| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Artesunate perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Artesunate_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.356692 |
| COL6A3 | collagen, type VI, alpha 3 | 0.33628 |
| VEGFA | vascular endothelial growth factor A | 0.208035 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.166898 |
| LDHA | lactate dehydrogenase A | 0.141881 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.140411 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0845491 |
| RPL3 | ribosomal protein L3 | 0.078077 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0752588 |
| CANX | calnexin | 0.0693818 |
| APP | amyloid beta (A4) precursor protein | 0.0590262 |
| INHBA | inhibin, beta A | 0.0582334 |
| PLEC | plectin | 0.0580498 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0574128 |
| FLNA | filamin A, alpha | 0.0531601 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | 0.0504727 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0466501 |
| COL6A1 | collagen, type VI, alpha 1 | 0.0435549 |
| MSN | moesin | 0.0431731 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0415058 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0411417 |
| ASPH | aspartate beta-hydroxylase | 0.0408868 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0383052 |
| SMAD3 | SMAD family member 3 | 0.0364724 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.035935 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0347055 |
| FBN1 | fibrillin 1 | 0.0336709 |
| CALR | calreticulin | 0.0331053 |
| MYO10 | myosin X | 0.0312121 |
| COL4A1 | collagen, type IV, alpha 1 | 0.0304796 |
| SDC2 | syndecan 2 | 0.0293953 |
| RPL18A | ribosomal protein L18a | 0.0292847 |
| ACTN1 | actinin, alpha 1 | 0.028508 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0282198 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0280256 |
| RPL13A | ribosomal protein L13a | 0.0278375 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | 0.02625 |
| POSTN | periostin, osteoblast specific factor | 0.0261729 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0257317 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0256846 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0255823 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0247494 |
| HMGA2 | high mobility group AT-hook 2 | 0.0244869 |
| TPM3 | tropomyosin 3 | 0.0243976 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0243389 |
| FAM107B | family with sequence similarity 107, member B | 0.0235766 |
| IER2 | immediate early response 2 | 0.0228354 |
| MCL1 | myeloid cell leukemia 1 | 0.0227861 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0222298 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0218824 |
| COL1A2 | collagen, type I, alpha 2 | 0.0218684 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.021799 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.0215712 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.021401 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0209764 |
| AXL | AXL receptor tyrosine kinase | 0.0209356 |
| SVIL | supervillin | 0.0208016 |
| HDLBP | high density lipoprotein binding protein | 0.020748 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.02058 |
| NAV1 | neuron navigator 1 | 0.020453 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.020343 |
| BRD2 | bromodomain containing 2 | 0.0203147 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0202047 |
| AMOTL1 | angiomotin like 1 | 0.020115 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0200848 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0200172 |
| TNS1 | tensin 1 | 0.020011 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0197576 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0197452 |
| RPS4X | ribosomal protein S4, X-linked | 0.0195822 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0195422 |
| COPG1 | coatomer protein complex, subunit gamma 1 | 0.0195236 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0190995 |
| TPM4 | tropomyosin 4 | 0.019029 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.0183703 |
| PCBP2 | poly(rC) binding protein 2 | 0.0179831 |
| ARRDC3 | arrestin domain containing 3 | 0.0179458 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0179313 |
| CPNE1 | copine I | 0.017834 |
| OPTN | optineurin | 0.01769 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0176174 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | 0.0174058 |
| SEPTIN9 | septin 9 | 0.0173636 |
| MNMIP1 | manchette microtubule inner protein 1 | 0.0172838 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0171921 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | 0.0171535 |
| PPP1R18 | protein phosphatase 1, regulatory subunit 18 | 0.0171431 |
| SET | SET nuclear proto-oncogene | 0.0170539 |
| PRSS23 | protease, serine, 23 | 0.0168852 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0167931 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0167667 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0166356 |
| ITGB5 | integrin, beta 5 | 0.0165705 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0165658 |
| PLXNA1 | plexin A1 | 0.0165068 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0163492 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0162875 |
| HDAC9 | histone deacetylase 9 | 0.0162825 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0161066 |
| FAT1 | FAT atypical cadherin 1 | 0.0160842 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.209686 |
| FN1 | fibronectin 1 | -0.176246 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.172691 |
| VIM | vimentin | -0.140885 |
| COL1A1 | collagen, type I, alpha 1 | -0.138771 |
| TMSB10 | thymosin beta 10 | -0.124194 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.120036 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.116495 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0896484 |
| CADM1 | cell adhesion molecule 1 | -0.0805844 |
| IER3 | immediate early response 3 | -0.0738875 |
| CDH13 | cadherin 13 | -0.0720564 |
| LOX | lysyl oxidase | -0.0636208 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0615325 |
| RPS6 | ribosomal protein S6 | -0.0600791 |
| RPS8 | ribosomal protein S8 | -0.0588001 |
| NDRG1 | N-myc downstream regulated 1 | -0.0567598 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0542099 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0529682 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.052514 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0485752 |
| FTL | ferritin, light polypeptide | -0.0467234 |
| ACTG1 | actin gamma 1 | -0.0431091 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0429761 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0425421 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0424163 |
| MTDH | metadherin | -0.0421028 |
| MT2A | metallothionein 2A | -0.0416838 |
| IL6ST | interleukin 6 signal transducer | -0.0400176 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0394987 |
| PTMA | prothymosin, alpha | -0.0390085 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0388732 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.038242 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0350312 |
| RPL35A | ribosomal protein L35a | -0.0346129 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.034341 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0343008 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.033794 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0329981 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0329451 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | -0.0328974 |
| MAP4 | microtubule-associated protein 4 | -0.03166 |
| SMYD3 | SET and MYND domain containing 3 | -0.0306891 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0303157 |
| CUX1 | cut-like homeobox 1 | -0.0297917 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0296042 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0291426 |
| RPL28 | ribosomal protein L28 | -0.0289727 |
| CA12 | carbonic anhydrase XII | -0.0283104 |
| CNTN5 | contactin 5 | -0.0279883 |
| S100A9 | S100 calcium binding protein A9 | -0.0279438 |
| RPL5 | ribosomal protein L5 | -0.0271754 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0265318 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0261469 |
| RPL34 | ribosomal protein L34 | -0.0261122 |
| PALLD | palladin, cytoskeletal associated protein | -0.0254683 |
| PRELID2 | PRELI domain containing 2 | -0.0253918 |
| PPP3CC | protein phosphatase 3, catalytic subunit, gamma isozyme | -0.0251976 |
| CAVIN1 | caveolae associated protein 1 | -0.0251944 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0248653 |
| KIF13A | kinesin family member 13A | -0.0246916 |
| UBC | ubiquitin C | -0.0246677 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.0242521 |
| PXDN | peroxidasin | -0.0242315 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0240855 |
| EHD2 | EH-domain containing 2 | -0.0240445 |
| WASF2 | WAS protein family, member 2 | -0.0239516 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0239503 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0239466 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0238584 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0237974 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.0236648 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0234413 |
| RACK1 | receptor for activated C kinase 1 | -0.0233372 |
| RPS25 | ribosomal protein S25 | -0.0231991 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0229244 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0228912 |
| GOLGB1 | golgin B1 | -0.0226621 |
| QKI | QKI, KH domain containing, RNA binding | -0.0225834 |
| BNC2 | basonuclin 2 | -0.0225274 |
| RPL26 | ribosomal protein L26 | -0.0222211 |
| RPLP1 | ribosomal protein, large, P1 | -0.0222093 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) | -0.0219799 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.021871 |
| ZNF292 | zinc finger protein 292 | -0.0218624 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.021794 |
| BBX | bobby sox homolog (Drosophila) | -0.0217772 |
| S100A6 | S100 calcium binding protein A6 | -0.0214848 |
| RPS24 | ribosomal protein S24 | -0.0211399 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0208036 |
| RPL12 | ribosomal protein L12 | -0.020714 |
| RPS19 | ribosomal protein S19 | -0.0206758 |
| RPLP2 | ribosomal protein, large, P2 | -0.0205546 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.020547 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0204854 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0204852 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0204833 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0204816 |
| SQSTM1 | sequestosome 1 | -0.0203817 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0203412 |
