| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Artesunate perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Artesunate_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.136168 |
| LDHA | lactate dehydrogenase A | 0.134332 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.122913 |
| TGM2 | transglutaminase 2 | 0.0750166 |
| PODXL | podocalyxin-like | 0.0714569 |
| PLEC | plectin | 0.0670607 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.063671 |
| MSN | moesin | 0.0564175 |
| RPL3 | ribosomal protein L3 | 0.0554494 |
| SULF2 | sulfatase 2 | 0.0518043 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0498931 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.048702 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 0.046645 |
| BLCAP | bladder cancer associated protein | 0.0452138 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0419635 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0418503 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | 0.0416266 |
| AOPEP | aminopeptidase O (putative) | 0.0413651 |
| SLK | STE20-like kinase | 0.0412854 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0391312 |
| AMOTL1 | angiomotin like 1 | 0.0380542 |
| BCL2L1 | BCL2-like 1 | 0.0378121 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0365802 |
| CPNE1 | copine I | 0.0351368 |
| RPL13A | ribosomal protein L13a | 0.0345553 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0341794 |
| LUZP1 | leucine zipper protein 1 | 0.034168 |
| MECOM | MDS1 and EVI1 complex locus | 0.0337881 |
| ADAR | adenosine deaminase, RNA-specific | 0.0336008 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0332567 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0331622 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0331369 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0326983 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0326168 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0324309 |
| APP | amyloid beta (A4) precursor protein | 0.0317284 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0316092 |
| RPL18A | ribosomal protein L18a | 0.0311249 |
| KIAA1671 | KIAA1671 | 0.0310531 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0299706 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0299 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.0298487 |
| RAI14 | retinoic acid induced 14 | 0.029707 |
| RPS4X | ribosomal protein S4, X-linked | 0.0296559 |
| OSMR | oncostatin M receptor | 0.0289944 |
| MEGF6 | multiple EGF-like-domains 6 | 0.0286708 |
| EHBP1L1 | EH domain binding protein 1-like 1 | 0.0286515 |
| MEIS2 | Meis homeobox 2 | 0.027425 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0274046 |
| TENM4 | teneurin transmembrane protein 4 | 0.0273606 |
| FAM107B | family with sequence similarity 107, member B | 0.0273302 |
| FRMD6 | FERM domain containing 6 | 0.0273162 |
| PRSS23 | protease, serine, 23 | 0.0266412 |
| LAMC2 | laminin, gamma 2 | 0.0265881 |
| FOXP1 | forkhead box P1 | 0.0247516 |
| ARHGAP23 | Rho GTPase activating protein 23 | 0.0247386 |
| SEPTIN9 | septin 9 | 0.0245645 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0239675 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0237154 |
| EGR1 | early growth response 1 | 0.0229226 |
| RPL37 | ribosomal protein L37 | 0.0228831 |
| HLA-A | major histocompatibility complex, class I, A | 0.022596 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0225371 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0224977 |
| HLA-E | major histocompatibility complex, class I, E | 0.0224938 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0224297 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0224138 |
| PLXNA2 | plexin A2 | 0.0219849 |
| MCL1 | myeloid cell leukemia 1 | 0.0216421 |
| CNTNAP3 | contactin associated protein-like 3 | 0.021537 |
| IFI44L | interferon-induced protein 44-like | 0.0215069 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | 0.0212743 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0211763 |
| DOK5 | docking protein 5 | 0.0209874 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0196815 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0196533 |
| ANXA11 | annexin A11 | 0.0196324 |
| MTAP | methylthioadenosine phosphorylase | 0.0195633 |
| EFNA5 | ephrin-A5 | 0.0195005 |
| MKI67 | marker of proliferation Ki-67 | 0.0194012 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0192902 |
| RASAL2 | RAS protein activator like 2 | 0.0192006 |
| KLF3 | Kruppel-like factor 3 (basic) | 0.0188803 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0186383 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0184007 |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 | 0.0183154 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0183025 |
| RNF217 | ring finger protein 217 | 0.0182547 |
| MTSS1 | metastasis suppressor 1 | 0.0180512 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0178888 |
| ACTN1 | actinin, alpha 1 | 0.0178661 |
| DUSP4 | dual specificity phosphatase 4 | 0.0178629 |
| CLU | clusterin | 0.017857 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0178349 |
| TXNIP | thioredoxin interacting protein | 0.0177461 |
| PITPNB | phosphatidylinositol transfer protein, beta | 0.0176596 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0176393 |
| DHX34 | DEAH (Asp-Glu-Ala-His) box polypeptide 34 | 0.0176294 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0175478 |
| SIK3 | SIK family kinase 3 | 0.017525 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.146497 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.14641 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.137215 |
| TMSB10 | thymosin beta 10 | -0.109747 |
| ENO1 | enolase 1, (alpha) | -0.0985016 |
| PTMA | prothymosin, alpha | -0.0959414 |
| KRT17 | keratin 17, type I | -0.0890991 |
| UBC | ubiquitin C | -0.0813774 |
| STC1 | stanniocalcin 1 | -0.0697411 |
| RPS27A | ribosomal protein S27a | -0.0671803 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0665269 |
| GOLGA4 | golgin A4 | -0.0660754 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.064963 |
| RBM39 | RNA binding motif protein 39 | -0.0613636 |
| AHNAK | AHNAK nucleoprotein | -0.0590205 |
| POTEF | POTE ankyrin domain family, member F | -0.056762 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0512364 |
| LMNA | lamin A/C | -0.0502575 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.049537 |
| NDRG1 | N-myc downstream regulated 1 | -0.0495148 |
| KRT6A | keratin 6A, type II | -0.049271 |
| SERINC3 | serine incorporator 3 | -0.0488523 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0479542 |
| NAV2 | neuron navigator 2 | -0.0471058 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.046952 |
| FNIP1 | folliculin interacting protein 1 | -0.0467654 |
| S100A10 | S100 calcium binding protein A10 | -0.0463389 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0461648 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0461265 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0455151 |
| RPLP2 | ribosomal protein, large, P2 | -0.0451571 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0450407 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0450106 |
| TOP1 | topoisomerase (DNA) I | -0.0449371 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0449055 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0446121 |
| OGA | O-GlcNAcase | -0.0439244 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0437341 |
| UBE2V1 | ubiquitin-conjugating enzyme E2 variant 1 | -0.0431263 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0425421 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0411231 |
| RPS21 | ribosomal protein S21 | -0.041022 |
| WASF2 | WAS protein family, member 2 | -0.0409208 |
| EMP1 | epithelial membrane protein 1 | -0.0401814 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0399415 |
| DSTN | destrin (actin depolymerizing factor) | -0.0394794 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0394095 |
| PKM | pyruvate kinase, muscle | -0.0393368 |
| CALU | calumenin | -0.0392325 |
| COG5 | component of oligomeric golgi complex 5 | -0.0386936 |
| ITGA6 | integrin, alpha 6 | -0.0375703 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0374586 |
| INTS6 | integrator complex subunit 6 | -0.0373013 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0370454 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0368731 |
| S100A6 | S100 calcium binding protein A6 | -0.0368206 |
| SUCO | SUN domain containing ossification factor | -0.0360037 |
| MORF4L2 | mortality factor 4 like 2 | -0.035798 |
| SPAG9 | sperm associated antigen 9 | -0.0357586 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0356481 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0348512 |
| YAP1 | Yes-associated protein 1 | -0.0347198 |
| ANXA2 | annexin A2 | -0.0345041 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0344212 |
| ANXA1 | annexin A1 | -0.0342267 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0339359 |
| HM13 | histocompatibility (minor) 13 | -0.0339248 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0336623 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0336189 |
| FSCN1 | fascin actin-bundling protein 1 | -0.0336138 |
| CALR | calreticulin | -0.0335781 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0335771 |
| SRP54 | signal recognition particle 54kDa | -0.0333048 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0332807 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0332748 |
| ARF4 | ADP-ribosylation factor 4 | -0.0331338 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0329893 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0327631 |
| COG6 | component of oligomeric golgi complex 6 | -0.0322904 |
| CANX | calnexin | -0.0322594 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0320867 |
| RPS8 | ribosomal protein S8 | -0.0320645 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | -0.0318436 |
| RPS6 | ribosomal protein S6 | -0.0314557 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0310884 |
| ANLN | anillin, actin binding protein | -0.0310857 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0310057 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | -0.0309193 |
| ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif, 16 | -0.0307744 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.030675 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0305186 |
| SBF2 | SET binding factor 2 | -0.0304532 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0303293 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0302807 |
| RPL23 | ribosomal protein L23 | -0.0298318 |
| RPS3 | ribosomal protein S3 | -0.0290334 |
| RPS25 | ribosomal protein S25 | -0.0288074 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0282015 |
| RPS24 | ribosomal protein S24 | -0.0280797 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | -0.0278835 |
