| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Artesunate perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Artesunate_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| KRT18 | keratin 18, type I | 0.245142 |
| LDHA | lactate dehydrogenase A | 0.225652 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.105551 |
| RPL3 | ribosomal protein L3 | 0.0938492 |
| AREG | amphiregulin | 0.0895185 |
| FAT1 | FAT atypical cadherin 1 | 0.0888352 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0827733 |
| LMO7 | LIM domain 7 | 0.0777702 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0751958 |
| ITGA6 | integrin, alpha 6 | 0.0691312 |
| DSPP | dentin sialophosphoprotein | 0.0640974 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0576224 |
| RPL13A | ribosomal protein L13a | 0.0572562 |
| TPM4 | tropomyosin 4 | 0.0567517 |
| EZR | ezrin | 0.0562532 |
| LAMA4 | laminin, alpha 4 | 0.0551262 |
| ONECUT3 | one cut homeobox 3 | 0.0511189 |
| ANXA2 | annexin A2 | 0.0499945 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0490263 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0484546 |
| APP | amyloid beta (A4) precursor protein | 0.0424866 |
| MUC13 | mucin 13, cell surface associated | 0.0417444 |
| MT2A | metallothionein 2A | 0.0409719 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0408582 |
| KRT19 | keratin 19, type I | 0.0406798 |
| RPL18A | ribosomal protein L18a | 0.0403231 |
| H1-0 | H1.0 linker histone | 0.0398416 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0396851 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0395181 |
| PGK1 | phosphoglycerate kinase 1 | 0.0387002 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0383416 |
| PRSS3 | protease, serine, 3 | 0.0382746 |
| ASPH | aspartate beta-hydroxylase | 0.0381847 |
| TMEM45B | transmembrane protein 45B | 0.0360784 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0359856 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0354213 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0351937 |
| ANXA11 | annexin A11 | 0.0351534 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.034869 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0345613 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0344799 |
| RPS4X | ribosomal protein S4, X-linked | 0.0342057 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0336619 |
| LAMC2 | laminin, gamma 2 | 0.0333829 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0328714 |
| KLF3 | Kruppel-like factor 3 (basic) | 0.0325196 |
| FLNB | filamin B, beta | 0.0322812 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0316909 |
| MCL1 | myeloid cell leukemia 1 | 0.0316541 |
| KRT8 | keratin 8, type II | 0.0315976 |
| TPM3 | tropomyosin 3 | 0.0308596 |
| PLEC | plectin | 0.0304409 |
| ENO1 | enolase 1, (alpha) | 0.0301109 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0300364 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0298247 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0297698 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0297137 |
| CADPS | Ca++-dependent secretion activator | 0.029278 |
| SVIL | supervillin | 0.0282058 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0274321 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.027336 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | 0.0270342 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0267231 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0264181 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0256554 |
| KLF6 | Kruppel-like factor 6 | 0.025392 |
| MYOF | myoferlin | 0.0245998 |
| EMP1 | epithelial membrane protein 1 | 0.0244953 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0242416 |
| LAMB3 | laminin, beta 3 | 0.0239378 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0239267 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0237178 |
| VEGFA | vascular endothelial growth factor A | 0.0236518 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0232884 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0232498 |
| MYH14 | myosin, heavy chain 14, non-muscle | 0.0231373 |
| MT1E | metallothionein 1E | 0.0230154 |
| CANX | calnexin | 0.0230082 |
| FLNA | filamin A, alpha | 0.0229602 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0228775 |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) | 0.0227609 |
| LIPH | lipase, member H | 0.022647 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0224906 |
| TRIM2 | tripartite motif containing 2 | 0.0224289 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0219745 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.0219413 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0215137 |
| QSOX1 | quiescin Q6 sulfhydryl oxidase 1 | 0.021506 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0212078 |
| ABHD2 | abhydrolase domain containing 2 | 0.0210886 |
| SH3D19 | SH3 domain containing 19 | 0.020862 |
| MYO18A | myosin XVIIIA | 0.0207735 |
| CLDN4 | claudin 4 | 0.0207088 |
| ADAM19 | ADAM metallopeptidase domain 19 | 0.0200762 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.020002 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.0199841 |
| MT1X | metallothionein 1X | 0.0194035 |
| TMSB4X | thymosin beta 4, X-linked | 0.0185332 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.018494 |
| USP6NL | USP6 N-terminal like | 0.01831 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.178239 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.163581 |
| NPSR1 | neuropeptide S receptor 1 | -0.156292 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.146048 |
| RPS6 | ribosomal protein S6 | -0.127264 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | -0.11819 |
| PTMA | prothymosin, alpha | -0.111976 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0993061 |
| GPHN | gephyrin | -0.0989046 |
| GOLGA4 | golgin A4 | -0.0843672 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0660103 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0604412 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0585443 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0560147 |
| RPLP2 | ribosomal protein, large, P2 | -0.0527538 |
| RPS2 | ribosomal protein S2 | -0.0467638 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0463146 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0462456 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0461846 |
| RPL34 | ribosomal protein L34 | -0.0446875 |
| HMGA1 | high mobility group AT-hook 1 | -0.0442893 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0441497 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0437907 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0425311 |
| RPS8 | ribosomal protein S8 | -0.0417258 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0408028 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0405207 |
| RBM39 | RNA binding motif protein 39 | -0.0398549 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0396931 |
| RPL36 | ribosomal protein L36 | -0.0388935 |
| COG5 | component of oligomeric golgi complex 5 | -0.0382436 |
| RPS25 | ribosomal protein S25 | -0.0381052 |
| RPLP1 | ribosomal protein, large, P1 | -0.0380081 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0371837 |
| RPS19 | ribosomal protein S19 | -0.0371112 |
| RPS23 | ribosomal protein S23 | -0.036475 |
| TFF3 | trefoil factor 3 (intestinal) | -0.0362953 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0360463 |
| AGR2 | anterior gradient 2 | -0.0360219 |
| RPS29 | ribosomal protein S29 | -0.0358589 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0351165 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0350371 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0349358 |
| SETD5 | SET domain containing 5 | -0.034841 |
| NFIA | nuclear factor I/A | -0.0335791 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0332319 |
| ZNF292 | zinc finger protein 292 | -0.032037 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0314746 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0312479 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0312223 |
| SBF2 | SET binding factor 2 | -0.0311158 |
| S100A6 | S100 calcium binding protein A6 | -0.0310335 |
| RPS16 | ribosomal protein S16 | -0.030872 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0304763 |
| MAP4 | microtubule-associated protein 4 | -0.0301871 |
| RPL37A | ribosomal protein L37a | -0.0298527 |
| INSIG1 | insulin induced gene 1 | -0.029836 |
| RTN3 | reticulon 3 | -0.0298102 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0297334 |
| MED13L | mediator complex subunit 13-like | -0.0297235 |
| PTEN | phosphatase and tensin homolog | -0.0297112 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0296561 |
| FAM13A | family with sequence similarity 13, member A | -0.0294474 |
| PRRC2C | proline-rich coiled-coil 2C | -0.029429 |
| RPS24 | ribosomal protein S24 | -0.0291864 |
| RPL5 | ribosomal protein L5 | -0.0291158 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.028687 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.028627 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0286156 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.028517 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0284061 |
| RPL21 | ribosomal protein L21 | -0.0282829 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0281607 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0280591 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0277583 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | -0.0276309 |
| ESRP1 | epithelial splicing regulatory protein 1 | -0.0273975 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | -0.0273125 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0272831 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0271616 |
| RPS21 | ribosomal protein S21 | -0.0270979 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0267694 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0266532 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | -0.0266061 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0265583 |
| NKTR | natural killer cell triggering receptor | -0.0264863 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.0264087 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0263935 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0263141 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0263098 |
| CBX3 | chromobox homolog 3 | -0.0262338 |
| CLTC | clathrin, heavy chain (Hc) | -0.026106 |
| MLEC | malectin | -0.0257778 |
| SEC24D | SEC24 family member D | -0.02515 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.025069 |
| SSR1 | signal sequence receptor, alpha | -0.0249179 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0248562 |
| CALR | calreticulin | -0.0248086 |
| CDK13 | cyclin-dependent kinase 13 | -0.0246849 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0246659 |
