| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Artesunate perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Artesunate_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.153392 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.129605 |
| DSCAM | Down syndrome cell adhesion molecule | 0.110431 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0890403 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0808981 |
| ITGA6 | integrin, alpha 6 | 0.0782305 |
| SMAD3 | SMAD family member 3 | 0.0704849 |
| CANX | calnexin | 0.0678516 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0665662 |
| STK24 | serine/threonine kinase 24 | 0.064964 |
| APP | amyloid beta (A4) precursor protein | 0.0634529 |
| IFNGR1 | interferon gamma receptor 1 | 0.0624897 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0599869 |
| ADAR | adenosine deaminase, RNA-specific | 0.0578211 |
| LDHA | lactate dehydrogenase A | 0.0569536 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0562536 |
| ATP11A | ATPase, class VI, type 11A | 0.0560353 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0559837 |
| EPHB2 | EPH receptor B2 | 0.0558844 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0554434 |
| SPATA13 | spermatogenesis associated 13 | 0.0502019 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0497789 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.045823 |
| PHF3 | PHD finger protein 3 | 0.0453075 |
| FAT1 | FAT atypical cadherin 1 | 0.044648 |
| MCL1 | myeloid cell leukemia 1 | 0.0445283 |
| ANXA2 | annexin A2 | 0.0438098 |
| KRT18 | keratin 18, type I | 0.0437876 |
| EZR | ezrin | 0.0430365 |
| SDC4 | syndecan 4 | 0.0419532 |
| C6ORF132 | chromosome 6 open reading frame 132 | 0.0417257 |
| MLPH | melanophilin | 0.0414675 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0405264 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.040082 |
| PADI1 | peptidyl arginine deiminase, type I | 0.0395646 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0395391 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0394393 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0385343 |
| MUC13 | mucin 13, cell surface associated | 0.0384772 |
| MYO1E | myosin IE | 0.0373531 |
| PRSS3 | protease, serine, 3 | 0.0363061 |
| COPA | coatomer protein complex, subunit alpha | 0.0362321 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0354052 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0336331 |
| HDLBP | high density lipoprotein binding protein | 0.0334591 |
| RNF43 | ring finger protein 43 | 0.0332371 |
| TC2N | tandem C2 domains, nuclear | 0.0327412 |
| SEPTIN9 | septin 9 | 0.0326125 |
| TPM3 | tropomyosin 3 | 0.0324275 |
| SLK | STE20-like kinase | 0.0320257 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.031871 |
| BCL2L1 | BCL2-like 1 | 0.0317091 |
| YAP1 | Yes-associated protein 1 | 0.0316433 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0315174 |
| DUSP16 | dual specificity phosphatase 16 | 0.0314157 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0311196 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0304446 |
| CTSB | cathepsin B | 0.0303284 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0299845 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.029796 |
| NCKAP5 | NCK-associated protein 5 | 0.0293371 |
| LCN2 | lipocalin 2 | 0.0286277 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0281071 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0280934 |
| RPL3 | ribosomal protein L3 | 0.0280338 |
| VPS37B | vacuolar protein sorting 37 homolog B (S. cerevisiae) | 0.027924 |
| DSPP | dentin sialophosphoprotein | 0.0277848 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | 0.0275715 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0274138 |
| CDHR2 | cadherin-related family member 2 | 0.0273524 |
| GOLGA3 | golgin A3 | 0.0273119 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.0272963 |
| ARHGEF10L | Rho guanine nucleotide exchange factor (GEF) 10-like | 0.0270399 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0270113 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0269827 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0266531 |
| ANXA11 | annexin A11 | 0.0265056 |
| OARD1 | O-acyl-ADP-ribose deacylase 1 | 0.0264591 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.0263626 |
| RBM33 | RNA binding motif protein 33 | 0.0262399 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0258702 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0258194 |
| BICRAL | BICRA like chromatin remodeling complex associated protein | 0.0257503 |
| MYO10 | myosin X | 0.025647 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.025568 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0254868 |
| ACTN4 | actinin, alpha 4 | 0.0252953 |
| RUNX1 | runt-related transcription factor 1 | 0.0252067 |
| CDK5RAP3 | CDK5 regulatory subunit associated protein 3 | 0.0250988 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0248374 |
| YBX3 | Y box binding protein 3 | 0.0246904 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0246769 |
| SFTPA2 | surfactant protein A2 | 0.0246691 |
| ABHD2 | abhydrolase domain containing 2 | 0.0243119 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.024169 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0241182 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0240978 |
| SMYD3 | SET and MYND domain containing 3 | 0.024089 |
| CTBP2 | C-terminal binding protein 2 | 0.0239838 |
| ATP10B | ATPase, class V, type 10B | 0.0239619 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NPSR1 | neuropeptide S receptor 1 | -0.120328 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.119888 |
| FNDC3B | fibronectin type III domain containing 3B | -0.114496 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.100797 |
| INTS6 | integrator complex subunit 6 | -0.0986673 |
| PRKCA | protein kinase C, alpha | -0.0751007 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.074538 |
| NDRG1 | N-myc downstream regulated 1 | -0.0686667 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0661589 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0602955 |
| XAF1 | XIAP associated factor 1 | -0.0596095 |
| STS | steroid sulfatase (microsomal), isozyme S | -0.0569674 |
| LYZ | lysozyme | -0.0543836 |
| PLSCR2 | phospholipid scramblase 2 | -0.0539257 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.053273 |
| EGR1 | early growth response 1 | -0.0531731 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | -0.0529862 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.052936 |
| SP100 | SP100 nuclear antigen | -0.0524514 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0513527 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0495556 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0471771 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0468937 |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 | -0.0464418 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | -0.0452171 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0442619 |
| RIGI | RNA sensor RIG-I | -0.0435807 |
| PLSCR1 | phospholipid scramblase 1 | -0.0431803 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0421341 |
| ERBIN | erbb2 interacting protein | -0.0410751 |
| MUC20 | mucin 20, cell surface associated | -0.0403405 |
| VCL | vinculin | -0.0398871 |
| CSTPP1 | centriolar satellite-associated tubulin polyglutamylase complex regulator 1 | -0.0392748 |
| VMP1 | vacuole membrane protein 1 | -0.0384755 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0383593 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0381515 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0381216 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0377846 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0376522 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.036072 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0357565 |
| TXNIP | thioredoxin interacting protein | -0.0351037 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | -0.0340952 |
| H1-0 | H1.0 linker histone | -0.0333108 |
| SSH2 | slingshot protein phosphatase 2 | -0.0333107 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0320403 |
| RAD51B | RAD51 paralog B | -0.0309859 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0307426 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0306944 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0303215 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | -0.0295559 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0295394 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.028802 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0283194 |
| CCDC146 | coiled-coil domain containing 146 | -0.0279409 |
| POF1B | premature ovarian failure, 1B | -0.0277826 |
| TMSB10 | thymosin beta 10 | -0.0275592 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.027388 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0272959 |
| PTMA | prothymosin, alpha | -0.0269675 |
| RNF213 | ring finger protein 213 | -0.0268233 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0268036 |
| APOL1 | apolipoprotein L, 1 | -0.0266155 |
| MT2A | metallothionein 2A | -0.0263229 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0263226 |
| SQSTM1 | sequestosome 1 | -0.0261581 |
| SAMD9L | sterile alpha motif domain containing 9-like | -0.0260476 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.0259925 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0256803 |
| PCED1B | PC-esterase domain containing 1B | -0.0256731 |
| CMIP | c-Maf inducing protein | -0.0255942 |
| FBXO39 | F-box protein 39 | -0.0253356 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0252828 |
| ESRP1 | epithelial splicing regulatory protein 1 | -0.0249741 |
| CSTB | cystatin B (stefin B) | -0.0246351 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0245962 |
| B3GALT5 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5 | -0.0239918 |
| DYNC2I1 | dynein 2 intermediate chain 1 | -0.0238216 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0237296 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | -0.023441 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0233772 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0231455 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0230221 |
| HLA-B | major histocompatibility complex, class I, B | -0.0227654 |
| PTGR1 | prostaglandin reductase 1 | -0.0227478 |
| UBE2R2 | ubiquitin-conjugating enzyme E2R 2 | -0.0223005 |
| FTL | ferritin, light polypeptide | -0.0216398 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0215788 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0214836 |
| CTSD | cathepsin D | -0.0212355 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0212143 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0211702 |
| SCARB1 | scavenger receptor class B, member 1 | -0.0211253 |
| AREG | amphiregulin | -0.0208881 |
| DGKH | diacylglycerol kinase, eta | -0.0207931 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | -0.0207551 |
| FHIT | fragile histidine triad | -0.0206534 |
| DSCAML1 | Down syndrome cell adhesion molecule like 1 | -0.0202104 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0200937 |
| JAK1 | Janus kinase 1 | -0.0200453 |
