| RPS8 | ribosomal protein S8 | 0.028017 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0279968 |
| DDIT3 | DNA-damage-inducible transcript 3 | 0.0278699 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.0275959 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.0275754 |
| RPL18A | ribosomal protein L18a | 0.0272786 |
| RPL37A | ribosomal protein L37a | 0.0269921 |
| APP | amyloid beta (A4) precursor protein | 0.0268963 |
| TAF1 | TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa | 0.0267792 |
| POTEF | POTE ankyrin domain family, member F | 0.0266034 |
| ERBIN | erbb2 interacting protein | 0.0265045 |
| RNF213 | ring finger protein 213 | 0.0264415 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CELF2 | CUGBP, Elav-like family member 2 | -0.07836 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0698264 |
| PCDH7 | protocadherin 7 | -0.0683484 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.067939 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0653527 |
| ZNF804A | zinc finger protein 804A | -0.0648829 |
| TMSB10 | thymosin beta 10 | -0.0607029 |
| MGAT4C | MGAT4 family, member C | -0.0585638 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0575522 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0542434 |
| CXADR | coxsackie virus and adenovirus receptor | -0.0532321 |
| NLGN1 | neuroligin 1 | -0.0515557 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0514027 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0480002 |
| DST | dystonin | -0.0454969 |
| EDN1 | endothelin 1 | -0.042159 |
| OXR1 | oxidation resistance 1 | -0.0416048 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.0413719 |
| TENM3 | teneurin transmembrane protein 3 | -0.0394018 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 | -0.0392838 |
| ECT2 | epithelial cell transforming 2 | -0.0369659 |
| KLF6 | Kruppel-like factor 6 | -0.0363896 |
| RPS24 | ribosomal protein S24 | -0.0349203 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | -0.0348156 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0342252 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | -0.0340697 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | -0.0337753 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0332412 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0327561 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0323058 |
| CDK6 | cyclin-dependent kinase 6 | -0.0314482 |
| SYT1 | synaptotagmin I | -0.0309219 |
| TMEM131 | transmembrane protein 131 | -0.0304684 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0302792 |
| TMEM123 | transmembrane protein 123 | -0.0300951 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0288634 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0288404 |
| NF1 | neurofibromin 1 | -0.0280082 |
| CEP95 | centrosomal protein 95kDa | -0.0279013 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0272255 |
| MTAP | methylthioadenosine phosphorylase | -0.02717 |
| MPG | N-methylpurine-DNA glycosylase | -0.0271474 |
| PRR16 | proline rich 16 | -0.0270509 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | -0.0270103 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0269004 |
| LMO7 | LIM domain 7 | -0.0268794 |
| CRISPLD1 | cysteine-rich secretory protein LCCL domain containing 1 | -0.0265987 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0264562 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0259612 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0258945 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0252838 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.025272 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0252011 |
| POU2F1 | POU class 2 homeobox 1 | -0.0249406 |
| GASK1B | golgi associated kinase 1B | -0.0249382 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.024771 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0247091 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0247075 |
| ZFP91 | ZFP91 zinc finger protein | -0.0243521 |
| WDR43 | WD repeat domain 43 | -0.0243111 |
| RPL6 | ribosomal protein L6 | -0.0242651 |
| CDK17 | cyclin-dependent kinase 17 | -0.0238269 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0236722 |
| NEK7 | NIMA-related kinase 7 | -0.0230177 |
| TMEM41B | transmembrane protein 41B | -0.0229351 |
| KLHL24 | kelch-like family member 24 | -0.022895 |
| CENPE | centromere protein E, 312kDa | -0.0227013 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.022442 |
| MYPN | myopalladin | -0.0224419 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0223816 |
| DHX36 | DEAH (Asp-Glu-Ala-His) box polypeptide 36 | -0.0222047 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | -0.022181 |
| ZNF217 | zinc finger protein 217 | -0.0220983 |
| OSBPL8 | oxysterol binding protein-like 8 | -0.022084 |
| ETNK1 | ethanolamine kinase 1 | -0.021864 |
| CLDN1 | claudin 1 | -0.021722 |
| KIF5B | kinesin family member 5B | -0.0216511 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0213989 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0213604 |
| TWSG1 | twisted gastrulation BMP signaling modulator 1 | -0.0212901 |
| BIRC2 | baculoviral IAP repeat containing 2 | -0.0211622 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.021117 |
| EDARADD | EDAR-associated death domain | -0.0209801 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.0208404 |
| PCNP | PEST proteolytic signal containing nuclear protein | -0.0208278 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.020714 |
| RPL26 | ribosomal protein L26 | -0.0206451 |
| RAP1GDS1 | RAP1, GTP-GDP dissociation stimulator 1 | -0.0205664 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.0202632 |
| CARD16 | caspase recruitment domain family, member 16 | -0.0197656 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0195997 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0194244 |
| MEMO1 | mediator of cell motility 1 | -0.0191005 |
| CCNG1 | cyclin G1 | -0.0190348 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.0190051 |
| RASAL2 | RAS protein activator like 2 | -0.0188672 |
| PRR11 | proline rich 11 | -0.0187277 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0186031 |
| TCERG1 | transcription elongation regulator 1 | -0.0185034 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0180266 |
